Antitubercular agent-57 is a selective antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against both drug-sensitive and multidrug-resistant strains, including extensively drug-resistant variants, while maintaining low toxicity towards mammalian cell lines, such as hepatocytes. Antitubercular agent-57 exhibits no cross-resistance with established first and second-line antitubercular agents and shows no antimicrobial activity against Gram-positive and Gram-negative bacteria or fungal strains. This reagent is valuable for research focused on tuberculosis and multidrug-resistant tuberculosis.
Antitubercular agent-57 is a selective antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against both drug-sensitive and multidrug-resistant strains, including extensively drug-resistant variants, while maintaining low toxicity towards mammalian cell lines, such as hepatocytes. Antitubercular agent-57 exhibits no cross-resistance with established first and second-line antitubercular agents and shows no antimicrobial activity against Gram-positive and Gram-negative bacteria or fungal strains. This reagent is valuable for research focused on tuberculosis and multidrug-resistant tuberculosis.
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