Catalog No.
Product Name
Application
Product Information
Citations
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Neuropeptide
Zebrafish Kisspeptin-1 is a key neuropeptide that primarily targets the regulation of gonadotropin-releasing hormone (GnRH) release. This peptide plays a crucial role in the modulation of the reproductive system in zebrafish. It is widely utilized in research related to reproductive biology, neuroendocrine signaling, and developmental studies, providing insights into the mechanisms underlying reproduction and hormonal regulation. -
Antireproductive Tripeptide
Threonyl-seryl-lysine is an antireproductive tripeptide that exhibits antigonadotropic activity by binding to luteinizing hormone-releasing hormone (LHRH) at a specific site within residues 2-5. This compound is instrumental in the study of reproductive biology, particularly in understanding the regulatory mechanisms of gonadotropin secretion. Its ability to modulate hormone levels makes it a valuable tool for research applications related to fertility and reproductive health. -
Polypeptide
(Des-Pyr1)-LHRH is a modified polypeptide designed for research into hormone receptor interactions. It plays a crucial role in the study of gonadotropin-releasing hormone (GnRH) and has applications in peptide screening for protein interactions, functional assays, and epitope mapping. This reagent is particularly valuable in agent research and development, contributing to advancements in reproductive biology and endocrinology. -
GAP
GnRH Associated Peptide (25-53), human targets gonadotropin-releasing hormone (GnRH) and serves as a crucial fragment of the human GnRH-associated peptide (hGAP-25-53). This peptide is suitable as an immunogen for the generation of specific antiserum including MC-1, MC-2, and MC-3. By connecting to the luteinizing hormone-releasing hormone (LH-RH) sequence via a three-amino acid processing site, it plays a significant role in reproductive hormone regulation and offers valuable applications in endocrinology and reproductive biology research. -
Peptide Hormone
(Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH is a synthetic peptide hormone designed to interact with the luteinizing hormone-releasing hormone (LHRH) receptor. This compound exhibits key biological activities related to hormone regulation and neuroendocrine function. Its applications include research in reproductive biology, endocrine signaling pathways, and potential therapeutic investigations in hormone-related disorders. -
Active Peptide
(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) is an active peptide that targets the luteinizing hormone-releasing hormone (LHRH) receptor. This compound is known for its role in regulating gonadotropin release and influencing reproductive hormone signaling. It is valuable for biochemical studies related to reproductive biology, neuroendocrine signaling, and the development of therapeutic agents targeting reproductive disorders. -
Polypeptide
Glp-His-Pro-Gly-NH2 is a polypeptide that functions primarily as a stimulant for gonadotrophin release, specifically luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This peptide plays a crucial role in reproductive physiology and is valuable in research applications related to hormone regulation, fertility studies, and endocrine system investigations. Its ability to modulate hormone secretion makes it a useful reagent for studying pituitary function and related hormonal pathways. -
Polypeptide
LHRH (1-5) free acid is a polypeptide derived from the cleavage of luteinizing hormone-releasing hormone at the Tyr55-Gly66 site. This compound can be further processed into LHRH (1-3) and LHRH (4-5) fragments through the action of Angiotensin-converting enzyme. It serves as a valuable tool for studying neuroendocrine signaling and reproductive biology, facilitating research into hormone regulation and related physiological processes. -
Hormone Peptide
Human follicular gonadotropin releasing peptide (hF-GRP) is a hormone peptide that primarily stimulates the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. This peptide plays a crucial role in regulating reproductive processes by enhancing gonadotropin release. hF-GRP is valuable for research applications involving reproductive endocrinology, fertility studies, and the regulation of hormonal pathways. -
GAP
GnRH Associated Peptide (1-24), human is a fragment of the human gonadotropin-releasing hormone-associated peptide (GAP) comprising residues 1-24. This peptide is linked to the luteinizing hormone-releasing hormone (LH-RH) sequence via a three-amino-acid processing site, playing a critical role in reproductive hormone regulation. It is primarily utilized in research to study the mechanisms of gonadotropin release and the modulation of fertility-related pathways. -
Peptide
(Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog targeting gonadotropin-releasing hormone receptors. This peptide exhibits significant biological activity in modulation of hormonal signaling pathways, making it valuable for research in reproductive biology and endocrine regulation. It is particularly useful for studies aimed at understanding potentiation and inhibition of luteinizing hormone release in various biological systems. -
Polypeptide
(D-Leu6)-LHRH (1-8) is a synthetic polypeptide known for its role as a gonadotropin-releasing hormone analogue, primarily targeting the pituitary gland. It exhibits significant biological activity by modulating hormonal release, making it valuable in studies of reproductive physiology and endocrinology. This reagent is widely utilized in peptide screening for protein interactions, functional analysis, and epitope mapping, advancing research in therapeutic agent development. -
Peptide
(D-His2)-Goserelin is a peptide analog derived from Goserelin, which mimics the structure of gonadotropin-releasing hormone (GnRH/LHRH). This compound serves primarily as an agonist of GnRH receptors, influencing the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Its biological activity makes it valuable in research focused on reproductive biology, endocrinology, and fertility treatments. -
Polypeptide
(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH is a synthetic polypeptide that serves as a potent analog of Luteinizing Hormone-Releasing Hormone (LHRH), targeting the neuroendocrine system. It exhibits significant biological activity in regulating hormone release, making it valuable for research applications related to reproductive biology and endocrine function. This reagent can facilitate peptide screening studies for immunoassays, protein interactions, and functional analyses, particularly in the context of drug development and therapeutic interventions. -
Polypeptide
(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH is a synthesized polypeptide designed to modulate gonadotropin release hormone (GnRH) signaling pathways. This compound exhibits significant biological activity in influencing reproductive hormone regulation, making it a valuable tool in endocrinology research. It is particularly applicable in studies focused on peptide interactions, functional analysis, and epitope mapping, contributing to the advancement of therapeutic agents in reproductive health and related fields. -
Polypeptide
(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH is a synthesized polypeptide designed to target luteinizing hormone-releasing hormone (LHRH) receptors. This compound exhibits biological activity relevant to the modulation of reproductive hormone pathways, making it valuable in research focused on endocrine function and signaling. It is particularly useful for applications in peptide screening, protein interaction studies, and functional analysis within the context of agent development in reproductive biology. -
Polypeptide
(D-Ser6,Azagly10)-LHRH is a modified polypeptide that targets the luteinizing hormone-releasing hormone (LHRH) receptor. This compound exhibits significant activity in regulating reproductive hormone release and is utilized in research applications focusing on reproductive biology, endocrinology, and peptide-based therapies. Its utility in peptide screening enables the identification and validation of active peptides, facilitating studies on protein interactions and functional analyses in various biological contexts. -
Polypeptide
(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH is a synthetic polypeptide derivative that serves as a potent agonist of the luteinizing hormone-releasing hormone (LHRH) receptor. This compound is vital for research in endocrinology, particularly for studies investigating reproductive physiology and the regulation of gonadotropin release. Its application in peptide screening enables the identification of active peptides, offering insights into protein interactions and functional analyses within the field of pharmaceutical development. -
Polypeptide
(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH is a synthetic polypeptide designed to interact with gonadotropin-releasing hormone receptors. This compound exhibits bioactivity relevant to the modulation of reproductive hormones, making it valuable in studies focused on reproductive biology and endocrine regulation. Its applications include protein interaction studies, functional assays, and epitope mapping, particularly in the context of agent research and development. -
Polypeptide
(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH is a synthetic polypeptide that targets luteinizing hormone-releasing hormone (LHRH) receptors. It exhibits notable biological activity in modulating hormone release, making it a valuable tool in endocrinology research. Applications include protein interaction studies, functional analysis, and epitope mapping, particularly in the development of therapeutic agents and understanding hormonal regulation. -
Polypeptide
(D-Leu6,Pro-NHEt9)-LHRH (4-9) is a polypeptide designed for applications in peptide screening. This compound serves as a valuable tool for identifying active peptides primarily through immunoassay methodologies. It is particularly useful for studying protein interactions, conducting functional analyses, and performing epitope screenings, making it relevant in agent research and development within the life sciences. -
Signature Peptide
IYPTNGYTR is a deamidation-sensitive signature peptide derived from Trastuzumab, specifically designed to provide insights into the metabolic processes of this therapeutic antibody. Its detection allows for the monitoring of Trastuzumab metabolism in vivo, facilitating studies related to drug efficacy and stability. This peptide is valuable for researchers investigating antibody pharmacokinetics and therapeutic applications in oncology. -
Bioactive Peptide
MeOSuc-AAPV-AFC is a bioactive peptide that serves as a highly specific substrate for neutrophil elastase. This compound exhibits fluorescence with an excitation/emission wavelength of 380/500 nm, enabling sensitive detection and quantification in research applications. It is primarily utilized in studies focusing on proteolytic activity related to inflammation and immune response. -
Dipeptide condensation product
L-Leucyl-L-Leucine methyl ester hydrobromide is a dipeptide condensation product targeting lymphocytes with cytotoxic potential. This compound selectively induces lymphocyte elimination while also triggering endolysosomal pathway stress. It is utilized in research applications focused on immune response modulation and cellular stress mechanisms. -
Polypeptide
YIGSR (Laminin Fragment 929-933) is a polypeptide that serves as an inhibitor of tumor growth and metastasis in leukemia cells. It exhibits specific binding to the 67kDa laminin receptor, influencing the expression of endothelial nitric oxide synthase (eNOS) in endothelial cells. This peptide is valuable for research focused on leukemia and related pathophysiological mechanisms. -
SPSB2-iNOS Inhibitor
SPSB2-iNOS inhibitory cyclic peptide-1 is a potent inhibitor targeting the interaction between SPSB2 and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity (KD) of 4.4 nM. This cyclic peptide demonstrates resistance to proteolytic degradation by pepsin, trypsin, and α-chymotrypsin, ensuring stability in biological environments. Additionally, it maintains stability in human plasma and oxidative conditions, making it a valuable tool for studying iNOS-related pathways in inflammation and other biological processes. -
Control Peptide
Tat-NR2Baa is a control peptide designed to evaluate the specificity of Tat-NR2B9c. This inactive variant features a double-point mutation in the COOH terminal tSXV motif, which prevents binding to the postsynaptic density protein PSD-95. While it retains structural similarity to Tat-NR2B9c, Tat-NR2Baa does not disrupt the PSD-95/NMDAR interaction. It serves as a valuable tool in studies investigating the roles of PSD-95 in NMDAR signaling pathways and related neurophysiological research. -
NO Synthase Activator
eNOS pT495 decoy peptide is a specific inhibitor designed to disrupt the phosphorylation at T495, thereby promoting eNOS uncoupling and preventing mitochondrial redistribution. This peptide serves as a valuable tool in the investigation of nitric oxide synthase activation, particularly in studies related to ventilator-induced lung injury and associated pathophysiological mechanisms. Its role in modulating eNOS activity makes it essential for exploring therapeutic approaches in respiratory and cardiovascular research. -
Antitumor Peptide
YIGSR-Lys(N3) is an antitumor peptide that targets cellular interactions with laminin I through the inhibition of the 67-kDa laminin-binding protein, effectively hindering the growth and metastasis of leukemic cells. Additionally, it modulates the shear-induced expression of endothelial nitric oxide synthase in laminin cells. This compound serves as a click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition and strain-promoted alkyne-azide cycloaddition reactions with alkyne-containing or DBCO/BCN-bearing molecules, respectively. Its versatile reactivity makes it valuable for research in both cancer biology and chemical biology applications. -
SPSB2-iNOS Inhibitor
SPSB2-iNOS inhibitory cyclic peptide-2 is a selective inhibitor of the interaction between SPSB2 and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity with a KD of 21 nM. This cyclic peptide is both reduction-resistant and oxidatively stable, making it suitable for various biological assays. Its ability to inhibit SPSB2-iNOS interactions positions it as a valuable tool in research focused on nitric oxide signaling and related pathophysiological processes. -
SPSB2-iNOS Inhibitor
SPSB2-iNOS inhibitory cyclic peptide-3 is a selective inhibitor targeting the interaction between SPSB2 and inducible nitric oxide synthase (iNOS). This compound binds to the SPSB2 site on iNOS with a dissociation constant (KD) of 7 nM. It demonstrates significant biological activity in modulating nitric oxide production and has potential applications in studies related to inflammation and oxidative stress. -
Antidepressant Peptide
Tat-SERT-15C is an antidepressant peptide that modulates the serotonin transporter (SERT) and nitric oxide synthase (nNOS) interaction. This peptide decreases the SERT-nNOS complex, leading to enhanced SERT expression. Tat-SERT-15C has demonstrated efficacy in reversing depression-like behaviors induced by chronic unpredictable mild stress, making it a valuable tool for research into the mechanisms of depression and potential therapeutic interventions. -
Thrombin Peptide
TP508 is a 23-amino acid nonproteolytic thrombin peptide that selectively targets the receptor-binding domain of thrombin. It activates endothelial nitric oxide synthase (eNOS) and promotes nitric oxide production in human endothelial cells, facilitating enhanced endothelial cell activation and stem cell recruitment. This molecule is of significant interest for applications in tissue revascularization and regenerative medicine research. -
FOXP3 Inhibitor
Peptide P60 is a potent FOXP3 inhibitor that disrupts the nuclear translocation of FOXP3, thereby decreasing its regulatory effects on NF-κB and NFAT signaling pathways. This action inhibits the immunosuppressive capabilities of regulatory T cells, facilitating the proliferation and activation of effector T cells. Experimental studies have shown that Peptide P60 can induce lymphoproliferative autoimmune syndrome in neonatal ICR mice and diminish the population of CD4+CD25+Foxp3+ T cells in the spleen. Additionally, it enhances the efficacy of peptide vaccines and recombinant adenovirus-based vaccines, making it valuable for research in tumor immunology, viral infections, and autoimmune conditions. -
Osteopontin-derived Peptide
SVVYGLR is an osteopontin-derived peptide that primarily promotes fibroblast differentiation into myofibroblast-like cells and enhances type III collagen production by cardiac fibroblasts. It effectively activates adhesion, migration, and tubule formation in endothelial cells, thereby facilitating angiogenesis and wound healing processes. Additionally, SVVYGLR supports the migration of dermal fibroblasts and keratinocytes, making it a valuable reagent for research in angiogenesis, dermal wounds, and bone regeneration studies. -
PSMA Targeting Peptide
PSMA Targeting Peptide (GRFLTGGTGRLLRIS) is designed to specifically bind to Prostate-Specific Membrane Antigen (PSMA) on prostate cancer cells. This peptide facilitates the targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs, enhancing the efficacy of RNA interference in therapeutic applications. The peptide can be modified by adding polyarginine sequences at the C-terminus, and when labeled with FITC through an aminohexanoic acid linker at the N-terminus, it allows for precise tracking of PSMA interactions in cellular contexts. -
Antioxidant Peptide
Antioxidant Peptide A is a short peptide featuring alternative aromatic or sulfur-containing amino acids, which facilitate its robust radical scavenging capabilities. This peptide exhibits significant antioxidant activity, demonstrating potential in mitigating oxidative stress within cancer cells. It serves as a valuable tool for research applications focused on oxidative damage and cancer biology. -
Anxiolytic Agent
δ-Sleep Inducing Peptide is a neuropeptide that functions as an anxiolytic agent. It exhibits antioxidant properties and plays a critical role in the modulation of sleep and anxiety-related behaviors. This compound is primarily used in research exploring neurobiology, sleep regulation, and mental health disorders. -
9-mer Peptide Probe
AE105 is a 9-mer peptide probe that specifically targets the urokinase-type plasminogen activator receptor (uPAR). It exhibits high-affinity binding to the uPA-binding cavity of uPAR, making it a valuable tool for investigating uPAR-related signaling pathways. This peptide probe is particularly useful in cancer research, aiding in the exploration of tumor progression and metastasis mechanisms. -
Bioactive Peptide
Thrombospondin (TSP-1)-derived CD36 binding motif is a bioactive hexapeptide that targets CD36 and angiostatin. This peptide disrupts cell adhesion and migration by interfering with the interaction between cells and the extracellular matrix. Additionally, it demonstrates the capability to inhibit platelet aggregation and exhibits anti-tumor properties, particularly against colon cancer. Its applications encompass studies of cell adhesion dynamics, platelet function, and potential therapeutic strategies in oncology. -
FKBPL Peptide
AD 01 is a 24-amino acid peptide derived from FKBPL (FK506-binding protein like), targeting the CD44 receptor to exert significant anti-angiogenic effects. By binding to CD44, AD 01 effectively inhibits tumor cell migration in a manner dependent on this receptor. This peptide is valuable for research applications focused on cancer biology, particularly in studies related to angiogenesis and tumor metastasis. -
GPR110 Agonist
GPR110 peptide agonist P12 is an agonist targeting the GPR110 receptor. This peptide significantly enhances the initial rate of G protein GTPγS binding stimulated by GPR110, effectively mimicking natural ligands. By inducing dissociation between the receptor's extracellular domain and its seven transmembrane domains, P12 exposes the β-strand-13/stalk region of the 7TM domain, facilitating G protein signaling activation. This compound is valuable for research into developmental disorders and cancers associated with GPR110 pathways. -
CD63-binding Peptide
CP05 is a CD63-binding peptide that specifically interacts with the exosome surface marker CD63. This interaction facilitates the anchoring of exosomes to target tissues, enhancing in vivo delivery of exosomal payloads. CP05 is useful in research applications focused on drug delivery, therapeutic targeting, and the study of exosome biology. -
Analogue of the Glycopeptide
Glycotriosyl glutamine is a synthetic analogue of Glycopeptide that targets glomerular structures in kidney cells. This compound has been shown to induce focal glomerulonephritis (FGN) in animal models, specifically resulting in the formation of myeloid bodies within podocyte epithelial cells. Its unique properties make it a valuable tool for investigating nephritogenic mechanisms and kidney disease pathology. -
CD36 Peptide
CD36 Peptide P (139-155), Cys conjugated targets the CD36 protein and serves as a crucial tool for studying its function. This Cys-conjugated peptide is effective in inhibiting the immunoadsorption of CD36 by the OKM5 antibody, making it valuable for research applications focused on immune responses and metabolic processes. The peptide can aid in the investigation of CD36-related pathways and its role in various biological contexts. -
Bioactive Peptide
Tumour-associated MUC1 epitope is a bioactive peptide targeting the MUC1 mucin, a type I transmembrane glycoprotein characterized by a highly glycosylated extracellular domain composed of repeated 20 amino acid units. This epitope is overexpressed on the surface of various human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma. Its frequent upregulation in cancer cells renders the MUC1 epitope a valuable target for the development of immunotherapeutic strategies, facilitating advancements in cancer treatment research. -
CD36 Peptide
CD36 Peptide P (93-110), Cys conjugated specifically targets CD36, a multifunctional receptor involved in cellular adhesion and lipid metabolism. This peptide has been shown to block the binding of CD36 to immobilized thrombospondin, thereby providing valuable insights into CD36-mediated pathways. Additionally, it partially inhibits collagen-induced platelet aggregation, making it useful for research applications related to cardiovascular function and cell signaling. -
Antigen Peptide Segment
[Gln144]-PLP (139-151) is an experimental antigen peptide segment designed to engage T-cell receptors (TCR) and activate T cells. This activation plays a crucial role in examining the immune response to both autoantigens and cross-reactive non-autoantigens. Its applications extend to the investigation of the underlying mechanisms involved in the regulation of autoimmune diseases, providing insights into potential therapeutic approaches. -
p32-targeting Peptide
LinTT1 peptide is a tumor-penetrating peptide that specifically targets the p32 (gC1qR) receptor. This peptide demonstrates enhanced cellular uptake in peritoneal carcinoma (PC) cells, facilitating mitochondrial entry and promoting targeted drug delivery. When conjugated with iron oxide nanoworms, LinTT1 forms a nanocarrier that significantly enhances tumor penetration and targeting in vivo. Additionally, when combined with the pro-apoptotic peptide [D(KLAKLAK)2], LinTT1-functionalized nanocarriers exhibit pronounced tumor suppression in mouse models of peritoneal cancer, highlighting its potential as an effective carrier in cancer research. -
VCAM1 Binding Peptide
VCAM1 Binding Peptide is designed to specifically bind to Vascular Cell Adhesion Molecule 1 (VCAM1). This peptide, with the sequence VHPKQHRGGSKGC, serves as a valuable tool for investigating VCAM1's role in cellular adhesion and inflammatory processes. It is commonly used in research applications focused on vascular biology, immunology, and disease models related to cardiovascular conditions.
