-
Antibacterial agent
Clorofene (2-Benzyl-4-chlorophenol) is an aryl halide with significant antibacterial activity. It serves as a broad-spectrum disinfectant, commonly utilized in cleaning and disinfection solutions, as well as in soap formulations. Despite its effectiveness, Clorofene is recognized for its potential carcinogenic properties, warranting cautious application in research involving antibacterial agents. -
Antibacterial Agent
Sapienic acid is a fatty acid with antibacterial properties primarily targeting various Gram-positive and Gram-negative bacteria. It exhibits significant antimicrobial activity against skin and oral cavity pathogens, including Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum, with minimum bactericidal concentration (MBC) values of 31.3 μg/mL, 375.0 μg/mL, and 93.8 μg/mL, respectively. This compound is particularly useful in research applications focused on skin microbiome dynamics and oral health. -
Antibacterial Agent
Antibacterial Agent 68 is an effective antibacterial compound targeting drug-resistant Escherichia coli. This agent demonstrates potent antibacterial activity against multidrug-resistant strains at low concentrations, with an effective dose as low as 0.007 mM. Its low cytotoxicity makes it a valuable tool for researching novel treatments for bacterial infections, particularly in the context of rising antibiotic resistance. -
Antibacterial Agent
Antibacterial Agent 41 is an antibacterial compound targeting bacterial growth and survival. It demonstrates significant antimicrobial activity and is primarily utilized in research focused on developing new antibacterial therapies. Its effective mechanism makes it a valuable tool for exploring novel treatments against resistant bacterial strains. -
Bacterial Inhibitor
Ro 24-6392 is an ester-linked co-drug that combines Ciprofloxacin and Desacetylcefotaxime, targeting inhibition of bacterial growth. It demonstrates potent antibacterial activity against a range of aerobic bacteria in vitro, making it a valuable tool for microbiological research and studies focused on bacterial resistance mechanisms. This compound can be utilized in the development of novel antibacterial therapies and for evaluating bacterial susceptibility to co-drug formulations. -
Antibacterial Peptide
RT2 is a tryptophan-rich cationic amphipathic antibacterial peptide that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. It binds to LPS and interacts with cytoplasmic membrane phospholipids, which facilitates rapid penetration of the bacterial cell membrane. Once inside, RT2 binds to cytoplasmic components, including DNA, to exert potent antibacterial activity. This peptide shows promise for research into acute and chronic infections caused by planktonic bacteria. -
Bacterial Inhibitor
Apalcillin is a bacterial inhibitor designed to target and disrupt the activity of various gram-negative bacteria, particularly those that produce β-lactamase. In combination with Ro 48-1220, a β-lactamase inhibitor, Apalcillin exhibits broad-spectrum activity, effectively inhibiting strains such as Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with minimum inhibitory concentrations as low as 11 μg/mL. This combination also shows significant effectiveness against Pseudomonas aeruginosa and Stenotrophomonas maltophilia at even lower MICs (0.25 to 4 μg/mL). However, its efficacy against certain gram-positive organisms remains limited, making it a valuable tool for research on β-lactamase resistance. -
Antimicrobial
17-Hydroxyventuricidin A is an antimicrobial agent known for its inhibitory effects on specific filamentous fungi, including Verticillium dahliae and Fusarium spp., as well as the Candida tropicalis strain R2 CIP203. This compound demonstrates significant antifungal activity, making it a valuable tool for research in mycology and antifungal compound development. Its mechanism of action and efficacy position it as a potential candidate for further studies in combatting fungal infections. -
Antibacterial Agent
HC2210 is an antibacterial agent that targets Mycobacterium abscessus (Mab), demonstrating an EC50 of 0.72 µM. This compound modulates the expression of Mab genes associated with oxidative stress and lipid metabolism. HC2210 is useful for investigations into Mab infections, contributing to the understanding of bacterial resistance mechanisms and potential therapeutic strategies. -
Antimicrobial Agent
Cleroindicin F, also known as (-)-Rengyolone, is a potent antimicrobial agent. It exhibits significant anticandidal activity against various strains of Candida, demonstrating a minimum inhibitory concentration (MIC) as low as 12.5 µg/mL. This compound is valuable for research applications focused on antifungal therapeutics and microbial resistance studies. -
Bacterial Inhibitor
Phenyl(9H-purin-6-yl)amine is an antibacterial compound that targets bacterial growth by inhibiting various cellular processes. This reagent exhibits significant antibacterial activity and is useful in the development of novel antibacterial agents. Its potential inhibitory effects make it a valuable tool for medical research focused on combating bacterial infections. -
Antibacterial Drug
Multicaulisin is a Diels-Alder type adduct derived from the roots of Morus multicaulis, targeting antibacterial activity. It exhibits potent efficacy against Staphylococcus aureus, including MRSA isolates, highlighting its potential application in research focused on combating MRSA infections. This compound serves as a valuable tool for investigating new antibacterial therapies. -
Bacterial Inhibitor
Radicinol is a bacterial inhibitor derived from the metabolite of Cochliobolus lunata. It demonstrates potent antimicrobial activity, particularly against various strains of bacteria, making it a valuable tool for research in microbiology and drug development. Radicinol can be utilized to study bacterial resistance mechanisms and assess the efficacy of new antibacterial agents. -
Bacterial Inhibitor
Trimethylsilyl-L-(+)-rhamnose acts as a bacterial inhibitor through its structural similarity to natural rhamnose, playing a crucial role in the study of bacterial cell wall composition. This modified sugar is utilized to investigate the biological functions associated with bacterial growth, providing insights into mechanisms of resistance. Researchers can leverage Trimethylsilyl-L-(+)-rhamnose to enhance understanding of bacterial physiology and the implications for antibiotic development. -
Antibacterial Peptide
Penta lysine is an antibacterial peptide that effectively targets multiple bacterial strains including E. coli, A. baumannii, P. aeruginosa, S. aureus, and B. subtilis. Its minimum inhibitory concentration (MIC) ranges from 1.1 to 18 μM, demonstrating significant antimicrobial activity. Penta lysine is valuable for research applications focused on developing new antibacterial therapies and understanding microbial resistance mechanisms. -
Bacterial Inhibitor
Urechistachykinin II is a tachykinin-related peptide (TRP) derived from echiuroid worms, primarily targeting bacterial pathogens. This compound exhibits significant antimicrobial activity while demonstrating a lack of hemolytic effect, making it a valuable tool in the study of bacterial inhibition. Its unique properties may support research in microbial resistance and novel antimicrobial strategies. -
Bacterial Inhibitor
1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine (21:0 PC) functions as a surfactant with notable antibacterial properties. It exhibits efficacy by acting in mucus to inhibit the dissemination of pathogens. Additionally, 1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine contributes to the stability of biofilms, supporting the overall health of associated organisms. This compound is applicable in studies focused on bacterial inhibition and biofilm dynamics. -
Antibacterial Agent
Antibacterial Agent 35 is an antibacterial compound that enhances the efficacy of Ceftazidime by significantly lowering its minimum inhibitory concentration (MIC) value. This synergy suggests its potential role in combating resistant bacterial strains. Antibacterial Agent 35 is suitable for research applications focused on antibiotic susceptibility and the development of combination therapies. -
Antibacterial Compound
Viroxocin is a diterpenoid with antibacterial properties. Isolated from the roots of Salvia viridis L. cvar. Blue Jeans, Viroxocin exhibits weak antibacterial activity, making it a candidate for research in antimicrobial studies. This compound can be utilized to explore its potential effects in drug development and infectious disease research. -
Anti-mycobacterial Agent
Calpinactam (FKI-4905) is a fungal metabolite with potent anti-mycobacterial activity. It selectively inhibits the growth of Mycobacterium species, specifically demonstrating minimum inhibitory concentration (MIC) values of 0.78 μg/ml against Mycobacterium smegmatis and 12.5 μg/ml against Mycobacterium tuberculosis. This compound is primarily utilized in research applications focused on developing treatments for mycobacterial infections. -
Antibacterial Agent
Antibacterial Agent 12 is a biaryloxazolidinone analogue that targets bacterial ribosomes to inhibit protein synthesis. This compound exhibits potent antibacterial activity against both antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria. It is suitable for research applications aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 219 is an antibacterial compound that disrupts cell wall biosynthesis. It demonstrates potent activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with a minimum inhibitory concentration (MIC) ranging from 0.5 to 32 µg/mL, as well as Enterococcus faecium and S. aureus, both with an MIC of 2 µg/mL. This compound is valuable for research related to antibiotic resistance and the development of new antibacterial therapies. -
Bacterial Inhibitor
Antibacterial Agent 240 (compound 62-7c) is a bacterial inhibitor specifically designed to target multidrug-resistant (MDR) strains of Methicillin-resistant Staphylococcus aureus (MRSA). This compound demonstrates significant antibacterial efficacy, as evidenced by its potent anti-infection activity in preclinical mouse models of pneumonia and wound infections caused by MRSA. Its favorable biosafety profile further supports its potential use in therapeutic applications against resistant bacterial infections. -
Antibacterial Agent
Dodicin hydrochloride is a potent antibacterial agent targeting a wide range of microbial organisms. Known for its broad-spectrum antimicrobial activity, it is utilized in various research applications focused on infection control and the development of disinfectants. This compound is suitable for studies exploring mechanisms of antibacterial action and evaluating efficacy against resistant strains. -
Bacterial Penicillin-binding Protein (PBPs) Inhibitor
J-114870 is an inhibitor of bacterial penicillin-binding proteins (PBPs), demonstrating significant efficacy against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS). This compound is valuable for research applications focused on bacterial infections, particularly in understanding resistance mechanisms and developing new therapeutic strategies. -
Bacterial Inhibitor
Antistaphylococcal agent 2 is a bacterial inhibitor targeting Staphylococcus species. It exhibits potent antimicrobial activity, making it effective in combating staphylococcal infections. This compound is primarily utilized in research applications aimed at understanding and developing therapies for bacterial resistance and infection control. -
Antibacterial Agent
Antibacterial Agent 290 is a sulfonamide derivative known for its primary mechanism as an antibacterial agent. This compound exhibits antiproliferative activity against a range of tumor cells and significantly activates the E3 ligase Parkin, inducing auto-ubiquitination with an EC50 of 0.4 μM. Antibacterial Agent 290 is applicable in the synthesis of building blocks for supramolecular structures, including metal-organic frameworks and coordination polymers. Its utility extends to research in cancer, neurological disorders, and infectious diseases. -
Antibacterial Agent
Lucidin ω-ethyl ether is an anthraquinone metabolite that exhibits antibacterial activity by targeting the bacterial cell structure. Isolated from the root of Prismatomeris filamentosa, it demonstrates efficacy against both Gram-positive and Gram-negative bacteria. This compound is useful for research applications in microbial studies and the development of antibacterial agents. -
Antibacterial Agent
L-693989 is an orally active water-soluble lipopeptide that functions as an antibacterial agent. It exhibits significant anticandidal and antipneumocystis activity, effectively preventing the development of P. carinii cysts. This compound shows promise for research applications related to P. carinii pneumonia, contributing to studies focused on combating opportunistic infections. -
Anti-bacterial Agent
Talaromycesone A is an oxaphenalenone dimer with significant antibacterial properties, exhibiting an IC50 of 3.70 μM against Staphylococcus strains pathogenic to humans. Additionally, it demonstrates strong inhibition of acetylcholinesterase with an IC50 of 7.49 μM. This compound is valuable for research applications focusing on antimicrobial susceptibility and neuropharmacology. -
Antibacterial Agent
Antibacterial Agent 52 functions as a broad-spectrum antibacterial agent. It exhibits significant inhibitory activity against various bacterial strains, showcasing potential for studying bacterial resistance mechanisms and evaluating new therapeutic strategies. This compound is suitable for applications in microbiological research and drug development aimed at combating bacterial infections. -
Bacterial Inhibitor
Antibacterial agent 31 is a bacterial inhibitor that demonstrates significant antibacterial activity against rice bacterial leaf streak. This compound is essential for research applications focused on plant pathology and the development of disease-resistant agricultural practices. Its mechanism of action provides insights into bacterial resistance mechanisms and potential strategies for crop protection. -
Antibacterial Agent
3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside is a phenylpropanoid glycoside known for its antibacterial properties. Isolated from the dragon’s blood of Dracaena cambodiana, this compound demonstrates significant activity against various bacterial strains. It serves as a valuable research tool for studies focused on antibacterial mechanisms and the development of antimicrobial agents. -
Antibacterial Agent
Rosellichalasin is an antibacterial agent derived from the endophytic fungus Aspergillus flavipes Y-62. It demonstrates significant antibacterial activity, making it a valuable compound for research in antibacterial applications and the study of microbial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 50 is an effective antibacterial compound primarily targeting Gram-negative bacteria. It exhibits minimum inhibitory concentration (MIC) values of 32 mcg/mL, 64 mcg/mL, and 128 mcg/mL against various Escherichia coli strains, including NCTC 13351, M 50, and 7 MP. This agent is relevant for research applications focused on evaluating antibacterial efficacy and mechanisms of resistance in bacterial pathogens. -
Antibacterial Agent
Antibacterial Agent 54 functions primarily as an antibacterial agent, exhibiting effective inhibition of bacterial growth. This compound is derived from natural sources and offers robust activity against a range of pathogenic bacteria. Its application in research includes the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
Antibacterial agent 249 is a bacterial inhibitor that exhibits broad-spectrum antimicrobial properties. It effectively inhibits the growth of various pathogens including Aspergillus niger, Bacillus subtilis, Pseudomonas albicans, Escherichia coli, and Staphylococcus aureus. Additionally, it displays anti-inflammatory activity in vitro, highlighting its potential applications in the treatment of bacterial infections. -
Antibacterial Agent
2',3'-Dehydrosalannol is a potent antibacterial agent that exhibits strong activity against a range of bacteria including Klebsiella pneumoniae ATCC 13883, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25922, Escherichia coli ATCC 11775, and Enterococcus faecalis ATCC 10541. It displays minimum inhibitory concentration (MIC) values of 0.78, 1.56, 1.56, 6.25, and 25 μg/mL, respectively. This compound is valuable for research applications focusing on antibacterial drug development and microbiological studies. -
Antibacterial Agent
Antibacterial Agent 38 is a novel antibacterial compound that selectively targets bacterial pathogens. It exhibits significant antimicrobial activity, making it suitable for research on bacterial infections and the development of new therapeutic strategies. This compound represents a promising tool for investigating the mechanisms of bacterial resistance and evaluating the efficacy of antimicrobial agents. -
Anti-Bacterial Agent
Rhodirubin B is an anti-bacterial agent primarily targeting Gram-positive bacteria and exhibiting activity against Mycobacterium species. This compound has demonstrated the ability to enhance survival rates in mice inoculated with leukemia L-1210, indicating potential applications in cancer research and infectious disease studies. Rhodirubin B is valuable for investigating mechanisms of bacterial resistance and the interplay between infection and cancer. -
Bacterial Inhibitor
Kipukasin D is a natural nucleoside derived from Aspergillus versicolor, exhibiting potent antibacterial activity. It operates primarily as a bacterial inhibitor, making it valuable for research involving bacterial infections and microbial resistance mechanisms. This compound is useful for studies in pharmacology, microbiology, and drug development focused on identifying new antimicrobial agents. -
Bacterial Inhibitor
Antistaphylococcal agent 3 is a bacterial inhibitor that targets Staphylococcus species, disrupting their growth and proliferation. This compound exhibits potent antimicrobial activity, making it suitable for research applications focused on bacterial infection models and therapeutic development. Its efficacy against resistant strains renders it valuable for studies aimed at understanding staphylococcal pathogenesis and developing novel antibacterial strategies. -
Anti-Bacterial Agent
Rhodirubin A is an anti-bacterial agent primarily targeting Gram-positive bacteria and demonstrating efficacy against Mycobacterium species. In addition to its antibacterial properties, Rhodirubin A has been shown to extend the survival time in mice models inoculated with leukemia L-1210. This compound is valuable in research applications focused on infection control and cancer biology. -
Bacterial Inhibitor
DS-8587 is a novel fluoroquinolone designed as a bacterial inhibitor, demonstrating significant antibacterial activity against amoxicillin-resistant Bacillus strains. Its minimum inhibitory concentration (MIC) values outperform those of ciprofloxacin and levofloxacin, while exhibiting reduced susceptibility to efflux pump-mediated resistance mechanisms such as adeA/adeB/adeC and abeM. Additionally, DS-8587 has a lower single-step mutation frequency compared to ciprofloxacin, positioning it as a promising therapeutic candidate for the treatment of amoxicillin-resistant Bacillus infections. -
Bacterial Inhibitor
Urechistachykinin I is a tachykinin-related peptide derived from echiuroid worms, primarily targeting bacterial pathogens. This compound exhibits significant antimicrobial activity while demonstrating no hemolytic effects, making it a valuable reagent for research into antimicrobial mechanisms and agents. Its unique properties make it suitable for studies investigating bacterial inhibition in various biological contexts. -
Antibacterial/Anti-inflammatory Agent
Antibacterial Agent 115 is a potent antibacterial and anti-inflammatory compound. It demonstrates significant efficacy in inhibiting bacterial growth while simultaneously modulating inflammatory responses. This compound is suitable for research applications aimed at understanding bacterial resistance mechanisms and the development of novel therapeutic strategies for bacterial infections and related inflammatory conditions. -
Anti-bacterial Agent
Antibacterial Agent 204 (Compd P2-56-3) is an anti-bacterial agent that exhibits enhanced Rifampin activity against Acinetobacter baumannii and Klebsiella pneumoniae. This compound disrupts the outer membrane of A. baumannii, which contributes to its antimicrobial efficacy. Antibacterial Agent 204 is applicable in research focused on developing novel treatments for infections caused by resistant bacterial strains. -
Antibacterial Agent
Antibacterial agent 82 (compound 7p) functions as an antibacterial agent targeting bacterial growth and proliferation. It exhibits significant efficacy against a range of Gram-positive and Gram-negative bacteria, making it suitable for studies focused on antimicrobial resistance and infection control. This compound is ideal for use in pharmacological research, including the development of new antibacterial therapies and mechanisms underlying bacterial pathogenesis. -
Antibacterial Compound
(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is an antibacterial compound known for its effectiveness against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting minimum inhibitory concentration (MIC) values of 4-32 μg/mL. Isolated from the roots of Atractylodes japonica, this compound serves as a valuable tool in the study of bacterial infections. Additionally, it functions as a click chemistry reagent due to its alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. -
Antifouling/Antibacterial Agent
Cochliomycin A is an antifouling and antibacterial agent derived from the Gorgonian-Derived Fungus Cochliobolus lunatus. It exhibits significant antifouling activity, with an EC50 of 1.2 μg/mL, effectively inhibiting barnacle larval settlement through stimulation of the NO/cGMP signaling pathway. Additionally, Cochliomycin A demonstrates moderate antibacterial efficacy against Staphylococcus aureus, making it valuable for research applications in marine biology and antimicrobial studies.

