Antibacterial Agent 169 is a pyrrolamide-based inhibitor targeting GyrB and ParE, demonstrating significant antibacterial activity. It effectively inhibits Gyrase and Topo IV in Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L, respectively. This compound is valuable for research applications focused on combating bacterial infections and exploring mechanisms of antibiotic resistance.
Antibacterial Agent 169 is a pyrrolamide-based inhibitor targeting GyrB and ParE, demonstrating significant antibacterial activity. It effectively inhibits Gyrase and Topo IV in Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L, respectively. This compound is valuable for research applications focused on combating bacterial infections and exploring mechanisms of antibiotic resistance.
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