Pol (476-484), HIV-1 RT Epitope

Catalog No.: A51716
Bioactive Peptide
Pol (476-484), HIV-1 RT Epitope is a bioactive peptide corresponding to residues 476-484 of the reverse transcriptase (RT) protein in HIV-1. This peptide acts as a dominant HLA A*0201-restricted epitope, playing a critical role in the immune response to HIV-1. It has been utilized in research to explore mechanisms underlying HIV-1 escape from cytotoxic T lymphocyte (CTL) recognition and is relevant for studying viral pathogenesis and developing vaccine strategies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPol (476-484), HIV-1 RT Epitope is a bioactive peptide corresponding to residues 476-484 of the reverse transcriptase (RT) protein in HIV-1. This peptide acts as a dominant HLA A*0201-restricted epitope, playing a critical role in the immune response to HIV-1. It has been utilized in research to explore mechanisms underlying HIV-1 escape from cytotoxic T lymphocyte (CTL) recognition and is relevant for studying viral pathogenesis and developing vaccine strategies.
Product Information
Catalog NumA51716
FormulaC46H78N12O12
Molecular Weight991.18
CAS Number139079-41-7
SequenceIle-Leu-Lys-Glu-Pro-Val-His-Gly-Val
Sequence shorteningILKEPVHGV
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(C)C)=O)CCCCN)=O)CCC(O)=O)(=O)N1[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(NCC(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)C(C)C)=O)CCC1
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