Connexin mimetic peptide 40GAP27

Catalog No.: A57387
Bioactive Peptide
Connexin mimetic peptide 40GAP27 is a bioactive peptide that targets the gap junction connexin 40 (Cx40). It is primarily utilized to study the effects of oxidative stress on gap junction intercellular communication. Research has demonstrated that 40GAP27 can attenuate endothelium-dependent subintimal smooth muscle hyperpolarization, providing insights into vascular function and pathology. This peptide is a valuable tool for investigations into cardiovascular health and the role of gap junctions in cellular signaling.
Grouped product items
Size Price Stock Qty
5mg
$55.00
In stock
10mg
$90.00
In stock
25mg
$185.00
In stock
50mg
$285.00
In stock
100mg
$450.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionConnexin mimetic peptide 40GAP27 is a bioactive peptide that targets the gap junction connexin 40 (Cx40). It is primarily utilized to study the effects of oxidative stress on gap junction intercellular communication. Research has demonstrated that 40GAP27 can attenuate endothelium-dependent subintimal smooth muscle hyperpolarization, providing insights into vascular function and pathology. This peptide is a valuable tool for investigations into cardiovascular health and the role of gap junctions in cellular signaling.
Product Information
Catalog NumA57387
FormulaC58H96N16O17
Molecular Weight1289.48
CAS Number403858-30-0
SequenceSer-Arg-Pro-Thr-Glu-Lys-Asn-Val-Phe-Ile-Val
Sequence shorteningSRPTEKNVFIV
SMILESC([C@@H](NC([C@H](CO)N)=O)CCCNC(=N)N)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)[C@H](CC)C)=O)=O)C(C)C)=O)CC(N)=O)=O)CCCCN)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC1
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