Linearmycin A is a polyene antibiotic targeting bacterial pathogens, derived from Streptomyces. It demonstrates significant antimicrobial activity against Staphylococcus aureus and Escherichia coli, with minimum inhibitory concentrations (MICs) of 3.1 and 1.6 μg/disc, respectively. Additionally, Linearmycin A exhibits antifungal properties, inhibiting Saccharomyces cerevisiae and Candida albicans with MICs of 0.1 and 1.6 μg/disc, respectively, and also shows effectiveness against the plant pathogenic fungus Aspergillus niger (MIC=0.2 μg/disc). This compound is valuable in research applications focused on bacterial and fungal infections, as well as the mechanisms of antibiotic action.
Linearmycin A is a polyene antibiotic targeting bacterial pathogens, derived from Streptomyces. It demonstrates significant antimicrobial activity against Staphylococcus aureus and Escherichia coli, with minimum inhibitory concentrations (MICs) of 3.1 and 1.6 μg/disc, respectively. Additionally, Linearmycin A exhibits antifungal properties, inhibiting Saccharomyces cerevisiae and Candida albicans with MICs of 0.1 and 1.6 μg/disc, respectively, and also shows effectiveness against the plant pathogenic fungus Aspergillus niger (MIC=0.2 μg/disc). This compound is valuable in research applications focused on bacterial and fungal infections, as well as the mechanisms of antibiotic action.
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