Catalog No.
Product Name
Application
Product Information
Citations
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Antitumor Agent
Kievitone is an isoflavanone that demonstrates significant antitumor activity. Isolated from the hypocotyls of Phaseolus vulgaris L. infected by Rhizoctonia solani Kühn, Kievitone also exhibits antifungal properties. This compound serves as an important tool for researchers investigating cancer biology and the mechanisms of antifungal defense. -
Macrolide Antibiotic
Oligomycin C is a macrolide antibiotic that specifically inhibits ATP synthase, thereby disrupting mitochondrial function. This compound demonstrates potent antifungal activity against a range of pathogens, including Aspergillus niger, Alternaria alternata, Botrytis cinerea, and Phytophthora capsici, making it a valuable tool for studying fungal infections and mitochondrial bioenergetics. Its selective action on fungi, with no antibacterial activity, further emphasizes its utility in antifungal research applications. -
Secondary Metabolite
Neosartoricin B is a secondary metabolite produced by Aspergillus nidulans. It has been shown to exert immunomodulatory effects, potentially influencing host interactions during fungal infections and colonization. This compound serves as a valuable tool in research focused on fungal pathogenesis and host defense mechanisms. -
Antifungal Agent
Antifungal Agent 98 primarily targets fungal pathogens and exhibits significant antifungal activity. At a concentration of 100 μg/mL, it demonstrates efficacy against various harmful fungi, including Bipolaris sorokinianum, Fusarium oxysporium f. sp. vasinfectum, Pyricularia oryzae, Alternaria brassicae, and Alternaria alternata, achieving death rates of 41.5%, 40.0%, 23.4%, 36.8%, and 35.0%, respectively. This compound is valuable for research focused on fungal control and plant health management. -
Antifungal Agent
Antifungal Agent 48 is a potent antifungal compound targeting Cryptococcus neoformans. Demonstrating a minimum inhibitory concentration (MIC) of 11 μM, it exhibits significant antifungal activity. This reagent is suitable for research applications focused on fungal infections and the development of antifungal therapies. -
Antifungal Agent
Caulilexin C is a phytoalexin derived from cruciferous plants that exhibits potent antifungal properties. It plays a significant role in plant defense by inhibiting the growth of various fungal pathogens. This compound is of particular interest in agricultural research for developing antifungal strategies and understanding plant-fungal interactions. -
Fungicide
Phenamacril is a potent fungicide that non-competitively inhibits myosin I activity, achieving an IC50 of 360 nM by suppressing ATPase activity. This compound demonstrates significant antifungal efficacy against Fusarium species, making it a valuable tool for research in fungal pathogenesis and the development of antifungal agents. -
Serine Palmitoyltransferase Inhibitor
Lipoxamycin is a potent serine palmitoyltransferase inhibitor, exhibiting an IC50 of 21 nM. This compound demonstrates significant antifungal activity, making it a valuable tool for studying lipid metabolism and sphingolipid biosynthesis. Lipoxamycin is applicable in research focused on fungal infections and potential avenues for therapeutic interventions targeting lipid-related pathways. -
Antifungal Agent
Voriconazole N-oxide is a potent antifungal agent primarily targeting fungal cell membrane biosynthesis. This compound exhibits both phototoxic and photocarcinogenic properties, which are important considerations in its biological evaluation. Additionally, Voriconazole N-oxide does not sensitize keratinocytes to ultraviolet B (UVB), making it relevant for studies in dermatological applications and the investigation of keratinocyte response to UV exposure. -
Antibacterial Compound
Di-O-methylhonokiol is a natural phenolic compound with notable antibacterial properties. It exhibits significant activity against Gram-positive bacteria, acid-fast bacilli, and various yeast and filamentous fungi. This compound is valuable for research applications focused on fungal infections and the development of antibacterial agents. -
Antibacterial Agent
(±)9-HpODE is a long-chain lipid hydroperoxide derived from the peroxidation of linoleic acid. This compound can induce the oxidation of intracellular glutathione (GSH), leading to alterations in cellular redox state. Additionally, (±)9-HpODE demonstrates antibacterial and antifungal activity, making it a valuable reagent for research into microbial pathogenesis and oxidative stress responses. -
Metal Complex
Chlorotris(triphenylphosphine)copper (CuCl(TPP)₃) is a DNA-targeted metal complex that interacts with DNA through non-covalent binding mechanisms, primarily utilizing the copper(I) center. This compound exhibits significant biological activities, including antibacterial, antifungal, and antitumor effects. It is valuable for research applications focused on the development of novel antimicrobial and anticancer agents, as well as studies investigating antioxidant properties. -
Antifungal Agent
Harzianum A is a trichothecene compound with potent antifungal activity. While it exhibits no antibacterial effects against Gram-negative and Gram-positive bacteria, it demonstrates cytotoxicity towards tumor cells. This compound is valuable for research applications focused on fungal infections and cancer therapeutics. -
Fungicide
Sedaxane is a novel broad-spectrum fungicide that targets the succinate dehydrogenase complex in fungal mitochondria, effectively inhibiting fungal respiration. This compound demonstrates extensive activity against various seed-borne and soil-borne fungal pathogens. Sedaxane is particularly useful in studying barley loose smut and barley stripe disease, providing valuable insights into fungal resistance and pathogen interaction in agricultural research. -
Fungal
Metiram is a polymeric dithiocarbamate fungicide that acts by inhibiting fungal growth and reproduction. It is commonly utilized in agricultural settings to protect a variety of crops, including tomatoes, potatoes, apples, and grapevines, from fungal diseases. Metiram plays a critical role in integrated pest management strategies, particularly for controlling significant plant health threats that may not be effectively managed through non-chemical methods. -
SDH Iinhibitor
SDH-IN-5 is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 3.293 μM. It exhibits significant antifungal activity, achieving an EC50 of 0.046 μg/mL against Rhizoctonia solani. In agricultural applications, SDH-IN-5 effectively inhibits the growth of R. solani in rice leaves, showcasing substantial protective and curative efficacies against this pathogen. -
Tau Aggregation Inhibitor
Nimbin is a potent tau aggregation inhibitor derived from the limonoid class of compounds found in Azadirachta. It is shown to enhance cell viability while effectively inhibiting the envelope protein of the dengue virus. Additionally, Nimbin exhibits a range of biological activities, including anti-inflammatory, antifungal, antihistamine, antiseptic, antioxidant, anticancer, and antiviral properties. This diverse activity profile makes Nimbin a valuable reagent for research in neurodegenerative diseases and viral infections. -
Antifungal agent
Tolprocarb is an antifungal agent that targets the polyketide synthase enzyme involved in melanin synthesis. It exhibits potent inhibitory activity against the rice blast fungus, Magnaporthe grisea. This compound is widely utilized in research applications focusing on fungal pathogen control and plant disease management. -
Antibacterial And Antifungal Agent
2,4-Dinitrobenzenesulfonamide is an antibacterial and antifungal agent that targets dihydrofolate synthetase. It exhibits significant inhibitory activity against various microorganisms, including Aspergillus niger, Candida albicans, Bacillus subtilis, and Staphylococcus aureus. This compound is valuable for research applications focused on antimicrobial activity and the study of folate metabolism. -
Antifungal Agent
2-Desfluoro fluconazole is an azole antifungal agent that functions by inhibiting ergosterol synthesis, disrupting fungal cell membrane integrity. It exhibits broad-spectrum antifungal activity, particularly against various Candida and Cryptococcus species. This compound is valuable for research applications aimed at studying antifungal resistance mechanisms and developing new therapeutic strategies against fungal infections. -
Pesticide
Mansonone E is a natural pesticide derived from the heartwood of Mansonia gagei, with a primary mechanism of antifungal and antibacterial activity. It exhibits significant antifungal efficacy against Cladosporium cucumerinum, Candida albicans, and Phytophthora parasitica. Mansonone E demonstrates potent antibacterial properties, with MIC50 values of 7.8 μg/mL against Xanthomonas oryzae pv. oryzae and X. oryzae pv. oryzicola. Additionally, it possesses antifeedant and herbicidal activities, making it a valuable compound for agricultural and environmental research applications. -
Fungal Inhibitor
2,4′-Dichloroacetanilide is a fungistatic agent that inhibits the growth of fungi by targeting key cellular processes. It demonstrates significant antifungal activity against Trichosporon asteroides, with a minimum inhibitory concentration (MIC) of 6.25 μg/mL. This compound is valuable for research applications involving fungal pathogenesis and the development of antifungal therapies. -
Antibacterial/Antifungal Agent
Cyclo(L-leucyl-L-tryptophyl) is a cyclic dipeptide known for its antibacterial and antifungal properties. It functions as a melatonin receptor agonist, contributing to its diverse biological activities. This reagent is often utilized in studies focusing on microbial inhibition and its potential therapeutic applications in infectious diseases. -
Antibacterial Agent
4-Methylbenzohydrazide is an antibacterial agent that exerts its activity against a range of microbial targets. It demonstrates a potent minimum inhibitory concentration (pMIC) value of 1.38 against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Aspergillus niger. This compound is suitable for research applications focused on developing antibacterial therapies and studying microbial resistance mechanisms. -
Antifungal
Chloramultilide B is a lindenane dimer that exhibits potent antifungal activity. It specifically inhibits the growth of Candida albicans and Candida parapsilosis, demonstrating a minimum inhibitory concentration (MIC) of 0.068 μM. This compound can be utilized in research focused on antifungal treatments and the study of fungal pathogenesis. -
Fungal Inhibitor
Cyclo(Pro-dArg) is a potent chitinase inhibitor, primarily targeting fungal cell wall integrity. It effectively disrupts cell separation in Saccharomyces cerevisiae while having no significant impact on its overall growth. Additionally, Cyclo(Pro-dArg) inhibits the morphological transition of Candida albicans from yeast to filamentous forms, making it valuable for research in fungal biology and antifungal drug development. -
Antifungal Agent
Antifungal agent 112 (Compound 1e) primarily targets fungal pathogens, demonstrating significant antifungal activity against Candida albicans, Aspergillus niger, and Aspergillus fumigatus, with minimum inhibitory concentrations (MIC) of 0.0024, 0.0022, and 0.0028 M, respectively. This compound is valuable for research applications focused on antifungal drug development and the study of fungal infections. Its potent efficacy may contribute to therapeutic strategies against resistant fungal strains. -
Antimicrobial Agent
3-Methoxy-2,5-toluquinone is an antimicrobial agent that exhibits moderate antibacterial and antifungal activity. It has potential applications in the study of infectious diseases and the development of novel therapeutic strategies. This compound serves as a valuable tool for researchers investigating the mechanisms of action of antimicrobial agents in various biological contexts. -
Fungicide
Ethaboxam is a β-tubulin inhibitor that effectively targets and disrupts the microtubule formation in fungi. This compound demonstrates potent anti-oomycete activity, making it a valuable tool in the study of plant-pathogenic fungi. Its mechanism of action provides insight into fungal cell division and offers potential applications in agricultural research and crop protection strategies. -
Antifungal Agent
Nitrofungin (2-Chloro-4-nitrophenol) is an antifungal agent that disrupts fungal cell membrane integrity. Its primary mechanism involves interference with ergosterol synthesis, making it a valuable tool for antifungal research. Nitrofungin is useful in studies focusing on fungal infections and the development of antifungal therapies. Additionally, it is of interest for examining microbial degradation pathways in environmental microbiology. -
Antimicrobial Drug
Somantadine is an antimicrobial agent known for its potent antimicrobial and antifungal properties. It acts by disrupting microbial cell membranes, thereby inhibiting growth and facilitating clearance of infections. This compound is valuable in research settings focused on developing therapies for bacterial and fungal infections. Its effectiveness makes it a significant candidate for studying antimicrobial resistance and evaluating new therapeutic strategies. -
Fungal
(±)-Voriconazole is a potent antifungal agent targeting fungal pathogens. It exhibits broad-spectrum activity against various fungi, including Candida and Aspergillus species, making it valuable in both clinical and research applications. This compound is primarily utilized to study antifungal resistance mechanisms and to explore novel therapeutic strategies for fungal infections. -
Antifungal Agent
Antifungal agent 143 is a potent compound primarily targeting fungal pathogens. This agent exhibits significant antifungal activity against Candida albicans and Aspergillus niger, as well as antibacterial effects against various bacterial strains including Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pyogenes. Antifungal agent 143 is suitable for research applications focused on antimicrobial activity and the development of new therapeutic strategies. -
Antifungal Agent
β-Phenylethyl β-D-glucoside is a phenolic compound that serves as an antifungal agent. It exhibits significant antifungal activity against Candida albicans, making it relevant for the study of fungal infections. This compound can be isolated from the leaves of Piper crocatum and is useful in researching antifungal therapies and mechanisms. -
Immunogen Hapten
Procymidone is an immunogen hapten that serves as a crucial element for the production of polyclonal antibodies when conjugated with carrier proteins such as cOVA. This compound exhibits antifungal activity, making it valuable for research applications in immunology and toxicology, particularly in studies investigating immune responses to chemical haptens and the mechanisms of antifungal action. -
Antifungal Agent
(10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) serves as an antifungal agent and is recognized for its role as a PPARα agonist. Isolated from the basidiomycete Gomphus floccosus, it enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. This compound is suitable for research applications focused on metabolic processes and fungal inhibition. -
Antimicrobial Agent
7-(Carboxymethoxy)-4-methylcoumarin is an antimicrobial agent known for its antibacterial and antifungal properties. It exhibits inhibitory activity against a range of pathogens, including Staphylococcus aureus, Bacillus cereus, Staphylococcus luteus, Candida albicans, Candida glabrata, and Candida parapsilosis. This compound is valuable for research applications targeting microbial infections and studying antimicrobial mechanisms. -
Antifungal Agent
(Z)-Lanoconazole is an imidazole antifungal agent characterized by its Z configuration. It exhibits potent activity against a wide range of fungi, both in vitro and in vivo, by inhibiting sterol 14-alpha demethylase, thus disrupting ergosterol biosynthesis in fungal membranes. This compound is valuable for research into dermatophytosis and onychomycosis, providing insights into fungal infections and therapeutic interventions. -
Fungal Inhibitor
4-Chlorosalicylic acid is a potent fungal inhibitor that functions primarily by inhibiting monophenolase and diphenolase activities, demonstrating IC50 values of 1.89 mM and 1.10 mM, respectively. It exhibits significant antimicrobial properties, displaying an MIC of 250 μg/mL and an MBC of 500 μg/mL against E. coli. This compound is useful in research applications focused on elucidating mechanisms of fungal and bacterial inhibition. -
Aryltetralin Lignans
α-Peltatin is an aryl lignan that exhibits significant anticancer and antifungal properties. It functions primarily by inhibiting DNA topoisomerase, disrupting DNA replication and repair, and by hindering tubulin polymerization, which impairs microtubule formation. These mechanisms make α-Peltatin a valuable compound for research in cancer biology and antifungal assays. -
Fungicidal Activity
Pinosylvin monomethyl ether primarily targets fungal pathogens, exhibiting notable fungicidal activity. This compound demonstrates antibacterial effects, making it of interest for research in microbiology and pharmacology. Its applications include the study of fungal resistance and the development of antimicrobial agents. -
Antifungal Agent
iKIX1 is an antifungal agent that targets the KIX domain of the mediator subunit CgGal11A, interrupting its interaction with the activation domain of CgPdr1. This compound effectively resensitizes drug-resistant Candida glabrata to azole antifungals in vitro, with inhibition constants IC50 and Ki values of 190.2 μM and 18 μM, respectively. iKIX1 is utilized in research focused on understanding multidrug resistance mechanisms and addressing C. glabrata infections. -
Antifungal Agent
Verazine, an antifungal agent derived from the dried roots and rhizoma of Veratrum maackii Regel, targets fungal pathogens effectively. Its mechanism involves inducing DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. This compound is relevant for research applications focusing on fungal infections and neurological diseases, offering insights into their underlying mechanisms. -
Antimalarial/Antifungal Agent
Rutarin is a coumarin derivative that exhibits antimalarial and antifungal properties. It effectively inhibits Plasmodium falciparum, demonstrating an IC50 of 88 μg/mL, making it a potential candidate for malaria research. Additionally, Rutarin shows inhibitory activity against Coniophora cerebella, highlighting its utility in antifungal studies. -
Antifungal Agent
Concanamycin C is an antifungal agent that primarily targets the inhibition of lymphocyte proliferation. This compound demonstrates significant antibiotic activity against various fungal and yeast species, making it a valuable tool in antifungal research. It is particularly useful in studies exploring immune responses and fungal pathogenesis. -
Antifungal Agent
Antifungal agent 49 is an antifungal compound designed to target fungal pathogens. It exhibits potent activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM. This agent can be utilized in research focused on fungal infections and the development of novel antifungal therapies. -
Fungal Inhibitor
(E)-Coniferyl alcohol is a fungal inhibitor that acts as an intermediate in the biosynthetic pathways of eugenol, stilbenoids, and coumarin. This compound demonstrates potent activity against fungal species, making it valuable for studies focused on fungal growth inhibition. Its applications span research on plant defense mechanisms and the development of antifungal agents. -
Antifungal Agent
Diamthazole hydrochloride is an antifungal agent that targets fungal cell membranes. It has demonstrated significant activity against a range of fungal pathogens, making it a valuable tool for infection research. This compound is particularly useful in studying mechanisms of fungal resistance and evaluating potential therapeutic interventions. -
BoNT A Inhibitor
Chaetochromin A is a fungal metabolite that acts as an inhibitor of botulinum neurotoxin serotype A (BoNT A). With an IC50 value of 24.6 μM, it demonstrates significant inhibitory effects, making it a valuable tool for research into neurotoxicology and the mechanistic pathways of neurotoxin action. Its role in understanding BoNT A interactions provides insights for potential therapeutic applications. -
Antimicrobial Agent
Chlorobutanol hemihydrate functions as an antimicrobial agent, demonstrating effectiveness against a range of Gram-positive and Gram-negative bacteria, as well as various fungal spores and fungi. Its preservative properties make it suitable for applications in both the food and cosmetics industries. This compound is valuable for research involving antimicrobial resistance and preservation techniques in different biological contexts.
