Catalog No.
Product Name
Application
Product Information
Citations
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Antimicrobial Peptide
Meliponamycin A is an antimicrobial cyclodepsipeptide targeting bacterial membranes. It exhibits potent antimicrobial activity against a range of pathogenic bacteria, making it a valuable tool for research in antibiotic drug development and microbial resistance studies. Its unique mechanism of action involves disrupting membrane integrity, which further elucidates its potential in combating bacterial infections. -
Antimicrobial Peptide
Gageotetrin C is an antimicrobial peptide derived from the marine bacterium Bacillus subtilis, primarily targeting fungal pathogens. It demonstrates potent antifungal activity, with a minimum inhibitory concentration (MIC) in the range of 0.02-0.04 μM. This compound is suitable for research applications focused on developing antifungal therapies and studying the mechanisms of antimicrobial peptides. -
Dipeptide
Isoleucylcysteine is a dipeptide composed of isoleucine and cysteine, serving as an intermediate in bacitracin biosynthesis. This compound may be employed in studies focused on peptide synthesis and the metabolic pathways involved in antibiotic production. Its role in bacitracin synthesis makes it valuable for research into antibiotic mechanisms and the regulation of peptide formation in microbial systems. -
Antibacterial Agent
LMW peptide is an antimicrobial peptide that targets a broad spectrum of bacterial strains. It exhibits significant antibacterial activity against both Gram-positive bacteria, such as Bacillus subtilis and Listeria monocytogenes, as well as Gram-negative bacteria, including Escherichia coli, Pseudomonas aeruginosa, and Vibrio cholerae. This makes LMW peptide a valuable reagent for research applications aimed at investigating antimicrobial mechanisms and developing new antibacterial therapies. -
Antimicrobial Peptide
K4 peptide is an antimicrobial peptide that exhibits potent activity against both Gram-positive and Gram-negative bacteria, including clinically relevant pathogens such as Staphylococcus aureus and various Marine Vibrio species. This compound is valuable in research focused on antibiotic resistance and the development of novel antimicrobial agents. Its broad-spectrum efficacy makes it a significant tool for studying microbial interactions and properties within infectious diseases. -
Antimicrobial Peptide
Maximin 2 is an antimicrobial peptide derived from the skin secretions of Bombina maxima. It exhibits significant cytotoxicity against tumor cells and demonstrates spermicidal activity. This peptide serves as a valuable tool in cancer research and reproductive health studies, facilitating investigations into novel therapeutic strategies and antimicrobial mechanisms. -
Antimicrobial Peptide
Bovine neutrophil beta-defensin 12 is an antimicrobial peptide that exhibits potent antibacterial activity against Escherichia coli and Staphylococcus aureus. This peptide plays a crucial role in the innate immune response by neutralizing pathogens and promoting microbial homeostasis. Its unique mechanism of action makes it valuable for research applications focused on antimicrobial resistance and the development of new therapeutic strategies. -
Antimicrobial Peptide
Temporin G is an antimicrobial peptide that exhibits activity against Legionella pneumophila. This compound demonstrates potent antimicrobial properties, making it valuable for research applications focused on infectious diseases and the development of novel antimicrobial therapies. Its ability to disrupt bacterial membranes positions Temporin G as a promising candidate for further investigation in combating antibiotic-resistant pathogens. -
Antibacterial Peptide
Plantaricin F is an antibacterial peptide that demonstrates potent inhibitory activity against various gram-negative bacteria, including the foodborne pathogens Salmonella enteritidis and Pseudomonas aeruginosa. Additionally, Plantaricin F effectively targets several species of Lactobacillus, Pediococcus, and Leuconostoc. This reagent is suitable for research applications focused on antibiotic development and the study of antimicrobial peptides. -
Antimicrobial Peptide
Catestatin (mouse) is an antimicrobial peptide that primarily targets Mrgprb2, displaying robust activation with an EC50 of 59.73 μM. This peptide is highly effective in facilitating the clearance of methicillin-resistant Staphylococcus aureus (MRSA) from wound infections. Additionally, Catestatin (mouse) plays a significant role in modulating the inflammatory immune response associated with MRSA infection, making it a valuable reagent for research in antimicrobial therapies and immune response studies. -
Antimicrobial Peptide
Brevinin-2EC is an antimicrobial peptide derived from the skin secretions of the amphibian Rana esculenta. It exhibits potent antimicrobial activity against a wide range of bacteria, fungi, and viruses, making it a valuable tool for research in infectious disease and antibiotic resistance. This peptide may also serve as a model for the development of novel antimicrobial agents and therapeutic strategies. -
Dipeptide
Beta-alanyl-L-lysine is a dipeptide consisting of L-lysine and beta-alanine. This compound exhibits notable antistaphylococcal and antifibrinolytic activities, making it a valuable reagent in microbiological and biochemical research. Its endogenous presence in organisms, such as Tibetan sheep, suggests potential physiological relevance and warrants further investigation into its biological functions and therapeutic applications. -
Antimicrobial Peptide
Cecropin D is an antimicrobial peptide that exhibits a minimum inhibitory concentration (MIC) of 4.55 μg/mL. It demonstrates efficacy against both Gram-negative and Gram-positive bacterial strains. In addition to its antibacterial properties, Cecropin D possesses antiviral, antifungal, antitumor, and immunomodulatory activities, making it a valuable tool for diverse research applications in microbiology and therapeutic development. -
Antibacterial Peptide
Zaloganan is an antibacterial peptide that functions by disrupting bacterial membranes. This compound displays broad-spectrum antibacterial activity against various pathogens, making it useful in research related to antimicrobial resistance and infection control. Its ability to compromise membrane integrity can provide insights into peptide-mediated mechanisms of action and the development of novel therapeutic agents. -
Chimeric Antimicrobial Peptide
cCBD-LL37 is a chimeric antimicrobial peptide featuring a collagen-binding domain (cCBD), enhancing its retention on collagen matrices. This peptide exhibits potent antimicrobial activity and maintains structural stability across a range of ionic strengths and pH levels (5.5-8). Its binding to collagen involves a combination of specific and non-specific interactions, initiated by long-range electrostatic forces. cCBD-LL37 is primarily utilized in research involving collagen-based biomaterials, such as wound dressings, where enhanced bacterial resistance and retention are critical. -
Antimicrobial Peptide
OP-145 is a derivative of the antimicrobial peptide cathelicidin LL-37, specifically targeting bacterial pathogens. It exhibits significant antibacterial activity against various strains of MRSA, making it a valuable tool for research in the area of chronic suppurative otitis media. OP-145 can be utilized to explore mechanisms of antimicrobial resistance and potential therapeutic applications in treating resistant infections. -
Antimicrobial Peptide
EcAMP3 is an antimicrobial peptide that exhibits significant antifungal and antibacterial properties. Its unique hairpin-like structure is characterized by a precursor family containing seven identical cysteine motifs, specifically C1XXXC2(11–13)C3XXXC4. This compound is valuable for research applications in understanding innate immunity and developing novel therapeutic agents targeting microbial infections. -
Antimicrobial Peptide
Combi-1 is an antimicrobial peptide that demonstrates broad-spectrum activity against various bacterial and yeast strains. It functions by disrupting microbial cell membranes, leading to cell lysis and death. This peptide is ideal for research applications focused on understanding the mechanisms of antimicrobial resistance and developing new therapeutic strategies against infectious agents. -
Antimicrobial Peptide
RP-1 is an antimicrobial peptide that exhibits activity against various pathogens, including Staphylococcus aureus, Salmonella typhimurium, Escherichia coli, and Candida albicans. It functions by disrupting microbial membranes, leading to cellular lysis and death. This peptide is utilized in research applications aimed at understanding antimicrobial resistance and developing new therapeutic strategies for infectious diseases. -
Antimicrobial Peptide
Polyphemusin II is an antimicrobial peptide derived from the hemocytes of Limulus polyphemus. It demonstrates potent antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria, as well as fungal species. This compound is valuable for research applications focusing on antimicrobial mechanisms and the development of new therapeutics targeting infectious agents. -
Cyclic Peptide
Desferriferribactin is a cyclic peptide characterized by its thirteen-membered ring structure. As a precursor to pyoverdins, it plays a crucial role in the iron acquisition process of certain bacteria. This compound is of interest in studies focusing on microbial physiology and the mechanisms of iron transport and regulation in pathogenic organisms. -
Antimicrobial Peptide
Maximin H5 is an antimicrobial peptide derived from the skin of the toad Bombina maxima. This peptide exhibits potent antibacterial and antifungal activity, making it a valuable tool for research in antimicrobial therapies. Its mechanism of action involves disrupting microbial cell membranes, which can be leveraged in studies related to infection control and the development of new antimicrobial agents. -
Antimicrobial Peptide
CaLL is an antimicrobial peptide that exhibits potent antibacterial activity against Bacillus anthracis, including both vegetative and spore forms, as well as Burkholderia cepacia. The minimum inhibitory concentrations (MIC) for these organisms are 7.8 μg/mL for B. anthracis and 31.3 μg/mL for both B. anthracis (vegetative) and B. cepacia. This peptide is valuable for research applications focusing on antimicrobial resistance and the development of peptide-based therapeutics. -
Antimicrobial Peptide
Decoralin is a cationic alpha-helical antimicrobial peptide that targets bacterial membranes, leading to their disruption and cell death. Isolated from the venom of Oreumenes decorates wasps, Decoralin demonstrates selective and rapid antimicrobial activity against various bacterial strains. This peptide serves as a valuable tool for antimicrobial research and the development of new therapeutic strategies. -
Bacterial Inhibitor
Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide derived from Bombina species, primarily functioning as a bacterial inhibitor. This peptide exhibits potent activity against a range of bacterial strains, making it a valuable tool for research in antimicrobial resistance and the development of new therapeutic agents. Its unique mechanism and efficacy position it as an important candidate for studies focused on infection control and peptide-based drug design. -
Antimicrobial Peptide
Brevinin-1Ea is an antimicrobial peptide derived from the skin secretions of the European green frog, Rana esculenta. This peptide exhibits broad-spectrum antimicrobial activity against various bacteria and fungi, making it a valuable tool in studies related to innate immunity and host defense mechanisms. Its unique properties allow researchers to explore potential applications in developing novel antimicrobial agents and enhancing skin protection strategies. -
Antimicrobial Peptide
Heliomicin is an antimicrobial peptide derived from Heliothis virescens, exhibiting potent antimicrobial activity against a range of bacterial and fungal pathogens. This peptide disrupts microbial membranes, leading to cell lysis and death. Heliomicin is valuable for research applications in antimicrobial drug development and studying the mechanisms of peptide-mediated membrane disruption. -
Antimicrobial Peptide
XT-1 is an antimicrobial peptide derived from the skin secretions of Xenopus tropicalis. It exhibits potent activity against Staphylococcus aureus, Escherichia coli, and Candida albicans, with minimum inhibitory concentrations (MIC) of 5 μM, 6 μM, and 50 μM, respectively. XT-1 is valuable for research applications focusing on antimicrobial resistance and the development of novel therapeutic agents targeting pathogenic microorganisms. -
Antimicrobial Peptide
eCATH-1 is an antimicrobial peptide derived from equine sources, exhibiting potent activity against both Gram-positive and Gram-negative bacteria. This peptide demonstrates a broad spectrum of antimicrobial effects, making it a valuable tool for research applications in infectious disease and antibacterial drug development. Its mechanism of action involves disrupting bacterial cell membranes, thereby contributing to its effectiveness in eradicating a variety of bacterial pathogens. -
GarKS Peptide
Garvicin KS, GakB is a 34-amino acid peptide that forms part of the bacteriocin garvicin KS (GarKS) alongside GakA and GakC. This peptide demonstrates significant inhibitory effects on fibroblast viability and proliferation, making it valuable for investigations into cell growth regulation. In addition, Garvicin KS, GakB shows potent antimicrobial activity against methicillin-sensitive Staphylococcus aureus (MSSA), with minimum inhibitory concentration (MIC) values indicating a stronger efficacy compared to GakA and GakC. This makes it a key tool for research in antimicrobial applications and cell proliferation studies. -
Antimicrobial Peptide
Apidaecin IB is an insect-derived antimicrobial peptide that exhibits significant antibacterial activity. It demonstrates minimum inhibitory concentration (MIC) values of 8 μM against various strains of Escherichia coli, including ML35, O18K1H7, and ATCC 25922. This peptide is valuable for research applications focusing on antimicrobial resistance and the development of new therapeutic agents. -
N-acetyl Phosphinothricin Tripeptide
N-Acetylbialaphos is an N-acetyl phosphinothricin tripeptide that targets the glutamine synthetase enzyme. This compound exhibits potent herbicidal activity, inhibiting nitrogen metabolism in plants. It is widely used in research applications related to agricultural biotechnology, particularly in the development of herbicide-resistant crops and the study of herbicidal mechanisms. -
Folate-Peptide Moiety
EC119 is a folate-peptide conjugate consisting of Pteroic acid fused with gGlu-Asp-Arg-Asp-Asp-Cys. This compound facilitates targeted delivery in cellular systems due to its affinity for folate receptors. EC119 is utilized in research applications aimed at enhancing the efficacy of drug transport and improving therapeutic outcomes in folate-receptor-overexpressing cancers. -
Microtubule-Stabilizing Peptide
Davunetide is a microtubule-stabilizing peptide derived from the activity-dependent neuroprotective protein (ADNP). It exhibits neuroprotective and neurotrophic properties, enhancing cognitive function. Davunetide selectively interacts with and stabilizes neuron-specific βIII-tubulin in vitro, facilitating structural integrity within neurons. Additionally, it penetrates the blood-brain barrier and demonstrates non-toxic characteristics while effectively inhibiting amyloid beta (Aβ) aggregation and the resultant neurotoxicity, making it valuable for research in neurodegenerative diseases. -
Angiogenesis Peptide Inhibitor
ALM-201 is a peptide antagonist of angiogenesis that specifically targets microtubules. It demonstrates significant biological activity by inhibiting cell migration, tubule formation, and microvessel development. ALM-201 is suitable for research applications focused on cancer biology and the mechanisms underlying tumor vascularization. -
KRT1 Receptor-targeting Peptide
Breast cancer targeting peptide 18–4 is a KRT1 receptor-targeting peptide characterized by a binding affinity (Kd) of 0.98 μM. This peptide, with the amino acid sequence WxEAAYQrFL, serves as an analogue of the P160 peptide. When covalently conjugated with the anticancer peptide MccJ25, it significantly enhances the cellular uptake of MccJ25 in breast cancer cells, thereby improving its anticancer efficacy. The resulting conjugate demonstrates IC50 values of 14.2, 20, and 25 μM against MCF-7, MDA-MB-435, and MDA-MB-435-MDR cell lines, respectively, making it valuable for research in breast cancer therapy. -
Breast Cancer Targeting Peptide
P160 peptide is a breast cancer-targeting peptide that specifically binds to the keratin 1 (KRT1) receptor on breast cancer cells, exhibiting a dissociation constant (Kd) of approximately 1.1 μM. This peptide markedly enhances the cellular uptake and pro-apoptotic activity of the antimicrobial peptide MccJ25 (microcin J25). P160 peptide serves as a valuable tool in cancer research, facilitating targeted drug delivery and improving therapeutic efficacy in breast cancer models. -
Octamer Peptide
OVA Peptide (257-264) is an octameric peptide epitope derived from ovalbumin that is specifically presented by the class I major histocompatibility complex (MHC) molecule H-2Kb. This peptide is crucial for T cell recognition and activation in immunological studies. It has applications in the development of immunotherapies, vaccine research, and studies focusing on T cell responses. -
Bioactive Peptide
OVA-Q4 Peptide is a bioactive peptide that serves as a variant of the ovalbumin-derived agonist peptide (SIINFEKL). It is recognized as a class I (Kb)-restricted peptide epitope presented by the H-2Kb major histocompatibility complex in mice. This peptide is instrumental in immunological research, particularly in studies involving T cell activation and antigen presentation. OVA-Q4 is valuable for applications in vaccine development and cellular immune response assessment. -
Antigen Peptide
OVA(250-264) is an antigenic peptide derived from ovalbumin, targeting the class I MHC molecule H-2Kb. This peptide has been shown to significantly enhance the generation and infiltration of antigen-specific CD8+ T cells when used in conjunction with αMSLN (anti-MSLN antibody), thus improving antitumor efficacy in orthotopic models of pancreatic cancer. OVA(250-264) serves as a valuable tool for the development of neoantigen vaccines in immunotherapy research focused on pancreatic cancer. -
HLA-DR Binding Epitope
PADRE peptide is a pan-HLA-DR binding epitope that functions as an immunostimulant by binding to the peptide-binding groove of MHC class II molecules, facilitating the activation of CD4+ T cells. This leads to enhanced anti-tumor immune responses, inhibition of tumor growth, and prolonged survival in model systems. PADRE peptide is effective in increasing the frequency of E7-specific CD8+ T cells and improving therapeutic outcomes when combined with E7 peptide-based vaccines and poly (I:C). It is suitable for research applications in various tumor models, including melanoma, glioblastoma, and cervical cancer. -
Bioactive Peptide
CMV pp65(13-27) is a bioactive peptide derived from amino acid residues 13 to 27 of the 65 kDa lower matrix phosphoprotein of human cytomegalovirus. This peptide encompasses a nine-amino-acid sequence (LGPISGHVL) that aligns with the consensus binding motif of the major histocompatibility complex H2-Dd T-cell epitope. It is utilized in immunological research, particularly for the study of T-cell responses and the development of cytomegalovirus vaccines. -
Peptide
MOG (89-113), human is a peptide derived from the myelin oligodendrocyte glycoprotein, which plays a critical role in myelin sheath formation and stability. This peptide fragment is utilized in research applications related to demyelinating diseases, including multiple sclerosis, where it serves as a target for studying immune responses and T cell activation. Its role in the modulation of inflammation makes it a valuable tool for understanding neuroinflammatory processes. -
WT1 Peptide
WT1 126-134 peptide is a peptide derived from the Wilms' tumor oncogene protein (RMFPNAPYL) that targets HLA-A0201. This peptide is known to induce cytotoxic CD8 T cells, which are capable of identifying and eliminating WT1-positive tumor cells. Additionally, WT1 126-134 peptide forms highly stable complexes with H-2Db (mouse) or HLA-A0201 (human), demonstrating a strong affinity (Kd = 0.2 nM) for humanized monoclonal antibodies (IgG1). It is applicable in immunotherapy as a vaccine for T cell activation or as a target for antibody development. -
Nucleoprotein Peptide
H2-D b restricted epitopes VSV Nucleoprotein (52-59) is a 9-mer peptide specifically derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). This peptide interacts with MHC class I molecules, facilitating the presentation to CD8+ T cells and promoting the activation of cytotoxic T lymphocytes (CTLs). It is particularly valuable in research focused on CTL vaccine development for infectious diseases, including Ebola virus, enhancing understanding of immune responses in viral infections. -
Polypeptide
MBP (111-129) is a polypeptide that represents an immunodominant epitope cluster restricted by HLA-DRB1*0401. This compound functions as an antagonist for the HD4-1C2 T cell receptor and as an agonist for the MS2-3C8 T cell receptor. MBP (111-129) is valuable for research in multiple sclerosis and T cell biology, providing insights into immune responses and potential therapeutic interventions. -
HLA-B7-Derived Peptide
Allotrap 07 is a synthetic peptide derived from residues 75-84 of the HLA-B7 molecule, a class I major histocompatibility complex (MHC) protein. This peptide is known for its ability to promote donor-specific tolerance in rat cardiac allografts when used in conjunction with Cyclosporin A, leading to a significant extension of graft survival. Allotrap 07 is a valuable tool for researchers exploring mechanisms of immune tolerance and transplant biology. -
MHC Peptide
SEIDLILGY is a nonapeptide that acts as a ligand for major histocompatibility complex class I (MHC) molecules, derived from mouse sources. This compound is primarily used to stimulate sensory neurons expressing the vomeronasal receptor V2rf2, facilitating studies in neural signaling and sensory processing. Its unique properties make it an invaluable tool for research in neurobiology and immunology. -
Melanoma Antigen-Derived Peptide
VLPDVFIRCV is a melanoma antigen-derived peptide that targets MHC-I class molecules. It has been shown to induce cytotoxic T lymphocytes (CTLs) capable of specifically lysing T2 cells pre-loaded with this peptide in chromium release assays. While VLPDVFIRCV does not activate immune responses against natural tumor cells, it is valuable for vaccine design research and studies focused on immune modulation in melanoma. -
HLA-A*0201-binding Peptide
Adipophilin-derived peptide is an HLA-A*0201-binding peptide that plays a crucial role in immune recognition and response. This peptide is particularly relevant in cancer research, as it may facilitate the study of tumor-associated antigens and their interactions with the immune system. Its application in immunotherapy and vaccine development makes it a valuable reagent for advancing cancer immunology studies.
