Catalog No.
Product Name
Application
Product Information
Citations
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HIV-1 Polypeptide
Cys-TAT(47-57) is a cell-penetrating peptide derived from the HIV-1 transactivating protein, specifically comprising the sequence Cys-[HIV-Tat (47-57)]. This arginine-rich peptide facilitates the delivery of therapeutic agents across cellular membranes. It is primarily utilized in research focused on HIV biology and the development of peptide-based drug delivery systems. -
Bioactive Peptide
DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a bioactive peptide that functions as a fluorogenic substrate for HIV-1 protease. This compound is crucial for advancing research in HIV pathology, as it enables continuous monitoring of protease activity through fluorescence resonance energy transfer (FRET) assays. Upon interaction with recombinant HIV-1 protease, cleavage occurs specifically at the Tyr-Pro bond, resulting in a notable increase in fluorescence that correlates with substrate hydrolysis. This substrate provides a reliable alternative to traditional HPLC or electrophoresis techniques for kinetic analysis of retroviral proteases, enhancing the study of HIV maturation and the development of targeted antiviral strategies. -
HIV-1 Gag Peptide Sequence
HIV-1 GAG peptide A-I is a specific peptide sequence derived from the HIV-1 Gag protein, functioning as a CD8+ T cell epitope. This reagent is instrumental in the study of immune responses to HIV-1 infection and plays a critical role in HIV vaccine research. Its application is essential for the evaluation of T cell responses in vaccine candidates and the characterization of immune recognition patterns. -
HIV-1 Polypeptide
MPG is a 27-amino acid peptide derived from the nuclear localization sequence of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. This peptide functions as an effective delivery agent for the transfection of nucleic acids and oligonucleotides into cultured cells. Its ability to facilitate cellular uptake of genetic material makes MPG a valuable tool for research applications in gene therapy and molecular biology. -
12-mer Peptide
Capsid assembly inhibitor is a 12-mer peptide that specifically targets the capsid (CA) domain of the Gag protein, effectively inhibiting the assembly of both immature and mature HIV-1 capsid particles in vitro. This compound serves as a valuable tool for studying HIV-1 replication mechanisms and evaluating potential antiviral strategies. Its ability to interfere with capsid formation makes it ideal for research in virology and the development of therapeutic agents against HIV-1. -
Antimicrobial Peptide
GLR-19 is an antimicrobial peptide with demonstrated anti-HIV properties. In addition to its efficacy against HIV, GLR-19 exhibits antiviral activity against herpes simplex virus type 2 (HSV-2). This compound is valuable for research applications focused on viral infections and the development of novel antiviral therapies. -
Epitope Peptide
HIV gag peptide (197-205) is an H-2Kd-restricted epitope derived from the p24 region of the HIV-1 gag protein, comprising the amino acid sequence AMQMLKETI. This peptide serves as a crucial tool for studying HIV-1 immune responses and T cell recognition. It is commonly utilized in vaccine development and immunological assays to analyze T cell activation and receptor specificity against HIV-1. -
Bioactive Peptide
Pol (476-484), HIV-1 RT Epitope is a bioactive peptide corresponding to residues 476-484 of the reverse transcriptase (RT) protein in HIV-1. This peptide acts as a dominant HLA A*0201-restricted epitope, playing a critical role in the immune response to HIV-1. It has been utilized in research to explore mechanisms underlying HIV-1 escape from cytotoxic T lymphocyte (CTL) recognition and is relevant for studying viral pathogenesis and developing vaccine strategies. -
Antimicrobial Peptide
Temporin C is an antimicrobial peptide that targets Legionella pneumophila. It exhibits significant antibacterial activity, making it a valuable tool for studying bacterial infections and developing new antimicrobial strategies. Its unique properties can aid in research focused on host-pathogen interactions and the development of novel therapeutic agents against bacterial pathogens. -
Antimicrobial Peptide
Temporin F is an antimicrobial peptide that exhibits activity against Legionella pneumophila, a pathogen responsible for severe pneumonia. This peptide targets bacterial membranes, disrupting their integrity and leading to cell death. Temporin F is valuable for research in antimicrobial resistance and the development of new therapeutic strategies against bacterial infections. -
Antimicrobial Peptide
Mastoparan B is an antimicrobial peptide derived from the venom of the hornet Vespa. This compound exhibits significant antimicrobial activity, disrupting cellular membranes and leading to cellular lysis. Mastoparan B's unique ability to alter the morphology of red blood cells from a standard disk shape to a serrated form makes it a valuable tool for studying membrane dynamics and cell morphology in various biological applications. It is particularly useful in research involving cell membrane interactions and antimicrobial efficacy. -
Antimicrobial Peptide
Peptide 5g is an antimicrobial peptide that exhibits potent activity against pathogenic microorganisms. It demonstrates inhibitory effects on Escherichia coli, Staphylococcus aureus, and Candida albicans, with minimal inhibitory concentration (MIC) values of 30, 10, and 12.5 μg/mL, respectively. This peptide can be utilized in research applications focused on the development of antimicrobial therapies and understanding the mechanisms of microbial resistance. -
HLA Class I-restricted CMV Peptide Epitope
VTEHDTLLY is an HLA class I-restricted peptide epitope derived from cytomegalovirus (CMV). It plays a crucial role in the activation and expansion of CMV-specific T cells, making it valuable for studying T cell responses in viral infections. This peptide can be utilized in both in vitro and in vivo research applications focused on immunology and vaccine development targeting CMV. -
CMV Peptide
CMV pp65 (415-429) is a synthetic peptide derived from the Cytomegalovirus (CMV) pp65 protein, serving as a control for cytomegalovirus-specific T cell responses. This peptide is utilized in various research applications including the assessment of cell-mediated immune responses and the study of CMV pathogenesis. Its specific features make it an essential tool for investigating CMV-related immune responses in both clinical and laboratory settings. -
CMV Epitope Peptides Fragment
CEF20 is a cytomegalovirus (CMV) pp65 epitope peptide fragment that is restricted by HLA-A*0201. This peptide, corresponding to amino acids 495-503, is useful for immunological studies focused on CMV-specific T cell responses. CEF20 can aid in the development of diagnostic assays and therapeutic strategies targeting CMV infections and is instrumental in research related to adaptive immunity. -
Antigen Peptide
IE1 peptide is an antigenic peptide derived from the immediate early (IE) gene of mouse cytomegalovirus (mCMV). It is critical for transcriptional activation during the mCMV replication cycle and serves as one of the earliest expressed viral genes. This peptide is a significant target for CD8+ T cell responses, making it valuable for research focused on host immune responses to mCMV infection. -
Anti-HIV Synthetic Peptides
T-22 is an anti-HIV synthetic peptide that specifically targets viral entry by disrupting the fusion process of the virus with host cells. Demonstrating potent antiviral activity with an EC50 of 0.008 μg/mL, T-22 exhibits a CC50 of 54 μg/mL, indicating its relative safety for cellular application. In addition to its antiviral properties, T-22 has been shown to enhance plant growth, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, as well as provide resistance against Cucumber Mosaic Virus (CMV). This multifunctional peptide serves as a valuable tool in both virology and agricultural research. -
Antimicrobial Peptides
Hs-1 is an antimicrobial peptide that exhibits significant antiviral activity, offering approximately 80% protection against the dengue-2 virus. This peptide is valuable for research into therapeutic agents targeting viral infections. Its mechanism involves perturbation of viral membrane integrity, making it a useful tool for studies on peptide-based antiviral strategies. -
Polypeptide
2A/2B Dengue protease substrate (Ac-RTSKKR-pNA) is a polypeptide substrate designed for the Dengue NS2B-NS3 protease. This substrate facilitates the understanding of protease activity by serving as a valuable tool in the development of selective inhibitors targeting the Dengue NS2B-NS3 protease. Its efficacy in research applications enhances the study of dengue virus pathogenesis and potential therapeutic strategies. -
EBV Peptide
EBNA3 246-254 (RYSIFFDYM) is an Epstein-Barr Virus (EBV) peptide that targets HLA-A24. This peptide is instrumental in the amplification of EBV-specific cytotoxic T lymphocytes (CTLs) through in vitro techniques, followed by HLA multimer staining. EBNA3 246-254 serves as a valuable tool for researching EBV-related pathologies, including lung cancer. -
Peptide Antigen
EBV EBNA3B (416-424) is an HLA-A11-restricted peptide antigen derived from the Epstein-Barr Virus (EBV) nuclear antigen 3B protein. This peptide is significant in studies related to EBV-associated malignancies and immune response. It is commonly utilized in research applications focusing on T-cell activation, antigen presentation, and vaccine development targeting EBV infections. -
Bioactive Peptide
BMLF1 (280–288) is a bioactive peptide derived from the Epstein-Barr Virus lytic protein, specifically targeting the HLA A2.1-restricted epitope. This peptide exhibits immunogenic properties and is utilized in research applications focused on antigen presentation and immune response studies. BMLF1 (280–288) serves as a valuable tool for investigating T cell activation and viral immunology. -
Immunogenic Peptide
IALYLQQNW is an immunogenic nonapeptide derived from the latent membrane protein 1 (LMP1) of the Epstein-Barr virus (EBV). As a latent T-cell epitope, IALYLQQNW effectively activates EBV-specific cytotoxic T lymphocytes (CTLs), facilitating the recognition and destruction of EBV-infected cells. This peptide is significant for investigating immune responses to EBV-associated malignancies, including Hodgkin's disease and nasopharyngeal carcinoma. It serves as a valuable tool for research into targeted immunotherapies and vaccine development against these cancers. -
Viral Antigen Peptide
EBNA-1 (386–405 aa) is a viral antigen peptide that exhibits cross-reactivity through its significant amino acid similarity to GlialCAM (370-389 aa). It induces the production of cross-reactive antibodies that target both Epstein-Barr virus (EBV) antigens and glial cells in the central nervous system, potentially initiating autoimmune responses. This peptide is valuable for research applications related to EBV infection and the pathophysiology of multiple sclerosis (MS). -
Single Peptide Epitope
CEF19 is a single peptide epitope derived from residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). This epitope plays a critical role in enhancing cytotoxic T-lymphocyte (CTL) recognition, making it a valuable tool for studying EBV-associated immune responses. CEF19 is applicable in research focused on viral pathogenesis, immune evasion, and vaccine development related to EBV infections. -
Bioactive Peptide
Epstein-Barr Virus BRLF1 (134-142) is a bioactive peptide that serves as a HLA-A11 restricted epitope derived from the BRLF1 protein of Epstein-Barr Virus. This peptide is valuable for research applications focusing on immune responses to viral infections, particularly in the context of Epstein-Barr Virus. It can aid in the development of vaccines and therapeutic strategies targeting EBV-related diseases. -
Antiviral Peptide
P9R is an antiviral peptide that exhibits broad-spectrum activity against multiple viruses, including coronaviruses (SARS-CoV-2, MERS-CoV, SARS-CoV), A(H1N1)pdm09, A(H7N9), and rhinovirus. Its primary mechanism involves direct binding to viral particles and inhibition of virus-host endosomal acidification, providing significant protection in murine models against A(H1N1)pdm09 infection without fostering drug resistance. P9R serves as a valuable research tool for studying pH-dependent respiratory viruses. -
Peptide
HBV Seq1 aa:141-151 is a peptide targeting the hepatitis B virus (HBV). This peptide is instrumental for research into the mechanisms of chronic HBV infection and immune response. It facilitates the study of viral epitope recognition and potential therapeutic interventions in HBV-related diseases. -
Cell-penetrating Peptide
Xentry is a cell-penetrating peptide (CPP) derived from the hepatitis B virus, featuring a sequence of seven amino acids (LCLRPVG). This peptide facilitates the efficient delivery of large biomolecules, such as antibodies, siRNAs, and enzymes, to various tissues in vivo, excluding circulating blood cells. Studies demonstrate that Xentry conjugated with anti-B-raf antibodies or siRNAs effectively induces cell death in B-raf-dependent melanoma cells, highlighting its potential in targeted cancer research and therapeutic applications. -
HBsAg Epitope Peptide
HBV Seq2 aa:208-216 is a HBsAg-derived CD8 epitope peptide targeting the immune response to Hepatitis B virus. This peptide plays a critical role in studying T cell recognition and can be utilized in vaccine development and immunological assays. Its application aids in understanding the host's immune response to HBV, contributing to research on therapeutic strategies against hepatitis B infection. -
PreS2 peptide
Hepatitis B Virus PreS Region (120-145) is a preS2 peptide that specifically inhibits the binding of single-chain variable fragment (scFv) or IgG to recombinant Hepatitis B surface antigen (r-HBsAg). This peptide serves as a valuable tool for studying Hepatitis B virus interactions and vaccine development, enabling researchers to explore therapeutic targets and improve diagnostic methods related to Hepatitis B infection. Its ability to disrupt binding makes it suitable for applications in immunology and virology research. -
HBsAg Peptide
HBV Seq2 aa:28-39 is a peptide derived from Hepatitis B Surface Antigen (HBsAg) that specifically interacts with major histocompatibility complex (MHC) class I molecules. This interaction is crucial for the activation of CD8+ T cells, making it an important tool for studying immune responses to HBV infection. It is widely used in vaccine research and T cell epitope mapping to enhance understanding of viral pathogenesis and immune evasion mechanisms. -
Depsipeptide
Destruxin B2 is a natural depsipeptide that primarily targets the secretion of hepatitis B surface antigen (HBsAg). It exhibits significant biological activity, with an IC50 value of 1.30 μM in inhibiting HBsAg secretion in Hep3B cells. This compound is valuable for research applications focusing on hepatitis B virus infection and potential therapeutic strategies. -
Peptide-Drug Conjugate
PhAc-ALGP-Dox is a peptide-drug conjugate designed for targeted anticancer therapy. This prodrug demonstrates significant cytotoxic activity against triple-negative breast cancer (TNBC) cell lines, with IC50 values ranging from 311 nM to 34.25 μM for E0771, MDA-MB-231, and MDA-MB-468, as well as exhibiting effects on colorectal carcinoma (CrC) cells (LS 174T) and normal epithelial cells. Its unique mechanism allows for selective delivery of doxorubicin, making it a valuable tool for research applications focused on improving chemotherapy efficacy and reducing off-target effects in cancer treatment. -
Peptide
BPP 5a is a bradykinin-potentiating peptide known for its vasorelaxant properties, derived from Bothrops jararaca venom. This peptide functions as an angiotensin-converting enzyme (ACE) inhibitor with a Ki value of 400 nM. BPP 5a is primarily utilized in research focused on hypertension and cardiovascular diseases, offering insights into potential therapeutic applications. -
Bioinspired Peptide
DDDEEKC is a bioinspired peptide that selectively adsorbs onto enamel surfaces, mimicking the function of statherin, a salivary protein. This peptide acts as a guiding agent for the remineralization of tooth enamel, significantly enhancing the regeneration of hydroxyapatite (HAP). DDDEEKC is valuable for research focused on in-situ repair of enamel demineralization, including conditions such as dental caries. -
Antitumor Peptide
Tezuvotide tetraxetan is an antitumor peptide designed to target cancer cells through specific receptor interactions. It exhibits potent antineoplastic activity, making it a valuable tool for studying tumor biology and therapeutic approaches in cancer research. Its mechanism of action and specificity provide insights into potential applications in targeted therapies and clinical investigations. -
Polypeptide
Ganipatide is a glucose-dependent insulinotropic polypeptide consisting of 31 amino acids. It plays a pivotal role in enhancing insulin secretion in response to food intake, making it significant in the study of glucose metabolism and diabetes management. This polypeptide is useful for investigating mechanisms of insulin regulation and potential therapeutic approaches for type 2 diabetes. -
Peptide for BH3 Profiling
MS1 peptide is a significant tool for BH3 profiling, designed to enhance the depolarization of mitochondrial membranes in melanoma cells, particularly those pre-treated with Encorafenib. This peptide serves as a valuable research reagent for investigating the mechanisms underlying BRAFV600E melanoma and its response to targeted therapies. Its application facilitates the exploration of apoptotic signaling pathways in cancer research, aiding in the development of novel therapeutic strategies. -
P53 Activating Peptide
PK7088 is a pyrazole-based compound that serves as a specific p53 activating peptide. It facilitates the reactivation of mutant p53, restoring its wild-type functionalities. Due to its ability to enhance p53 activity, PK7088 demonstrates significant anticancer properties, making it a valuable tool in cancer research aimed at targeting p53 mutations. -
Anticancer Peptide
PNC-27 is a chimeric anticancer peptide that targets HDM-2 through its p53-like structure. It induces selective membrane pore formation, leading to the lysis of cancer cells. This reagent is particularly applicable in research focused on acute myeloid leukemia and offers insights into mechanisms of apoptosis and tumor suppression. -
Bioactive Peptide
p53 CBS is a bioactive peptide that corresponds to the consensus binding sequence of the p53 tumor suppressor protein. This peptide is crucial for studying p53-DNA interactions and provides insights into the regulation of gene expression in response to cellular stress. Research applications include elucidating the mechanisms of p53-mediated transcriptional activation and investigating its role in tumorigenesis and apoptosis. -
Peptide
p53 (17-26) is a peptide derived from the MDM2 binding domain of the tumor suppressor p53, with a binding affinity (Kd) of 50 nM for MDM2. This peptide demonstrates significant biological activity by inducing necrosis in cancer cells through disruption of cellular integrity and nuclear membrane damage. Research applications for p53 (17-26) include studies focused on pancreatic cancer and the development of therapeutic strategies targeting MDM2-mediated pathways. -
Tumor Suppressor Peptide
p53 (232-240) is a peptide derived from the 232-240 amino acid sequence of the human tumor suppressor protein p53. This peptide enhances binding affinity to the Major Histocompatibility Complex (MHC), thus increasing its immunogenicity and bolstering the immune system's response to tumor antigens. p53 (232-240) is valuable in cancer vaccine development and studies focused on tumor cell recognition and clearance by immune cells. -
Inducing Peptide
Peptide 234CM is an inducing peptide that features isoleucine at position 3, reflecting a point mutation in p53 codon 234. This peptide is known to elicit strong cytotoxic T cell (CTL) responses and robust antitumor immune responses against the mutant form of p53. It is valuable in immunological research focusing on cancer therapy and the enhancement of immune response mechanisms. -
MDM2/p53 Inhibitor
Phage-derived 12/1 peptide is a potent inhibitor of the MDM2/p53 interaction, effectively disrupting the binding between MDM2 and p53, as well as MDMX and p53. This peptide demonstrates significant antitumor activity, exhibiting IC50 values of 0.15 μM for MDM2 and 1.25 μM for MDMX. It serves as a valuable tool for research investigating the modulation of p53 activity and the therapeutic potential in targeting MDM2/MDMX pathways in cancer. -
Polypeptide
N1-Glutathionyl-spermidine disulfide acts as a substrate for trypanothione reductase, an enzyme critical in the redox regulation of trypanothione in certain organisms. This compound plays a significant role in cellular antioxidant defense mechanisms and is relevant for studies involving oxidative stress and redox biology. Its use can enhance understanding of trypanosomatid parasites and the biochemical pathways they exploit, facilitating research in parasitology and drug development. -
Antiparasitic Agent
Cycloaspeptide A is an antiparasitic agent derived from the endophytic fungus Penicillium janczewskii. It exhibits potent biological activity against various parasitic organisms, making it a valuable tool in parasitology research. This compound holds promise for further exploration in the development of novel therapeutic strategies to combat parasitic infections. -
Tetrapeptide
AGPV is a tetrapeptide that demonstrates potential for the prevention of schistosome parasite infections. This compound may be valuable in research focused on developing novel therapeutic strategies for schistosomiasis, a significant public health concern. Its biological activity warrants exploration in parasitology and drug development applications. -
Chromogenic Peptide Substrate
Bz-Pro-Phe-Arg-pNA is a chromogenic peptide substrate designed for the detection and study of plasma and glandular kallikrein, cysteine proteinase (Cruzipain), and trypsin. This substrate facilitates real-time monitoring of enzyme activity through colorimetric changes, making it a valuable tool in biochemical assays. Additionally, Bz-Pro-Phe-Arg-pNA is applicable in Factor XII assays, enhancing research in coagulation and protease activity.
