Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Erythromycin hydrochloride is a macrolide antibiotic that acts as a protein synthesis inhibitor, targeting bacterial ribosomes. It demonstrates broad-spectrum activity against both Gram-positive and some Gram-negative bacteria, making it effective in treating various bacterial infections, including respiratory and skin infections. Additionally, erythromycin hydrochloride has been implicated in the inhibition of mammalian mRNA splicing, indicating potential roles in research related to gene expression and cellular function. This compound is widely utilized in biomedical research for its antibacterial properties and mechanisms. -
Anti-HIV Agent
3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog that serves as an anti-HIV agent by acting as a chain terminator. Incorporated into the nascent DNA strand by HIV reverse transcriptase, AZddCTP halts DNA synthesis due to its lack of a 3'-hydroxyl group, effectively inhibiting viral replication. With IC50 values of 15.6 μM against wild-type HIV and 160.8 μM for AZTR HIV, 3′-Azido-2′,3′-dideoxy-CTP demonstrates significant antiviral activity, making it a valuable tool in HIV research. -
Insecticide/Antibacterial Agent
Satranidazole is an orally active insecticide and antimicrobial agent that primarily targets DNA through the formation of reduced nitro intermediates. By inducing helix instability and strand breakage, it exhibits notable antitrichomonal activity against organisms such as Trichomonas vaginalis and Trichomonas foetus, as well as antiamoebic effects in rodent models of hepatic and caecal amoebiasis. Additionally, Satranidazole has been shown to inhibit the replication of bacteriophage φX174 DNA. This compound is valuable for research exploring caecal amoebiasis, trichomoniasis, and anaerobic bacterial infections. -
Anticancer Agent
Endusamycin is an anticancer agent that inhibits protein and nucleic acid synthesis in Ehrlich ascites carcinoma cells. This selective activity contributes to its efficacy as a potential therapeutic for cancer research, while exhibiting no antibacterial or antifungal effects. Endusamycin is suitable for studies aimed at understanding cancer cell metabolism and the development of new cancer treatment strategies. -
FgGpmk1 Inhibitor
FgGpmk1-IN-1 is a selective inhibitor of the Fusarium graminearum mitogen-activated protein kinase (FgGpmk1), exhibiting an EC50 value of 3.46 μg/mL. This compound is valuable for investigating the biological role of FgGpmk1 in fungal pathogenesis and offers potential applications in the study of plant-fungal interactions. Researchers can utilize FgGpmk1-IN-1 to explore therapeutic strategies against Fusarium-related diseases. -
Heterocyclic Compound
Indazole, a heterocyclic aromatic compound, exhibits significant biological activity through its diverse derivatives. These derivatives are known for their anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal, and antitumor properties. Indazole and its derivatives are valuable tools for research into cancer, neurological disorders, cardiovascular diseases, and gastrointestinal diseases, highlighting their potential in various therapeutic applications. -
Antibiotic
Luisol A is an anthraquinone antibiotic analog derived from an aromatic tetraol, recognized as a major metabolite of Streptomyces, a marine actinomycete. This compound exhibits significant antibacterial activity, making it a valuable tool in the study of antibiotic mechanisms and resistance. Its application in research aids in the exploration of novel antimicrobial agents and their effects on various bacterial strains. -
Bacterial Inhibitor
Aniline-MPB-amino-C3-PBD is a cytotoxic agent targeting bacterial cells through minor-groove binding of DNA. This sequence-selective compound serves as an effective payload for antibody-drug conjugates (ADCs), enhancing their therapeutic efficacy. Its antimicrobial properties make it a valuable tool for research in bacterial inhibition and related applications. -
Antibiotic
Agrochelin is an alkaloid antibiotic with cytotoxic properties, derived from the fermentation of marine Agrobacterium species. This compound exhibits significant cytotoxic activity against various tumor cell lines, making it a valuable tool in cancer research. Agrochelin's mechanism of action may provide insights into antibiotic efficacy and the development of novel therapeutic strategies for oncological applications. -
Bacterial Inhibitor
Py-MPB-amino-C3-PBD is a cytotoxic agent that functions as a bacterial inhibitor. This compound serves as a payload for antibody-drug conjugates (ADCs) and exhibits significant antimicrobial activity. Its unique structure, characterized by a non-alkylating group, makes it a valuable tool for research applications aimed at targeting bacterial infections and developing therapeutics in the field of microbiology. -
Antibiotic Agent
Polyketomycin is a tetracyclic quinone glycoside antibiotic derived from Streptomyces sp. or Streptomyces diastatochromogenes, targeting Gram-positive bacteria with a minimal inhibitory concentration (MIC) of less than 0.2 µg/mL. This compound exhibits notable antibacterial, anticancer, and antimalarial activities, making it a valuable tool in microbiological and pharmacological research. Its diverse biological applications support investigations in antibiotic efficacy, cancer treatment, and antimalarial drug development. -
Antitumor Antibiotic
Sandramycin is a cyclic depsipeptide antibiotic with a primary mechanism of action as an antitumor agent. It exhibits potent DNA intercalation and binding, functioning effectively as a cytotoxin in antibody-drug conjugates (ADCs). Sandramycin demonstrates significant activity against Gram-positive bacteria and is recognized for its strong antitumor efficacy, making it a valuable reagent for cancer research and the development of targeted therapies. -
Dengue Protease Inhibitor
Carbonic anhydrase inhibitor 16 is a potent dengue protease inhibitor that targets human carbonic anhydrases I and II, exhibiting inhibitory constants (Ki) of 28.5 nM and 2.2 nM, respectively. This compound demonstrates significant biological activity in hindering dengue virus replication by disrupting protease function. It may be utilized in research applications aimed at elucidating mechanisms of dengue virus pathogenesis and developing antiviral therapeutics. -
Bacterial Inhibitor
Procodazole is a potent bacterial inhibitor that enhances immune response, offering protection against various viral and bacterial infections. In addition to its broad-spectrum antibacterial effects, Procodazole demonstrates antiparasitic activity and serves as a carbonic anhydrase inhibitor, contributing to its antitumor properties. This compound is suitable for research applications focused on infectious diseases and cancer biology. -
Nucleoside Antibiotic
Dealanylascamycin is a nucleoside antibiotic that functions as a carbonic anhydrase (CA) inhibitor, exhibiting Ki values of 167, 65.2, 234, and 143 nM for human CA isoforms I, II, IV, and IX, respectively. This compound demonstrates broad-spectrum antibacterial activity, notably effective against pathogens such as Xanthomonas citri with a minimum inhibitory concentration (MIC) of 0.4 μg/mL. Additionally, Dealanylascamycin displays significant cytotoxicity, making it a substance of interest for various biological research applications, particularly in the study of antimicrobial effects and CA inhibition. -
HIV Inhibitor
ZL0580 is an HIV inhibitor that functions by selectively binding to the BD1 domain of BRD4, leading to epigenetic suppression of the virus. This compound effectively inhibits Tat transactivation and transcription elongation while promoting a repressive chromatin structure at the HIV promoter. ZL0580 is valuable for research applications focused on HIV therapies and the mechanisms of viral transcription regulation. -
HIV-1 LRA
UMB-136 is a bromodomain inhibitor targeting HIV-1 latency. It serves as a promising latency-reversing agent (LRA) for the eradication of HIV-1, effectively reactivating the virus in various cell models. UMB-136 enhances HIV-1 transcription and promotes viral production by facilitating the release of P-TEFb, thereby contributing to research in HIV treatment strategies. -
Recombinant Bacterial Clones Chromogenic Substrate
X-GalNAc is a chromogenic substrate that specifically targets N-acetyl-β-galactosidase. This reagent is utilized in molecular biology to detect the presence of cloned DNA inserts in bacterial colonies cultured on agar plates. The enzymatic hydrolysis of X-GalNAc results in a distinct color change, facilitating easy identification of recombinant bacterial clones in various genetic research applications. -
Bacterial Inhibitor
Resazurin sodium is a non-toxic, stable redox indicator that targets bacterial activity through its membrane-permeable properties. It serves as a vital tool for assessing cell viability, proliferation, and toxicity in various cell types, including human, plant, animal, bacterial, and fungal cells. Upon reduction, Resazurin sodium transforms into Resorufin, a highly fluorescent compound, enabling sensitive detection and quantification of cellular processes under fluorescent microscopy or spectrophotometry. -
Antibacterial Agent
ANS ammonium is a potent antibacterial agent that also serves as a textile dye. It functions as a fluorescence probe, enabling the detection of various biological interactions. Additionally, ANS ammonium is known to inhibit the binding of triiodothyronine to thyroxine binding globulin, making it useful in radioimmunoassays for triiodothyronine analysis. -
Bacterial Inhibitor
4-Methylherniarin, a coumarin derivative, exhibits antibacterial activity by effectively inhibiting both gram-positive and gram-negative bacterial strains. It demonstrates significant antimicrobial efficacy against B. subtilis and S. sonnei, with IC50 values of 11.76 μg/ml and 13.47 μg/ml, respectively. This compound serves as a valuable tool for research applications focused on combating bacterial infections and elucidating mechanisms of action in microbial resistance. -
Phytoestrogen
3,7-Dihydroxyflavone is a flavonoid phytoestrogen that modulates estrogen receptors, making it a valuable compound for research in hormonal signaling pathways. It serves as an inhibitor of the human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase, demonstrating redox inhibitory activity with IC50 values of 0.6 μM and 6.0 μM, respectively. Additionally, 3,7-Dihydroxyflavone exhibits fluorescence properties, acting as a binding substrate for human serum albumin with specific excitation and emission wavelengths, rendering it useful for biochemical assays and studies related to protein binding interactions. -
Bacterial Metabolite
12-Tridecenoic acid is a bacterial metabolite that plays a crucial role in the regulation of lipid metabolism. It promotes the expression of acetyl-CoA carboxylase α (ACC) while inhibiting carnitine palmitoyltransferase 1A (CPT1A), contributing to the development of hepatic steatosis. This compound is relevant for research in metabolic diseases and cellular lipid regulation. -
Antibacterial Agent
Metioprim is a competitive inhibitor of bacterial dihydrofolate reductase (DHFR), targeting critical pathways in bacterial folate metabolism. It exhibits potent antibacterial activity against anaerobic bacteria and demonstrates synergistic effects when combined with DDS against E. coli and various mycobacterial strains. This reagent is valuable for antibacterial research and development, particularly in studies focused on antibiotic resistance and the efficacy of combination therapies. -
Antibacterial Agent
AR-102 is an antibacterial agent that exhibits potent inhibitory activity against Staphylococcus aureus. It demonstrates competitive inhibition of the F98Y mutant dihydrofolate reductase (DHFR) with a Ki value of 0.22 nM. Structural studies have characterized AR-102 as forming a ternary complex with NADPH in both wild-type and TMP-resistant F98Y mutant S. aureus DHFR, making it a valuable compound for research on antibacterial resistance mechanisms. -
Bacterial Inhibitor
N-Butanoyl-L-homoserine lactone (C4-HSL) is a bacterial inhibitor that functions as a signaling molecule in quorum sensing. This compound demonstrates significant antibacterial activity and effectively disrupts biofilm formation, particularly in Pseudomonas aeruginosa. Research applications include studying bacterial communication and developing strategies to combat antibiotic-resistant infections through targeted inhibition of quorum sensing pathways. -
Bacterial Inhibitor
2-Ethyl-6-methylphenol is an alkylphenol with significant antibacterial properties. This compound has demonstrated efficacy in inhibiting bacterial growth and exhibits potential insecticidal activity, making it a valuable tool in microbiological research and pest control studies. Its role as a bacterial inhibitor can facilitate investigations into microbial resistance and the development of novel antimicrobial agents. -
Antibacterial Agent
4-Chloro-2-methylphenol is an antibacterial agent that effectively inhibits bacterial growth through disruption of cell membrane integrity. Its broad-spectrum antimicrobial activity makes it suitable for use in various pharmaceutical applications, particularly as a preservative and excipient in formulations. This compound is also valuable in research settings focused on studying antibacterial mechanisms and developing new antimicrobial therapies. -
Anti-bacterial Agent
Perillene is a natural compound derived from essential oils, primarily recognized for its antibacterial properties. It exhibits significant antibacterial activity against various pathogens, making it a valuable reagent for research in microbial inhibition and infection prevention. Additionally, perillene has been investigated for its potential antitumor effects, contributing to studies focused on cancer therapeutics and natural product research. -
Antibacterial agent
Gypsogenic acid is a triterpenoid acid with established antibacterial properties, primarily targeting oral bacterial pathogens. It has demonstrated effective minimum inhibitory concentration (MIC) values ranging from 50 to 200 μg/mL against Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans, and Streptococcus sobrinus. Additionally, Gypsogenic acid has been shown to induce blood cortisone cleavage in isolated mice, with an IC50 of 56.6 μM, making it a promising candidate for further research in antibacterial and trypanoidal applications. -
Antibacterial Agent
Antibacterial agent 265 is a potent antibacterial compound targeting various bacterial strains. It exhibits significant activity against both gram-positive organisms such as Staphylococcus aureus, Micrococcus luteus, and Bacillus subtilis, as well as gram-negative bacteria including Escherichia coli, Pseudomonas aeruginosa, and Flavobacterium devorans. This compound is valuable for research applications related to infection control, antimicrobial resistance, and the development of new antibacterial therapies. -
Bacterial Inhibitor
Upleganan is a polymyxin analogue that functions as a bacterial inhibitor, exhibiting antibiotic activity against multidrug-resistant Gram-negative pathogens. It demonstrates significant efficacy, with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. Upleganan is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Bacterial Inhibitor
Gepotidacin (S enantiomer) is a potent bacterial inhibitor that targets bacterial DNA replication and transcription processes. This compound exhibits effective antimicrobial activity against a range of gram-positive and gram-negative bacteria, making it valuable for research in infectious disease models. Its mechanism of action involves inhibition of bacterial topoisomerase, contributing to its bactericidal effects. Gepotidacin (S enantiomer) is primarily applied in studies focused on antibiotic resistance and the development of new therapeutic strategies. -
Antibiotic Adjuvant
PA3552-IN-1 is an antibiotic adjuvant that enhances the efficacy of Polymyxin B against multidrug-resistant Pseudomonas aeruginosa, specifically the DK2 strain. By reducing the expression of the PA3552 gene, PA3552-IN-1 restores bacterial sensitivity, making it a valuable tool for overcoming antimicrobial resistance. This compound is relevant for research applications aimed at developing strategies for treating resistant bacterial infections. -
Bacterial Inhibitor
Griselimycin is a cyclic lipopeptide that functions as a bacterial inhibitor by specifically binding to the sliding clamp of bacterial DNA polymerase, while exhibiting no interaction with human proliferating cell nuclear antigen (PCNA). This compound demonstrates potent antibacterial activity against Mycobacterium tuberculosis, including drug-resistant strains, and various Gram-negative bacteria. Griselimycin is useful in research applications focused on bacterial DNA replication and the development of new antibacterial therapeutics. -
Anti-Candida Agent
Antibacterial Agent 27 is a potent anti-Candida agent that targets the growth and proliferation of Candida species. This compound exhibits significant antifungal activity, making it a valuable tool for research in fungal infections and therapeutic development. Its efficacy against a range of Candida strains supports investigations into potential treatments for candidiasis and related diseases. -
Antibacterial Drug
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone is a member of the N-Acyl homoserine lactone (AHL) family derived from V. alginolyticus strains. This compound demonstrates significant antibacterial activity and plays a crucial role in biofilm formation. Its unique properties make it valuable for studying bacterial communication and quorum sensing mechanisms in various research applications. -
Antibacterial Agent
IPrAgCl is an antibacterial agent with demonstrated antiproliferative activity. It exhibits an IC50 of 30 nM against the MCF7 cell line and 35 nM against the KB cancer cell line. Additionally, IPrAgCl induces apoptosis in the HL60 cell line through the translocation of apoptosis-inducing factor from the mitochondria to the nucleus, making it a valuable tool for research in cancer and antibacterial studies. -
Sulfonamide Antibiotic
Sulfadimethoxine-d4 is a deuterium-labeled sulfonamide antibiotic, derived from sulfadimethoxine. This compound exhibits broad-spectrum antimicrobial activity and is utilized in the treatment of various infections, including respiratory, urinary tract, enteric, and soft tissue infections. Sulfadimethoxine-d4 serves as a valuable tool in pharmacokinetic studies and metabolic research involving sulfonamide antibiotics. -
Antibacterial Agent
Macrocarpal A, a potent antibacterial agent derived from the leaves of Eucalyptus macrocarpa, exhibits significant antimicrobial activity. It effectively inhibits the growth of Bacillus subtilis PCI219 with a minimum inhibitory concentration (MIC) of below 0.2 µM, and Staphylococcus aureus FDA209P, with an MIC of 0.4 µM. This compound is valuable for research applications focused on antibacterial efficacy and the development of antimicrobial agents. -
Bacterial Inhibitor
Ganoderol A is a terpenoid derived from Ganoderma lucidum that acts as a bacterial inhibitor. It demonstrates antimicrobial properties and plays a role in inhibiting the cholesterol synthesis pathway. Additionally, Ganoderol A exhibits significant anti-inflammatory effects and provides protection against ultraviolet A (UVA) damage, making it valuable for research in microbial resistance and skin protection strategies. -
Antibacterial Agent
4-Heptyloxyphenol functions as an antibacterial agent, exhibiting significant activity against periodontal pathogens such as Porphyromonas gingivalis, Streptococcus artemidis, and Streptococcus sobrinus, with minimum inhibitory concentrations (MIC) of 0.10, 0.21, and 0.14 mM, respectively. This compound is useful in scientific research focused on oral microbiology and the development of novel antibacterial therapies targeting oral pathogens. -
Antibacterial Agent
Antibacterial Agent 26 is a potent antibacterial compound targeting a wide range of bacterial pathogens. With strong activity against both Gram-positive and Gram-negative bacteria, it is suitable for various research applications including studies on antimicrobial resistance and drug efficacy. This compound is valuable for researchers investigating novel antibacterial strategies and mechanisms of action. -
Bacterial Inhibitor
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol with antibacterial properties. It functions by inhibiting bacterial growth, making it valuable for research in antimicrobial applications. Its isolation from Ailanthus altissima Swingle highlights its natural origins and potential utility in studies exploring microbial resistance and antibiotic development. -
Antibacterial Agent
Effusanin A is a natural antibacterial agent derived from Isodon rugosus. It demonstrates potent DNA-damaging activity alongside its antibacterial properties, making it a valuable compound for research into microbial resistance and cellular responses to DNA damage. Its unique biological profile positions Effusanin A as a significant tool for studying the mechanisms of bacterial pathogenicity and developing new antibacterial therapies. -
Antibacterial Agent
Tunicamycin V is a nucleoside natural product that functions as an antibacterial agent by inhibiting bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY), with an IC50 of 0.35 μM. This compound demonstrates significant antibacterial activity, making it valuable for research applications in microbial resistance and antibiotic development. Its mechanism of action highlights its potential for further exploration in the field of antibacterial drug discovery. -
Antibacterial Agent
LolCDE-IN-4 is an antibacterial agent that targets the LolCDE complex, inhibiting its function and disrupting the release of lipoproteins from the inner membrane. It demonstrates antibacterial activity against gram-negative bacteria, including Escherichia coli and Haemophilus influenzae, with a minimum inhibitory concentration (MIC) range of 0.25 to 32 µg/ml. This compound is valuable for research focused on developing new antibacterial therapies and understanding the mechanisms of bacterial resistance. -
Antibacterial/Antiinflammatory Agent
AN0128 is a boron-containing antibacterial and anti-inflammatory agent that targets bacterial infections. It demonstrates significant antimicrobial activity against Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes, and Bacillus subtilis, with minimum inhibitory concentration (MIC) values of 1, 0.5, 0.3, and 1 µg/mL, respectively. AN0128 is suitable for research applications focused on periodontal diseases and various cutaneous disorders. -
Antibacterial Agent
Olanexidine is an antibacterial agent that exhibits activity against a broad spectrum of bacteria, including both Gram-positive and Gram-negative strains. Additionally, it possesses antiseptic properties, making it suitable for various applications in the research of infection and inflammation. Olanexidine's efficacy against diverse microbial threats enhances its utility in studies focused on antimicrobial resistance and therapeutic interventions. -
Antibacterial Agent
Chrysophanol tetraglucoside is recognized for its antibacterial properties, targeting bacterial cell processes to inhibit growth. This compound also exhibits anti-hypolipidemic activity, making it a valuable reagent in research focused on lipid metabolism and microbial infection studies. Its multifunctional nature supports various applications in pharmacological investigations and natural product research.
