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Cholinesterase (ChE) Inhibitor
Corydaline is an isoquinoline alkaloid that functions as a cholinesterase (ChE) inhibitor with an IC50 of 226 μM. In addition to its cholinergic activity, Corydaline acts as a μ-opioid receptor agonist (Ki of 1.23 μM) and demonstrates significant antiviral effects by inhibiting enterovirus 71 (EV71) replication, with an IC50 of 25.23 μM. This compound also exhibits anti-angiogenic, anti-allergic, gastric-emptying, and antinociceptive properties, making it a valuable reagent for various biological research applications.
