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Items 1101-1150 of 13505

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  1. KX-01-191 (compound 5c??) is a tin-precursor.
  2. N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a derivatives of pyrene (Py), and it is a alkyl maltopyranoside detergent, especially in transporters and respiratory complexes.
  3. SJA710-6 is a small molecule able to selectively differentiate MSCs toward hepatocyte-like cells.
  4. 2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2).
  5. KMO inhibitor

    GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50s of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO), respectively.
  6. RUVBL1/2 complex inhibitor

    CB-6644 is a selective inhibitor of RUVBL1/2 complex with anti-cancer activity. CB-6644 blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM.
  7. fucosylation inhibitor

    SGN-2FF is an oral inhibitor of fucosylation, directly inhibits fucosyltransferase activity, and possesses antitumor activity.
  8. RPH-2823 is a basic triamterene derivative, with diuretic activity.
  9. chymase inhibitor

    Fulacimstat is an orally available chymase inhibitor, with IC50s of 4, 3 nM for human and hamster chymase enzyme, respectively.
  10. Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats.
  11. 6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer.
  12. 17β-HSD3 inhibitor

    TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors.
  13. immunostimulant

    Sotirimod is an immunostimulant, and can potentially treat for actinic keratosis.
  14. cerebral vasodilator agent

    Viquidil (LM 192) is a cerebral vasodilator agent .
  15. paramagnetic contrast agent

    Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies. The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI.
  16. NCX1022 is an NO-releasing derivative of Hydrocortisone, which is the most widely used anti-inflammatory drug for the treatment of skin inflammation.
  17. apo inhibitor

    PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that could rescue impairments of mitochondrial motility and neurite outgrowth.
  18. anti-inflammatory

    Bucloxic acid is an anti-inflammatory pyrrazole derivative. Bucloxic acid can be used in the treatment of chronic glomerular nephropathies.
  19. Paliroden is an orally bioactive neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines, used for treatment of Alzheimer's Disease and Parkinson's.
  20. SAHA chloroalkane T1 is a chloroalkane capture tag by tethering Vorinostat (SAHA) and a chloroalkane tag T1.
  21. platelet aggregation inhibitor

    Ifenprodil glucuronide is a derivative of Ifenprodil. Ifenprodil is a vasodilator and an inhibitor of platelet aggregation, and Ifenprodil glucuronide has no effect on platelet aggregation and arterial contraction.
  22. protein-based AB5-type exotoxin

    Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough.
  23. GAGs biosynthesis

    Pro-xylane (Hydroxypropyl tetrahydropyrantriol) is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis.
  24. KLC2-SKIP Interaction inhibitor

    Kinesore is an inhibitor of the KLC2-SKIP Interaction.
  25. oral antidiabetic agent

    BM-131246 is an oral antidiabetic agent.
  26. Bencianol is a the semisynthetic flavinoid, with anti-spasmogenic activities.
  27. ST inhibitor

    Lith-O-Asp is a sialytransferase (ST) inhibitor, with IC50s of 12-37 μM.
  28. BRAG2 inhibitor

    Bragsin2 is a potent, selective and noncompetitive nucleotide exchange factor BRAG2 inhibitor, with an IC50 of 3 μM.
  29. ArfGEF BRAG2 inhibitor

    Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM.
  30. Oxyfenamate has anti-anxiety actions for use in anxiety neuroses.
  31. spastin inhibitor

    Spastazoline is a potent and selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC50 of 99 nM for Human spastin. Spastazoline shows no effect on ATPase activity of a recombinant human VPS4.
  32. MTHFD1/MTHFD2 inhibitor

    LY 345899 is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 0.018 μM.
  33. Padsevonil is a potent antiepileptic agent.
  34. Arrhythmias-Targeting Compound 1 is used in the research of arrhythmias, extracted from patent WO 2001028992 A2.
  35. IAA antagonist

    PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
  36. hepcidin production inhibitor

    DS28120313 (compound 32) is an orally hepcidin production inhibitor with an IC50 of 0.093 μM.
  37. Tegadifur is a fluorine-containing and anti-metabolic drug.
  38. rat adenylate kinase II inhibitor

    N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a Ka value of 22 ?M. N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor.
  39. aminocryptand ligand

    Octaaminocryptand 1 is an aminocryptand ligand.
  40. Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.
  41. Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
  42. Sulfo-NHS-Biotin is an amine-reactive biotinylation reagent.
  43. Sulfo-NHS-SS-Biotin is a water-soluble, NHS-ester biotinylation reagent.
  44. Biotin-HPDP is a sulfhydryl-reactive biotinylation agent.
  45. Iodoacetyl-LC-Biotin is a haloacetyl-activated sulfhydryl-reactive biotinylation reagent.
  46. Bisacodyl (INN) is a stimulant laxative drug that works directly on the colon to produce a bowel movement.
  47. LH-RH, human is a biochem/physiol Actions LHRH Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.
  48. Anisole methoxybenzene is a colorless liquid with a smell reminiscent of anise seed, and in fact many of its derivatives are found in natural and artificial fragrances.
  49. DBU
    DBU is a chemical compound and belongs to the class of amidine compounds.
  50. Triisopropylsilane is a highly selective reducing agent which can be used to prepare anti-1,2-diols.

Items 1101-1150 of 13505

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