Antibacterial Agent 98 (Compound G37) is a potent orally active antibacterial compound that primarily targets Gyrase B by inhibiting its ATPase activity. This mechanism disrupts DNA supercoiling in Staphylococcus aureus, effectively exhibiting antibacterial activity. Notably, Antibacterial Agent 98 does not promote the development of resistance in methicillin-resistant S. aureus (MRSA), making it a valuable candidate for research in antimicrobial resistance.
Antibacterial Agent 98 (Compound G37) is a potent orally active antibacterial compound that primarily targets Gyrase B by inhibiting its ATPase activity. This mechanism disrupts DNA supercoiling in Staphylococcus aureus, effectively exhibiting antibacterial activity. Notably, Antibacterial Agent 98 does not promote the development of resistance in methicillin-resistant S. aureus (MRSA), making it a valuable candidate for research in antimicrobial resistance.
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