Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Anguinomycin A is an antibiotic with potent inhibitory activity against Ganoderma boninense, exhibiting a minimum inhibitory concentration (MIC) of 5 µg/disk. In addition to its antibacterial properties, Anguinomycin A demonstrates significant antitumor activity. This compound is valuable for research in microbial resistance and cancer therapeutics. -
Antifungal Agent
Antifungal Agent 74 is a potent antifungal compound that exhibits significant fungicidal activity against pathogens such as Colletotrichum arachidicola and Rhizoctonia solani. Its mechanism of action involves the disruption of steroid biosynthesis and ribosome biogenesis in eukaryotic organisms, making it a valuable tool in antifungal research and the study of fungal pathogenesis. Suitable for applications in both laboratory and agricultural settings, Antifungal Agent 74 offers potential for the development of new antifungal strategies. -
antifungal
Lactose octaacetate primarily exhibits antifungal activity, demonstrating mild to moderate effects against certain fungi while showing minimal or no activity against bacteria and yeast. This compound displays low cytotoxicity toward MDBK, Hep-2, and MDCK cells, making it a candidate for further safety assessments in biological research. Additionally, lactose octaacetate has been identified to possess antiviral properties against PV-1, suggesting potential applications in virology studies. -
Anti-Plant Pathogenic Fungal
Verlamelin B is a novel compound targeting plant pathogenic fungi. It demonstrates significant protective activity in vivo, particularly against rice blast and barley powdery mildew, providing insights into antifungal mechanisms. Furthermore, Verlamelin B induces morphological alterations in fungal cells, including swelling and expansion. Despite its weaker in vitro activity against certain plant pathogens like Dipolaris zeae and Botrytis cinerea, this compound is a valuable tool for research into antifungal strategies against agricultural pathogens. -
SDH Inhibitor
SDH-IN-4 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 0.28 μg/mL. This compound demonstrates potent antifungal activity, specifically against Rhizoctonia solani, with an EC50 value of 0.23 μg/mL. SDH-IN-4 is primarily utilized in research applications involving fungal pathogen studies and metabolic pathway analysis. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 6 is a potent inhibitor of chitin synthase (CHS) with an IC50 value of 0.21 mM. This compound exhibits broad-spectrum antifungal activity against drug-resistant fungi, making it a valuable tool in the study of fungal infections. It is applicable in research focused on understanding fungal pathogenesis and developing antifungal therapies. -
Phytotoxin
Neovasinin is a phytotoxin derived from the fungus Neocosmospora vasinfecta. It demonstrates significant toxicity towards soybean plants, serving as a valuable model for studying plant-fungal interactions and the mechanisms of plant defense. This compound can be utilized in research focused on plant pathology and agricultural biotechnology. -
Fungal Inhibitor
Antifungal Agent 68 is a potent inhibitor targeting fungal ergosterol biosynthesis, with demonstrated efficacy against Candida species and Cryptococcus gattii. This compound likely exerts its antifungal effects by inhibiting lanosterol 14α-demethylase (CYP51), wherein its imidazole ring interacts with the heme group of the enzyme. It serves as a valuable tool for research into fungal infections and the development of novel antifungal therapies. -
Antifungal Agent
Amcipatricin L-aspartate is a semi-synthetic polyene antibiotic that targets fungal cell membranes, exhibiting potent broad-spectrum antifungal activity. This reagent is suitable for research applications focused on fungal infections and the development of antifungal therapies. Its ability to disrupt cellular integrity makes it a valuable tool in studying antifungal mechanisms and treatment strategies. -
Antifungal Antibiotic
Aranorosin is a potent antifungal antibiotic that targets fungal cell membrane integrity. Isolated from the culture filtrate and mycelium of the fungus Pseudoarachniotus roseus Kuehn, it exhibits significant antifungal activity against various pathogenic fungi. This compound is valuable for research applications focused on fungal pathogenesis and therapy development. -
β-1,3-Glucan Inhibitor
Ibrexafungerp phosphate is a selective inhibitor of β-1,3-glucan synthesis, exhibiting notable antifungal activity. This compound is primarily utilized in research related to fungal pathogens, particularly for investigating infections caused by Candida and Aspergillus species. Its mechanism of action disrupts the integrity of the fungal cell wall, making it a valuable tool for exploring antifungal therapies. -
Ole1p Inhibitor
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is an inhibitor of Ole1p desaturase, an important enzyme in the biosynthesis of unsaturated fatty acids. This compound exhibits antifungal activity, making it a valuable tool for research in antifungal drug development and lipid metabolism studies. It is suitable for investigating the mechanisms of fungal resistance and characterizing lipid profiles in various biological systems. -
Fungicidal Agent
Antibacterial agent 157 (compound B12) is a potent fungicidal agent that inhibits protein synthesis in the fungal pathogen Botrytis cinerea. This compound is valuable for research applications focused on gray mold resistance control, providing insights into effective strategies for managing plant diseases associated with this pathogen. -
Antibacterial Peptide
Metchnikowin is an antibacterial peptide derived from fruit flies, exhibiting potent antimicrobial properties against both bacteria and fungi. Its activity is regulated through the TOLL and IMD signaling pathways, making it a valuable tool for studying immune responses in various infectious conditions. This peptide is widely utilized in research focused on host defense mechanisms and the development of novel antimicrobial agents. -
Antifungal Agent
Asperfuran is an antifungal dihydrobenzofuran derivative derived from Aspergillus oryzae. It exhibits a weak inhibitory effect on chitin synthase from Coprinus cinereus, contributing to its antifungal activity. Additionally, Asperfuran demonstrates weak cytotoxicity in HeLa S3 and L1210 cell lines, with an IC50 of 25 μg/ml, making it a potential candidate for research involving fungal infections and cytotoxicity studies. -
Anti-Saprolegnia compound
Quellenin is an anti-saprolegnia compound derived from the deep-sea fungus Aspergillus sp. YK-76. It exhibits potent inhibitory activity against Saprolegnia species, making it a valuable tool in research applications focused on fungal infections in aquatic environments. This compound is particularly relevant for studies investigating antifungal agents and their potential use in aquaculture. -
Dimeric Antioxidant
Scirpusin B is a dimeric antioxidant derived from Scirpus maritimus L. It demonstrates notable biological activities, including antitumor, antifungal, insecticidal, and plant growth inhibitory effects. This compound is useful in research related to oxidative stress, cancer biology, and agricultural applications. -
Fungal Inhibitor
Antifungal agent 13 is a potent fungal inhibitor specifically targeting Sclerotinia sclerotiorum, exhibiting an effective concentration (EC50) of 1.25 mg/L. This compound demonstrates significant antifungal activity, making it a valuable tool for research into fungal pathogenesis and susceptibility. Its application includes studies aimed at understanding fungal resistance mechanisms and the development of novel antifungal therapies. -
Polyketide
(-)-Mitorubrinic acid is a polyketide that serves as a virulence factor for Penicillium marneffei. It is synthesized through the activity of two non-reducing polyketide synthase (PKS) genes, pks12 and pks11, operating in a sequential manner. This compound enhances the intracellular survival of P. marneffei within macrophages, making it significant for research on fungal pathogenesis and virulence mechanisms. -
Phytoalexin
Noraucuparin is a biphenyl-type phytoalexin that exhibits significant antifungal activity. This compound is of interest in botanical research due to its natural defense role in plants, particularly in response to pathogenic attacks. Isolated from the leaves of Sorbus pohuashanensis, noraucuparin serves as a valuable tool for studying plant-pathogen interactions and the mechanisms of phytochemical defenses. -
Anti-bacterial Peptide
Pseudin-2 is an antimicrobial peptide derived from the skin of the South American paradoxical frog, Pseudis paradoxa. It exhibits potent growth inhibition against Gram-negative bacteria, making it a valuable tool for antibacterial research. Pseudin-2 may be utilized in studies aimed at understanding antimicrobial mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antifungal Reagent
L685818 is a specific immunophilin ligand that exhibits antifungal activity against Cryptococcus neoformans. In addition to its antifungal properties, L685818 demonstrates neuroregenerative effects by safeguarding dopaminergic neurons from toxicity associated with MPP+ and 6-OHDA. The compound effectively reduces the loss of tyrosine hydroxylase (TH) and promotes neuronal process regeneration, making it a valuable tool for research in neurodegenerative disease models and fungal infections. -
Fungal Inhibitor
Diethofencarb is a fungicide that exhibits potent activity against Botrytis cinerea and Benzimidazole-resistant strains of Botrytis species. It functions primarily as an antifungal agent in agricultural applications, demonstrating efficacy in managing fungal pathogens in crops. Researchers may utilize Diethofencarb for studies related to fungal resistance mechanisms and the development of sustainable pest management strategies. -
Antifungal Agent
Neophellamuretin is a flavonoid that acts as an antifungal agent. It demonstrates potent inhibitory activity against Trichophyton species, with a minimum inhibitory concentration (MIC) value of 62.5 µg/mL. This compound is suitable for research applications focused on fungal infections and the development of antifungal therapies. -
Antifungal Agent
Antifungal Agent 95 (Compound CN21b) is an effective antifungal compound targeting Sclerotinia sclerotiorum and Botrytis cinerea, demonstrating EC50 values of 2.11 μM and 0.97 μM, respectively. This agent shows significant antifungal activity against resistant B. cinerea strains, with EC50s below 10 μM. It is suitable for research applications aimed at understanding fungal resistance mechanisms and the development of antifungal strategies. -
Antifungal Agent
Embeconazole is an antifungal agent primarily targeting key pathogens such as Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus, and Aspergillus flavus, with minimum inhibitory concentrations (MICs) of 8, 16, 63, and 250 μM, respectively. This compound demonstrates significant antifungal activity, making it suitable for research applications focused on fungal infections and the development of antifungal therapies. Its efficacy against various fungal species highlights its potential use in both clinical and laboratory settings for studying fungal pathogenesis and treatment options. -
Fungal Inhibitor
Antifungal agent 11 targets fungal organisms by inhibiting key metabolic processes, demonstrating significant antifungal activity. This compound is valuable in research applications aimed at understanding fungal behavior and developing new antifungal treatments. Its efficacy against various fungal strains makes it an essential tool for studying fungal infections and resistance mechanisms. -
Fungal
Bivittoside B is a non-sulfated hexoside analog that targets fungal cells, exhibiting significant antifungal properties. This compound has demonstrated potential antitumor activities, making it a valuable tool for research in mycology and cancer biology. Its unique structure and biological activity may provide insights into novel therapeutic strategies against fungal infections and tumors. -
Antifungal Agent
Fluazinam impurity 1 is an impurity associated with the antifungal agent Fluazinam. It exhibits significant antifungal activity against various pathogens, including Sphaerotheca fuliginea, Pyricularia oryzae, and Rhizoctonia solani. This compound serves as a valuable tool for research focused on antifungal mechanisms and can aid in the development of strategies to combat fungal infections in agricultural settings. -
Antifungal Agent
Antifungal Agent 69 is a eugenol-imidazole compound exhibiting potent activity against Candida albicans, with a minimum inhibitory concentration (MIC) of 4.6 μM. It effectively disrupts ergosterol biosynthesis in fungi, contributing to its antifungal properties. This compound demonstrates minimal cytotoxicity, making it suitable for further research in antifungal treatments and mechanisms of action. -
Anti-MTB/Antifungal Agent
Bromoflavone, a flavone derived from Aspergillus candidus, primarily targets Mycobacterium tuberculosis (MTB) with an MIC90 value of 1.2 μM, demonstrating significant anti-MTB activity. Additionally, it exhibits antifungal properties, inhibiting the growth of pathogenic fungi such as Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus, with IC50 values of 0.11, 20, and 0.54 μg/mL, respectively. This compound is valuable for research in tuberculosis and fungal infections, offering insights into potential therapeutic applications. -
Antifungal Agent
Alexidine is a bis-biguanide compound with potent antifungal properties, effectively inhibiting a variety of fungal pathogens and demonstrating significant antibiofilm activity. Additionally, Alexidine serves as an anticancer agent by targeting the mitochondrial tyrosine phosphatase PTPMT1 in mammalian cells, inducing mitochondrial apoptosis. This makes Alexidine a valuable reagent for research applications in antifungal therapy and cancer studies. -
CHS Inhibitor
Chitin Synthase Inhibitor 10 is a potent chitin synthase inhibitor, demonstrating an IC50 value of 0.11 mM. This compound exhibits significant antifungal activity, particularly against drug-resistant fungal strains such as Candida albicans and Cryptococcus neoformans. Chitin Synthase Inhibitor 10 is useful in the study of invasive fungal infections (IFIs), providing valuable insights into potential therapeutic strategies. -
Gamma-Glutamyl Transferase Inhibitor
Gamma-Glutamyl Transferase-IN-2 is a potent inhibitor of gamma-glutamyl transferase, a key enzyme involved in amino acid metabolism. This β-carboline 1-hydrazide compound demonstrates significant antifungal and antibacterial activities through its mechanism, which leads to the accumulation of reactive oxygen species, disruption of cell membranes, and alteration of histone acetylation patterns. Gamma-Glutamyl Transferase-IN-2 is valuable for research focused on understanding oxidative stress, cellular integrity, and epigenetic regulation in various biological systems. -
Antifungal Agent
Eriobofuran is an antifungal agent derived from Sorbus aucuparia. It exhibits significant antifungal activity, making it a valuable reagent for studies focused on fungal pathogens. Eriobofuran is applicable in research aimed at understanding fungal resistance mechanisms and developing novel antifungal therapies. -
Antifungal Agent
AB-22 is a vinyl sulfate compound that functions as an orally active antifungal agent. It effectively inhibits hyphal growth and biofilm formation in Candida albicans SC5314 by suppressing the expression of key genes such as ALS3, HWP1, and ECE1. AB-22 is a valuable tool for research into fungal infections, including systemic candidiasis. -
SDH Inhibitor
SDH-IN-6 is a potent inhibitor of succinate dehydrogenase (SDH). This compound demonstrates significant antifungal activity against Valsa mali, exhibiting an EC50 value of 1.77 mg/L. It is a valuable research tool for investigating the role of SDH in fungal metabolism and potential therapeutic approaches for treating fungal infections. -
Antifungal Agent
Antifungal agent 75 (compound 6r) is a potent antifungal compound targeting Candida albicans. It effectively inhibits C. albicans biofilm formation and enhances cell membrane permeability. Additionally, it reduces ergosterol levels, disrupts membrane structure, and compromises cellular integrity, showcasing remarkable antifungal activity. This reagent is suitable for research applications focused on antifungal drug development and cellular membrane studies. -
Cholesterol Biosynthesis Inhibitor
Agistatin B is a mycotoxin derived from fungal sources that serves as a cholesterol biosynthesis inhibitor. This compound effectively disrupts the biosynthetic pathway of cholesterol, making it a valuable tool for studying lipid metabolism and related disorders. Its inhibition of cholesterol synthesis positions Agistatin B as an important reagent for research in areas such as cardiovascular disease and metabolic regulation. -
Polyketide Metabolite
Monaschromone, a polyketide metabolite, exhibits potent antifungal activity by significantly inhibiting the growth of various pathogens including Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Ganoderma saubinettii. The minimum inhibitory concentration (MIC) values for these organisms range from 6.25 to 12.5 μM. This compound is valuable for research applications focused on antifungal drug discovery and the study of plant-pathogen interactions. -
Antibiotic
Viridicatumtoxin is a potent antibiotic derived from the fungus Penicillium viridicatum, demonstrating significant antimicrobial activity. With an LD50 of 122.4 mg/kg in rat models, this mycotoxin may have potential applications in the study of bacterial resistance and the development of new antimicrobial therapies. It serves as a valuable tool for researchers investigating the pharmacological properties of novel antibiotics. -
Synthesis Dextran Inhibitor
MK-5204 is an orally active inhibitor of β-1,3-glucan synthesis, targeting the pathways involved in fungal cell wall formation. Its primary mechanism disrupts the synthesis of glucans, which are essential for fungal structural integrity. This compound serves as a valuable tool in antifungal research and development, enabling the study of fungal pathogenesis and the evaluation of novel therapeutic strategies. MK-5204 is particularly useful in elucidating the role of glucans in fungal virulence and resistance mechanisms. -
Fungal Inhibitor
Fusapyrone is a broad-spectrum antifungal metabolite that targets fungal growth by inhibiting specific pathways in various fungal species. Initially isolated from Fusarium species, it demonstrates significant efficacy against ochratoxin-producing strains of Aspergillus section Nigri, making it valuable in the control of postharvest crop diseases. Its application in agricultural research allows for the exploration of novel antifungal strategies to enhance crop quality and safety. -
Antifungal/antimitotic/anti-HIV-1 Agent
Wikstrol A is a potent antifungal, antimitotic, and anti-HIV-1 agent that primarily targets fungal and viral proliferation. This compound induces significant morphological deformation of the mycelia of P. oryzae, with a minimum effective concentration (MMDC) of 70.1 µM, and demonstrates inhibition of microtubule polymerization with an IC50 value of 131 µM. Furthermore, Wikstrol A exhibits anti-HIV-1 activity, showcasing an IC50 value of 67.8 µM, making it relevant in therapeutic research against both fungal infections and HIV-1. -
Fungal Inhibitor
Oxaziclomefone is a broad-spectrum fungicide that inhibits the growth of several plant pathogenic fungi. It exhibits significant antifungal activity, making it an effective agent in the control of various crop diseases. Oxaziclomefone is utilized in agricultural applications to safeguard crops, enhancing both yield and quality. -
Antifungal Agent
Antifungal Agent 50 is a potent antifungal compound targeting fungal cell membranes. It demonstrates minimal inhibitory concentrations (MICs) ranging from <0.063 to 1 μg/mL, indicating strong antifungal activity. This reagent is suitable for research applications involving the study of fungal infections and the development of antifungal therapies. -
Antitumor Antibiotic
Mazethramycin B is an antitumor antibiotic derived from Streptomyces thioluteus ME561-L4. It exhibits broad-spectrum antimicrobial activity, with minimum inhibitory concentrations of 1.56 μg/mL against Bacillus subtilis and 6.25 μg/mL against Candida pseudotropicalis. Mazethramycin B has shown significant efficacy in enhancing survival rates in L1210 leukemia mouse models, highlighting its potential for further research in cancer treatment and antimicrobial applications. -
Antifungal Metabolite
Eucalyptacid A is an antifungal metabolite that demonstrates significant antifungal activity against Alternaria solani, with minimum inhibitory concentration (MIC) values ranging from 6.25 to 50 μM. This compound is suitable for research applications focused on antifungal mechanisms and studying phytopathogen interactions. Its effectiveness positions it as a valuable tool for investigating potential antifungal treatments in agricultural and biomedical research. -
Antifungal Agent
Variotin is an antifungal agent that demonstrates potent antibiotic activity against dermatophytes, including Trichophyton, Microsporum, and Epidermophyton. Additionally, it is effective against pathogenic fungi associated with internal mycoses, such as Blastomyces and Cryptococcus. This compound is suitable for research applications focused on fungal infections and the mechanisms of antifungal resistance. -
Succinate Dehydrogenase Inhibitor
SDH-IN-8 is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 27 nM in porcine SDH assays. This compound exhibits significant fungicidal activity, making it a valuable tool for investigating the role of SDH in fungal metabolism and potential therapeutic applications in fungal infections. Researchers may utilize SDH-IN-8 to explore mechanisms of SDH inhibition and its effects on cellular respiration and metabolic pathways.
