PCL-2 is a reactive oxygen species-responsive fluorescent probe targeting hydrogen peroxide. It selectively reacts with hydrogen peroxide to produce 6-hydroxy-2-cyanobenzothiazole, exhibiting minimal response to other biologically relevant reactive oxygen species. PCL-2 is suitable for chemoselective imaging of hydrogen peroxide in in vitro models and can be applied in acute inflammation research using mouse models. This probe allows for the investigation of hydrogen peroxide's role in acute inflammatory processes.
PCL-2 is a reactive oxygen species-responsive fluorescent probe targeting hydrogen peroxide. It selectively reacts with hydrogen peroxide to produce 6-hydroxy-2-cyanobenzothiazole, exhibiting minimal response to other biologically relevant reactive oxygen species. PCL-2 is suitable for chemoselective imaging of hydrogen peroxide in in vitro models and can be applied in acute inflammation research using mouse models. This probe allows for the investigation of hydrogen peroxide's role in acute inflammatory processes.
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