Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Nanaomycin E is a potent antibiotic primarily targeting Gram-positive bacteria and fungi. This compound exhibits significant antimicrobial activity, making it valuable for research into bacterial and fungal infections. Its mechanism of action and efficacy contribute to studies related to antibiotic resistance and the development of new antimicrobial agents. -
Phytotoxic Metabolite
Alternaric acid is a phytotoxic metabolite that functions as a host-specific toxin produced by certain plant fungi. This compound enhances the phosphorylation of His-tagged cytosolic kinase RiCDPK2 in the presence of Ca2+ and Mg2+, highlighting its role in plant-fungal interactions. Alternaric acid is useful for studying plant defense mechanisms and signaling pathways in response to pathogenic attacks. -
Anthraquinone Derivative
Neobulgarone B is an anthraquinone derivative derived from the ascomycete fungus Neobulgaria pura HA A07-97. This compound is primarily known for its ability to inhibit the formation of appressoria in the plant pathogenic fungus Magnaporthe grisea, which is crucial for understanding fungal infection processes. Additionally, Neobulgarone B exhibits weak cytotoxicity while showing no significant antifungal, antibacterial, or phytotoxic effects, making it a valuable tool for research in fungal biology and plant pathology. -
Antifungal Agent
Isoconazole is a broad-spectrum antifungal agent primarily targeting Candida albicans. This azole compound exhibits significant antimicrobial activity and is valuable in research focused on dermatomycoses and fungal infections. Its effectiveness makes it suitable for various studies involving the treatment and understanding of superficial fungal diseases. -
Intermediate of Antifungal Agents
Echinocandin B nucleus is a key intermediate in the synthesis of semi-synthetic antifungal agents, generated through the enzymatic action of Echinocandin B deacylase. This compound is integral for the development of antifungal therapeutics, offering a scaffold for modifications that enhance potency and activity against fungal pathogens. Research applications include studying the structure-activity relationship and optimizing antifungal efficacy. -
Antibiotic
(Rac)-Amorolfine hydrochloride is a racemic form of the antifungal agent Amorolfine, which primarily targets ergosterol biosynthesis. This compound exhibits potent antibacterial activity and has shown promise in research applications related to treating onychomycosis caused by Neoscytalidium dimidiatum. Its ability to inhibit fungal growth makes it a valuable tool in studies focused on antifungal mechanisms and developing novel therapeutic strategies. -
Fungus Metabolite
Cladospirone bisepoxide is a fungal metabolite known for its selective antibiotic properties against various bacteria and fungi. This compound exhibits notable activity in inhibiting the germination of Lepidium sativum at low concentrations, making it relevant for studies in microbial resistance and plant growth regulation. Its unique mechanism provides valuable insights into fungal biology and potential applications in agricultural and ecological research. -
Antifungal Agent
27-O-Demethylrapamycin, a derivative of Rapamycin, functions primarily as an antifungal agent. It demonstrates significant inhibitory activity against Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum. This compound is valuable for research applications focusing on antifungal mechanisms and the exploration of novel therapeutic strategies against fungal infections. -
Antifungal Agent
Cytochalasin R is a cytochalasin analogue derived from the endophytic fungus Phomopsis sp. xz-18. This compound exhibits notable antifungal activity, making it a valuable tool for researchers studying fungal infections and developing antifungal therapies. Its mechanism of action and efficacy highlight its potential applications in both basic and applied microbiological research. -
Fungal Inhibitor
Etisazole is a potent antifungal agent primarily targeting fungal infections. It exhibits significant antifungal activity against various dermatophytes and yeast species, making it valuable in studying skin-related fungal infections. Its skin sensitizing properties also provide insight into dermal reactions and safety assessments for antifungal therapies. This compound is applicable in both in vitro and in vivo research settings to explore antifungal efficacy and skin interaction mechanisms. -
Antifungal Agent
Diamthazole is an antifungal agent that targets fungal infections by inhibiting cell wall synthesis and disrupting cellular processes. It demonstrates significant activity against a variety of pathogenic fungi, making it a valuable tool for studying fungal biology and developing antifungal therapies. Researchers can utilize Diamthazole in the investigation of antifungal resistance mechanisms and in the evaluation of new treatment strategies for fungal infections. -
Fungicide
Furametpyr is a fungicide that targets fungal pathogens to effectively control rice sheath blight. It demonstrates a broad spectrum of metabolic activity in rats, mediated by recombinant human cytochrome P450 enzymes. This compound is utilized in agricultural research to study mechanisms of fungal resistance and to optimize crop protection strategies. -
Antifungal Compound
Rimocidin is a polyene macrolide that exhibits potent antifungal activity. It demonstrates broad-spectrum effectiveness against various plant-pathogenic fungi, making it a valuable tool in agricultural research and plant protection studies. Its mechanism of action involves disrupting fungal cell membrane integrity, providing insights into antifungal strategies and potential applications in crop management. -
Fungal
Aspergillin PZ is a novel isoindole-alkaloid derived from Aspergillus awamori, targeting fungal pathogens. This compound exhibits significant biological activity by inducing moderate deformation of conidia in Penicillium oryzae. Aspergillin PZ is valuable for research applications focusing on fungal biology and the mechanisms of fungal morphology alteration. -
Fungal Inhibitor
Demethoxypiplartine is an amide alkaloid derived from Piper flaviflorum and Piper sarmentosum, exhibiting potent antifungal activity. It demonstrates efficacy against Cryptococcus neoformans, with an IC50 value of 18.1 μg/mL. This compound is valuable for researchers investigating antifungal mechanisms and developing therapeutic strategies for fungal infections. -
Antibiotic Peptide
CRAMP-18 (mouse) is an antibiotic peptide that exhibits selective antimicrobial activity without hemolytic properties. It demonstrates effective inhibitory action against Gram-negative bacteria, including Salmonella typhimurium and Pseudomonas aeruginosa. This peptide serves as a valuable tool for research applications in antifungal, antibacterial, and antitumor studies. -
Volatile Compound
3,5-Dimethyl-4-octanone is a volatile compound primarily known for its occurrence in Lippia alba. This compound exhibits potential antifungal activity, making it a valuable candidate for studies related to fungal infections. Its unique properties support research in the development of antifungal agents and characterization of plant-derived substances. -
Anti-fungal Agent
Nifuroxime is an anti-fungal agent that operates through the inhibition of fungal growth by disrupting nucleic acid synthesis. It exhibits potent activity against various fungal pathogens, making it a valuable reagent in the study of fungal infections and the development of antifungal therapies. This compound is useful for researchers investigating the mechanisms of action and resistance in fungal biology. -
Antifungal Agent
Picarbutrazox is a potent antifungal agent targeting various fungal pathogens. It is effective against Pythium and Phytophthora, making it suitable for agricultural applications, particularly in the cultivation of corn and soybean. Picarbutrazox serves to enhance crop protection and promote healthy plant development by mitigating fungal infections. -
Chitin synthase Inhibitor
Chitin Synthase Inhibitor 1 is a potent and selective inhibitor of chitin synthase (CHS) with an IC50 value of 0.12 mM. This compound exhibits significant antifungal activity against drug-resistant fungal variants, making it a valuable tool for research in antifungal drug development and fungal pathogenesis studies. Its mechanism of action provides insight into chitin metabolism and its role in fungal cell wall synthesis. -
Fungicide
Propamocarb hydrochloride is a systemic fungicide that targets various fungal pathogens. It is primarily utilized in agricultural settings to protect crops such as cucumbers and tomatoes from disease, thereby enhancing plant health and yield. Its mechanism of action involves inhibiting fungal growth, making it a valuable tool in crop management and plant protection research. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 9 is a selective inhibitor of chitin synthase (CHS), which plays a critical role in fungal cell wall synthesis. This compound exhibits broad-spectrum antifungal activity, making it suitable for investigating fungal infections. It serves as a valuable tool in research aimed at understanding the mechanisms of fungal pathogenesis and evaluating potential therapeutic strategies against fungal diseases. -
Antibacterial Agent, Antifungal Agent, Cell Proliferation Inhibitor
Deacetylnomilin, derived from Citrus reticulata, exhibits significant antibacterial and antifungal properties. Additionally, it serves as a potent inhibitor of cell proliferation, demonstrating an IC50 value of 0.005 µg/mL against estrogen receptor-positive (ER+) cells. This compound is valuable for research in microbiological studies and cancer biology. -
Antifungal Agent
Voriconazole camphorsulfonate is a second-generation broad-spectrum triazole antifungal agent that primarily targets fungal ergosterol biosynthesis. It exerts its antifungal activity by inhibiting 14-α-lanosterol demethylation, a process that is mediated by fungal cytochrome P450 enzymes. This compound is widely used in research applications to study fungal infections and evaluate therapeutic strategies against a range of pathogenic fungi. -
Succinate Dehydrogenase Inhibitor
Siccanin is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 0.9 μM with selective activity across species. In addition to its role as an SDH inhibitor, Siccanin demonstrates antimicrobial properties against pathogenic fungi. This compound is valuable for research applications focused on metabolic processes and the treatment of fungal infections. -
Antibacterial Agent
Rugulosin is a crystalline compound derived from Penicillium rugulosum, exhibiting potent antibacterial properties. This agent demonstrates selective activity against a variety of bacterial strains while also displaying moderate antifungal effects. Its unique biological activity makes Rugulosin a valuable tool for research in microbial biology and the development of new antibacterial therapies. -
Antifungal Agent
Antibiofilm agent-12 is a carbazate derivative with a primary mechanism as an antifungal agent targeting Candida auris. It exhibits significant antifungal activity, demonstrated by a minimum inhibitory concentration (MIC90) of 237.9 μM, and functions by disrupting drug efflux pump activity and promoting ergosterol depletion. This effectively hinders biofilm formation and decreases the metabolic flexibility of Candida auris. Furthermore, Antibiofilm agent-12 has shown efficacy in a C. elegans model infected with Candida auris, highlighting its potential for addressing fungal infections and biofilm-related complications. -
Bassiatin Enantiomer
(3R,6S)-Bassiatin is an enantiomer of the fungal metabolite Bassiatin, known for its ability to inhibit ATPase activity in erythrocyte membranes, leading to cell lysis. This compound's mechanism suggests that its effects are linked to disruptions in membrane integrity. (3R,6S)-Bassiatin is useful in studies exploring erythrocyte physiology and the biochemical pathways involved in cell membrane interactions and integrity. -
Antifungal Agent
9-OxoOTrE (9-KOTrE) functions as an antifungal agent targeting multiple fungal species, including Botrytis cinerea, Cladosporium herbarum, Phytophthora infestans, and Phytophthora parasitica. Its electrophilic mechanism enables effective disruption of fungal cellular processes. This compound is valuable in research aimed at understanding fungal pathogenicity and developing potential therapeutic strategies against fungal infections. -
Succinate Dehydrogenase Inhibitor
SDH-IN-7 is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 26 nM against porcine SDH. This compound demonstrates significant fungicidal activity, making it a valuable tool for research applications focused on mitochondrial metabolism and fungal pathogenicity. Its inhibitory effect on SDH suggests potential implications in cancer research and metabolic studies. -
Fungicide
Vinclozolin is a non-systemic dicarboximide fungicide that primarily targets fungal spores, effectively inhibiting germination and controlling fungal growth in various crops, including fruits and vegetables. Additionally, Vinclozolin functions as an androgen receptor antagonist, exerting anti-androgenic effects via its metabolites. Studies have indicated its reproductive toxicity in rat models and its potential anti-tumor properties, making it valuable for research in toxicology and cancer biology. -
Fungal Inhibitor
NSC-670224 is a potent fungal inhibitor that demonstrates toxicity to Saccharomyces cerevisiae with an LC50 of 3.2 μM. This compound is useful for studying the effects of fungal inhibition and can serve as a vital tool in antifungal research and the exploration of yeast biology. -
Phytotoxic Metabolite
Altiloxin A is a drimane-type sesquiterpenoid derived from fungal metabolism, exhibiting significant phytotoxic activity. It has been reported to inhibit the growth of lettuce seedlings, making it a valuable tool for studying plant-fungal interactions and herbicide mechanisms. This compound is useful in research applications aimed at understanding phytotoxic effects and their implications in agriculture. -
Fungicide
Propamocarb is a systemic fungicide that targets various fungal pathogens in agricultural settings. It is effective in the control of diseases affecting crops such as cucumbers and tomatoes, thereby enhancing plant health and yield. Its broad-spectrum efficacy makes it a valuable tool for researchers studying plant disease management and fungicide resistance. -
Anti-Fungal Agent
Phoslactomycin C is an anti-fungal agent that exhibits potent activity against various fungal pathogens. While it demonstrates a weak effect against Gram-positive bacteria, its primary efficacy lies in combating fungal infections. This compound is valuable for research focusing on antifungal mechanisms and the development of new therapeutic strategies against fungal diseases. -
Antifungal Agent
(25RS)-Schidigera-saponin E1 is a steroidal saponin known for its antifungal properties, isolated from the stems of Yucca schidigera. It demonstrates weak antifungal activity by compromising microbial cell membrane integrity, with a minimum inhibitory concentration (MIC) of ≥100 μg/mL against various food spoilage yeasts. This compound is suitable for applications in food preservation, aiding in the extension of shelf life for products such as cooked rice, beans, and fermented condiments. -
Cyclic AMP Phosphodiesterase Inhibitor, Antifungal Agent
Sequosempervirin B is a norlignan that acts as an inhibitor of cyclic AMP phosphodiesterase, demonstrating notable antifungal activity. Isolated from the branches and leaves of Sequoia sempervirens, this compound is significant in the study of fungal infections and the modulation of intracellular signaling pathways. Its ability to inhibit cyclic AMP degradation positions it as a valuable tool for research in both pharmacology and mycology. -
Antifungal Agent
Antifungal Agent 39 (Compound 9h) is a broad-spectrum antifungal compound that targets fungal cell membranes and disrupts their integrity. This agent exhibits significant inhibitory activity against various pathogenic fungi, making it suitable for applications in antifungal drug discovery and research. Its efficacy in combating fungal infections positions it as a valuable tool in studying antifungal resistance and therapeutics. -
Antifungal Agent
Topazolin is a flavone that exhibits antifungal activity, primarily targeting Cladosporium herbarum AHU 9262. This compound demonstrates weak fungi-toxic properties, making it a valuable tool for studying fungal pathogenesis and evaluating potential antifungal therapies in research applications. -
Antifungal Agent
Aszonapyrone A is a secondary metabolite derived from Aspergillus zonatus, functioning primarily as an antifungal agent. This compound exhibits significant antifungal activity, making it a valuable tool for studying fungal infections and their treatments. Its diverse biological properties support research in mycology and infectious disease, providing insights into antifungal mechanisms and potential therapeutic applications. -
Antifungal Agent
4-O-Methylsappanol is a natural isoflavonoid recognized for its antifungal properties. It exhibits significant activity against Beauveria bassiana, providing potential for applications in fungal research. Notably, 4-O-Methylsappanol has been shown to inhibit melanin synthesis in HMV-II cells with an EC50 of 4.6 μM, making it a valuable tool for studies involving melanin-related processes. -
Antifungal Agent
Toonaciliatin M is a pmaradiene-type diterpenoid derived from Toona ciliate, exhibiting potent antifungal activity primarily against Trichophyton rubrum. With a minimum inhibitory concentration (MIC) of 12.5 µg/mL, it is a valuable compound for investigating antifungal mechanisms and exploring potential therapeutic applications in fungal infections. Researchers can utilize Toonaciliatin M to better understand its efficacy and broader applications in antifungal drug development. -
Chitin Deacetylase Inhibitor
CDA-IN-2 is a potent inhibitor of chitin deacetylase (CDA), effectively targeting the enzymes PxCDA1 and PxCDA2 in the pathogen P. xanthii. At a concentration of 100 μM, CDA-IN-2 demonstrates significant antifungal activity, achieving inhibition rates of 83.7% and 74.5%, respectively. This compound is valuable for research into managing agricultural fungal diseases, particularly against resistant strains of powdery mildew and Botrytis cinerea. -
Antifungal Agent
Sulconazole is a potent antifungal agent belonging to the imidazole class, primarily known for its ability to inhibit fungal growth. It exerts its effects by blocking the NF-κB/IL-8 signaling pathway, which is implicated in cancer stem cell formation and tumor progression. Additionally, Sulconazole shows potential for applications in breast cancer research, highlighting its dual role as both an antifungal and an anti-tumor compound. -
Fungicide
Zarilamid is a fungicide targeting Oomycete fungi, demonstrated to inhibit nuclear division in germinating zoospore cysts of Phytophthora capsici. This compound disrupts microtubule cytoskeleton integrity, leading to impaired mitosis and abnormal swelling of root tips in tobacco. Zarilamid is valuable for research on fungal growth inhibition and cellular mechanisms associated with Oomycete pathogens. -
Fungal
Phlebiakauranol aldehyde is a potent antifungal and cytotoxic metabolite, primarily targeting fungal pathogens. It demonstrates significant antibacterial and cytotoxic effects against various plant pathogens, attributed to its aldehyde group and multiple hydroxyl groups. This compound serves as a valuable tool for research in fungal biology and antimicrobial activity, providing insight into its mechanisms of action and potential applications in plant protection. The related acetic acid derivatives exhibit only minimal biological activities, highlighting the unique efficacy of Phlebiakauranol aldehyde. -
1,3-β-glucan Synthase Inhibitor
Arborcandin D is a potent inhibitor of 1,3-β-glucan synthase, functioning as an effective antifungal antibiotic. It demonstrates notable inhibitory activity with IC50 values of 3 μg/mL against Candida albicans and 0.35 μg/mL against Aspergillus fumigatus. Furthermore, Arborcandin D exhibits a minimal inhibitory concentration (MIC) of 4 μg/mL against the Candida genus, making it a valuable tool for research on fungal infections and treatment development. -
Antifungal Agent
Sporothriolide, a potent antifungal agent derived from the metabolite of Nodulisporium sp. A21, exhibits strong inhibitory effects against various fungal pathogens, specifically R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. Additionally, Sporothriolide effectively inhibits the conidium germination of Magnaporthe oryzae, both in vitro and in vivo, making it a valuable tool for research in antifungal activity and plant disease management. -
Antifungal Agent
13-Epimanool is a potent antifungal agent derived from the bark of the Taiwan hemlock. This compound exhibits significant inhibitory activity against various fungal pathogens, making it a valuable tool for research into antifungal treatments and mechanisms. Its unique properties facilitate investigations into the biosynthetic pathways of natural products and the development of novel antifungal therapies. -
Secondary Metabolite
Strevertene A is a pentaene macrolide classified as a secondary metabolite with notable antibiotic properties. This compound exhibits potent antifungal activity, effectively inhibiting the mycelial growth of various phytopathogenic fungi, including Alternaria mali, Aspergillus oryzae, and Cylindrocarpon destructans, with IC50 values ranging from 4 to 16 μg/mL. Additionally, Strevertene A demonstrates the ability to significantly mitigate the development of Fusarium wilt in tomato plants, making it a valuable reagent for agricultural and fungal research applications.
