Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Boromycin is an antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. Isolated from Streptomyces antibioticus, it exhibits potent activity against a range of gram-positive bacteria. This compound is valuable for research applications related to antimicrobial resistance and the development of new therapeutic agents. -
Peptide Antibiotic
Clavanin A is a peptide antibiotic that disrupts the integrity of the cytoplasmic membrane in target cells. It demonstrates effective bactericidal activity against Micrococcus flavus, making it a valuable tool for studying bacterial membrane dynamics and antibiotic mechanisms. Researchers can utilize Clavanin A for investigations into microbial resistance and the development of new antimicrobial strategies. -
Antibiotic
Altersolanol B, a fungal-derived compound, exhibits antibiotic properties through its ability to induce ATP catabolism in Ehrlich ascites tumor cells. This molecular action highlights its potential as a research tool for studying cellular energy dynamics and responses to antimicrobial agents. Altersolanol B may contribute to the understanding of antibiotic mechanisms and resistance patterns in cancer biology. -
Antibiotic
Ranbezolid is an orally active oxazolidinone antibiotic primarily targeting Gram-positive and Gram-negative anaerobes, including Staphylococcus aureus and Bacteroides fragilis. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, demonstrating an IC50 of 17 μM. Ranbezolid is effective in rapidly reducing bacterial load and has an enhanced cardiovascular safety profile. This compound is valuable for research applications focused on antibiotic effects against anaerobic bacteria. -
Sulfur-containing Antibiotic
Tropodithietic acid is a sulfur-containing antibiotic derived from the marine bacterium Phaeobacter inhibens. It demonstrates potent antibacterial activity against a wide range of bacterial species, including alpha- and gammaproteobacteria, flavobacteria, and actinobacteria. This compound is valuable for research applications involving antimicrobial resistance and the study of microbial interactions in marine environments. -
Antibiotic, Insecticide
Cafamycin is a polyether antibiotic that targets gram-positive bacteria, notably Staphylococcus aureus. In addition to its antibacterial properties, Cafamycin exhibits insecticidal and antiprotozoal activities. It is isolated from the culture fluid of Streptomyces sp., an organism recognized for producing various bioactive compounds, including the anthracycline antibiotic galtamycin. This compound is valuable for research applications in microbiology and pest control. -
Antibiotic
Avilamycin A is an orally active antibiotic that targets bacterial pathogens, particularly effective against veterinary strains of Clostridium perfringens (MICs ≤ 0.06-0.5 mg/L) and Brachyspira hyodysenteriae (MICs = 12.5-100 μg/ml). Its potent antibacterial properties make it a valuable reagent for research focused on combating bacterial infections in veterinary medicine. Avilamycin A is often utilized in studies aiming to understand antibiotic resistance mechanisms and to develop new therapeutic strategies against resistant bacterial strains. -
Antibiotic
(R)-10,11-Dehydrocurvularin is an antibiotic derived from the secondary metabolites of Curvularia species. It exhibits concentration-dependent cytotoxicity against various human tumor cell lines, with a mean IC50 value of 1.25 µM. This compound is valuable for research applications in cancer biology and the development of novel antimicrobial agents. -
Antibiotic
Erythromycin C is an antibiotic that primarily targets bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits potent activity against a wide range of gram-positive bacteria and some gram-negative pathogens. Erythromycin C is widely used in research to study bacterial resistance mechanisms and as a model compound in antibiotic development studies. Its properties make it a valuable tool in microbiological and pharmaceutical research. -
Antibiotic
Concanamycin A is a macrolide antibiotic that functions as an inhibitor of vacuolar type H+-ATPase (V-ATPase). By inhibiting V-ATPase, Concanamycin A disrupts lysosomal acidification, making it a valuable tool in the study of T cell-mediated inflammation. Its properties allow for exploration of cellular processes related to inflammation and lysosomal function, contributing to a better understanding of various disease mechanisms. -
Antibiotic
Streptomycin is an aminoglycoside antibiotic primarily targeting bacterial protein synthesis by binding to ribosomal RNA. It exhibits potent activity against Mycobacterium tuberculosis, making it essential for tuberculosis research. In addition, Streptomycin demonstrates bactericidal properties against various bacterial infections and interferes with nucleic acid interactions. Furthermore, this compound acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes, enabling its use in studies related to electrophysiological processes. -
Antibiotic
Istamycin Y0 is an aminoglycoside antibiotic with primary activity against bacterial ribosomes. Isolated from Streptomyces tenjimariensis ATCC 31603, it exhibits limited antibacterial efficacy against select bacterial strains. Istamycin Y0 is primarily used in microbiological research to study antibiotic resistance mechanisms and the pharmacodynamics of aminoglycosides. -
MRSA Antibiotic
MRSA Antibiotic 2 selectively targets methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. This compound demonstrates enhanced efficacy against Gram-positive bacteria while exhibiting minimal impact on Gram-negative bacteria and human cells. It is a valuable tool in the study of antibiotic resistance and the development of new therapeutic strategies for treating MRSA infections. -
Antibiotic
Sannamycin J is an aminoglycoside antibiotic that exhibits antimicrobial properties. Isolated from Streptomyces sannanensis sp. KC-7038, it demonstrates weak antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound serves as a valuable tool for research in antibiotic mechanisms and microbial resistance studies. -
Antibiotic
Trinactin is a macrotetrolide antibiotic that displays potent antibacterial activity through the disruption of bacterial cell membranes. Additionally, it functions as a cation carrier, facilitating ion transport across cellular membranes. This compound is significant for research applications focused on antibiotic development, cellular ion exchange mechanisms, and studying the effects of ionophore activity in various biological systems. -
Antibiotic
2'''-Hydroxychlorothricin is an antibiotic derived from the chlorothricin group, primarily targeting bacterial infections. Isolated from Streptomyces sp. K818, it exhibits anti-tumor properties and has been shown to extend the survival of ICR mice inoculated with Ehrlich cancer cells. This compound serves as a valuable tool in cancer research and microbiological studies focusing on antibiotic efficacy and tumor treatment. -
Antibiotic Intermediate
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics, targeting bacterial cell wall synthesis. It exhibits significant antibacterial activity and serves primarily in the synthesis of other antibiotics, such as Cefaclor and Cefprozil. This compound is valuable in microbiological research and the development of cephalosporin-based therapeutics. -
Antibiotic
Phenelfamycins C is an antibiotic derived from Streptomyces violaceoniger strains AB 9991-80 and AB 1047T-33. Its primary mechanism involves targeting and inhibiting the growth of eutrophic bacteria, demonstrating notable antibacterial activity. This compound is valuable for research applications focused on antibiotic development and studies of bacterial resistance mechanisms. -
Antibiotic
Sannamycin E is an aminoglycoside antibiotic derived from Streptomyces sannanensis KC-7038. It exhibits weak antibacterial activity primarily against Gram-positive bacteria. This compound is useful in research applications focused on antibiotic efficacy and resistance mechanisms. -
Antibiotic
2-Hydroxyaclacinomycin B is an anthracycline antibiotic known for its ability to inhibit RNA synthesis. Isolated from Streptomyces galilaeus A-862 (FERM BP-45), this compound exhibits significant anti-tumor activity. It serves as a valuable tool in cancer research, enabling studies focused on mechanisms of action and therapeutic potential within oncology. -
Antibiotic
Enopeptin A is a depsipeptide antibiotic primarily targeting Gram-positive and certain Gram-negative bacteria. Isolated from Streptomyces sp. RK-1051, it demonstrates potent activity against methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 25 μg/mL. Additionally, it exhibits efficacy against mutant strains of Escherichia coli and Pseudomonas aeruginosa, with MICs of 200 μg/mL. Enopeptin A is not effective against fungal pathogens, making it a valuable compound for studies focused on antibiotic resistance and bacterial infections. -
Antibiotic
Phenelfamycins D is an antibiotic derived from the actinobacteria Streptomyces violaceoniger AB 9991-80 and AB 1047T-33. It exhibits potent anti-eutrophic bacterial activity, making it a valuable tool for researching bacterial growth inhibition and antibiotic efficacy. Researchers can utilize Phenelfamycins D to explore its biological mechanisms and potential therapeutic applications in combating bacterial infections. -
Antibiotic
Saccharocarcin A is an antibiotic that targets a variety of bacterial and fungal pathogens. It has demonstrated activity against Mycobacterium luteus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans in disc diffusion assays. Additionally, Saccharocarcin A significantly inhibits Chlamydia trachomatis infection by 88% at a concentration of 0.5 μg/mL, while exhibiting low cytotoxicity in McCoy cells, making it a valuable reagent for studying infectious diseases and microbial resistance. -
Carbapenem Antibiotic
Tomopenem is a parenteral carbapenem antibiotic known for its extended half-life and broad-spectrum efficacy against various bacterial species. It exhibits potent antibacterial activity with a MIC90 ranging from 0.06 to 4 µg/mL across 293 clinical isolates, effectively targeting both aerobic and anaerobic organisms. Tomopenem is suitable for research applications focused on combating resistant bacterial infections and studying the mechanisms of action of carbapenem antibiotics. -
Antibiotic Agent
OES2-0017 is an antibiotic agent that targets spermine/spermidine acetyltransferase (SpeG) with an IC50 of 34.82 μM. This compound exhibits significant activity in inhibiting growth through low micromolar concentrations, demonstrating potent synergy with polyamines. At elevated concentrations, OES2-0017 disrupts bacterial membrane integrity, making it a valuable reagent for investigating bacterial growth inhibition mechanisms and polyamine metabolism in microbial research. -
Antibiotic
Respinomycin A1 is a natural antibiotic derived from Streptomyces sp. RK-483, exhibiting antimicrobial activity against various bacterial strains. This compound has been shown to induce differentiation in leukemic K-562 cells, highlighting its potential utility in cancer research and therapeutic development. Its unique mechanism of action makes Respinomycin A1 a valuable tool for investigating cellular differentiation and the pathways involved in leukemia. -
Antibiotic
Andrimid is a lipoacyl peptide that functions as an antibiotic through its action on bacterial cell envelope synthesis. It demonstrates significant antimicrobial activity, making it a valuable compound for researching antibiotic mechanisms and resistance. Additionally, Andrimid has potential applications in both biomedical research and agricultural biotechnology, particularly in developing strategies for disease control. -
Antibiotic Agent
Sulfadimethoxypyrimidine-d4 is a deuterium-labeled derivative of Sulfadimethoxypyrimidine, a sulfonamide antibiotic known for its broad-spectrum antibacterial activity. This compound acts by inhibiting bacterial dihydropteroate synthase, a key enzyme in folate biosynthesis, thereby disrupting DNA synthesis and bacterial growth. It is valuable for pharmacokinetic studies and metabolic research concerning sulfonamide antibiotics. -
Quinone Antibiotic
Granaticinic acid is a quinone antibiotic derived from Streptomyces thermoviolaceus NT1. It exhibits significant anti-gram-positive bacterial activity, making it a valuable compound for researching bacterial infections. Its unique mechanism of action provides insights into antibiotic resistance and the development of new therapeutic agents. -
Non-beta-lactam Antibiotic
Lactivicin is a non-beta-lactam antibiotic that exhibits beta-lactam-like activity by binding to penicillin-binding proteins (PBPs). It demonstrates moderate efficacy against a broad spectrum of Gram-negative bacteria and high effectiveness against Gram-positive bacteria. This compound is valuable for research in antibiotic resistance and the mechanisms of bacterial cell wall synthesis. -
Antibiotic
Griseolic acid C, an antibiotic compound, is identified as a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase (EC 3.1.4.17) with an IC50 of 0.12 μM, as demonstrated in studies utilizing rat brain extracts. Isolated from Streptomyces griseoaurantiacus SANK43894, Griseolic acid C exhibits significant biological activity that may be beneficial in various research applications related to cellular signaling and microbial resistance. -
Lipopeptide Antibiotic
Friulimicin D is a lipopeptide antibiotic derived from the actinomycete Actinoplanes friuliensis. It demonstrates significant antibacterial activity against a range of Gram-positive bacteria. Research applications include the study of bacterial resistance mechanisms and the potential development of novel antimicrobial therapies. -
Antitumor Antibiotic
Saintopin is an antitumor antibiotic that selectively inhibits DNA topoisomerases I and II, key enzymes involved in DNA replication and transcription. By inducing DNA cleavage, Saintopin disrupts the integrity of the genetic material, leading to apoptosis in cancer cells. This compound is utilized in research focused on cancer biology, particularly in studies involving mechanisms of chemotherapy resistance and DNA repair processes. -
Antibiotic
Cefonicid monosodium is a long-acting cephalosporin antibiotic that primarily targets bacterial cell wall synthesis. It possesses broad-spectrum antimicrobial activity, effectively combating a range of Gram-positive and Gram-negative bacteria. Additionally, Cefonicid acts as a noncompetitive inhibitor of class I β-lactamase, with a Ki value of 0.8 μM, making it a valuable reagent for research on bacterial infections and antibiotic resistance. -
Antibiotic
Neohydroxyaspergillic acid is an antibiotic that exhibits activity against specific bacteriophages. This compound can be utilized in research focusing on antibacterial mechanisms and the interaction between antibiotics and bacteriophages. Its potential applications extend to studying resistance and susceptibility patterns in microbial populations. -
Angucycline Antibiotic
Urdamycin A is an angucycline antibiotic derived from Streptomyces fradiae. Notably, it functions as an orange pH indicator, shifting to ultramarine blue at pH 7.7. Urdamycin A exhibits significant anticancer activity, showing IC50 values of 2.4 μg/mL in proliferation assays and 0.55 μg/mL in stem cell assays. This compound is relevant for research applications in cancer biology and antibiotic activity studies. -
Antibiotic
Fenbendazole is an orally active benzimidazole compound that primarily targets tubulin, acting as a microtubule destabilizing agent. It exhibits a broad antiparasitic activity by disrupting microtubule equilibrium in helminths. Additionally, fenbendazole is known for its anti-proliferative effects, inducing apoptosis and causing cell-cycle arrest in various cancer models. Its antitumor properties have been demonstrated in mice xenografted with wild-type p53, making it a valuable reagent for exploring mechanisms of cancer therapy. -
Antibiotic
Nalidixic acid is a quinolone antibiotic that primarily targets DNA gyrase and topoisomerase IV, interfering with bacterial DNA replication. It exhibits a bacteriostatic effect at lower concentrations and becomes bactericidal at higher concentrations. Nalidixic acid is effective against both gram-positive and gram-negative bacteria, making it valuable for studies involving bacterial infections and resistance mechanisms in microorganisms. -
Antibiotic
Secnidazole is an orally active azole antibiotic that primarily targets bacterial quorum sensing (QS) mechanisms. By inhibiting acylhomoserine lactones, Secnidazole attenuates the virulence of Pseudomonas aeruginosa and exhibits antimicrobial activity against a range of anaerobic Gram-negative and Gram-positive bacteria. This reagent is valuable for research applications related to diseases such as amoebiasis, giardiasis, and bacterial vaginitis, facilitating studies on their pathogenesis and treatment. -
Sulfonamide Antibiotic
Sulfadiazine is a sulfonamide antibiotic that inhibits bacterial folic acid synthesis by competitively antagonizing para-aminobenzoic acid (PABA). It exhibits antimalarial properties and is primarily utilized in research involving toxoplasmosis. Sulfadiazine's mechanism of action makes it a valuable tool for studying sulfamethoxazole efficacy and the interplay of antibiotics in parasitic infections. -
Antibiotic
Sulfameter, a sulfonamide antibiotic, exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Its long-acting formulation makes it suitable for research applications targeting bacterial infections, particularly in respiratory and urinary tracts. This compound serves as a valuable tool in the study of antibiotic efficacy and resistance mechanisms in various pathogens. -
Sulfathiazole Antibiotic
Sulfamethizole is a sulfathiazole antibiotic that inhibits the synthesis of folic acid and thymine, thereby affecting bacterial growth. It demonstrates antibacterial activity against Escherichia coli in urinary tract infections, though it is ineffective against sulII gene-positive strains. This compound is valuable for research into the mechanisms of urinary tract infections and the bioluminescence of Photobacterium phosphoreum. -
Sulfonamide Antibiotic
Sulfamethoxazole is a sulfonamide antibiotic that exerts its antibacterial effect by inhibiting bacterial folate metabolism. It achieves this by competitively interfering with 4-Aminobenzoic acid (PABA) at the active site of dihydropteroate synthetase and dihydropteroate reductase. This compound is primarily utilized in the research of urinary tract infections (UTIs), prostatitis, and bronchitis, making it a valuable tool for studying antibiotic resistance and bacterial infections. -
Antibiotic
Sulfanilamide is a potent sulfonamide antibiotic that primarily targets bacterial growth by inhibiting dihydropteroate synthase. This compound demonstrates significant biological activity against various pathogens, including inhibition of the lymphogranuloma venereum virus. Additionally, sulfanilamide acts as a carbonic anhydrase inhibitor, making it useful in a range of biochemical research applications, particularly in studies involving antibiotic resistance and enzyme dynamics. -
Antibacterial Antibiotic
Tebipenem pivoxil is an orally active antibacterial antibiotic that targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall synthesis. Its efficacy against a range of pathogenic bacteria makes it a valuable tool for research applications in microbiology and pharmacology, particularly in studying antibiotic resistance mechanisms and developing new therapeutic strategies. -
Cephalosporin Antibiotic
Cephalexin is a semisynthetic cephalosporin antibiotic known for its broad-spectrum activity against numerous gram-positive and gram-negative bacteria. It functions primarily by inhibiting penicillin-binding proteins (PBPs), which are essential for bacterial cell wall synthesis. This compound is widely utilized in research related to bacterial infections, including pneumonia, streptococcal throat infections, and bacterial endocarditis. Its oral bioavailability and efficacy make it a valuable tool in microbiological studies. -
Antibiotic
Amoxicillin is a beta-lactam antibiotic that targets bacterial cell wall synthesis. It exerts its antimicrobial activity by inhibiting the peptidoglycan biosynthesis necessary for cell wall formation, leading to impaired cell growth and division. Amoxicillin is widely used in various research applications to study bacterial infections and resistance mechanisms. -
Aminoglycoside Antibiotic
Amikacin hydrate is an aminoglycoside antibiotic that serves as a semisynthetic analog of kanamycin. It exhibits bactericidal activity by binding to the 30S and 50S ribosomal subunits in bacteria, ultimately inhibiting protein synthesis. This reagent is particularly effective against a wide range of Gram-negative bacteria, including strains resistant to gentamicin and tobramycin, as well as infections caused by susceptible Nocardia and nontuberculous mycobacteria. Amikacin hydrate is commonly utilized in research focused on combating antibiotic-resistant infections and studying mechanisms of antibiotic action. -
Antibiotic
Bacitracin Zinc is a complex of Bacitracin and zinc ions, functioning primarily as an antibiotic with bactericidal activity. This polypeptide antibiotic is effective in causing damage to bacterial DNA and deoxyribose, making it a valuable agent in combating microbial infections. Additionally, Bacitracin Zinc has been shown to enhance gut microbiota composition in broiler and beef cattle, contributing to improved overall health and growth performance in livestock research applications. -
Antibiotic
Carbenicillin disodium is a broad-spectrum semi-synthetic penicillin antibiotic targeting gram-negative bacteria. It exerts its antibacterial activity by inhibiting cell wall synthesis, making it effective in various microbiological applications. Due to its low toxicity, it is also suitable for use in plant tissue research.
