LY 345899

Catalog No.: A19440

MTHFD1/MTHFD2 inhibitor

LY 345899

LY 345899 Chemical Structure

CAS NO. 10538-99-5

LY 345899 is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 0.018 μM.

Availability: In stock

Package Price Qty
5 mg
$405.00
10 mg
$690.00
50 mg
$2,050.00
100 mg
$3,000.00
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Biological Activity

LY 345899 is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 0.018 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.06 mL 212.13 mL
0.5 mM 4.24 mL 21.21 mL 42.43 mL
1 mM 2.12 mL 10.61 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19440
Actions Inhibitor
M. Wt 471.42
Formula C20H21N7O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 10538-99-5
Synonyms LY345899; LY-345899
SMILES O=C(O)[[email protected]@H](NC(C1=CC=C(N2C(N3C4=C(NC(N)=NC4=O)NCC3C2)=O)C=C1)=O)CCC(O)=O

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