Catalog No.
Product Name
Application
Product Information
Citations
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IFNAR
IFN-α Receptor Recognition Peptide 1 specifically targets the IFN-α receptor (IFNAR), facilitating the interaction between interferon and its receptor. This peptide plays a crucial role in modulating immune responses, making it valuable for research in immunology and virology. It can be utilized to study signaling pathways associated with interferon signaling, as well as in the development of therapeutic strategies against viral infections and autoimmune diseases. -
Peptide
MBP (83-99) is a peptide that targets the immunodominant epitope of myelin basic protein (MBP). This peptide is essential for the study of T cell responses, particularly in the context of multiple sclerosis research, as it stimulates the proliferation of T cells and the secretion of interferon-gamma (IFN-γ). It serves as a valuable tool for investigating autoimmune mechanisms and T cell immunology. -
KRAS G12C Peptide
KRAS G12C Peptide specifically targets the KRAS G12C oncogenic mutation, derived from the Kirsten rat sarcoma virus (KRAS) gene. This peptide elicits immune responses, including the secretion of IFN-γ and enhanced cytotoxicity, making it a valuable tool for investigating the immune dynamics against KRAS G12C-mutant tumors. It is particularly applicable in cancer research focused on developing immunotherapies and understanding tumor-immune interactions. -
Bioactive Peptide
IRAK-4 Peptide substrate (IRAK-1 residues 360-380) is a bioactive peptide specifically designed to serve as a substrate for Interleukin-1 Receptor-Associated Kinase 4 (IRAK-4). This peptide facilitates the study of IRAK-4's role in signal transduction pathways associated with inflammatory responses. It is suitable for applications in cellular signaling research, particularly in the context of immune system studies and cytokine signaling. -
Peptide Substrate
Cbz-Lys-Arg-pNA is a peptide substrate designed for enzyme assays, featuring p-nitroaniline (pNA) as a chromogenic reporter group. This compound is extensively utilized in the characterization of serine proteases such as thrombin, plasmin, factor Xa, and kallikrein. Its ability to generate a measurable color change upon enzymatic cleavage makes it a valuable tool in biochemical research and diagnostic applications. -
Bioactive Peptide
OVA-T4 Peptide (SIITFEKL) is a bioactive peptide variant of the ovalbumin epitope (OVA (257-264)), known for its binding to H-2Kb MHC class I molecules. This peptide exhibits comparable binding strength to H-2Kb but demonstrates significantly reduced affinity for the OT-I TCR. OVA-T4 Peptide is useful in research focused on T cell responses and MHC-TCR interactions, making it valuable for the study of immunological mechanisms and peptide-MHC complex dynamics. -
Peptide
OVA peptide is a class I (Kb)-restricted peptide epitope derived from ovalbumin, associated with the major histocompatibility complex (MHC) molecule H-2Kb in mice. This peptide plays a crucial role in immune response studies, particularly in allergy research, where it serves as a model antigen. Its ability to elicit specific T cell responses makes OVA peptide a valuable tool for understanding immune mechanisms and developing therapeutic strategies in allergy and immunology. -
Polypeptide
Gp100 (25-33), human is a polypeptide fragment comprising amino acids 25-33 of the human melanoma antigen. This 9-amino acid epitope is restricted by MHC class I H-2Db and elicits a specific T cell response due to its immunogenic properties. Gp100 (25-33), human is valuable for cancer research, particularly in studies focused on melanoma and T cell-mediated immune responses. -
Ras Inhibitor
Ras Inhibitory Peptide (VPPPVPPRRR) is a specific inhibitor of Ras proteins, known for its antitumor activity. This peptide disrupts Ras signaling pathways, which are critical for cell growth and proliferation, making it a valuable tool in cancer research. Its ability to modulate Ras activity allows for the investigation of therapeutic strategies targeting oncogenic Ras mutations. -
Peptide
Rac1 Inhibitor W56 is a peptide that targets Rac1 by mimicking residues 45-60 of the protein. This inhibitor effectively disrupts the interaction between Rac1 and guanine nucleotide exchange factors such as TrioN, GEF-H1, and Tiam. Rac1 Inhibitor W56 is valuable for research applications focused on studying the role of Rac1 in cellular processes, including migration, invasion, and cytoskeletal dynamics. -
Immune Potentiator
KRAS G13D peptide, 25 mer, is an immune potentiator derived from a KRAS oncogene mutation. This peptide plays a crucial role in stimulating immune responses and can be utilized in the development of KRAS-targeted vaccines. Its application in cancer immunotherapy research makes it a valuable tool for studying the interactions between mutated KRAS and immune system activation. -
Tool Peptide
Myr-Arf1(2–17) is a sarcosinated peptide designed to mimic the localization and functionality of Arf1 protein at the cell membrane. This tool peptide serves as an important research reagent for investigating the desensitization mechanisms of the luteinizing hormone/chorionic gonadotropin receptor (LH/CGR). Its utility in studying cellular signaling pathways provides valuable insights into receptor dynamics and function. -
Relaxin Peptide
Relaxin H3 (human) is a relaxin peptide that primarily targets the RXFP1 receptor. It exhibits potent antifibrotic properties, making it valuable for research focused on fibrosis and tissue remodeling. This compound is useful in studying the pathways involved in extracellular matrix regulation and may have implications for therapeutic strategies in fibrotic diseases. -
Neuropeptide
Cortistatin 14 is a neuropeptide that primarily targets somatostatin receptors (SSTRs) and the ghrelin receptor. This compound exhibits neuronal depressant and sleep-modulating properties, making it vital for studies related to sleep physiology and neural signaling. Additionally, its presence alongside GABA in the cortex and hippocampus highlights its role in modulating neurotransmission and potential applications in researching sleep disorders and neurodegenerative conditions. -
Somatostatin Neuropeptide
Cortistatin-17 (human) is a somatostatin neuropeptide that modulates neuroendocrine signaling through its interaction with somatostatin receptors. Its biological activities include the regulation of endocrine and exocrine functions, as well as potential anti-inflammatory effects. This peptide is valuable for research applications related to cancer, inflammation, autoimmunity, fibrosis, and pain. -
Somatostatin Neuropeptide
Cortistatin-29 (human) is a somatostatin neuropeptide that modulates a variety of biological functions by interacting with somatostatin receptors. This compound exhibits key biological activities, including anti-inflammatory effects and regulation of pain pathways, making it relevant for research applications in cancer, inflammation, autoimmunity, fibrosis, and pain management. Its unique biological profile allows for exploration of potential therapeutic strategies targeting these conditions. -
Neuroavtive Peptide
[Tyr11]-Somatostatin is a neuroactive peptide that modulates various physiological processes by targeting somatostatin receptors. This compound is essential for studying the role of neuroactive substances in retinal physiology and their implications in various neurobiological research applications. Its use in proteomics research contributes to a deeper understanding of neuronal signaling pathways and potential therapeutic targets. -
Neuropeptide
Cortistatin-29 is a rat neuropeptide that targets somatostatin receptors (SSTRs) with high affinity, exhibiting IC50 values of 2.8 nM for SSTR1, 7.1 nM for SSTR2, 0.2 nM for SSTR3, 3.0 nM for SSTR4, and 13.7 nM for SSTR5. This compound is known to alleviate neuropathic pain and demonstrates anti-fibrotic properties. Its diverse biological activities make it a valuable tool for research in neurobiology and fibrosis-related studies. -
Tetradecapeptide
[D-Trp8] Somatostatin-14 is a tetradecapeptide analog of somatostatin that exhibits enhanced potency compared to its native counterpart. This compound primarily targets somatostatin receptors, influencing various physiological processes including hormonal secretion and cell proliferation. It is utilized in research applications focusing on neuroendocrine regulation and the therapeutic potential of somatostatin analogs in treating conditions such as acromegaly and neuroendocrine tumors. -
Urotensin II Anague
Urotensin II-related peptide is an analog of human urotensin II, exhibiting high affinity for the urotensin II receptor (UT). This peptide plays a significant role in cardiovascular regulation and may influence vascular smooth muscle contraction. It is commonly utilized in research focused on cardiovascular diseases, neurobiology, and the study of peptide receptor interactions. -
urotensin-II Receptor Antagonist Peptide
Urantide is a selective and competitive antagonist of the urotensin-II (UT) receptor, exhibiting a pKB of 8.3. This peptide effectively inhibits human urotensin-II (hU-II)-induced contractions in rat thoracic aorta ex vivo. Urantide is valuable for investigating the (patho)physiological roles of hU-II in the mammalian cardiovascular system, making it an important tool for related research applications. -
Cyclic Peptide
Urotensin II, teleost fish, is a cyclic peptide that plays a significant role in regulating cardiovascular and endocrine functions in teleost species. This peptide is involved in vasoconstriction and modulation of blood pressure, making it a valuable tool for research into fish physiology and neuroendocrine signaling. Its unique biological activities provide insights into the evolutionary adaptations of stress responses in aquatic environments. -
Antidiuretic Peptide
F992 is an analogue of vasopressin, also known as antidiuretic hormone, targeting the antidiuretic peptide pathways. This compound exhibits significant activity in modulating water reabsorption in the kidneys and has applications in research focused on fluid balance, blood pressure regulation, and related endocrine functions. F992 serves as a valuable tool for investigating the physiological and pathological roles of antidiuretic peptides in various biological systems. -
HLA-A1-restricted T-cell Epitope
AIM2-derived decapeptide is an HLA-A1-restricted T-cell epitope that targets the AIM2 pathway. This peptide plays a significant role in immune response modulation and has potential applications in the study of melanoma. Researchers can utilize this decapeptide to investigate T-cell responses and the mechanisms underlying tumor immunity. -
BCL6 Inhibitor
SMRT peptide is a BCL6 inhibitor that functions by binding to the BTB domain of BCL6, thereby enhancing its transcriptional repression activity. This compound serves as a valuable tool for studying protein-protein interactions related to BCL6 function in various biological processes. Research applications include investigations into the role of BCL6 in cancer and other diseases where transcriptional regulation is critical. -
Bioactive Peptide
CFP10 (71–85) is a bioactive peptide that stimulates the production of interferon-gamma (IFN-γ) and enhances cytotoxic T lymphocyte (CTL) activity in both CD4+ and CD8+ T cells. It is particularly effective in individuals expressing various MHC class II and class I molecules. This peptide is valuable for research applications focused on immune response modulation and T cell activation. -
CD47/SIRPα blocking peptide
Pep-20 is a CD47/SIRPα blocking peptide that inhibits the interaction between CD47 and SIRPα, demonstrating KD values of 2.91 μM for human CD47 and 3.63 μM for mouse CD47. With IC50 values of 24.56 μM and 12.03 μM, respectively, for blocking these interactions, Pep-20 exhibits significant anti-tumor activity. This peptide is useful in research applications focused on immune evasion in cancer therapies and interactions within the tumor microenvironment. -
Thrombospondin-1-Derived Peptide
Thrombospondin-1 (1016-1021) is a peptide derived from Thrombospondin-1 that lacks CD47-binding activity. This truncated peptide is useful for studying the regulatory roles of Thrombospondin-1 in cellular processes such as angiogenesis and cell adhesion. Its applications in research include investigations into the modulation of immune responses and the exploration of potential therapeutic targets in various diseases. -
Muramil-dipeptide Analogue
Glucosaminylmuramyl dipeptide (GMDP) is a synthetic analogue of muramil-dipeptide, functioning primarily as an inhibitor of 5'-nucleotidase activity. This compound exhibits significant antitumor effects and is valuable in the study of sepsis. Researchers can utilize GMDP to investigate immune responses and therapeutic interventions in oncological and inflammatory contexts. -
Tetrapeptide
Amogastrin is a tetrapeptide that primarily stimulates gastric extraction of 99mTc pertechnetate. This compound plays a significant role in the imaging of gastric mucosal diseases, facilitating enhanced diagnostic capabilities. Additionally, Amogastrin is involved in the stimulation of prostate hormone production, making it relevant for research in endocrinology and gastrointestinal studies. -
Prostate Specific Antigen 1 Peptide
PSA1 (141-150) is a peptide derived from Prostate Specific Antigen 1, targeting prostate cancer cells. This peptide is utilized in immunotherapy research to investigate immune responses and develop potential treatment strategies for prostate cancer. Its role in enhancing immune recognition makes it a valuable tool in cancer studies. -
PAR Agonist
PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a selective agonist for proteinase-activated receptor-4 (PAR-4), demonstrating no activity on PAR-1 or PAR-2. This compound is instrumental in studies investigating the role of PAR-4 in various cellular processes, including apoptosis and inflammation. Its biological activity can be effectively countered by a specific PAR-4 antagonist, allowing for detailed examination of PAR-4-mediated signaling pathways in research applications. -
Bioactive Peptide
TFLLRN-NH2 is a bioactive peptide that acts as an agonist for protease-activated receptor 1 (PAR-1). This peptide is involved in various biological processes, including thrombosis and inflammation. Its use in research facilitates the study of PAR-1 signaling pathways and their implications in cardiovascular and other diseases. -
Thrombin Receptor Activating Peptide
TRAP-7 is a thrombin receptor (PAR) activating peptide that functions by stimulating total inositol phosphate (IP) accumulation, as well as the phosphorylation of a specific endogenous substrate for activated protein kinase C (PKC). This compound is valuable in the study of signaling pathways related to thrombosis and cardiovascular diseases, providing insights into PAR-mediated cellular responses and potential therapeutic interventions. -
Bioactive Peptide
YFLLRNP is a bioactive peptide that acts as a partial agonist of the protease-activated receptor 1 (PAR-1). At low concentrations, it selectively activates the G12/13 signaling pathway without triggering Gq or Gi pathways. This unique signaling profile makes YFLLRNP valuable for research into cellular mechanisms influenced by PAR-1 and for studies on cardiovascular and inflammatory responses. -
PAR-3 Agonist Peptide
Protease-Activated Receptor-3 (PAR-3) (1-6), human is a peptide that functions as an agonist for the proteinase-activated receptor 3 (PAR-3). This compound is involved in various biological processes, including inflammation and cell signaling pathways. It is frequently utilized in research to explore the physiological roles of PAR-3 in cellular responses and disease mechanisms. -
PAR-2 Negative Control Peptide
LRGILS-NH2 is a reverse-sequence peptide serving as a negative control for protease-activated receptor-2 (PAR-2) studies. This inactive version allows researchers to discern the specific effects of PAR-2 activation when used alongside the active peptide SLIGRL-NH2. LRGILS-NH2 is critical for validating experimental results in various biological assays involving PAR-2 signaling pathways. -
Bioactive Peptide
SFNGGP-NH2 is a bioactive peptide that targets Protease-Activated Receptors (PARs), specifically PAR-3. This peptide plays a role in modulating thrombin signaling pathways and has been implicated in itch responses, particularly in cutaneous mast cells. Studies suggest that while PAR-3 does not induce itching independently, its co-expression with PAR-4 enhances thrombin activity, indicating its role as a cofactor in transmembrane signaling. This makes SFNGGP-NH2 valuable for research on itch mechanisms and thrombin-related physiological processes. -
Bone Forming Peptide
pTH-Related Protein (1-37) is a bone-forming peptide that serves as a functional analogue of parathyroid hormone-related protein (pTHrP). This peptide plays a crucial role in the physiological regulation of bone formation and remodeling. Its utilization in research encompasses studies on bone health, osteoporosis, and other metabolic bone disorders, making it a valuable tool for exploring therapeutic interventions in skeletal-related conditions in human, mouse, and rat models. -
Polypeptide
Osteostatin (1-5) amide is a polypeptide derived from the C-terminal region of parathyroid hormone-related protein (PTHrP). It functions primarily by inhibiting bone resorption, making it an important tool in studies of bone metabolism and related disorders. This fragment is relevant for research applications involving bone density regulation and osteoclast activity across various species, including human, bovine, canine, equine, murine, rabbit, and rat models. -
Ras Peptide
G12 (Ras 5-17) is a synthetic wild-type Ras peptide composed of amino acids 5-17 (KLVVVGAGGVGKS). This peptide serves as a valuable control for studies involving mutation variants of Ras, such as V12. Research applications include investigating Ras signaling pathways and exploring the functional impacts of mutations in cancer biology and therapeutic development. -
Peptide
KRAS G12D (8-16) is a peptide derived from the mutant KRAS G12D protein, known for its role in oncogenic signaling pathways. This peptide serves as a valuable tool for research into KRAS-related cancers, facilitating studies of protein interactions, signaling mechanisms, and the development of targeted therapies. Its application in various assays aids in unraveling the complexities of KRAS mutations in tumor biology. -
KRAS G12D targeting peptide
KLVVVGADGVGKSALTI is a peptide specifically designed to target the KRAS G12D mutation. This peptide plays a crucial role in tumor biology research by facilitating the study of KRAS-mediated signaling pathways and their implications in cancer progression. Its application in experimental models aids in understanding the therapeutic potential of targeting KRAS in oncological studies. -
Nuclear Localization Signal Peptide
BIMAX2 is a high-affinity nuclear localization signal (NLS) peptide that acts by competitively binding to importin α, thereby inhibiting the interaction between classical nuclear localization signal-cargo proteins and importin α. This mechanism allows for the investigation of the role of RBBP4 in regulating nuclear import efficiency and its impact on cell senescence. BIMAX2 is a valuable tool for studies in cell biology, particularly in the context of nuclear transport and aging-related research. -
Neuropeptide Y Y2 Receptor
JNJ-5207787 is a selective nonpeptidic antagonist of the neuropeptide Y Y2 receptor, designed to penetrate the blood-brain barrier effectively. It demonstrates strong inhibition of peptide YY (PYY) binding, with pIC50 values of 7.0 and 7.1 for the human and rat Y2 receptors, respectively. This compound exhibits over 100-fold selectivity against human Y1, Y4, and Y5 receptors, making it a valuable tool for research into neuropeptide Y signaling pathways and their roles in various physiological processes. -
Neuropeptide
N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) is a selective agonist of the neuropeptide Y Y2 receptor. This compound has been shown to attenuate cardiac vagal activity in anesthetized rat models, making it a valuable tool for studying cardiac function and neuropeptide signaling. Its application in research can provide insights into cardiovascular regulation and potential therapeutic targets for heart-related conditions. -
Neuropeptide Y Receptor Antagonist
Peptide YY (PYY) (3-36), porcine is a neuropeptide Y receptor antagonist that plays a significant role in appetite regulation. By modulating the activity of the neuropeptide Y system, it is utilized in research related to metabolic disorders and feeding behavior. This peptide is valuable for studies investigating energy homeostasis and its implications in obesity and appetite control. -
NPY-5 Receptor Antagonist
Neuropeptide Y5 receptor ligand-1 is a potent antagonist of the neuropeptide Y5 (NPY-5) receptor. This carbazole derivative is utilized in research applications focused on the role of NPY-5 in various physiological processes, including regulation of appetite, anxiety, and circadian rhythms. By inhibiting NPY-5 receptor activity, it provides valuable insights into neuropeptide signaling pathways and their implications in metabolic and neurobehavioral disorders. -
Y2 Receptor Agonist
Peptide YY (13-36) is a selective agonist of the Y2 receptor subtype, targeting the neuropeptide Y (NPY) system. This peptide plays a significant role in regulating appetite, energy balance, and gastrointestinal function. It is widely utilized in research applications focused on metabolic disorders, obesity, and neurobiology across various species, including canine, mouse, porcine, and rat models. -
Y1 Agonist
(Leu31,Pro34)-Peptide YY (human) is a potent and selective agonist for the neuropeptide Y receptor subtype Y1, exhibiting a dissociation constant (KD) of 1.0 nM. This derivative of Peptide YY is utilized in research applications studying metabolic regulation, appetite control, and gastrointestinal functions. Its high specificity makes it an invaluable tool for investigating the physiological roles of Y1 receptors in various biological processes.
