Catalog No.
Product Name
Application
Product Information
Citations
-
Antifungal Agent
(±)-Coladonin is a coumarin derivative known for its antifungal activity. It demonstrates significant inhibitory effects against the plant pathogenic fungus Botrytis cinerea, a key causative agent of gray mold disease in crops. This compound is primarily utilized in research focused on the prevention and control of fungal infections in agricultural settings. -
Antifungal Agent
trans-β-Bergamotene is a sesquiterpene hydrocarbon that acts as an antifungal agent. Isolated from the essential oil of Bixa orellana L. leaves, it exhibits both antifungal and anti-inflammatory properties. This compound is particularly useful for research focused on Candida albicans infections, providing insights into potential therapeutic applications. -
Fungicide
Antifungal agent 121 is a benzimidazole-acrylonitrile derivative that acts as a potent fungicide. It exhibits significant efficacy against a broad spectrum of fungal pathogens, making it useful for various research applications in mycology and plant pathology. This compound is valuable for studying fungal resistance mechanisms and developing antifungal treatments. -
Fungal Inhibitor
Antifungal Agent 14, a potent fungal inhibitor, demonstrates broad-spectrum activity against various fungal strains with impressive minimum inhibitory concentration values. This compound is designed for use in research applications focusing on antifungal treatment and the investigation of fungal pathogenesis, making it a valuable tool for studying fungal infections and developing therapeutic strategies. -
Antifungal Peptide
Coccinin is an antifungal peptide that exerts its bioactivity by inhibiting HIV-1 reverse transcriptase. Isolated from the seeds of large scarlet runner beans, Coccinin demonstrates significant antifungal activity against a range of pathogens, including M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus, and R. solani, with IC50 values of 75, 81, 89, 109, 122, and 134 μM, respectively. This compound is valuable for research in antifungal therapeutics and HIV-related studies. -
Antifungal Agent
Albaconazole is a broad-spectrum triazole antifungal agent that primarily targets fungal sterol synthesis by inhibiting the enzyme lanosterol demethylase. Its mechanism effectively disrupts the membrane integrity of various fungal species. This compound is utilized in research applications focused on antifungal drug development and the study of fungal infections. -
Fungicide
Pyraoxystrobin is a quinone outside inhibitor (QoI) fungicide that targets mitochondrial respiration in fungi. It demonstrates potent antifungal activity with an EC50 value of 0.0094 μg/mL against Magnaporthe oryzae isolates. This compound is valuable for research applications focused on fungal disease management in rice cultivation. -
Antifungal Peptide
KK14(R) is an analog of the synthetic antifungal peptide KK14, demonstrating potent antifungal activity against Fusarium culmorum, Penicillium expansum, and Aspergillus niger, with minimum inhibitory concentrations (MICs) of 6.25 μg/mL, 12.5 μg/mL, and 12.5 μg/mL, respectively. This compound also exhibits stability under various heat and pH conditions. Additionally, KK14(R) shows cytotoxic effects on Caco-2 and RAW264.7 cell lines, making it a valuable tool for research in fungal infections and cytotoxicity studies. -
Antimicrobial Agent
Antibacterial Agent 73 (compound 7a) is a potent antimicrobial agent targeting infectious pathogens. It demonstrates significant antitubercular activity against Mycobacterium tuberculosis H37Rv, with a minimum inhibitory concentration (MIC) of 0.65 µg/mL. Additionally, this compound exhibits effective antifungal and antibacterial properties, along with notable cytotoxic effects in MCF-7 breast cancer cell lines, displaying an IC50 of 8.20 μM. Its multifunctional bioactivity positions it as a valuable tool for exploring antimicrobial resistance and evaluating therapeutic strategies in cancer research. -
Polysaccharide Copolymer
L-Diguluronic acid disodium is a linear polysaccharide copolymer primarily targeting the formation of alginate. This compound is composed of two L-guluronic acid units and serves as a versatile unbranched polyanionic polysaccharide. Its key biological activity includes potential applications in drug delivery systems, particularly for antifungal agents. L-Diguluronic acid disodium is valuable in research exploring innovative delivery mechanisms in therapeutic formulations. -
Antimicrobial Agent
Terbinafine lactate is a potent antimicrobial agent that primarily targets squalene epoxidase, inhibiting its activity with a Ki of 30 nM in Candida species. This compound exhibits strong antifungal properties and also demonstrates antibacterial effects against specific Gram-positive and Gram-negative bacteria. Additionally, Terbinafine lactate serves as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. -
Antifungal Agent
Antifungal Agent 55 is a selective antifungal compound targeting resistant strains of Candida albicans. It demonstrates significant inhibitory activity with minimum inhibitory concentrations (MIC) ranging from 0.25 to 1 μg/mL, surpassing the efficacy of traditional antifungal agents. This compound is invaluable for research on antifungal resistance and the development of new therapeutic strategies against fungal infections. -
Bacterial/Fungal Inhibitor
Pyruvic acid semicarbazone is a bacterial and fungal inhibitor. This compound demonstrates significant biological activity against various microbial strains, making it a valuable tool for investigating anti-infective agents. Additionally, pyruvic acid semicarbazone has potential applications in cancer research and plant growth regulation studies. -
Anti-infection Agent
Monocerin is an isocoumarin derivative with properties as an anti-infection agent. Derived from the endophytic fungus Microdochium bolleyi found in Fagonia cretica, Monocerin exhibits significant antifungal, antibacterial, and antialgal activities. It has demonstrated efficacy against pathogens such as Microbotryum violaceum, Escherichia coli, Bacillus megaterium, and Chlorella fusca, making it a valuable compound for research in infectious disease studies. -
Antimicrobial Agent
Hepcidin-20 (human) is a histidine-rich, cysteine-enriched peptide with a stable β-sheet structure, functioning as an antimicrobial agent. This peptide exhibits significant antifungal properties and has been shown to inhibit biofilm formation and disrupt bacterial cell metabolism in both polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains. Its unique mechanism makes it a valuable tool for research into antimicrobial resistance and the development of novel therapeutic strategies. -
Bactericide
Ditalimfos is an organophosphate bactericide that targets a range of pathogenic fungi. It is primarily employed in agricultural applications to effectively manage fungal diseases in various crops. Additionally, Ditalimfos serves as a valuable tool for research on fungal resistance mechanisms and for conducting environmental residue risk assessments. -
Antifungal Agent
1-O-Methylemodin is a natural product derived from Zopfiella longicaudata with demonstrated antifungal properties. It acts by inhibiting fungal growth, making it a valuable compound for research on fungal infections and potential therapeutic applications. Its unique structure contributes to its effectiveness in combating various fungal species, supporting studies in mycology and pharmacology. -
Antibiotic
Mildiomycin is an antibiotic derived from Streptoverticillium rimofaciens, primarily targeting powdery mildew in barley. It exhibits inhibitory activity against certain strains of Mycobacterium and Rhodotorula, making it useful for specific antimicrobial applications. However, it is ineffective against the majority of fungi and bacteria, limiting its broad-spectrum utility. -
CHS Inhibitor
Chitin Synthase Inhibitor 11 is a potent inhibitor of chitin synthase, demonstrating significant inhibitory activity with an IC50 value of 0.10 mM. This compound exhibits broad-spectrum antifungal properties in vitro, making it a valuable tool for investigating invasive fungal infections (IFIs). Its ability to disrupt chitin biosynthesis positions it as a promising candidate for enhancing understanding of antifungal mechanisms and therapies. -
Drug Derivative
Lindetannin is an A-type trimer of proanthocyanidin primarily derived from the bark of Cinnamomum trees. This polyphenolic compound exhibits significant antioxidant and anti-cancer properties, making it valuable in cancer research. Additionally, Lindetannin demonstrates anti-inflammatory, cardioprotective, antibacterial, and antifungal activities, providing potential therapeutic benefits for conditions such as chronic venous insufficiency, capillary fragility, sunburn, and retinopathy. -
Antifungal Agent
Antifungal Agent 34 (Compound 6i) targets fungal pathogens, demonstrating potent antifungal activity against Candida albicans, with a minimum inhibitory concentration (MIC) of 4 µg/mL. This compound significantly inhibits both hyphal growth and biofilm formation of Candida albicans, making it a valuable tool for investigating fungal pathogenesis and treatment methodologies. Importantly, Antifungal Agent 34 displays no cytotoxic effects on mammalian cells, indicating its potential for therapeutic applications. -
CHS Inhibitor
Chitin Synthase Inhibitor 12 targets chitin synthase, demonstrating potent inhibitory activity with an IC50 of 0.16 mM. This compound serves as a broad-spectrum antifungal agent, exhibiting significant efficacy against drug-resistant strains, including Candida albicans and Cryptococcus neoformans. Chitin Synthase Inhibitor 12 is suitable for research applications involving invasive fungal infections (IFIs). -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 14 is a selective inhibitor of chitin synthase (CHS), which plays a critical role in the synthesis of chitin, a key component of fungal cell walls. This compound exhibits significant antifungal activity and demonstrates effectiveness against drug-resistant fungal strains. It is valuable for research applications focused on fungal biology, drug resistance mechanisms, and the development of new antifungal therapies. -
Antifungal Agent
Antifungal Agent 52 is a tetrazole derivative that targets ergosterol synthesis. It exhibits significant antifungal activity against Candida albicans, effectively permeabilizing the cell membrane of sessile C. albicans. This compound is valuable for research applications focused on pathogenic fungi and the mechanisms of antifungal resistance. -
Antifungal Drug
Antifungal agent 100 (compound 3i) targets Succinate dehydrogenase (SDH) and demonstrates potent antifungal activity against S. sclerotiorum, with an EC50 value of 0.33 mg/L. Additionally, it displays an IC50 of 0.63 mg/mL against SDH, indicating its potential for disrupting key metabolic processes in fungal cells. This compound is particularly valuable for research applications aimed at understanding fungal pathogenesis and developing antifungal therapies. -
Fas1 Inhibitor
(Rac)-NPD6433 is a Fas1 inhibitor targeting the enoyl reductase domain of fatty acid synthase 1. As a triazenyl indole, it demonstrates broad-spectrum antifungal activity against various screening fungal strains. By covalently inhibiting flavin mononucleotide-dependent NADPH-oxidation activity, (Rac)-NPD6433 effectively disrupts essential fatty acid biosynthesis, making it a valuable tool for research in fungal metabolism and potential therapeutic applications. -
β-Glucanase
Beta-Glucanase is an enzyme from the glycosyl hydrolase family that catalyzes the hydrolysis of β-glucan polysaccharides. This reaction results in the formation of 3-O-cellotriosyl-d-glucose and 3-O-cellobiosyl-d-glucose. Beta-Glucanase plays a crucial role in plant defense mechanisms by providing resistance against various fungal pathogens, making it valuable for research in plant biology and disease resistance studies. -
Fungicide
Fosetyl-aluminum is a foliar-applied fungicide that primarily targets downy mildew and other diseases caused by Phytophthora spp. It exhibits significant biological activity in preventing and controlling various plant pathogens, making it essential for protecting agricultural and horticultural crops. Its application is crucial for maintaining crop health and yield in environments prone to fungal infections. -
Fungal Inhibitor
Antifungal agent 15 is a potent fungal inhibitor that exhibits significant biological activity, demonstrated by EC50 values of 0.52 μg/mL against Sclerotinia sclerotiorum and 0.50 μg/mL against Botrytis cinerea. This compound is suitable for research applications aimed at understanding fungal pathogenesis and developing antifungal therapies. Its high efficacy makes it a valuable tool for investigating fungal resistance mechanisms and optimizing treatment strategies in agricultural and clinical settings. -
CaMdr1p Inhibitor
CaMdr1p-IN-1 is a specific inhibitor of the major facilitator superfamily transporter CaMdr1p. This compound demonstrates significant chemosensitizing effects, particularly in enhancing the efficacy of Fluconazole against CaMdr1p-overexpressing Candida albicans, achieving a minimum inhibitory concentration (MIC) of 10 μM. CaMdr1p-IN-1 is valuable for research focused on antifungal drug resistance mechanisms and the development of combination therapies against fungal pathogens. -
Fungal Inhibitor
Neocnidilide is an alkylphthalide that acts as a fungal inhibitor, specifically targeting mycotoxin-producing fungi to suppress their growth. Additionally, it exhibits larvicidal properties against Drosophila melanogaster, with a lethal concentration (LC50) of 9.9 μmol/mL. This compound is relevant for research applications focused on mycology and pest control in agricultural settings. -
Fungicide
Flutianil is a targeted fungicide that primarily inhibits the growth of powdery mildew species. Its mode of action involves interfering with haustorium formation, leading to reduced mycelial development. Flutianil is of particular interest in agricultural research for its efficacy in managing fungal diseases in crops, contributing to improved plant health and yield. -
Hydroxyflavan
4-Hydroxyflavan is a hydroxyflavan compound that demonstrates antifungal activity, specifically exhibiting efficacy against sporelings of Botrytis cinerea with an effective dose (ED50) of 216 μM. This compound is utilized in antifungal research and may serve as a valuable tool for studying the mechanisms of fungal inhibition and pathogenicity. -
Antifungal Agent
Pygenic acid B is a triterpenoid compound isolated from the leaves of Glochidion obliquum, exhibiting significant antifungal activity against Candida musae. Additionally, it demonstrates ONOO- scavenging properties, making it a valuable tool for research in antifungal mechanisms and oxidative stress studies. This compound can aid in the development of novel antifungal agents and enhance understanding of reactive nitrogen species in biological systems. -
Antifungal Agent
Antifungal agent 158 is an α-pyrone derivative that targets plant-pathogenic fungi, exhibiting notable antifungal activity against species such as Chaetomium spp., Curvularia lunata, and Aspergillus flavus. This compound is characterized by its non-toxic profile towards greenhouse-grown crops, including bean, corn, and tobacco plants. Antifungal agent 158 is an effective tool for research focused on the treatment and study of Aspergillus flavus infections. -
Antibacterial Agent
NK 1971 is an antibacterial agent that exhibits promising antifungal activity. This compound has been studied for its effects on microbial infections and may impact neurological functions, potentially leading to decreased motor skills and seizures in animal models. Its diverse biological activity makes it a valuable tool for research in microbial pathogenesis and therapeutic interventions. -
Antifungal Agent
5-Heptadec-cis-8-enylresorcinol is a 5-alkylresorcinol with antifungal properties, primarily targeting the rice blast fungus. Isolated from etiolated rice seedlings, this compound exhibits mechanisms that mediate DNA relaxation, contributing to its antifungal activity. It is valuable for research applications focused on plant pathology and antifungal agent development. -
NSAIA
Tropesin, a nonsteroidal anti-inflammatory agent (NSAIA), exhibits significant inhibitory activity against the growth of Trichoderma viride. Its mechanism of action involves the modulation of inflammatory pathways, making it a valuable tool for studying fungal growth and related biological processes. This compound is suitable for research applications focused on inflammation and antifungal activity in diverse biological systems. -
Antibacterial Agent
RMG8-8 is an antibacterial agent with demonstrated efficacy against Cryptococcus neoformans, exhibiting an IC50 of 1.56 μg/mL. This compound is valuable for research focused on fungal infections and therapeutic development. Its potent activity provides a useful tool for screening and evaluating new antifungal strategies. -
Fungal
Zaragozic acid A trisodium is a fungal metabolite that functions as a reversible competitive inhibitor of squalene synthase. This compound exhibits potent antifungal activity by disrupting sterol biosynthesis, making it valuable in the study of fungal pathogens. Its applications include research in antifungal drug development and investigations into the mechanistic pathways of sterol biosynthesis in various fungi. -
Antifungal Agent
Bis(methylthio)gliotoxin is an antifungal agent with enhanced stability compared to gliotoxin, making it a more reliable biomarker for invasive aspergillosis. Its application in clinical diagnostics provides improved accuracy in the identification of Aspergillus infections, facilitating timely intervention and management. This compound is essential for research into fungal pathogenesis and the development of antifungal therapies. -
Antifungal Agent
Amphotericin X1 is a 13-O-methyl derivative of Amphotericin B, acting as a potent antifungal agent. It demonstrates significant inhibitory activity against various fungal pathogens, including Candida albicans, C. parapsilosis, Cryptococcus neoformans, Aspergillus niger, and A. fumigatus, with minimum inhibitory concentration (MIC) values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL, and 2 μg/mL, respectively. This compound is particularly valuable for research applications focused on fungal infections and the development of antifungal therapies. -
Antibacterial And Antifungal Agent
5CF2PB is an antibacterial and antifungal agent that targets the 5O4L protein. This compound demonstrates potent activity against a range of bacterial and fungal pathogens, particularly exhibiting significant efficacy against Pseudomonas aeruginosa and Aspergillus niger. 5CF2PB is valuable for research applications focused on infections and resistance mechanisms in microbial agents. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 3 is a selective inhibitor of chitin synthase, exhibiting an IC50 value of 0.16 mM. This compound demonstrates significant antifungal activity, with a minimum inhibitory concentration (MIC) of 1 µg/mL against Candida albicans. It is primarily utilized in research applications focusing on antifungal drug development and the study of chitin biosynthesis pathways in pathogenic fungi. -
Antifungal Agent
Antifungal agent 73 (compound A32) is an effective antifungal agent targeting azole-resistant candidiasis. It disrupts the integrity of the fungal cell wall and cell membrane, demonstrating significant in vivo antifungal activity against pathogenic fungi, including fluconazole-resistant strains. This compound is valuable for research applications focusing on antifungal resistance mechanisms and therapeutic strategies. -
Anticancer/antibacterial Agent
Antioxidant/anticancer agent 1 is a pyrimidine-derivatized Schiff base derived from pyrimidine hydroxy-1-naphthaldehyde, targeting multiple biological pathways. This compound exhibits significant antibacterial, antioxidant, antifungal, and anticancer activities, making it a valuable reagent for diverse research applications. Its multifaceted biological properties position it as a candidate for further investigation in cancer and infectious disease studies. -
Antifungal Agent
Galanolactone is a natural compound derived from the seeds of Alpinia galanga, primarily recognized for its antifungal properties. This agent exhibits significant cytotoxic effects against KB cells, with an EC50 value of 38.5 µg/ml. Galanolactone serves as a valuable tool in research focused on fungal inhibition and cytotoxicity studies. -
Antifungal Agent
Antifungal Agent 37 is a heterocyclic disulfide compound that exhibits significant antifungal activity. It is primarily utilized in research focused on fungal pathogens, providing insights into mechanisms of action and potential therapeutic applications. This compound serves as an essential tool in the development of novel antifungal agents for combating resistant strains. -
Antibiotic
Malolactomycin C is a macrolide antifungal antibiotic targeting fungal pathogens. Isolated from Streptomyces strain KP-3144, it demonstrates potent inhibitory activity against Botrytis cinerea, a key agent of gray mold in plants. This compound is valuable for research in plant disease management and the development of antifungal agents. -
Antifungal Agent
Antifungal agent 51 (Compound 5c) is a potent antifungal agent primarily targeting various Candida species, including Candida albicans, Candida parapsilosis, and Candida tropicalis. It exhibits exceptional antifungal activity with a minimum inhibitory concentration (MIC) of less than 0.063 μg/mL. Notably, it demonstrates low cellular toxicity and possesses no carcinogenic properties, making it a valuable tool for antifungal research and development.
