PP13

Catalog No.: A49799
Antimicrobial Peptide
PP13 is an antimicrobial peptide that exhibits activity against both Gram-negative and Gram-positive bacteria, demonstrating minimum inhibitory concentrations (MIC) of 16.7 µM against E. coli, 13.3 µM against B. subtilis, 23.3 µM against S. aureus, 8.0 µM against S. lutea, and 9.0 µM against B. pumilus. This potent peptide is useful in research applications focused on microbial resistance and the development of novel antimicrobial agents. Its broad-spectrum efficacy makes it a valuable tool for studying bacterial infections and designing therapeutic strategies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPP13 is an antimicrobial peptide that exhibits activity against both Gram-negative and Gram-positive bacteria, demonstrating minimum inhibitory concentrations (MIC) of 16.7 µM against E. coli, 13.3 µM against B. subtilis, 23.3 µM against S. aureus, 8.0 µM against S. lutea, and 9.0 µM against B. pumilus. This potent peptide is useful in research applications focused on microbial resistance and the development of novel antimicrobial agents. Its broad-spectrum efficacy makes it a valuable tool for studying bacterial infections and designing therapeutic strategies.
Product Information
Catalog NumA49799
FormulaC121H197N39O29
Molecular Weight2662.10
CAS Number1099486-04-0
SequenceGly-Ala-Ala-Arg-Lys-Ser-Ile-Arg-Leu-His-Arg-Leu-Tyr-Thr-Trp-Lys-Ala-Thr-Ile-Tyr-Thr-Arg
Sequence shorteningGAARKSIRLHRLYTWKATIYTR
SMILESC([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)[C@@H](C)O)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)C)=O)CCCCN)=O)NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)C)=O)C)=O)CCCNC(=N)N)=O)CCCCN)=O)CO)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)[C@@H](C)O)=O)C=4C=5C(NC4)=CC=CC5
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