Catalog No.
Product Name
Application
Product Information
Citations
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SARS CoV-2 3CLpro Inhibitor
SARS-CoV-2 3CLpro-IN-4 is a potent inhibitor of the SARS-CoV-2 3CL protease, a critical enzyme for viral replication. This compound exhibits significant antiviral activity, making it relevant for research in COVID-19 therapeutics. Its broad-spectrum impact also extends to antibacterial and antifungal activities, aiding investigations into multi-faceted infectious disease mechanisms. -
Antifungal Agent
Cytosporone C is an antifungal metabolite derived from the fungus Diaporthe eucalyptorum, associated with Melia azedarach. This compound demonstrates potent antifungal activity against Alternaria solani, making it valuable for research in fungal pathogenesis and therapeutic development. Its efficacy in inhibiting fungal growth positions Cytosporone C as a promising candidate for studying antifungal mechanisms and potential treatments. -
Ras Inhibitor
Antifungal agent 46 is a potent Ras inhibitor that targets protein farnesyltransferase, effectively disrupting Ras signaling pathways. This compound demonstrates significant antifungal activity and holds potential for research applications focused on understanding Ras-related mechanisms in fungal infections. Studies may explore its utility in elucidating the role of Ras in cellular signaling and its implications in therapeutic developments. -
Antimicrobial
Monogalactosyl diglyceride is an antimicrobial compound that exhibits both antibacterial and antifungal activity in vitro. It is primarily utilized in research focused on understanding the mechanisms of microbial inhibition and the development of novel antimicrobial agents. Its ability to disrupt microbial cell membranes makes it a valuable tool in pharmaceutical and biomedical investigations. -
Fungal Inhibitor
Antibacterial agent 188 is a potent fungal inhibitor that targets dermatophyte activity. This compound demonstrates significant antifungal properties, making it suitable for research applications focused on fungal infections and dermatological studies. Its mechanism of action involves disrupting fungal cell processes, thereby inhibiting growth and proliferation. -
Fungal
Bivittoside A is a non-sulfated hexoside analog derived from the bovine sea cucumber, primarily targeting fungal pathogens. This compound exhibits significant antifungal activity, making it a valuable tool for research into fungal infections. Additionally, Bivittoside A shows potential for antitumor applications, highlighting its versatility in cancer research. -
Succinate Dehydrogenase Inhibitor
Harzianopyridone is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 80 nM. Isolated from the fungus Trichoderma harzianum, this compound demonstrates significant antifungal, antibacterial, and herbicidal properties. Harzianopyridone is valuable for research applications exploring metabolic modulation and the study of fungal and bacterial pathways. -
Bacterial
Fenticonazole is an imidazole derivative that targets bacterial and fungal organisms. It exhibits significant antibacterial and antifungal activity, making it a valuable compound for the study of mixed vaginitis. This reagent is useful in exploring the efficacy of treatments against infections caused by both bacteria and fungi. -
Gamma-Glutamyl Transferase Inhibitor
Gamma-Glutamyl Transferase-IN-1 is a potent inhibitor of gamma-glutamyl transferase, specifically designed to disrupt its enzymatic function. This β-carboline 1-hydrazide compound exhibits significant antifungal and antibacterial activities by promoting the accumulation of reactive oxygen species, leading to cell membrane disruption and alterations in histone acetylation. It serves as a valuable tool for research investigating the roles of gamma-glutamyl transferase in various biological processes and disease states. -
Antiproliferative/Antimicrobial Agent
Antiproliferative agent-18 is an anti-proliferative compound that exhibits significant effects in inhibiting cell growth. This agent also exhibits moderate antibacterial and antifungal properties, making it valuable for research in microbiological studies and cancer treatment. Its diverse biological activity positions it as a useful tool for scientists exploring cellular proliferation and antimicrobial mechanisms. -
Antifungal Agent/LOX-1 Inhibitor
Sclerotiorin is a reversible uncompetitive inhibitor of soybean lipoxygenase-1 (LOX-1), with an IC50 value of 4.2 μM. This compound exhibits significant antioxidant activity by scavenging free radicals (ED50: 0.12 μM) and inhibiting nonenzymatic lipid peroxidation. Additionally, Sclerotiorin demonstrates antifungal properties and the ability to inhibit platelet aggregation. It can be isolated from the fermented broth of Penicillium frequentans, making it a valuable reagent for research in antifungal mechanisms and oxidative stress studies. -
SDH Inhibitor
SDH-IN-18 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 8.70 mg/L. This compound demonstrates significant antifungal activity, disrupting the morphology and reproduction of fungi. It is particularly effective against Rhizoctonia solani and Sclerotinia sclerotiorum, with EC50 values of 0.48 mg/L and 1.4 mg/L, respectively. SDH-IN-18 can be utilized in research studying fungal pathology and SDH-related metabolic pathways. -
Antifungal Drug
Isobellidifolin is a xanthone that acts as a free radical scavenger and antioxidant. It exhibits significant antifungal activity, making it a valuable compound for research applications focused on fungal infections and oxidative stress. This compound may be useful for studying mechanisms of antifungal resistance and the development of novel antifungal therapies. -
Antifungal Agent
Antifungal agent 30 (compound A18) is a potent antifungal compound that targets cytochrome P450 51 (CYP51). It demonstrates significant antifungal activity against Candida albicans and Aspergillus fumigatus, with minimum inhibitory concentrations (MIC) of 0.03 and 0.5 μg/mL, respectively. This agent is particularly effective against fluconazole-resistant strains, making it a valuable tool for research in antifungal drug development and resistance mechanisms. The activity of Antifungal agent 30 is primarily attributed to its hydrogen and coordination bond interactions with CYP51. -
Depsidone
Mollicellin K is a depsidone derived from the fungus Chaetomium brasiliense, exhibiting significant antimicrobial activity. It demonstrates potent activity against Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) of 12.5 μM, and strong antimalarial effects against Plasmodium falciparum (IC50 = 1.2 μM). Additionally, Mollicellin K displays antifungal properties against Candida albicans (IC50 = 1.2 μM) and cytotoxic effects against various cancer cell lines, including KB (IC50 = 1.9 μM) and BC1 (IC50 = 6.8 μM). This compound is of interest in research involving infectious diseases and cancer therapeutics. -
Anti-Cryptococcus Agent
P163-0892 is a potent anti-Cryptococcus agent that selectively targets Cryptococcus species. This compound exhibits significant antifungal activity, making it a valuable tool for research into Cryptococcus infections. Additionally, P163-0892 is predicted to demonstrate moderate blood-brain barrier (BBB) penetration, enhancing its potential applications in neurological studies related to cryptococcal diseases. -
Antifungal Agent
Pterolactam is an antifungal agent derived from Chrysanthemum coronarium L. It has demonstrated biological activity against various fungal strains and exhibits cytotoxic properties. Pterolactam and its analogues, including Mannich bases of amide, are useful for research applications aimed at understanding fungal infections and exploring potential therapeutic options in mycology. -
Antifungal Agent
Lyoniside is a lignan glycoside known for its potent antifungal properties. It effectively inhibits the mycelial growth of the fungi Fusarium oxysporum and Mucor hiemalis at a concentration of 50 μg/mL, achieving inhibition rates of 78% and 80%, respectively. Additionally, Lyoniside demonstrates antioxidant activity, with an IC50 value of 23 μg/mL in the DPPH assay, making it a valuable compound for research in antifungal development and antioxidant studies. -
Pdr1-KIX Inhibitor
Antifungal agent 72 is a selective Pdr1-KIX inhibitor that effectively suppresses efflux pump function and down-regulates resistance-related genes through disruption of the Pdr1-KIX interaction, with a Ki value of 11.7 μM. This compound demonstrates significant antifungal activity against Fluconazole-resistant strains, exhibiting a minimum inhibitory concentration (MIC) of 63 ng/mL and showing synergistic effects when used in combination with Fluconazole. Antifungal agent 72 is particularly valuable for research focused on C. glabrata infections and the development of novel antifungal strategies. -
Fungal
Janthitrem G is a fungal metabolite derived from Penicillium species, primarily acting as a potent inhibitor of fungal growth. This compound exhibits significant antifungal activity, making it valuable for research in mycology and the development of antifungal therapies. Its unique properties can aid in understanding fungal biology and resistance mechanisms. -
Anti-Plant Virus/Fungal Agent
TMV-IN-5 is an anti-plant virus and fungal agent that targets the tobacco mosaic virus (TMV) coat protein (CP). This compound inhibits viral assembly, making it a valuable tool in research aimed at developing effective pesticides for viral and fungal infections in plants. Its application can facilitate studies on plant virology and contribute to advancements in agricultural biotechnology. -
Fungal Inhibitor
Alteconazole is an azole derivative that acts as a potent antifungal agent. It exerts its action by inhibiting the enzyme lanosterol demethylase, which is essential for ergosterol synthesis in fungal membranes. This compound is valuable for research in the study of fungal pathogens and the development of antifungal therapies. Its mechanism of action makes it suitable for investigations into cellular responses to fungal infections and resistance mechanisms. -
PLA2 Inhibitor
Plipastatin B1 is a lipopeptide antibiotic that acts as an inhibitor of phospholipase A2 (PLA2). This compound exhibits antifungal activity, making it a valuable tool in investigating fungal pathogenesis and potential therapeutic interventions. It is applicable in research focusing on the modulation of PLA2-related pathways and the development of antifungal drugs. -
Fungal
Dendryphiellin D is a fungal-derived compound isolated from Septoria rudbeckiae, a plant pathogenic fungus from the halophyte Karelinia caspia. This compound is known to significantly inhibit the production of nitric oxide (NO), making it a valuable reagent for studies investigating fungal pathogenicity and host defense mechanisms. Research applications may include exploring its role in plant-microbe interactions and assessing its potential as a lead for antifungal drug development. -
SDH Inhibitor
Succinate dehydrogenase-IN-1 is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 0.94 μM and a KD of 22.4 μM. This compound demonstrates significant antifungal activity against various pathogens, including Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC50 values of 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively. Succinate dehydrogenase-IN-1 can be utilized in studies focusing on fungal infections and metabolic pathways involving SDH inhibition. -
Fungal Inhibitor
Antifungal Agent 120 is a potent fungal inhibitor targeting S. dermatitidis, a pathogenic fungus associated with skin infections. This reagent demonstrates significant antifungal activity and serves as a valuable tool for researchers studying fungal biology and therapeutic interventions. Further investigation may reveal efficacy against additional fungal species, expanding its potential applications in mycology research. -
Secondary Metabolite
Sporminarin A is a polyketide secondary metabolite derived from Sporormiella minimoides, demonstrating notable antifungal activity against Aspergillus flavus with a minimum inhibitory concentration (MIC50) of 25 μg/mL. Additionally, Sporminarin A exhibits antibacterial properties against Staphylococcus aureus (ATCC 29213) and antifungal effects against Candida albicans (ATCC 14053). This compound is valuable for research applications focused on microbial resistance and the development of novel antimicrobial agents. -
Polysaccharide Copolymer
L-Diguluronic acid is a linear polysaccharide copolymer consisting of two L-guluronic acid units, serving as a precursor for alginate formation. Alginate, an unbranched polyanionic polysaccharide, is utilized in various research applications, particularly in the delivery of antifungal agents. Its unique structural properties facilitate its use in drug delivery systems and biomaterials development. -
Antifungal Agent
Schidegera-saponin A1 is a spirostanol-type monosaccharide chain saponin recognized for its antifungal properties. Isolated from the stems of Yucca schidigera, it demonstrates significant inhibitory activity against food spoilage and film-forming yeasts, with a minimum inhibitory concentration (MIC) of 3.13 μg/mL against Saccharomyces cerevisiae and 6.25 μg/mL against Candida albicans. This compound is utilized in research applications aimed at studying yeast growth inhibition and food preservation strategies. -
Methoxycarbanilate Fungicide
Triclopyricarb is a methoxycarbanilate fungicide that exerts its activity by inhibiting mycelial growth in various fungal pathogens. With EC50 values ranging from 0.006 µg/mL to 0.047 µg/mL, it demonstrates potent efficacy in controlling crop diseases. This compound is primarily utilized in agricultural research for the study of fungal resistance and the development of disease management strategies. -
Antifungal Agent
Venturicidin B is a macrolide antibiotic derived from Streptomyces sp. and functions as a potent inhibitor of the mitochondrial F0-ATP synthase complex. This compound exhibits significant antifungal activity, making it useful in the research of fungal infections and mitochondrial function. Its mechanism of action provides insights into bioenergetics and the development of antifungal therapies. -
Antifungal Agent
Antifungal Agent 56 (Compound A09) is a potent antifungal agent specifically targeting Fluconazole-resistant strains. It demonstrates superior efficacy compared to Miconazole, exhibiting inhibitory activity against Candida albicans with minimum inhibitory concentration (MIC) values ranging from 0.03 to 0.25 μg/mL. This compound is valuable for research focused on overcoming antifungal resistance and developing novel treatments for fungal infections. -
Antifungal Agent
16,17-Dihydroheronamide C functions as an antifungal agent, targeting fungal growth through its unique mode of action. This compound aids in the analysis of the mechanistic pathways of heronamide C, making it an important tool for research in mycology and antifungal drug development. Its activity profile offers valuable insights into the development of new therapeutic strategies against fungal infections. -
Antifungal Agent
Antifungal Agent 76 is a potent antifungal compound that targets the fungal cell membrane leading to rapid fungicidal activity. It demonstrates a broad spectrum of antifungal activity with minimal inhibitory concentrations (MICs) ranging from 0.25 to 16 μg/mL. This compound is suitable for research applications related to antifungal drug development and studies of fungal cell membrane integrity. -
Antimycobacterial Agent
Antituberculosis agent-6 is a potent antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant activity with a minimum inhibitory concentration (MIC) of 3.49 μM. Additionally, Antituberculosis agent-6 exhibits notable antifungal efficacy against Aspergillus niger, with an MIC of 62.50 μM. The compound also shows high gastrointestinal absorption, making it a valuable candidate for further research in tuberculosis and fungal infections. -
Antifungal Agent
1-Methoxyberberine chloride is a natural plant alkaloid extracted from Corydalis longipes, primarily known for its antifungal properties. This compound has demonstrated significant efficacy against various fungal strains, making it valuable for research in antifungal therapies and the study of fungal infections. Its mechanism involves disrupting fungal cell membrane integrity, thus showcasing potential applications in drug development and infectious disease research. -
Antifungal Agent
Antifungal agent 92 is a potent antifungal compound that primarily targets mitochondrial function in Sclerotinia sclerotiorum, exhibiting an EC50 of 4.4 μM. This agent disrupts mitochondrial morphology, reduces mitochondrial membrane potential, and induces the accumulation of reactive oxygen species (ROS). Additionally, antifungal agent 92 serves as a moderate inhibitor of mitochondrial complexes II and III, making it a valuable tool for research into fungal pathogenesis and mitochondrial dysfunction. -
Isochromanone
Pseudoanguillosporin A is a naturally occurring isochromanone isolated from the fungus Cadophora sp. This compound exhibits potent antifungal activity against Cryptococcus neoformans, with a minimum inhibitory concentration (MIC50) of 40 μg/mL. Pseudoanguillosporin A is suitable for research applications focused on fungal infections and the elucidation of antifungal mechanisms. -
SDH Inhibitor
Y12196 is a potent succinate dehydrogenase inhibitor (SDHI) that demonstrates strong fungicidal activity against Fusarium graminearum. This compound targets the mitochondrial metabolic pathway, disrupting energy production in fungal cells. Y12196 is valuable for investigating the role of SDH in fungal metabolism and can be utilized in studies aimed at controlling plant pathogens. -
Antibacterial/Antifungal Agent
Antibacterial Agent 288 is a targeted antibacterial and antifungal compound derived from the mangrove fungus (No. B60) found in the South China Sea. This compound exhibits significant activity against a range of bacterial and fungal pathogens, making it a valuable tool for microbiological research. Its properties may support studies in infectious disease treatment and the development of new antimicrobial agents. -
Acylpeptide Antibiotic
Cepafungin III is an acylpeptide antibiotic derived from the culture broth of Pseudomonas species. This compound demonstrates significant inhibitory activity against yeast and fungi, as well as exhibiting antitumor properties against P388 leukemia in murine models, particularly when utilized in conjunction with Cepafungin I and II. Its multifaceted biological activity makes Cepafungin III a valuable reagent for research in antifungal and anticancer studies. -
Antimicrobial
Alterlactone is an antimicrobial compound that exhibits broad-spectrum activity against both bacterial and fungal pathogens. Its ability to effectively inhibit microbial growth makes it a valuable tool in research focused on infectious diseases and antimicrobial studies. Additionally, Alterlactone demonstrates strong radical scavenging properties, contributing to its potential utility in antioxidant research. -
Inositol Derivative
2-C-methylene-myo-inositol oxide (NSC 45109) is an inositol derivative that effectively induces pseudohyphae formation in Saccharomyces species. This compound serves as a valuable tool for studying yeast morphogenesis and cellular signaling pathways related to inositol metabolism. Its unique biological activity provides insight into the physiological processes and adaptations of fungal cells. -
Opioid Receptor Agonist
Hodgkinsine is an opioid receptor agonist that exhibits significant analgesic properties while also functioning as an NMDA receptor antagonist. This compound demonstrates anti-injurial effects, making it relevant for pain management research. Additionally, Hodgkinsine possesses antiviral, antibacterial, and antifungal activities, highlighting its potential utility in various pharmacological studies. -
Antifungal Agent
1-Phenylsemicarbazide acts as an antifungal agent through its ability to inhibit fungal growth. This compound has demonstrated potential in preventing mold proliferation on various industrial products, making it valuable for applications in material preservation and quality control in diverse industries. Its effectiveness in combating fungal contamination supports further exploration in research focused on antifungal development and industrial applications. -
Antimalarial Agent
(±)-Emodin bianthrone is a natural product with potent antimalarial properties. It has demonstrated significant activity against malaria-causing pathogens, contributing to its potential in therapeutic applications. Additionally, this compound exhibits antitubercular and antifungal activities, making it a valuable reagent for research in infectious disease studies and the development of novel treatments. -
Antifungal Agent
Tetramethylkaempferol is an antifungal agent that exhibits significant activity against Candida albicans, with an IC50 value of 17.63 µg/mL. This compound is valuable for research applications focused on fungal infections and the development of antifungal therapies. Its ability to inhibit the growth of pathogenic fungi makes it an important tool for studying antifungal mechanisms and treatments. -
1,3-β-glucan Synthase Inhibitor
Arborcandin F is a potent inhibitor of 1,3-β-glucan synthase, acting as an effective antifungal antibiotic. It displays IC50 values of 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, demonstrating significant antifungal activity. Arborcandin F also exhibits a minimum inhibitory concentration (MIC) of 2-4 μg/mL against the genus Candida, making it a valuable reagent for research into fungal infections and therapeutic applications. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 7 is a potent inhibitor of chitin synthase (CHS) with an IC50 value of 0.37 mM. This compound demonstrates broad-spectrum antifungal activity, particularly against drug-resistant fungi. It is valuable for research applications focused on fungal infections and understanding the role of chitin biosynthesis in fungal pathogens. -
Antifungal Antibiotic
Amphotericin A is a potent antifungal antibiotic that exerts its activity by binding to ergosterol in fungal cell membranes, leading to increased permeability and cell death. It demonstrates strong efficacy against a variety of fungal pathogens, making it a valuable tool in research focused on fungal infections and therapeutic interventions. Its use spans studies in drug resistance, mechanism of action, and the development of novel antifungal agents.
