Catalog No.
Product Name
Application
Product Information
Citations
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Antiplasmodial Peptide
Koshidacin B is an antiplasmodial cyclic tetrapeptide that exhibits potent activity against Plasmodium falciparum, with IC50 values of 0.89 μM for the FCR3 strain and 0.83 μM for the K1 strain. This compound effectively suppresses malaria parasites in vivo, making it a valuable tool for research in parasitic infections and the development of novel antimalarial therapies. -
Cyclodepsipeptide
Isariin D is a cyclodepsipeptide derived from the fungus Isaria felina, known for its potent insecticidal properties. This compound demonstrates significant biological activity against Galleria mellonella larvae, making it a valuable tool in entomological research and pest management studies. Its unique mechanism may provide insights into insect physiology and the development of natural insecticides. -
Cyclodepsipeptide
Isariin A is a cyclodepsipeptide derived from the fungus Isaria cretacea, known for its antimalarial properties. Research indicates its potential efficacy in inhibiting the proliferation of malaria parasites, making it a valuable compound for studies targeting malaria treatment and understanding related biological pathways. -
Cyclodepsipeptide
Isariin B is a cyclodepsipeptide derived from the fungus Isaria felina, recognized for its antimalarial properties. This compound demonstrates significant biological activity against Plasmodium species, making it a valuable tool in malaria research. Its unique structure and mechanism of action offer potential for the development of novel therapeutic agents in combating malaria. -
Retroviral Envelope Peptide
CKS-17 is a synthetic retroviral envelope peptide that targets the highly conserved amino acid sequences within the transmembrane envelope protein of various animal and human retroviruses. This peptide functions as an immunomodulatory epitope, exhibiting suppressive properties on numerous immune functions. CKS-17 is valuable for research applications focused on retroviral biology, immune modulation, and the development of therapeutic strategies against retroviral infections. -
Folate Receptor Alpha Peptide Ligand
FRα-targeting peptide C7 is a selective ligand that specifically binds to the folate receptor alpha (FRα). This peptide demonstrates targeted binding to FRα-expressing cells, facilitating in vivo tumor localization. It is a valuable tool for research applications in tumor diagnosis and therapeutic development, enabling targeted delivery of diagnostic and therapeutic agents. -
Chromogenic Peptide Substrate
Pyr-Pro-Arg-pNA hydrochloride is a chromogenic peptide substrate primarily targeting Factor XI and Activated Protein C (APC). It serves as a noncompetitive inhibitor of factor XI activation by binding to the active site of the factor XIa-light chain. This compound is essential for quantifying APC amidolytic activity in various biological assays, making it a valuable tool in coagulation research. -
Chromogenic Peptide Substrate
Pyr-Pro-Arg-pNA is a chromogenic peptide substrate specifically designed for Factor XI and Activated Protein C (APC). This reagent enables noncompetitive inhibition of Factor XI activation by binding to the active site of the factor XIa light chain. Pyr-Pro-Arg-pNA is primarily utilized for assessing APC amidolytic activity, making it a valuable tool in coagulation research and related studies. -
ATR Substrate
ATR kinase substrate peptide (ASELPASQPQPFSAKKK) functions as a specific substrate for ATR protein kinase, facilitating the detection of ATR kinase activity in biological research. This peptide is instrumental in studying cellular responses to DNA damage and the associated signaling pathways. It plays a critical role in validating ATR kinase activity and exploring its implications in cancer biology and therapeutic development. -
Cdk5 Peptide Inhibior
Cdk5i peptide is an inhibitor targeting cyclin-dependent kinase 5 (CDK5), displaying a strong binding affinity for the CDK5/p25 complex with a dissociation constant (Kd) of 0.17 μM. This peptide effectively disrupts the interaction between CDK5 and p25, subsequently reducing the kinase activity of the CDK5/p25 complex. Cdk5i peptide is particularly relevant for research into neurodegenerative diseases, providing a valuable tool for elucidating the role of CDK5 in neuronal function and pathology. -
Phosphopeptide
Histone H1-derived Peptide is a phosphopeptide designed to serve as a substrate for cyclin-dependent kinases (CDKs), specifically aligning with the optimal recognition motif for CDK1-cyclin B1. Its primary application lies in the detection of CDK1-cyclin B1 enzyme activity, making it an essential tool for studies focused on cell cycle regulation and protein phosphorylation dynamics. This peptide can facilitate research into the mechanisms governing cellular proliferation and the roles of CDKs in various biological processes. -
CDK2 Inhibitor
Cdk2/Cyclin Inhibitory Peptide I (Tat-LFG) is a specific inhibitor of cyclin-dependent kinase 2 (CDK2). It has demonstrated the ability to induce apoptosis in U2OS osteosarcoma cells in a dose-dependent manner, making it a valuable tool for studying CDK2-mediated cell cycle regulation. This peptide is suitable for research applications aimed at understanding the role of CDK2 in cancer biology and potential therapeutic interventions. -
Bioactive Peptide
Cdc2 kinase substrate is a bioactive peptide that serves as a specific substrate for cyclin-dependent protein kinase 1 (CDC2; CDK1). This substrate plays a crucial role in the regulation of the cell cycle by facilitating the phosphorylation activity associated with CDC2, enabling the transition from G2 to M phase. It is particularly useful in studies focused on cell cycle regulation, protein kinase signaling pathways, and the development of CDK inhibitors. -
CDK2 Inhibitor
Cdk2/Cyclin Inhibitory Peptide II is a specific inhibitor of cyclin-dependent kinase 2 (CDK2), primarily influencing cell cycle regulation. This peptide has demonstrated the ability to induce apoptosis in U2OS osteosarcoma cells in a dose-dependent manner. Its application in research includes investigations into cell cycle dynamics and therapeutic strategies for cancer treatment. -
Bioactive Peptide
SAP6 is a bioactive peptide that inhibits viral entry into host cells. This compound exhibits significant antiviral activity, making it a valuable tool for research in virology and infectious diseases. SAP6 can be utilized in studies aimed at understanding viral mechanisms and developing potential therapeutic strategies against viral infections. -
Immunodominant Peptides
NQK-Q8 peptide is an immunodominant peptide derived from the SARS-CoV-2 virus, specifically targeting T cell responses. It plays a crucial role in the evaluation of immune responses in COVID-19 research, making it a valuable tool for vaccine development and immunological studies. This peptide can assist in the identification and characterization of SARS-CoV-2-specific T cell responses in various experimental settings. -
Bioactive Peptide
HR2-18 is a bioactive peptide that targets the interaction between the SARS-CoV virus and host cell membranes. It demonstrates potent inhibition of viral penetration, thereby providing a valuable tool for studying viral entry mechanisms and developing antiviral strategies. This peptide is particularly relevant for research focused on coronavirus infections and therapeutic interventions. -
Arginine-enriched Peptide
BMV Gag-(7−25) is an arginine-enriched peptide known for its cell-penetrating capabilities. This peptide facilitates the delivery of therapeutic agents and genetic material, making it a valuable tool in drug delivery and gene therapy research. Its cellular uptake properties enhance the efficacy of treatments involving nucleic acids and other biomolecules. -
Peptide
Glu-Ala-Leu-Phe-Gln-pNA is a peptide substrate specific for Chiba virus 3C-like protease (CVP). This compound can be utilized to study proteolytic activity and enzyme kinetics related to CVP, providing insights into viral replication and pathogenesis. Its application in biochemical assays enables researchers to investigate therapeutic targets and potential inhibitors of the Chiba virus. -
Peptide-Paclitaxel Conjugate
ANG1005 is a peptide-paclitaxel conjugate designed to enhance brain delivery through targeted transport mechanisms. By covalently linking three paclitaxel molecules to Angiopep-2, ANG1005 effectively utilizes the low-density lipoprotein receptor-related protein (LRP1) pathway to cross the blood-brain and blood-cerebrospinal barriers. This innovative compound exhibits potent cytotoxicity against malignant cells, making it a valuable tool for research in brain tumor therapeutics and assessing drug delivery systems in neuro-oncology. -
Dipeptide
L-gamma-Glutamyl-L-threonine, a dipeptide, is formed through the condensation of the carboxyl group of L-glutamic acid and the amino group of L-threonine. This compound demonstrates antibacterial activity against Gram-negative bacteria and is linked to immune regulation. Additionally, L-gamma-Glutamyl-L-threonine serves as a flavor compound and can be utilized in research focused on inflammation and bacterial infections. -
HCV Core Protein
HCV Peptide (35-44) is a peptide derived from the HCV core protein, specifically spanning positions 35 to 44, serving as an HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope. This peptide is known to inhibit natural killer (NK) cell activity through two distinct mechanisms: direct interaction with KIR2DL2/3 and a synergistic effect via the CD94:NKG2A receptor. Its characterization is essential for research into HCV immunology and the development of therapeutic strategies targeting viral evasion of the immune response. -
Peptide
HCV Peptide (131-140) is a synthetic peptide derived from the hepatitis C virus (HCV) proteome. This peptide can be utilized in research focused on understanding HCV biology, immune response, and vaccine development. Its application extends to studies on viral protein interactions and the design of therapeutic strategies against hepatitis C infection. -
Tool Peptide
KK4A peptide is a tool peptide derived from the nonstructural protein 4A (NS4A) of the hepatitis C virus (HCV). It significantly enhances the catalytic efficiency of the NS3 protease, facilitating studies on HCV proteolytic mechanisms. This peptide serves as an invaluable resource for researchers investigating the function of NS3 protease and its role in HCV infection, contributing to the development of therapeutic strategies against hepatitis C. -
HCV NS4A Peptide
HCV NS4A Protein (18-40) (JT strain) is a peptide derived from the NS4A region of the hepatitis C virus, specifically comprising residues 18 to 40. This peptide enhances the catalytic efficiency of the NS3 protease, playing a crucial role in the viral lifecycle. It is valuable for research applications focused on understanding HCV replication mechanisms and developing antiviral therapies. -
Polypeptide
HCV-1 e2 Protein (484-499) is a polypeptide comprising 16 amino acids, derived from the envelope 2 (E2) protein of the hepatitis C virus. This peptide serves as a valuable tool for immunological studies, particularly in the analysis of antibody responses in individuals infected with HCV. Its applications extend to vaccine development and understanding virus-host interactions, facilitating advancements in hepatitis C research. -
Peptide
HCV Peptide (257-266) is a synthetic peptide derived from the hepatitis C virus (HCV) that targets immune responses associated with HCV infection. It is primarily utilized in research to study HCV-specific T-cell responses and to develop potential therapeutic strategies. This peptide is instrumental in understanding the pathogenesis of hepatitis C and may aid in vaccine development and immune modulation studies. -
HCV Peptide
HCV Core Protein (59-68) is a peptide derived from residues 59-68 of the Hepatitis C Virus (HCV) core protein. This peptide serves as an essential tool for studying HCV pathogenesis and immunological responses. It is commonly used in research applications such as vaccine development, peptide-based immunoassays, and understanding viral entry mechanisms. -
Synthetic Peptide
PQDVKFP is a synthetic peptide that targets antigenic domains of the hepatitis C virus (HCV) core protein. This peptide is valuable for the development of diagnostic assays and research focused on the immune response to HCV. Its specificity may facilitate studies into HCV pathogenesis and vaccine development. -
Antimicrobial Peptide
PP13 is an antimicrobial peptide that exhibits activity against both Gram-negative and Gram-positive bacteria, demonstrating minimum inhibitory concentrations (MIC) of 16.7 µM against E. coli, 13.3 µM against B. subtilis, 23.3 µM against S. aureus, 8.0 µM against S. lutea, and 9.0 µM against B. pumilus. This potent peptide is useful in research applications focused on microbial resistance and the development of novel antimicrobial agents. Its broad-spectrum efficacy makes it a valuable tool for studying bacterial infections and designing therapeutic strategies. -
Antibacterial Peptide
Latarcin 2a is a linear cationic antibacterial peptide derived from the venom of the spider Lachesana tarabaevi, exhibiting broad-spectrum antibacterial activity. It demonstrates a minimum inhibitory concentration (MIC) of 0.5 μM against both Bacillus subtilis and Escherichia coli. This peptide is primarily utilized in research related to infectious diseases and the development of novel antimicrobial agents. -
Peptide
Tetanus toxin (1301-1315) (C. tetani) is a C-terminal peptide fragment derived from the heavy chain of the tetanus toxin produced by Clostridium tetani. This peptide is instrumental in research related to pathogen-host interactions and immune responses. It serves as a valuable tool for studying tetanus infection mechanisms and potential therapeutic approaches in immunology. -
Antimicrobial Peptide
rCRAMP (rat) is a cathelin-related antimicrobial peptide that plays a crucial role in the innate immune response within the rat central nervous system. This peptide demonstrates significant antibacterial properties when extracted from rat brain tissues, highlighting its relevance in neuroimmunology research. Investigations into rCRAMP (rat) can provide insights into its potential therapeutic applications in combating infections and promoting brain health. -
Antimicrobial Peptide
Cyclopetide 2 is an antimicrobial peptide that exhibits moderate antibacterial activity against Bacillus subtilis, with a minimum inhibitory concentration (MIC) of 50 μg/mL. This compound is valuable for research applications focused on the development of antimicrobial agents and the study of peptide-based therapeutics. Its effectiveness in inhibiting bacterial growth makes it a relevant tool for exploring peptide interactions with microbial targets. -
Antimicrobial Peptide
Api137 is an antimicrobial peptide that targets bacterial ribosomes, inhibiting protein synthesis through the entrapment of release factors on the 70S ribosome after the hydrolysis of the nascent polypeptide chain. This mechanism effectively disrupts bacterial growth and viability. Api137 is utilized in research applications focused on understanding antibiotic resistance and exploring novel antimicrobial strategies. -
Antimicrobial Peptide
XT-2 peptide is an antimicrobial peptide derived from the skin secretions of Xenopus tropicalis. It exhibits significant antibacterial activity against Escherichia coli, with a minimum inhibitory concentration (MIC) of 8 μM. XT-2 peptide is useful in research applications focused on therapeutic interventions for bacterial infections and the study of host defense mechanisms. -
Antimicrobial Peptide
Apidaecin IA is an antimicrobial peptide that primarily targets bacterial membranes. This peptide exhibits significant antibacterial activity against a range of Gram-negative bacteria, making it a valuable candidate for research into novel antimicrobial therapies. Its unique mechanism of action and efficacy position it as a potential lead compound for the development of new antimicrobial agents in the fight against antibiotic-resistant infections. -
Antibacterial Peptide
CP7-FP13-2 is an antibacterial peptide that targets virulence factors in bacteria. It effectively inhibits the formation of biofilms in Staphylococcus aureus, demonstrating potent antibacterial activity in in vivo mouse models. This compound is valuable for research applications focusing on microbial resistance and the development of alternative therapeutic strategies against bacterial infections. -
Cyclic Dipeptide
Cyclo(Gly-His) is a cyclic dipeptide that exhibits antimicrobial and anticancer properties. It demonstrates significant cytotoxicity against HeLa and MCF-7 cells, with IC50 values of 1.699 mM and 0.358 mM, respectively. This compound is valuable for research in drug delivery systems and exploring its potential as a therapeutic agent. -
Antimicrobial Peptide
Maximin 4 is an antimicrobial peptide derived from the skin secretions of Bombina maxima. This peptide exhibits significant cytotoxic effects on tumor cells and demonstrates spermicidal activity. Its unique properties make it a valuable tool for research applications in cancer biology and reproductive health studies. -
Antimicrobial Peptide
Maximin 5 is an antimicrobial peptide derived from the skin secretions of Bombina maxima, exhibiting potent antimicrobial properties. This peptide demonstrates cytotoxic effects on tumor cells and a spermicidal effect, making it a valuable compound for research in cancer biology and reproductive health. Its unique mechanism of action provides a promising avenue for the development of novel therapeutic agents. -
Antimicrobial Peptide
Peptide 5e is an antimicrobial peptide that targets a range of pathogens. It demonstrates inhibition against E. coli, S. aureus, and C. albicans, with minimum inhibitory concentration (MIC) values of 30, 5, and 25 μg/mL, respectively. Peptide 5e may be utilized in research applications focused on antimicrobial resistance and the development of therapeutic agents against infections. -
Antimicrobial Peptide
Omiganan pentahydrochloride is a cationic antimicrobial peptide that exhibits a broad spectrum of antibacterial activity against both gram-positive and gram-negative bacteria, including yeast. Its primary mechanism involves disrupting bacterial cell membranes, leading to cell lysis and death. This reagent is particularly valuable for researching antimicrobial activity in the context of catheter-associated infections and evaluating efficacy against drug-resistant microbial strains. -
Antimicrobial Peptide
Temporin K is an antimicrobial peptide that targets Legionella pneumophila. This peptide exhibits potent antibacterial activity, making it a valuable tool for research in infectious disease and antimicrobial resistance. Its unique mechanism of action contributes to the overall understanding of host defense mechanisms and the development of new therapeutic agents. -
Antimicrobial Peptide
KAMP-19 is a keratin-derived antimicrobial peptide that exhibits potent activity against Pseudomonas aeruginosa. Its primary mechanism involves disrupting microbial cell membranes, ultimately leading to bacterial cell death. This peptide is a valuable tool for research focused on antimicrobial resistance and the development of new antimicrobial therapies. -
Cell-Penetrating Peptide
(RXR)4XB is a cell-penetrating peptide designed to enhance the delivery of phosphorodiamidate morpholino oligomers (PMOs) into bacterial cells. This peptide-conjugated PMO (PPMO) effectively disrupts biofilm formation and demonstrates potent antimicrobial activity against Pseudomonas aeruginosa, with an MIC50 ranging from 0.5 to 16 μM. Additionally, (RXR)4XB-PMO conjugates have shown significant efficacy in reducing bacterial burden in mouse models of acute pneumonia, making them valuable tools for studying bacterial infections and therapeutic interventions. -
Antimicrobial Peptide
Maximin 3 is an antimicrobial peptide derived from the skin secretions of Bombina maxima, targeting microbial pathogens through membrane disruption. It exhibits cytotoxic effects on tumor cells and demonstrates spermicidal activity, making it relevant for cancer and reproductive health research. Additionally, Maximin 3 shows significant anti-HIV activity, highlighting its potential in virology and infectious disease studies. -
Antimicrobial Peptide
Maximin 1 is an antimicrobial peptide that targets microbial cell membranes to exhibit potent antimicrobial activity. Isolated from the skin secretions of Bombina maxima, Maximin 1 demonstrates cytotoxic effects on tumor cells and spermicidal properties. This peptide serves as a valuable tool in research applications focused on antimicrobial resistance, cancer therapeutics, and reproductive biology studies. -
Antimicrobial Peptide
Cathepsin G(1-5) is an antimicrobial peptide derived from the clostripain-digested cathepsin G mixture. This peptide exhibits significant antimicrobial activity, making it valuable for research on host defense mechanisms and the development of novel therapeutic agents. Cathepsin G(1-5) is utilized in studies exploring its effects on bacterial pathogens and potential applications in infection control. -
Antibacterial Peptide
Albonoursin is an antibacterial peptide derived from microbial secondary metabolites, primarily targeting bacterial cell membranes. This compound exhibits significant antibacterial activity against a range of pathogenic organisms and shows potential for antitumor activity as well. Albonoursin is valuable in research focused on antibiotic development and cancer therapeutics.
