Catalog No.
Product Name
Application
Product Information
Citations
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Polypeptide
(D-Ser6,Azagly10)-LHRH is a modified polypeptide that targets the luteinizing hormone-releasing hormone (LHRH) receptor. This compound exhibits significant activity in regulating reproductive hormone release and is utilized in research applications focusing on reproductive biology, endocrinology, and peptide-based therapies. Its utility in peptide screening enables the identification and validation of active peptides, facilitating studies on protein interactions and functional analyses in various biological contexts. -
Polypeptide
(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH is a synthetic polypeptide derivative that serves as a potent agonist of the luteinizing hormone-releasing hormone (LHRH) receptor. This compound is vital for research in endocrinology, particularly for studies investigating reproductive physiology and the regulation of gonadotropin release. Its application in peptide screening enables the identification of active peptides, offering insights into protein interactions and functional analyses within the field of pharmaceutical development. -
Polypeptide
(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH is a synthetic polypeptide designed to interact with gonadotropin-releasing hormone receptors. This compound exhibits bioactivity relevant to the modulation of reproductive hormones, making it valuable in studies focused on reproductive biology and endocrine regulation. Its applications include protein interaction studies, functional assays, and epitope mapping, particularly in the context of agent research and development. -
Polypeptide
(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH is a synthetic polypeptide that targets luteinizing hormone-releasing hormone (LHRH) receptors. It exhibits notable biological activity in modulating hormone release, making it a valuable tool in endocrinology research. Applications include protein interaction studies, functional analysis, and epitope mapping, particularly in the development of therapeutic agents and understanding hormonal regulation. -
Polypeptide
(D-Leu6,Pro-NHEt9)-LHRH (4-9) is a polypeptide designed for applications in peptide screening. This compound serves as a valuable tool for identifying active peptides primarily through immunoassay methodologies. It is particularly useful for studying protein interactions, conducting functional analyses, and performing epitope screenings, making it relevant in agent research and development within the life sciences. -
Signature Peptide
IYPTNGYTR is a deamidation-sensitive signature peptide derived from Trastuzumab, specifically designed to provide insights into the metabolic processes of this therapeutic antibody. Its detection allows for the monitoring of Trastuzumab metabolism in vivo, facilitating studies related to drug efficacy and stability. This peptide is valuable for researchers investigating antibody pharmacokinetics and therapeutic applications in oncology. -
Bioactive Peptide
MeOSuc-AAPV-AFC is a bioactive peptide that serves as a highly specific substrate for neutrophil elastase. This compound exhibits fluorescence with an excitation/emission wavelength of 380/500 nm, enabling sensitive detection and quantification in research applications. It is primarily utilized in studies focusing on proteolytic activity related to inflammation and immune response. -
Dipeptide condensation product
L-Leucyl-L-Leucine methyl ester hydrobromide is a dipeptide condensation product targeting lymphocytes with cytotoxic potential. This compound selectively induces lymphocyte elimination while also triggering endolysosomal pathway stress. It is utilized in research applications focused on immune response modulation and cellular stress mechanisms. -
Polypeptide
YIGSR (Laminin Fragment 929-933) is a polypeptide that serves as an inhibitor of tumor growth and metastasis in leukemia cells. It exhibits specific binding to the 67kDa laminin receptor, influencing the expression of endothelial nitric oxide synthase (eNOS) in endothelial cells. This peptide is valuable for research focused on leukemia and related pathophysiological mechanisms. -
SPSB2-iNOS Inhibitor
SPSB2-iNOS inhibitory cyclic peptide-1 is a potent inhibitor targeting the interaction between SPSB2 and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity (KD) of 4.4 nM. This cyclic peptide demonstrates resistance to proteolytic degradation by pepsin, trypsin, and α-chymotrypsin, ensuring stability in biological environments. Additionally, it maintains stability in human plasma and oxidative conditions, making it a valuable tool for studying iNOS-related pathways in inflammation and other biological processes. -
Control Peptide
Tat-NR2Baa is a control peptide designed to evaluate the specificity of Tat-NR2B9c. This inactive variant features a double-point mutation in the COOH terminal tSXV motif, which prevents binding to the postsynaptic density protein PSD-95. While it retains structural similarity to Tat-NR2B9c, Tat-NR2Baa does not disrupt the PSD-95/NMDAR interaction. It serves as a valuable tool in studies investigating the roles of PSD-95 in NMDAR signaling pathways and related neurophysiological research. -
NO Synthase Activator
eNOS pT495 decoy peptide is a specific inhibitor designed to disrupt the phosphorylation at T495, thereby promoting eNOS uncoupling and preventing mitochondrial redistribution. This peptide serves as a valuable tool in the investigation of nitric oxide synthase activation, particularly in studies related to ventilator-induced lung injury and associated pathophysiological mechanisms. Its role in modulating eNOS activity makes it essential for exploring therapeutic approaches in respiratory and cardiovascular research. -
Antitumor Peptide
YIGSR-Lys(N3) is an antitumor peptide that targets cellular interactions with laminin I through the inhibition of the 67-kDa laminin-binding protein, effectively hindering the growth and metastasis of leukemic cells. Additionally, it modulates the shear-induced expression of endothelial nitric oxide synthase in laminin cells. This compound serves as a click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition and strain-promoted alkyne-azide cycloaddition reactions with alkyne-containing or DBCO/BCN-bearing molecules, respectively. Its versatile reactivity makes it valuable for research in both cancer biology and chemical biology applications. -
SPSB2-iNOS Inhibitor
SPSB2-iNOS inhibitory cyclic peptide-2 is a selective inhibitor of the interaction between SPSB2 and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity with a KD of 21 nM. This cyclic peptide is both reduction-resistant and oxidatively stable, making it suitable for various biological assays. Its ability to inhibit SPSB2-iNOS interactions positions it as a valuable tool in research focused on nitric oxide signaling and related pathophysiological processes. -
SPSB2-iNOS Inhibitor
SPSB2-iNOS inhibitory cyclic peptide-3 is a selective inhibitor targeting the interaction between SPSB2 and inducible nitric oxide synthase (iNOS). This compound binds to the SPSB2 site on iNOS with a dissociation constant (KD) of 7 nM. It demonstrates significant biological activity in modulating nitric oxide production and has potential applications in studies related to inflammation and oxidative stress. -
Antidepressant Peptide
Tat-SERT-15C is an antidepressant peptide that modulates the serotonin transporter (SERT) and nitric oxide synthase (nNOS) interaction. This peptide decreases the SERT-nNOS complex, leading to enhanced SERT expression. Tat-SERT-15C has demonstrated efficacy in reversing depression-like behaviors induced by chronic unpredictable mild stress, making it a valuable tool for research into the mechanisms of depression and potential therapeutic interventions. -
Thrombin Peptide
TP508 is a 23-amino acid nonproteolytic thrombin peptide that selectively targets the receptor-binding domain of thrombin. It activates endothelial nitric oxide synthase (eNOS) and promotes nitric oxide production in human endothelial cells, facilitating enhanced endothelial cell activation and stem cell recruitment. This molecule is of significant interest for applications in tissue revascularization and regenerative medicine research. -
FOXP3 Inhibitor
Peptide P60 is a potent FOXP3 inhibitor that disrupts the nuclear translocation of FOXP3, thereby decreasing its regulatory effects on NF-κB and NFAT signaling pathways. This action inhibits the immunosuppressive capabilities of regulatory T cells, facilitating the proliferation and activation of effector T cells. Experimental studies have shown that Peptide P60 can induce lymphoproliferative autoimmune syndrome in neonatal ICR mice and diminish the population of CD4+CD25+Foxp3+ T cells in the spleen. Additionally, it enhances the efficacy of peptide vaccines and recombinant adenovirus-based vaccines, making it valuable for research in tumor immunology, viral infections, and autoimmune conditions. -
Osteopontin-derived Peptide
SVVYGLR is an osteopontin-derived peptide that primarily promotes fibroblast differentiation into myofibroblast-like cells and enhances type III collagen production by cardiac fibroblasts. It effectively activates adhesion, migration, and tubule formation in endothelial cells, thereby facilitating angiogenesis and wound healing processes. Additionally, SVVYGLR supports the migration of dermal fibroblasts and keratinocytes, making it a valuable reagent for research in angiogenesis, dermal wounds, and bone regeneration studies. -
PSMA Targeting Peptide
PSMA Targeting Peptide (GRFLTGGTGRLLRIS) is designed to specifically bind to Prostate-Specific Membrane Antigen (PSMA) on prostate cancer cells. This peptide facilitates the targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs, enhancing the efficacy of RNA interference in therapeutic applications. The peptide can be modified by adding polyarginine sequences at the C-terminus, and when labeled with FITC through an aminohexanoic acid linker at the N-terminus, it allows for precise tracking of PSMA interactions in cellular contexts. -
Antioxidant Peptide
Antioxidant Peptide A is a short peptide featuring alternative aromatic or sulfur-containing amino acids, which facilitate its robust radical scavenging capabilities. This peptide exhibits significant antioxidant activity, demonstrating potential in mitigating oxidative stress within cancer cells. It serves as a valuable tool for research applications focused on oxidative damage and cancer biology. -
Anxiolytic Agent
δ-Sleep Inducing Peptide is a neuropeptide that functions as an anxiolytic agent. It exhibits antioxidant properties and plays a critical role in the modulation of sleep and anxiety-related behaviors. This compound is primarily used in research exploring neurobiology, sleep regulation, and mental health disorders. -
9-mer Peptide Probe
AE105 is a 9-mer peptide probe that specifically targets the urokinase-type plasminogen activator receptor (uPAR). It exhibits high-affinity binding to the uPA-binding cavity of uPAR, making it a valuable tool for investigating uPAR-related signaling pathways. This peptide probe is particularly useful in cancer research, aiding in the exploration of tumor progression and metastasis mechanisms. -
Bioactive Peptide
Thrombospondin (TSP-1)-derived CD36 binding motif is a bioactive hexapeptide that targets CD36 and angiostatin. This peptide disrupts cell adhesion and migration by interfering with the interaction between cells and the extracellular matrix. Additionally, it demonstrates the capability to inhibit platelet aggregation and exhibits anti-tumor properties, particularly against colon cancer. Its applications encompass studies of cell adhesion dynamics, platelet function, and potential therapeutic strategies in oncology. -
FKBPL Peptide
AD 01 is a 24-amino acid peptide derived from FKBPL (FK506-binding protein like), targeting the CD44 receptor to exert significant anti-angiogenic effects. By binding to CD44, AD 01 effectively inhibits tumor cell migration in a manner dependent on this receptor. This peptide is valuable for research applications focused on cancer biology, particularly in studies related to angiogenesis and tumor metastasis. -
GPR110 Agonist
GPR110 peptide agonist P12 is an agonist targeting the GPR110 receptor. This peptide significantly enhances the initial rate of G protein GTPγS binding stimulated by GPR110, effectively mimicking natural ligands. By inducing dissociation between the receptor's extracellular domain and its seven transmembrane domains, P12 exposes the β-strand-13/stalk region of the 7TM domain, facilitating G protein signaling activation. This compound is valuable for research into developmental disorders and cancers associated with GPR110 pathways. -
CD63-binding Peptide
CP05 is a CD63-binding peptide that specifically interacts with the exosome surface marker CD63. This interaction facilitates the anchoring of exosomes to target tissues, enhancing in vivo delivery of exosomal payloads. CP05 is useful in research applications focused on drug delivery, therapeutic targeting, and the study of exosome biology. -
Analogue of the Glycopeptide
Glycotriosyl glutamine is a synthetic analogue of Glycopeptide that targets glomerular structures in kidney cells. This compound has been shown to induce focal glomerulonephritis (FGN) in animal models, specifically resulting in the formation of myeloid bodies within podocyte epithelial cells. Its unique properties make it a valuable tool for investigating nephritogenic mechanisms and kidney disease pathology. -
CD36 Peptide
CD36 Peptide P (139-155), Cys conjugated targets the CD36 protein and serves as a crucial tool for studying its function. This Cys-conjugated peptide is effective in inhibiting the immunoadsorption of CD36 by the OKM5 antibody, making it valuable for research applications focused on immune responses and metabolic processes. The peptide can aid in the investigation of CD36-related pathways and its role in various biological contexts. -
Bioactive Peptide
Tumour-associated MUC1 epitope is a bioactive peptide targeting the MUC1 mucin, a type I transmembrane glycoprotein characterized by a highly glycosylated extracellular domain composed of repeated 20 amino acid units. This epitope is overexpressed on the surface of various human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma. Its frequent upregulation in cancer cells renders the MUC1 epitope a valuable target for the development of immunotherapeutic strategies, facilitating advancements in cancer treatment research. -
CD36 Peptide
CD36 Peptide P (93-110), Cys conjugated specifically targets CD36, a multifunctional receptor involved in cellular adhesion and lipid metabolism. This peptide has been shown to block the binding of CD36 to immobilized thrombospondin, thereby providing valuable insights into CD36-mediated pathways. Additionally, it partially inhibits collagen-induced platelet aggregation, making it useful for research applications related to cardiovascular function and cell signaling. -
Antigen Peptide Segment
[Gln144]-PLP (139-151) is an experimental antigen peptide segment designed to engage T-cell receptors (TCR) and activate T cells. This activation plays a crucial role in examining the immune response to both autoantigens and cross-reactive non-autoantigens. Its applications extend to the investigation of the underlying mechanisms involved in the regulation of autoimmune diseases, providing insights into potential therapeutic approaches. -
p32-targeting Peptide
LinTT1 peptide is a tumor-penetrating peptide that specifically targets the p32 (gC1qR) receptor. This peptide demonstrates enhanced cellular uptake in peritoneal carcinoma (PC) cells, facilitating mitochondrial entry and promoting targeted drug delivery. When conjugated with iron oxide nanoworms, LinTT1 forms a nanocarrier that significantly enhances tumor penetration and targeting in vivo. Additionally, when combined with the pro-apoptotic peptide [D(KLAKLAK)2], LinTT1-functionalized nanocarriers exhibit pronounced tumor suppression in mouse models of peritoneal cancer, highlighting its potential as an effective carrier in cancer research. -
VCAM1 Binding Peptide
VCAM1 Binding Peptide is designed to specifically bind to Vascular Cell Adhesion Molecule 1 (VCAM1). This peptide, with the sequence VHPKQHRGGSKGC, serves as a valuable tool for investigating VCAM1's role in cellular adhesion and inflammatory processes. It is commonly used in research applications focused on vascular biology, immunology, and disease models related to cardiovascular conditions. -
FAP-binding peptide
Rofapitide tetraxetan is a highly selective fibroblast activation protein (FAP)-binding peptide, exhibiting a mean IC50 of 2.7 nM for FAP binding. This compound demonstrates significant antitumor activity and can be effectively labeled with radionuclides for use in diagnostic imaging. Its specific targeting of FAP makes it a valuable tool for research applications in cancer diagnosis and therapy. -
FAP-Targeting Peptide
3BP-4089 is a potent fibroblast activation protein (FAP)-targeting peptide designed for theranostic applications. This peptide effectively facilitates the targeting of tumor microenvironments, allowing for enhanced imaging and therapeutic strategies. Coupling 3BP-4089 with radionuclides supports its utility in tumor diagnosis and advanced cancer research. -
GT1b Ligand
Tet1-Cys peptide is a specifically designed peptide that targets the GT1b ligand. It demonstrates the ability to bind to the neuronal ganglioside receptor GT1b, facilitating neuronal targeting in research applications. The inclusion of a cysteine residue in the Tet1-Cys peptide allows for efficient drug conjugation, making it a valuable tool for studies focused on drug delivery mechanisms and neuronal interactions. -
Neuron-Specific Ligand for GT1B
Tet1 peptide (HLNILSTLWKYR) is a neuron-specific ligand that selectively targets GT1B gangliosides. This peptide plays a crucial role in studies related to neuronal function and cell signaling. A commonly used variant includes a cysteine residue at the C-terminus (HLNILSTLWKYRC), facilitating peptide conjugation for drug delivery studies and enhancing research applications in neurobiology. -
cyclopentapeptide
Segetalin B is a cyclopentapeptide derived from Vaccaria segetalis, exhibiting estrogen-like activity. This compound promotes mineralization in ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and enhances levels of osteocalcin, BMP-2, alkaline phosphatase (ALP), and SIRT1 activity. Segetalin B holds potential for research into post-menopausal osteoporosis (PMOP) and related bone health studies. -
Tyrosinase Inhibitor
Decapeptide-12 is a selective inhibitor of tyrosinase, exhibiting a Kd of 61.1 μM and acting as a competitive inhibitor with an IC50 of 40 μM against mushroom tyrosinase. This decapeptide enhances the transcription of SIRT and effectively reduces melanin content in melanocytes. Decapeptide-12 is valuable for research involving melanogenesis, cellular senescence, and inflammation. -
Peptide Vaccine
Tertomotide hydrochloride is a peptide vaccine that targets the 16-amino acid sequence of human telomerase reverse transcriptase (hTERT). This compound exhibits neuroprotective properties and is primarily applied in research related to neurodegenerative conditions, including Alzheimer's disease. Its mechanism potentially aids in understanding disease pathways and developing therapeutic strategies. -
N-cadherin Agonist
N-Cadherin mimic peptide is an N-cadherin agonist that enhances N-cadherin homodimerization and β-catenin signaling. This peptide promotes early chondrogenesis and cartilage matrix production in mesenchymal stem cells (MSCs), making it a valuable tool for investigating MSC-based cartilage regeneration. Its role in promoting cell adhesion and differentiation underscores its potential in regenerative medicine research. -
Peptide Containing His-Ala-Val
HAV peptide (Ac-SHAVSS-NH2) specifically targets the E-cadherin signaling pathway and plays a crucial role in the regulation of intercellular junctions. This peptide is instrumental in various research applications focused on cellular adhesion, tissue integrity, and tumor biology. Its ability to modulate E-cadherin-mediated processes makes HAV peptide a valuable tool for investigating cellular interactions and their implications in disease models. -
Self-assembling peptides
CREKA peptide is a self-assembling peptide that selectively binds to fibrin, type IV collagen, and fibronectin. This peptide is utilized as a targeting ligand for modifying delivery carriers, facilitating the accumulation of therapeutic agents in tumor microenvironments and fibrotic tissues. By promoting drug internalization into specific target cells, such as cancer cells and activated hepatic stellate cells, CREKA peptide enhances targeted delivery efficiency, increasing local drug concentration while minimizing systemic side effects. -
Antioxidant Peptide
Tetrapeptide-1 is an antioxidant peptide that promotes the synthesis of extracellular matrix components, including collagen, elastin, and fibronectin. This activity makes Tetrapeptide-1 valuable in addressing the visible signs of skin aging, such as wrinkles and sagging. Its properties are widely utilized in cosmetic formulations aimed at improving skin texture and elasticity. -
Collagen Mimetic Peptide
Vezocolmitide is a collagen mimetic peptide designed to simulate collagen's structural properties. This compound primarily targets pathways involved in dry eye disease (DED), making it a valuable tool for research focused on ocular surface disorders. Its ability to mimic collagen may facilitate the study of tissue repair mechanisms and the development of potential therapeutic interventions for DED. -
Hair-generating Peptide
Myristoyl pentapeptide-4 is a bioactive peptide targeting hair follicles to promote hair growth. This molecule stimulates the anagen phase of hair development, making it beneficial in cosmetic applications aimed at enhancing hair density and health. Its activity supports research in both dermatology and cosmetic science, particularly in the formulation of hair restoration products. -
Cyclic Dipeptide
Cyclo(Ala-Hyp) is a cyclic dipeptide that targets collagen synthesis and hydroxyproline metabolism. This compound exhibits notable biological activity, demonstrating a significantly higher area under the curve (AUC0-6h) of 2.350 μg/mL·h compared to traditional collagen oligopeptides. Research applications for Cyclo(Ala-Hyp) include investigations into its protective effects on liver and kidney functions, as well as its potential benefits in skin care and joint health. -
Galectin-3 Binding Peptide
G3-C12 is a galectin-3 binding peptide with a Kd of 88 nM, designed to selectively target galectin-3. This compound demonstrates significant anticancer activity, making it a valuable tool in cancer research. G3-C12 can be utilized in studies investigating the role of galectin-3 in tumor progression and metastasis, as well as in the development of novel therapeutic strategies. -
GPVI Antagonist
Pep-10L peptide is a glycoprotein VI (GPVI) antagonist that exhibits inhibition with Ki values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. This peptide demonstrates significant anti-thrombotic effects, making it valuable for research in platelet function and thrombus formation. Pep-10L is useful in studies aimed at exploring GPVI signaling pathways and developing therapies for thrombotic diseases.
