Catalog No.
Product Name
Application
Product Information
Citations
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Pah Inhibitor
Phosphatase-IN-1 is a phosphatidate phosphatase (Pah) inhibitor that selectively targets MoPah1 with an affinity constant of 19.8 μM. This compound demonstrates significant antifungal activity, effectively inhibiting the growth of various plant pathogens. Importantly, Phosphatase-IN-1 exhibits low toxicity towards rice seedlings and wheat heads, making it a valuable tool for research in plant pathology and agricultural applications. -
Antifungal Agent
Antifungal Agent 35 is a potent antifungal compound that enhances the activity of Fluconazole against Candida albicans. This compound functions by inhibiting key fungal pathways, thereby improving therapeutic efficacy. It is suitable for research applications focused on improving antifungal treatments and understanding drug interactions in fungal pathogens. -
Antifungal Agent
Antifungal Agent 58 (Compound A21) is a potent antifungal compound specifically targeting Fluconazole-resistant Candida albicans strains. Demonstrating superior efficacy compared to Miconazole, it exhibits minimal inhibitory concentration (MIC) values ranging from 0.06 to 8 μg/mL. This compound is promising for research applications focused on developing new treatments for antifungal resistance and studying fungal biology. -
Antibiotic
Alamethicin F 50 is an antibiotic that functions as a membrane-active peptide. It exhibits significant antifungal and antibacterial activity by disrupting microbial cell membrane integrity, leading to cellular content leakage and cell death. Additionally, Alamethicin F 50 reduces water surface tension, making it suitable for applications as a surfactant or detergent in various research settings. -
Antifungal Agent
γ-Thujaplicin is a naturally occurring compound with antifungal properties derived from the wood of Thujopsis dolabrata. It demonstrates significant cytotoxic effects against human stomach cancer cell lines, including KATO-III and Ehrlich’s ascites carcinoma, while also exhibiting broad-spectrum antifungal activity against wood-rotting fungi. Additionally, γ-Thujaplicin possesses insecticidal effects on harmful insect species. This compound is valuable for research in cancer biology, infectious disease studies, and integrated pest management strategies. -
Antifungal Agent
Antifungal Agent 94, a flavonoid derivative, primarily targets various fungal pathogens. It demonstrates significant antifungal activity with an EC50 of 0.28 μM and a half-maximal effective concentration of 0.46 μg/mL specifically against Rhizoctonia solani. This compound is useful for research in fungal biology and the development of antifungal therapies. -
Anti-Fungal Agent
5-Geranoxy-7-methoxycoumarin is a coumarin derivative exhibiting significant antifungal activity. This compound has demonstrated the ability to induce apoptosis in fungal cells, making it a valuable tool for research into antifungal therapies. Its unique structure and biological properties make it suitable for further investigation in the study of fungal infections and related applications. -
Antiproliferative Agent
Antiproliferative Agent-33 is a potent antiproliferative compound known for its ability to inhibit cell proliferation, particularly in MDA-MB-231 breast cancer cells with an IC50 value of 16.38 μM. Additionally, this compound exhibits antifungal and antibacterial properties, effectively inhibiting growth of gram-negative bacteria and demonstrating a minimum inhibitory concentration (MIC) of 8 μg/mL against Enterococcus faecalis. It is suitable for research applications focused on cancer biology, microbiology, and drug development. -
Antifungal Agent
Hemigossypol is a sesquiterpene natural product derived from Gossypium barbadense, primarily recognized for its antifungal properties. This compound exhibits notable efficacy against various fungal strains, making it valuable for research applications focused on antifungal drug development and the study of fungal pathogenesis. Hemigossypol serves as a useful tool in understanding the mechanisms of fungal resistance and may contribute to the advancement of therapeutic strategies in mycology. -
Antibiotic
Rodaplutin is a ribosomal peptide antibiotic that targets bacterial protein synthesis. It exhibits significant anti-inflammatory effects by inhibiting the release of inflammatory mediators in various animal models. This compound is of particular interest for research applications related to infections and inflammatory diseases, making it a valuable tool for studying potential therapeutic interventions. -
Fungicidal Agent
FM-678 is a potent fungicidal agent designed to target and inhibit fungal growth. It exhibits exceptional efficacy against Phakopsora pachyrhizi, with an effective concentration (EC50) of 0.14 mg/L. This compound is valuable for research applications involving plant pathology and the development of antifungal strategies. -
Antibiotic
Ossamycin is a macrolide antibiotic primarily targeting bacterial and fungal infections. It exhibits significant antifungal activity while demonstrating weaker effects against Gram-positive bacteria. In cellular assays, Ossamycin effectively inhibits the proliferation of various cancer cell lines, including L cells, Epstein-Barr ascites cancer cells, KB cells, sarcoma-180 cells, L-1210 cells, and HeLa cells, with IC50 values ranging from 0.003 to 0.008 µg/mL. This makes Ossamycin a valuable tool for research applications in microbiology and oncology. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 13 is a non-competitive inhibitor specifically targeting chitin synthase, demonstrating an IC50 value of 106.7 μM. This compound exhibits broad-spectrum antifungal activity, making it a valuable tool for research in fungal biology and the development of antifungal therapies. Its mechanism of action can provide insights into chitin biosynthesis and contribute to the understanding of fungal cell wall integrity. -
Antifungal Agent
Effusanin B is a diterpenoid compound isolated from Rabdosia effusa (Maxim.) Hara, exhibiting potent antifungal properties. This compound targets fungal cell membrane integrity, making it a valuable tool for researching antifungal mechanisms and developing new therapeutic strategies against fungal infections. Its unique structure and biological activity provide opportunities for exploring applications in pharmacology and mycology. -
Fungal
Janthitrem F is a metabolite derived from the tremorigenic fungus Penicillium, primarily targeting fungal pathways. This compound is associated with inducing neurological effects in mammals and is investigated for its potential role in ryegrass spurt disease pathology. Janthitrem F serves as a valuable tool in studying fungal metabolites and their impacts on animal health. -
Antifungal Agent
(4S)-(+)-Ascochin serves as an antifungal agent primarily targeting Microbotryum violaceum, Phytophthora infestans, and Septoria tritici. Additionally, it demonstrates antialgal activity against Chlorella fusca. This compound is valuable for research in plant pathology and the study of fungal-algal interactions. -
antifungal agent
Croconazole is an antifungal agent that features imidazole rings with an aryl vinyl substituent at the N-1 position. This compound exhibits potent antifungal activity, making it useful for research on fungal infections. Additionally, Croconazole can be utilized for the identification and quantitative analysis of major metabolites in rat urine and bile, aiding in pharmacokinetic studies. -
Antifungal Drug
Rabdoserrin A is a diterpenoid known for its antifungal properties. This compound demonstrates significant activity against various fungal pathogens, making it a valuable tool in the study of antifungal mechanisms and the development of antifungal therapies. Researchers can utilize Rabdoserrin A in assays aimed at understanding fungal resistance and evaluating the efficacy of novel antifungal agents. -
Fungal Inhibitor
Bac2A TFA is an antimicrobial peptide that acts as a potent inhibitor of fungal pathogens. This linear variant of bactenecin exhibits significant antifungal activity, making it suitable for research applications focused on fungal infections and immunomodulation studies. Its unique properties offer potential insights into host-pathogen interactions and the development of novel therapeutic strategies against fungal diseases. -
Antifungal Agent
Antifungal agent 32 primarily targets Candida albicans, exhibiting potent antifungal activity. This compound effectively inhibits filamentation and biofilm formation, preventing morphological switching and adherence to epithelial cells. Antifungal agent 32 serves as a valuable tool for research focused on Candida albicans infections and related antifungal treatments. -
Antifungal Agent
(+)–Pinoresinol diacetate is an antifungal agent that targets fungal cells by disrupting membrane integrity. Isolated from Sambucus williamsii, it exhibits significant antifungal activity, making it a valuable compound for studying fungal infections. This reagent is applicable in research focused on developing novel antifungal therapies and understanding antifungal mechanisms. -
Antifungal Antibiotic
Echinocandin B is an antifungal antibiotic that targets the synthesis of β-glucan in the fungal cell wall. It exhibits potent activity against a variety of pathogenic fungi, making it a valuable reagent in antifungal research. This compound is particularly useful for studying fungal infections and evaluating the efficacy of new antifungal therapies. -
Antifungal Agent
Ys-II is a spirostanol glycoside derived from the stem of Yucca elephantipes, exhibiting significant antifungal activity. It demonstrates inhibitory effects against Candida albicans and Cryptococcus neoformans, with IC50 values of 5 μg/mL and 6 μg/mL, respectively. This compound is useful in research applications focused on fungal infections and the exploration of potential antifungal therapies. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 5 specifically targets chitin synthase, demonstrating an IC50 value of 0.14 mM. This compound exhibits broad-spectrum antifungal activity in vitro, effectively inhibiting the growth of Candida albicans, Aspergillus flavus, Aspergillus fumigatus, and Cryptococcus neoformans. Chitin Synthase Inhibitor 5 is valuable for research focused on fungal pathogenesis and potential therapeutic strategies against fungal infections. -
Fungal Inhibitor
Deoxyviolacein is a bacterial metabolite that acts as a potent fungal inhibitor. It demonstrates significant antifungal activity against Rhizoctonia solani at a concentration of 2 mg/mL. Additionally, Deoxyviolacein exhibits antibacterial properties against Gram-positive bacteria, such as Staphylococcus aureus, Bacillus subtilis, and Bacillus megaterium, with effective inhibition observed at 125 μg/mL. This compound has potential applications in cancer research, particularly in inhibiting the proliferation of hepatocellular carcinoma cells at concentrations ranging from 0.1 to 1 μM. -
Fungicide
Metalaxyl-M-d6 is a deuterium-labeled derivative of Metalaxyl-M, a selective inhibitor of fungal RNA polymerase. This compound exhibits potent fungicidal activity by obstructing the synthesis of fungal ribosomal RNA. In addition to its primary function as a fungicide, Metalaxyl-M-d6 is utilized in studies involving inflammation in hepatocytes and the regulation of tryptophan metabolism. Furthermore, it serves as a valuable reagent in ecotoxicology research. -
Antibiotic
6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound primarily acting as an antibiotic. It exhibits a broad range of biological activities including antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antituberculosis, antiparasitic, and antiviral effects. This compound is valuable for research in drug development, infectious disease studies, and the investigation of therapeutic pathways in various biological systems. -
Bacterial Metabolite
(–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid, with notable antibacterial and antifungal properties. It demonstrates activity against Gram-positive bacteria, including Bacillus subtilis, Kocuria rhizophila, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 4, 8, and 4 µg/mL, respectively. In contrast, it exhibits limited effectiveness against Gram-negative bacteria such as Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. Additionally, (–)-Mycousnine is effective against fungi, including Trichophyton mentagrophytes, Trichophyton rubrum, and Candida albicans, with MICs of 25, 25, and 100 µg/mL, respectively. This compound is suitable for research in antimicrobial drug development and fungal infection studies. -
Antifungal Agent
Eberconazole is a dichlorinated imidazole derivative that exerts its antifungal activity by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This compound demonstrates significant effectiveness against dermatophytes, making it a valuable tool for research in dermatophytosis and other fungal infections. Eberconazole's unique mechanism of action supports its application in studying antifungal therapies and resistance mechanisms in pathogenic fungi. -
Antifungal Agent
Antifungal agent 127 is an antifungal compound that targets a broad spectrum of fungal pathogens. It demonstrates potent inhibitory activity against Botrytis cinerea, Rhizoctonia solani, and various other fungal species. This compound is valuable in research applications aimed at understanding fungal infections and developing effective antifungal treatments. -
Antifungal Agent
Trianthenol is a tetraterpenoid compound that functions as an antifungal agent. It exhibits significant inhibitory activity against various fungal pathogens, making it a valuable tool for research in mycology and the development of antifungal therapies. Isolated from the whole plant of Trianthema portulacastrum, Trianthenol serves as a potential candidate for studies aimed at understanding fungal resistance mechanisms and exploring new antifungal treatments. -
Anthraquinone Fungicide
Dithianon is a broad-spectrum anthraquinone fungicide that exhibits strong adhesion to the surfaces of leaves and fruits. It effectively controls various fungal pathogens, including anthracnose caused by Colletotrichum spp. and Elsinoe ampelina, as well as mildew due to Plasmopara viticola and phomopsis infections in Phomopsis viticola. This compound is widely utilized in agricultural research to enhance crop protection and improve yield by mitigating fungal disease incidence in fruits and vegetables. -
Antifungal Agent
Antifungal Agent 27 primarily targets fungal pathogens exhibiting antifungal activity. This compound demonstrates moderate antibacterial effects against Methicillin-Resistant Staphylococcus aureus (MRSA) and weak antifungal activity against Candida albicans SS5314, with minimal inhibitory concentration (MIC) values of 8 μg/mL and 32 μg/mL, respectively. It is suitable for research applications focusing on the development of novel antifungal therapies and the study of resistance mechanisms in pathogenic microbes. -
Antifungal Agent
2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin with notable antifungal properties, primarily targeting fungal pathogens. Isolated from the root tissue of Sanguisorba minor, this compound demonstrates strong inhibition of spore germination in Botrytis cinerea, making it valuable for research into antifungal mechanisms and plant defense responses. Its biological activity supports investigations into natural compounds for enhancing plant resistance to fungal infections. -
Antibiotic
Tetranactin is an orally active antibiotic targeting Gram-positive bacteria and fungal pathogens. It demonstrates significant insecticidal properties and effectively inhibits the growth of various plant pathogenic fungi in vitro. Toxicity studies indicate a high safety margin, with an LD50 greater than 300 mg/kg for intraperitoneal injection in mice and greater than 15,000 mg/kg overall. This compound is valuable for research applications focusing on antibacterial and antifungal mechanisms. -
Antifungal And Antiviral
Verlamelin A is a macrocyclic depsipeptide known for its antifungal and antiviral properties. It exhibits significant antifungal activity against Aspergillus versicolor and Curvularia australiensis, alongside antiviral effects against HSV-1 with an IC50 of 16.7 μM. Isolated from the entomopathogenic fungus Lecanicillium sp., Verlamelin A serves as a valuable tool in antifungal and antiviral research applications. -
Fungal Inhibitor
Benzyl 2-hydroxy-6-methoxybenzoate acts as a potent fungal inhibitor, demonstrating significant antifungal activity with an IC50 of 25–26 μg/mL against various fungal strains. This compound is valuable in research focused on antifungal drug development and investigating fungal resistance mechanisms. Its efficacy makes it a promising candidate for further exploration in therapeutic applications against fungal infections. -
Antifungal Agent
Antifungal Agent 36 is a potent antifungal compound with a specific mechanism targeting Basidiomycetes. This reagent exhibits significant antifungal activity, making it suitable for research applications focused on fungal infections and related studies. It provides a valuable tool for investigating the efficacy of antifungal treatments in various biological systems. -
Antifungal Agent
Antifungal Agent 122 is a potent broad-spectrum antifungal compound, primarily targeting fungal phase transition and biofilm formation. This agent inhibits CYP3A4-M and CYP3A4-T enzyme activity with IC50 values of 2.11 µM and 4.53 µM, respectively. Notably, Antifungal Agent 122 demonstrates no cytotoxic effects, making it a valuable candidate for antifungal research applications. -
Antibacterial Drug
Antibacterial agent 129 is an oxetanyl-quinoline derivative that exhibits potent antibacterial activity targeting Pseudomonas mirabilis and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 31.25 μM and 31.5 μM, respectively. Additionally, it demonstrates significant antifungal activity against Aspergillus niger, also with an MIC of 31.25 μM. Notably, Antibacterial agent 129 displays excellent antimycobacterial properties, with an MIC of 57.73 μM against Mycobacterium tuberculosis H37Rv. This compound can be utilized in pharmaceutical research to explore new antibacterial and antifungal therapies. -
Antifungal Antibiotic
3'-O-Decarbamoylirumamycin is a 20-membered macrolide antibiotic that targets fungal infections, derived from Streptomyces subflavus subsp. Irumaensis. This compound exhibits significant antifungal activity against plant pathogenic fungi, including Piricularia oryzae and Sclerotinia cinerea. It is utilized in research focused on antifungal drug development and the study of fungal biology. -
Antifungal Agent
Plumieride is an antifungal agent that exhibits significant fungitoxicity against various dermatophytes. It demonstrates minimal cytotoxic activity, with an IC50 of 85 μg/mL against the P388 leukemia cell line. This compound is primarily utilized in studies focusing on antifungal efficacy and the evaluation of fungal pathogens. -
Antifungal Agent
Colutehydroquinone is an isoflavonoid primarily sourced from the root bark of Colutea arborescens. It demonstrates notable antifungal activity, making it a valuable reagent for research focused on fungal infections and related diseases. Its application in studying the mechanisms of antifungal action can contribute significantly to the development of new therapeutic strategies. -
Fungal Inhibitor
Antifungal agent 67 is an imidazole compound that targets fungal pathogens, demonstrating significant efficacy against Candida species. This agent exhibits a CC50 value of 33.6 μM in healthy neonatal rat cardiomyoblasts, indicating its potential impact on cellular viability. Antifungal agent 67 is suitable for research applications concerning antifungal mechanisms and the development of therapeutic strategies against fungal infections. -
1,3-β-glucan Synthase Inhibitor
Arborcandin C is a potent inhibitor of 1,3-β-glucan synthase, functioning as an antifungal antibiotic. It demonstrates strong biological activity with IC50 values of 0.15 μg/mL against Candida albicans and 0.015 μg/mL against Aspergillus fumigatus. Furthermore, Arborcandin C exhibits a minimum inhibitory concentration (MIC) of 1-2 μg/mL against various Candida species, making it valuable for research into antifungal mechanisms and treatments. -
Fungicidal Agent
Antifungal Agent 65 is a potent fungicidal agent targeting Fusarium oxysporum f.sp. cucumerinum. This compound demonstrates remarkable antifungal activity, making it suitable for various research applications in antifungal and antiviral studies. Its efficacy in combating specific fungal pathogens positions it as a valuable reagent for further exploration in agricultural and therapeutic research. -
Antifungal Agent
AEC5 is a lipopeptoid that exhibits antifungal activity specifically against Cryptococcus neoformans. It demonstrates a minimum inhibitory concentration (MIC) of 6.3 μg/mL without eliciting cytotoxic effects on human lung, liver, or red blood cells. This compound is suitable for research applications involving the study of antifungal mechanisms and the development of novel therapeutics targeting fungal infections. -
Anti-Fungal Agent
Enoxastrobin is an anti-fungal agent that targets various pathogenic fungi. It exhibits strong activity against Pyricularia oryzae and Botrytis cinerea, making it a valuable tool in agricultural research and crop protection studies. Its efficacy in inhibiting fungal growth supports investigations into disease management in agricultural systems. -
Antifungal Agent
SS-750 is an orally active triazole derivative that functions as an antifungal agent by binding to fungal cytochrome P450 enzymes. This compound exhibits potent antifungal activity against various Candida species, including C. parapsilosis, C. krusei, and C. glabrata, with MIC90 values of 0.25, 1, and 2 μg/mL, respectively. Additionally, SS-750 demonstrates efficacy in improving systemic and pulmonary infections caused by C. albicans. Its profile makes SS-750 a valuable reagent for research into antifungal therapies and resistance mechanisms. -
Antifungal Agent
Isopicropodophyllone is a natural compound derived from the leaves of Podophyllum hexandrum, functioning as a potent antifungal agent. It exhibits significant inhibitory effects on various fungal strains, making it valuable for research related to fungal infections and the development of antifungal therapies. Its effectiveness in disrupting fungal growth supports its potential applications in both medicinal chemistry and mycology studies.
