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Catalog No.
Product Name
Application
Product Information
Product Citation
dual MDM2/NFAT1 inhibitor
MA242 is a dual inhibitor of murine double minute 2 (MDM2) and nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy.
HSP90-calcineurin-NFAT inhibitor
YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.
Calcineurin-NFAT inhibitor
INCA-6 is a potent and selective inhibitor of calcineurin-NFAT (Nuclear Factor of Activated T cells) signaling.
NFAT Inhibitor, selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT).
1 publications
Jingwen Liu, .et al. , Cell Mol Gastroenterol Hepatol , 2021, Jul 1;S2352-345X(21)00135-1 PMID: 34217895
KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM.
