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N-Acetyl Leu28, Leu31 neuropeptide Y (24–36)

Catalog No.: A62220
Neuropeptide
N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) is a selective agonist of the neuropeptide Y Y2 receptor. This compound has been shown to attenuate cardiac vagal activity in anesthetized rat models, making it a valuable tool for studying cardiac function and neuropeptide signaling. Its application in research can provide insights into cardiovascular regulation and potential therapeutic targets for heart-related conditions.
N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) 155709-24-3 Neuropeptide
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5mg
$105.00
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10mg
$170.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) is a selective agonist of the neuropeptide Y Y2 receptor. This compound has been shown to attenuate cardiac vagal activity in anesthetized rat models, making it a valuable tool for studying cardiac function and neuropeptide signaling. Its application in research can provide insights into cardiovascular regulation and potential therapeutic targets for heart-related conditions.
Product Information
Catalog NumA62220
FormulaC81H131N27O19
Molecular Weight1787.08
CAS Number155709-24-3
SequenceAc-Leu-Arg-His-Tyr-Leu-Asn-Leu-Leu-Thr-Arg-Gln-Arg-Tyr-NH2
Sequence shorteningAc-LRHYLNLLTRQRY-NH2
SMILES[C@@H](CC1=CC=C(O)C=C1)(NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CCCNC(=N)N)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N)=O)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O
SynonymsAc-[Leu28,31]-NPY (24-36)
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