Signaling Pathway
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| Discription | Spastazoline is a potent and selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC50 of 99 nM for Human spastin. Spastazoline shows no effect on ATPase activity of a recombinant human VPS4. |
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| Catalog Num | A19432 |
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| Formula | C20H30N8 |
| Molecular Weight | 382.51 |
| CAS Number | 2351882-11-4 |
| SMILES | CC(C)(C)C1=CC(NC2=NC(N3CCN[C@H](C(C)C)C3)=NC4=C2C=CN4)=NN1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 69 mg/mL (180.38 mM) | |
| Water | Insoluble | ||
| Ethanol | 18 mg/mL (47.05 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.14 mL | 130.72 mL | 261.43 mL |
| 0.5 mM | 5.23 mL | 26.14 mL | 52.29 mL |
| 1 mM | 2.61 mL | 13.07 mL | 26.14 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.23 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
