Catalog No.
Product Name
Application
Product Information
Citations
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Fungicide and Preservative
Iodopropynyl butylcarbamate (IPBC) is a broad-spectrum fungicide that effectively inhibits fungal growth by targeting key metabolic pathways. It is commonly utilized as a preservative in various applications, including paints, coatings, wood protection, personal care products, and cosmetics. IPBC's strong antifungal properties make it a valuable reagent for researchers studying fungal resistance and preservation techniques in diverse environments. -
Fungicide
Benodanil is a benzanilide fungicide that targets fungal pathogens in various agricultural applications. It exhibits effective antifungal activity, making it a valuable tool in the management of crop diseases. Researchers utilize Benodanil to study its efficacy and mechanisms of action in combating fungal infections in plants, contributing to improved agricultural practices and yield outcomes. -
Antifungal Peptides
Cyclo(L-Phe-trans-4-OH-L-Pro) is a cyclic peptide that exhibits antifungal activity by disrupting the integrity of fungal cell membranes. This compound is valuable in research focused on developing novel antifungal agents and studying the mechanisms of peptide-based antifungal strategies. Its precise mechanism of action makes it a potential candidate for addressing fungal resistance in clinical settings. -
Siderophore
Bacillibactin, a cyclic tricatecholate siderophore, primarily targets iron acquisition in bacteria by chelating iron ions (Fe3+) from the environment. This mechanism enhances bacterial survival under iron-limited conditions and exhibits direct antimicrobial activity against producing strains such as Pseudomonas aeruginosa and Aeromonas veronae, along with plant pathogens like Pseudomonas syringae. Bacillibactin is suitable for use in antibacterial and antifungal research applications, facilitating studies on microbial pathogenesis and iron metabolism. -
Fungal Inhibitor
Kakuol is a naturally derived compound that acts as a fungal inhibitor, targeting fungal cell growth and proliferation. Exhibiting potent antifungal activity, Kakuol is valuable for research applications involving the investigation of fungal infections and the development of antifungal therapies. Its mechanism of action provides insights into novel approaches for combating fungal pathogens. -
SDH Inhibitor
SDH-IN-2 is a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 value of 0.55 μg/mL, demonstrating strong antifungal activity against phytopathogenic fungi, with an average EC50 range of 3.82-9.81 μg/mL. This compound also features an alkyne group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its dual role as an SDH inhibitor and antifungal agent makes SDH-IN-2 a valuable tool for biochemical research and drug development studies focused on metabolic pathways and fungal diseases. -
Fungal Inhibitor
SCH 51048 is a potent fungal inhibitor that generates active metabolites with demonstrated antifungal properties. Research studies have shown that these metabolites exhibit enhanced activity, making SCH 51048 a valuable compound for investigating antifungal mechanisms and evaluating therapeutic options in fungal infections. This compound serves as a useful tool in the study of fungal biology and the development of new antifungal agents. -
Antifungal Agent
4',7-Dimethoxyisoflavone is a naturally occurring isoflavone derived from the leaves of Albizzia lebbeck, exhibiting significant antifungal properties. This compound has been shown to inhibit the growth of various fungal pathogens, making it a valuable reagent for research in antifungal drug development and related studies. Its potential applications extend to investigations focused on the mechanisms of fungal resistance and the exploration of new therapeutic strategies. -
Analogue of Pyrazine-2-carboxamide
Pyrazine-2-amidoxime is a structural analogue of pyrazine-2-carboxamide, primarily targeting microbial organisms. It exhibits significant antimicrobial activity, effectively killing and inhibiting the growth of Candida albicans, a common fungal pathogen, as well as various Gram-positive bacteria. This compound is valuable for research applications focused on antifungal and antibacterial therapies. -
olysaccharide Copolymer
L-Triguluronic acid is a linear polysaccharide copolymer consisting of three L-guluronic acid units. It serves as a precursor to alginate, a class of unbranched polyanionic polysaccharides that exhibits significant biological activities. This compound is particularly useful in research focused on the development of delivery systems for anti-fungal agents, aiding in the exploration of innovative therapeutic strategies. -
Anti-fungal Agent
Rubropunctamine is an antifungal agent derived from the red Monascus pigment. It demonstrates notable antibacterial activity alongside its efficacy against various yeast and filamentous fungi strains. Additionally, Rubropunctamine has been associated with potential embryotoxic and teratogenic effects, highlighting its relevance in toxicological research and the study of fungal infections. -
Antifungal Agent
ME1111 is an antifungal agent that targets succinate dehydrogenase in Trichophyton species. It exhibits significant efficacy against dermatophytes, making it a valuable tool for the study of fungal infections. Additionally, ME1111 demonstrates excellent penetration into human nails, facilitating research applications focused on onychomycosis and related conditions. -
Fungicide
Fenpropidin is a piperidine-based fungicide that primarily targets a variety of fungal pathogens in cereal crops. It exhibits significant antifungal activity against several human pathogenic yeasts and filamentous fungi, making it valuable in both agricultural and medical research applications. This compound is essential for studying fungal resistance mechanisms and evaluating antifungal efficacy. -
Fungal Inhibitor
Picropodophyllone is an aryltetralin lignan that functions as a fungal inhibitor. This compound exhibits significant antifungal activity, making it a valuable tool for research applications in mycology and the study of fungal pathogenesis. Its isolation from the leaves of Podophyllum hexandrum underlines its natural origin and potential therapeutic implications in combating fungal infections. -
Fungal Inhibitor
L-4-Oxalysine hydrochloride is a naturally occurring compound that acts as a fungal inhibitor. Traditionally isolated from the culture media of Streptomyces roseovirdofuscus, this reagent demonstrates significant antitumor activity. It is utilized in research studies focused on fungal pathogenesis and potential therapeutic applications in oncology. -
Bacteriostat
Sulfometuron-methyl is a potent inhibitor of the enzyme acetolactate synthase (ALS), primarily targeting this pathway to exert its herbicidal effects. In addition to its herbicidal applications, sulfometuron-methyl demonstrates significant antibacterial and antifungal properties, effectively inhibiting the activity of Salmonella typhimurium ALS II and Escherichia coli ALS III. This compound is valuable for research in fields related to microbial resistance and herbicide mechanisms. -
Fungicide Agent
Pyribencarb is a benzylcarbamate-class fungicide that functions primarily as a Qo inhibitor of cytochrome b. It demonstrates strong efficacy against various plant pathogenic fungi, particularly Botrytis cinerea and Sclerotinia sclerotiorum. This compound is valuable for research applications aimed at understanding plant-fungal interactions and developing fungal disease management strategies in agriculture. -
Antifungal Agent
Isorhapontin is an antifungal agent that targets Trichoderma cellobiohydrolase I (CBH I), exhibiting an inhibitory constant (Ki) of 57.2 μM. Additionally, Isorhapontin effectively inhibits the activity of Trichoderma endoglucanase I. This compound is valuable for research into antifungal mechanisms and enzyme activity modulation. -
Antifungal Agent
Stilbamidine dihydrochloride is a diamidine compound that functions as an antifungal agent. It exhibits efficacy against a variety of fungal infections through its inhibitory action on fungal cell growth and replication. This reagent is primarily utilized in research applications aimed at elucidating antifungal mechanisms and developing potential therapeutic strategies against fungal pathogens. -
Antifungal Agent
Macrocarpal I is a phloroglucinol-derived sesquiterpenoid that exhibits potent antifungal activity. It demonstrates significant efficacy against Candida glabrata, with an IC50 value of 0.75 μg/mL. Isolated from the juvenile leaves of Eucalyptus maideni, Macrocarpal I serves as a valuable tool for research on fungal infections and the development of antifungal therapies. -
Fungicide
Diclobutrazol is a systemic fungicide that targets fungal phytopathogens, exhibiting strong activity against rusts and powdery mildews. It is utilized in agricultural research for its effectiveness in controlling a variety of crop diseases, making it an essential tool for studying plant-pathogen interactions and developing disease management strategies in crop production. -
Antibiotic
Bikaverin is a natural antibiotic compound derived from various fungal species, known for its distinctive reddish pigment. This reagent exhibits effective antimicrobial activity, specifically targeting certain protozoa and fungi. It is commonly used in research applications focused on the exploration of microbial resistance and the development of novel antimicrobial therapies. -
Fungal Inhibitor
Exalamide is a potent antifungal agent targeting fungal growth through the inhibition of specific enzymes involved in cellular processes. This compound exhibits significant biological activity against a range of fungal pathogens, making it a valuable tool for research on fungal infections and related diseases. Its application is suited for studies focused on antifungal mechanisms and the development of new therapeutic strategies. -
Antibacterial Agent
Deacylketoconazole is an orally active metabolite of ketoconazole, primarily functioning as an antibacterial agent. This compound demonstrates notable antifungal and antibacterial activities, making it relevant in the study of infectious diseases. Additionally, deacylketoconazole exhibits cytotoxic effects in rat hepatocytes, providing insights into its potential impact on liver function. It serves as a valuable tool in research focused on antimicrobial efficacy and cellular toxicity. -
Monoterpene alcohol
Fenchyl alcohol is a monoterpene alcohol known for its antifungal properties. It effectively inhibits the formation of biofilms and hyphae in Candida albicans, making it valuable for studies on fungal infections. Additionally, Fenchyl alcohol demonstrates a significant inhibitory effect on rumen microbial activity in ruminants such as sheep and deer, aiding research in gastrointestinal microbiology. -
Fungal Inhibitor
2-Butylbenzo[d]isothiazol-3(2H)-one is a fungal inhibitor that displays significant antibacterial and antifungal activity. This compound is utilized in agricultural applications to safeguard crops against pathogenic fungi, making it an essential ingredient in pesticides. Additionally, it is incorporated into coatings to deter mold and algae growth. Its preservative properties also make it valuable in personal care formulations, helping to extend product shelf life. -
Antifungal Agent
Sulbentine is an azole antifungal agent that exhibits both fungistatic and fungicidal activities. It serves as a locally acting antimycotic in vivo, making it valuable for treating a range of fungal infections. Sulbentine is commonly utilized in research applications focused on antifungal mechanisms and drug efficacy studies. -
Fungal Inhibitor
2-Ethylnaphthalene is an alkyl-substituted polyaromatic compound that serves as a fungal inhibitor. It has been shown to negatively correlate with the abundance of Glomus species within arbuscular mycorrhizal fungi communities. This property makes 2-Ethylnaphthalene a valuable reagent for investigating fungal interactions and dynamics in various biological research applications. -
SDHI
Penflufen is a potent succinate dehydrogenase inhibitor (SDHI) that targets the mitochondrial respiratory chain. This compound demonstrates broad-spectrum antifungal activity, effectively combating a variety of fungal diseases such as potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanuts. Penflufen is valuable for research applications in plant pathology and agricultural disease management. -
Antifungal Agent
Antifungal agent 18 is an antifungal agent that acts by disrupting fungal cell wall integrity through targeting the unfolded protein response (UPR), calcineurin, and MAPK pathways. It exhibits broad-spectrum antifungal activity against major human fungal pathogens, demonstrating efficacy in both in vitro and in vivo studies. This compound is suitable for research involving invasive fungal pathogens and cutaneous dermatophytes, providing valuable insight into fungal pathogenesis and potential therapeutic interventions. -
Antifungal Agent
4,6-Dimethoxysalicylaldehyde is an antifungal agent that exhibits significant activity against Candida albicans and moderate activity against Saccharomyces cerevisiae. This compound is utilized in research focusing on antifungal mechanisms and potential therapeutic applications for fungal infections. Its unique structure and activity profile make it a valuable tool for studying the efficacy of antifungal treatments. -
Antiacid/Antiulcer Agent
Magnesium silicate primarily acts as an antacid and antiulcer agent. This compound, comprised of magnesium oxide and silicon dioxide, offers effective relief from gastric discomfort and acidity. Additionally, magnesium silicate serves various research applications, including the development of food additives and the exploration of its piezoelectric properties. Its diverse capabilities also extend to use as a deodorant, decolorizing agent, and antifungal agent in biological systems. -
Antifungal Agent
Fosravuconazole L-lysine ethanolate, a prodrug of Ravuconazole, acts as an orally bioavailable broad-spectrum antifungal agent. It demonstrates significant efficacy against various fungal infections, making it a valuable tool for research on candidiasis, onychomycosis, and parasitemia. This compound is instrumental in exploring antifungal therapies and evaluating treatment outcomes in fungal-related diseases. - Lariatins is a novel anti-mycobacterial peptides with a lasso structure produced by Rhodococcus jostii K01-B0171.
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Antiinfective Agent
SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism. -
HIV replication inhibitor
Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus). -
Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against, bacteria, fungi, and protozoa at micromolar concentration.
- Safracin B, a tetrahydroisoquinoline (THIQ) alkaloid, is a naturally occurring antibiotic from Pseudomonas fluorescens. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities.
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Antibiotic
Tigecycline mesylate is a broad-spectrum glycylcycline antibiotic that targets bacterial protein synthesis. It exhibits significant inhibitory activity against various Gram-positive and Gram-negative bacteria, with a mean inhibitory concentration (MIC) for E. coli (MG1655 strain) of approximately 125 ng/mL. For Acinetobacter baumannii, the MIC50 and MIC90 values are 1 mg/L and 2 mg/L, respectively, making it valuable for research focused on antibiotic resistance and infection control. -
HIV NNRTI
(Rac)-Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1. It demonstrates significant antiviral activity with a Ki of 2.93 nM for the inhibition of the wild-type HIV-1 reverse transcriptase and an IC95 of 1.5 nM against HIV-1 replication in cultured cells. This compound is suitable for research applications focusing on HIV-1 therapy and the development of antiretroviral drugs. -
Antibiotic
nTZDpa is a partial agonist of PPARG and functions as an antibiotic. It exhibits significant antibacterial activity, particularly against both growing and persistent strains of Staphylococcus aureus, through the mechanism of lipid bilayer disruption. This compound is valuable for research applications focused on antibiotic resistance and the exploration of novel therapeutic strategies against bacterial infections. -
Antibacterial Agent/Growth-promoting Agent
Quindoxin is an antibacterial agent that acts by disrupting bacterial cell function. It demonstrates significant growth-promoting activity, particularly in livestock, and has been shown to exhibit dose-dependent mutagenicity against Salmonella typhimurium strains TA98 and TA100. Additionally, Quindoxin is associated with potential DNA damage, highlighting its relevance in studies related to genotoxicity and carcinogenicity. -
Bacterial Transcription Inhibitor
GKL003 is a bacterial transcription inhibitor that targets the interaction interface of RNA polymerase (RNAP) and the sigma factor, with a Ki value of 5.79 nM. By specifically binding to the RNAP β' clamp helix region at the σA factor binding site, GKL003 disrupts the formation of the RNAP holoenzyme and inhibits bacterial transcription initiation complexes. This compound effectively inhibits the growth of both Gram-positive and Gram-negative bacterial strains, including those that are drug-resistant, making it a valuable tool for research applications in microbiology and antibiotic resistance studies. -
FXR Antagonist
(-)-(E)-Guggulsterone is a natural stereoisomer of Guggulsterone that functions as a Farnesoid X Receptor (FXR) antagonist with an IC50 of 24.06 μM. This compound exhibits significant hypolipidemic effects and demonstrates the ability to suppress dengue virus (DENV) replication by enhancing antiviral interferon responses through the activation of Nrf2 and upregulation of HO-1 expression. Additionally, (-)-(E)-Guggulsterone displays antibacterial properties against various strains, including Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa, as well as offering cardiac protective and antioxidant benefits in rat models. -
Antibiotic
CPPD-Q is an antimicrobial agent that primarily targets bacterial pathogens. It demonstrates potent antibacterial activity with an EC50 value of 6.98 mg/L against Vibrio fischeri. Additionally, CPPD-Q exhibits insecticidal properties in Caenorhabditis elegans, where it induces the generation of reactive oxygen species (ROS) in the intestines at concentrations of 1 or 10 µg/mL. This compound is suitable for research applications focused on antimicrobial resistance and the mechanisms of insecticidal action. -
Antitumor/ Antibacterial Agent
Epanorin is a secondary metabolite derived from the Acarospora lichenic species, primarily targeting tumor cells and bacterial pathogens. It exhibits potent antitumor activity by inhibiting cancer cell proliferation, reducing reactive oxygen species (ROS) production, and inducing cell cycle arrest in the G0/G1 phase. Additionally, Epanorin demonstrates antibacterial properties, making it valuable for research applications focused on cancer treatment and bacterial infections, including studies on breast cancer and Streptococcus pneumoniae infections. -
Bacterial Inhibitor
N-Butanoyl-L-homoserine lactone (C4-HSL) is a bacterial inhibitor that functions as a signaling molecule in quorum sensing. This compound demonstrates significant antibacterial activity and effectively disrupts biofilm formation, particularly in Pseudomonas aeruginosa. Research applications include studying bacterial communication and developing strategies to combat antibiotic-resistant infections through targeted inhibition of quorum sensing pathways. -
Bacterial Inhibitor
2-Ethyl-6-methylphenol is an alkylphenol with significant antibacterial properties. This compound has demonstrated efficacy in inhibiting bacterial growth and exhibits potential insecticidal activity, making it a valuable tool in microbiological research and pest control studies. Its role as a bacterial inhibitor can facilitate investigations into microbial resistance and the development of novel antimicrobial agents. -
Antibacterial Agent
4-Chloro-2-methylphenol is an antibacterial agent that effectively inhibits bacterial growth through disruption of cell membrane integrity. Its broad-spectrum antimicrobial activity makes it suitable for use in various pharmaceutical applications, particularly as a preservative and excipient in formulations. This compound is also valuable in research settings focused on studying antibacterial mechanisms and developing new antimicrobial therapies. -
Anti-bacterial Agent
Perillene is a natural compound derived from essential oils, primarily recognized for its antibacterial properties. It exhibits significant antibacterial activity against various pathogens, making it a valuable reagent for research in microbial inhibition and infection prevention. Additionally, perillene has been investigated for its potential antitumor effects, contributing to studies focused on cancer therapeutics and natural product research.
