Catalog No.
Product Name
Application
Product Information
Citations
-
FAP-binding peptide
Rofapitide tetraxetan is a highly selective fibroblast activation protein (FAP)-binding peptide, exhibiting a mean IC50 of 2.7 nM for FAP binding. This compound demonstrates significant antitumor activity and can be effectively labeled with radionuclides for use in diagnostic imaging. Its specific targeting of FAP makes it a valuable tool for research applications in cancer diagnosis and therapy. -
FAP-Targeting Peptide
3BP-4089 is a potent fibroblast activation protein (FAP)-targeting peptide designed for theranostic applications. This peptide effectively facilitates the targeting of tumor microenvironments, allowing for enhanced imaging and therapeutic strategies. Coupling 3BP-4089 with radionuclides supports its utility in tumor diagnosis and advanced cancer research. -
Tetrapeptide
H-Leu-Trp-Met-Arg-OH is a tetrapeptide that serves as a substrate for aminopeptidase-mediated hydrolysis studies. This compound allows researchers to investigate enzyme kinetics and activity, contributing to the understanding of peptide metabolism and regulation. Its applications extend to studies in proteomics and enzymology, facilitating advancements in biochemical research. -
CD13-binding Peptide
Aminopeptidase N Ligand (CD13) NGR peptide specifically targets CD13, serving as an effective carrier for facilitating intracellular transport. This polypeptide exhibits significant binding affinity to CD13, making it a valuable tool in cancer research. Its ability to mediate transport processes enhances its utility in studying tumor biology and therapeutic applications. -
Neuropeptide
Antho-rwamide I is a neuropeptide derived from the sea anemone Anthopleura elegantissima, known for its resistance to nonspecific aminopeptidases. This stability enhances its potential for sustained signaling after neuronal release, making it a valuable tool for studying neuropeptide interactions and mechanisms in neurobiology. Antho-rwamide I is applicable in research focused on neuronal signaling pathways and neuropeptide function. -
Substrate Peptide
Acetyltrialanine is a peptide substrate designed for Nα-acetyl alanine aminopeptidase, facilitating the investigation of enzyme activity and characteristics. This compound enables research into protein degradation and N-terminal regulation, making it a valuable tool for understanding proteolytic processes and related biological mechanisms. Its unique features allow for precise studies of enzyme kinetics and specificity in various biological contexts. -
Tripeptide
Suc-Ala-Ala-Pro-Leu-pNA is a tripeptidyl p-nitroanilide substrate that serves as a specific tool for studying the catalytic activity of acyl amidase-like leucine aminopeptidase in seminal plasma. This reagent enables the assessment of hydrolytic activity, making it valuable in investigations related to reproductive health, particularly in the context of azoospermia. Researchers can utilize Suc-Ala-Ala-Pro-Leu-pNA to explore the enzymatic mechanisms and potential therapeutic targets in male fertility disorders. -
Anti-angiogenic Peptide
Cartilostatin 1 is an anti-angiogenic peptide that inhibits the formation of new blood vessels. It exhibits significant potential in modulating angiogenesis, making it a valuable tool for research in cancer biology, wound healing, and other conditions where vascular growth regulation is crucial. Its biological activity may be leveraged in studies exploring therapeutic strategies for diseases characterized by aberrant angiogenesis. -
Apolipoprotein Peptide
APL180 is an apolipoprotein A-I mimic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL). This compound is valuable in research focused on cardiovascular diseases, leveraging its properties to study HDL's role in inflammation and lipid metabolism. -
Peptide
Dansyl-Ala-Arg is a synthetic peptide that serves as a fluorescent probe targeting various biochemical processes. It is commonly utilized in studies involving peptide interactions, protein conformation, and cellular imaging. Its unique fluorescent properties make it an effective tool for monitoring biological events in live cells and in vitro assays. -
Depsipeptide Substrate for DD-carboxypeptidases
Ac-Lys(Ac)-D-Ala-D-Lactic acid serves as a depsipeptide substrate specifically targeting DD-carboxypeptidases, which are penicillin-sensitive D-alanine carboxypeptidases. This compound is utilized in research to investigate the enzymatic activity and functionality of these peptidases, playing a crucial role in bacterial cell wall synthesis and maintenance. Its application in enzymatic studies provides insights into antibiotic action mechanisms and potential resistance pathways. -
Peptide Toxin
Poneratoxin is a peptide toxin that acts as a modulator of voltage-gated sodium channels (NaV), specifically NaV1.6 and NaV1.7, with EC50 values of 97 nM and 2.3 µM, respectively. It lowers the voltage threshold for channel activation and inhibits their inactivation, thereby enhancing neuronal excitability. This activity is relevant in studies of pain signal transmission and neuropathic pain research, making Poneratoxin a valuable tool in neurobiology and pharmacological investigations. -
Galectin-3 Binding Peptide
G3-C12 is a galectin-3 binding peptide with a Kd of 88 nM, designed to selectively target galectin-3. This compound demonstrates significant anticancer activity, making it a valuable tool in cancer research. G3-C12 can be utilized in studies investigating the role of galectin-3 in tumor progression and metastasis, as well as in the development of novel therapeutic strategies. -
GPVI Antagonist
Pep-10L peptide is a glycoprotein VI (GPVI) antagonist that exhibits inhibition with Ki values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. This peptide demonstrates significant anti-thrombotic effects, making it valuable for research in platelet function and thrombus formation. Pep-10L is useful in studies aimed at exploring GPVI signaling pathways and developing therapies for thrombotic diseases. -
GPC3 Targeting Peptide
GPC3 Targeting Peptide 1 is a synthetic peptide that selectively binds to glypican-3 (GPC3) with a dissociation constant (Kd) of 0.23 nM. This high-affinity interaction makes it a valuable tool for GPC3-related research, including studies on cancer biology, particularly in liver cancer, and potential therapeutic applications targeting GPC3-expressing tumors. The peptide's specificity for GPC3 facilitates the exploration of mechanisms underlying tumorigenesis and enables the development of targeted drug delivery systems. -
Bioactive Peptide
IGRP(206-214) is a bioactive peptide derived from the residues 206-214 of the murine islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP). This peptide specifically targets T cells associated with proinsulin and IGRP, playing a pivotal role in the induction of diabetes in non-obese diabetic (NOD) mice models. IGRP(206-214) is valuable for research applications focused on autoimmune diabetes and T cell-mediated responses. -
KRAS G12V Peptide
KRAS G12V Peptide is a synthetic peptide derived from the Kirsten rat sarcoma virus (KRAS) gene featuring the oncogenic G12V mutation. This peptide is known to stimulate immune responses, including the secretion of IFN-γ and enhanced cytotoxic activity. KRAS G12V Peptide serves as a valuable tool for investigating immune responses to KRAS G12V-mutant tumors, facilitating research in cancer immunotherapy and tumor biology. -
Peptide Segment
MSP-1 (20-39) is a peptide segment that stimulates the production of interferon-gamma (IFN-γ). This functionality positions MSP-1 (20-39) as a potential candidate for malaria vaccine development. It serves as a valuable tool for research in malaria and immunology, enabling studies into immune responses and disease mitigation strategies. -
IFNAR
IFN-α Receptor Recognition Peptide 1 specifically targets the IFN-α receptor (IFNAR), facilitating the interaction between interferon and its receptor. This peptide plays a crucial role in modulating immune responses, making it valuable for research in immunology and virology. It can be utilized to study signaling pathways associated with interferon signaling, as well as in the development of therapeutic strategies against viral infections and autoimmune diseases. -
Peptide
MBP (83-99) is a peptide that targets the immunodominant epitope of myelin basic protein (MBP). This peptide is essential for the study of T cell responses, particularly in the context of multiple sclerosis research, as it stimulates the proliferation of T cells and the secretion of interferon-gamma (IFN-γ). It serves as a valuable tool for investigating autoimmune mechanisms and T cell immunology. -
KRAS G12C Peptide
KRAS G12C Peptide specifically targets the KRAS G12C oncogenic mutation, derived from the Kirsten rat sarcoma virus (KRAS) gene. This peptide elicits immune responses, including the secretion of IFN-γ and enhanced cytotoxicity, making it a valuable tool for investigating the immune dynamics against KRAS G12C-mutant tumors. It is particularly applicable in cancer research focused on developing immunotherapies and understanding tumor-immune interactions. -
Bioactive Peptide
IRAK-4 Peptide substrate (IRAK-1 residues 360-380) is a bioactive peptide specifically designed to serve as a substrate for Interleukin-1 Receptor-Associated Kinase 4 (IRAK-4). This peptide facilitates the study of IRAK-4's role in signal transduction pathways associated with inflammatory responses. It is suitable for applications in cellular signaling research, particularly in the context of immune system studies and cytokine signaling. -
Peptide Substrate
Cbz-Lys-Arg-pNA is a peptide substrate designed for enzyme assays, featuring p-nitroaniline (pNA) as a chromogenic reporter group. This compound is extensively utilized in the characterization of serine proteases such as thrombin, plasmin, factor Xa, and kallikrein. Its ability to generate a measurable color change upon enzymatic cleavage makes it a valuable tool in biochemical research and diagnostic applications. -
Bioactive Peptide
OVA-T4 Peptide (SIITFEKL) is a bioactive peptide variant of the ovalbumin epitope (OVA (257-264)), known for its binding to H-2Kb MHC class I molecules. This peptide exhibits comparable binding strength to H-2Kb but demonstrates significantly reduced affinity for the OT-I TCR. OVA-T4 Peptide is useful in research focused on T cell responses and MHC-TCR interactions, making it valuable for the study of immunological mechanisms and peptide-MHC complex dynamics. -
Peptide
OVA peptide is a class I (Kb)-restricted peptide epitope derived from ovalbumin, associated with the major histocompatibility complex (MHC) molecule H-2Kb in mice. This peptide plays a crucial role in immune response studies, particularly in allergy research, where it serves as a model antigen. Its ability to elicit specific T cell responses makes OVA peptide a valuable tool for understanding immune mechanisms and developing therapeutic strategies in allergy and immunology. -
Polypeptide
Gp100 (25-33), human is a polypeptide fragment comprising amino acids 25-33 of the human melanoma antigen. This 9-amino acid epitope is restricted by MHC class I H-2Db and elicits a specific T cell response due to its immunogenic properties. Gp100 (25-33), human is valuable for cancer research, particularly in studies focused on melanoma and T cell-mediated immune responses. -
Ras Inhibitor
Ras Inhibitory Peptide (VPPPVPPRRR) is a specific inhibitor of Ras proteins, known for its antitumor activity. This peptide disrupts Ras signaling pathways, which are critical for cell growth and proliferation, making it a valuable tool in cancer research. Its ability to modulate Ras activity allows for the investigation of therapeutic strategies targeting oncogenic Ras mutations. -
Peptide
Rac1 Inhibitor W56 is a peptide that targets Rac1 by mimicking residues 45-60 of the protein. This inhibitor effectively disrupts the interaction between Rac1 and guanine nucleotide exchange factors such as TrioN, GEF-H1, and Tiam. Rac1 Inhibitor W56 is valuable for research applications focused on studying the role of Rac1 in cellular processes, including migration, invasion, and cytoskeletal dynamics. -
Immune Potentiator
KRAS G13D peptide, 25 mer, is an immune potentiator derived from a KRAS oncogene mutation. This peptide plays a crucial role in stimulating immune responses and can be utilized in the development of KRAS-targeted vaccines. Its application in cancer immunotherapy research makes it a valuable tool for studying the interactions between mutated KRAS and immune system activation. -
Tool Peptide
Myr-Arf1(2–17) is a sarcosinated peptide designed to mimic the localization and functionality of Arf1 protein at the cell membrane. This tool peptide serves as an important research reagent for investigating the desensitization mechanisms of the luteinizing hormone/chorionic gonadotropin receptor (LH/CGR). Its utility in studying cellular signaling pathways provides valuable insights into receptor dynamics and function. -
Relaxin Peptide
Relaxin H3 (human) is a relaxin peptide that primarily targets the RXFP1 receptor. It exhibits potent antifibrotic properties, making it valuable for research focused on fibrosis and tissue remodeling. This compound is useful in studying the pathways involved in extracellular matrix regulation and may have implications for therapeutic strategies in fibrotic diseases. -
Neuropeptide
Cortistatin 14 is a neuropeptide that primarily targets somatostatin receptors (SSTRs) and the ghrelin receptor. This compound exhibits neuronal depressant and sleep-modulating properties, making it vital for studies related to sleep physiology and neural signaling. Additionally, its presence alongside GABA in the cortex and hippocampus highlights its role in modulating neurotransmission and potential applications in researching sleep disorders and neurodegenerative conditions. -
Somatostatin Neuropeptide
Cortistatin-17 (human) is a somatostatin neuropeptide that modulates neuroendocrine signaling through its interaction with somatostatin receptors. Its biological activities include the regulation of endocrine and exocrine functions, as well as potential anti-inflammatory effects. This peptide is valuable for research applications related to cancer, inflammation, autoimmunity, fibrosis, and pain. -
Somatostatin Neuropeptide
Cortistatin-29 (human) is a somatostatin neuropeptide that modulates a variety of biological functions by interacting with somatostatin receptors. This compound exhibits key biological activities, including anti-inflammatory effects and regulation of pain pathways, making it relevant for research applications in cancer, inflammation, autoimmunity, fibrosis, and pain management. Its unique biological profile allows for exploration of potential therapeutic strategies targeting these conditions. -
Neuroavtive Peptide
[Tyr11]-Somatostatin is a neuroactive peptide that modulates various physiological processes by targeting somatostatin receptors. This compound is essential for studying the role of neuroactive substances in retinal physiology and their implications in various neurobiological research applications. Its use in proteomics research contributes to a deeper understanding of neuronal signaling pathways and potential therapeutic targets. -
Neuropeptide
Cortistatin-29 is a rat neuropeptide that targets somatostatin receptors (SSTRs) with high affinity, exhibiting IC50 values of 2.8 nM for SSTR1, 7.1 nM for SSTR2, 0.2 nM for SSTR3, 3.0 nM for SSTR4, and 13.7 nM for SSTR5. This compound is known to alleviate neuropathic pain and demonstrates anti-fibrotic properties. Its diverse biological activities make it a valuable tool for research in neurobiology and fibrosis-related studies. -
Tetradecapeptide
[D-Trp8] Somatostatin-14 is a tetradecapeptide analog of somatostatin that exhibits enhanced potency compared to its native counterpart. This compound primarily targets somatostatin receptors, influencing various physiological processes including hormonal secretion and cell proliferation. It is utilized in research applications focusing on neuroendocrine regulation and the therapeutic potential of somatostatin analogs in treating conditions such as acromegaly and neuroendocrine tumors. -
Urotensin II Anague
Urotensin II-related peptide is an analog of human urotensin II, exhibiting high affinity for the urotensin II receptor (UT). This peptide plays a significant role in cardiovascular regulation and may influence vascular smooth muscle contraction. It is commonly utilized in research focused on cardiovascular diseases, neurobiology, and the study of peptide receptor interactions. -
urotensin-II Receptor Antagonist Peptide
Urantide is a selective and competitive antagonist of the urotensin-II (UT) receptor, exhibiting a pKB of 8.3. This peptide effectively inhibits human urotensin-II (hU-II)-induced contractions in rat thoracic aorta ex vivo. Urantide is valuable for investigating the (patho)physiological roles of hU-II in the mammalian cardiovascular system, making it an important tool for related research applications. -
Cyclic Peptide
Urotensin II, teleost fish, is a cyclic peptide that plays a significant role in regulating cardiovascular and endocrine functions in teleost species. This peptide is involved in vasoconstriction and modulation of blood pressure, making it a valuable tool for research into fish physiology and neuroendocrine signaling. Its unique biological activities provide insights into the evolutionary adaptations of stress responses in aquatic environments. -
Antidiuretic Peptide
F992 is an analogue of vasopressin, also known as antidiuretic hormone, targeting the antidiuretic peptide pathways. This compound exhibits significant activity in modulating water reabsorption in the kidneys and has applications in research focused on fluid balance, blood pressure regulation, and related endocrine functions. F992 serves as a valuable tool for investigating the physiological and pathological roles of antidiuretic peptides in various biological systems. -
HLA-A1-restricted T-cell Epitope
AIM2-derived decapeptide is an HLA-A1-restricted T-cell epitope that targets the AIM2 pathway. This peptide plays a significant role in immune response modulation and has potential applications in the study of melanoma. Researchers can utilize this decapeptide to investigate T-cell responses and the mechanisms underlying tumor immunity. -
BCL6 Inhibitor
SMRT peptide is a BCL6 inhibitor that functions by binding to the BTB domain of BCL6, thereby enhancing its transcriptional repression activity. This compound serves as a valuable tool for studying protein-protein interactions related to BCL6 function in various biological processes. Research applications include investigations into the role of BCL6 in cancer and other diseases where transcriptional regulation is critical. -
Bioactive Peptide
CFP10 (71–85) is a bioactive peptide that stimulates the production of interferon-gamma (IFN-γ) and enhances cytotoxic T lymphocyte (CTL) activity in both CD4+ and CD8+ T cells. It is particularly effective in individuals expressing various MHC class II and class I molecules. This peptide is valuable for research applications focused on immune response modulation and T cell activation. -
CD47/SIRPα blocking peptide
Pep-20 is a CD47/SIRPα blocking peptide that inhibits the interaction between CD47 and SIRPα, demonstrating KD values of 2.91 μM for human CD47 and 3.63 μM for mouse CD47. With IC50 values of 24.56 μM and 12.03 μM, respectively, for blocking these interactions, Pep-20 exhibits significant anti-tumor activity. This peptide is useful in research applications focused on immune evasion in cancer therapies and interactions within the tumor microenvironment. -
Thrombospondin-1-Derived Peptide
Thrombospondin-1 (1016-1021) is a peptide derived from Thrombospondin-1 that lacks CD47-binding activity. This truncated peptide is useful for studying the regulatory roles of Thrombospondin-1 in cellular processes such as angiogenesis and cell adhesion. Its applications in research include investigations into the modulation of immune responses and the exploration of potential therapeutic targets in various diseases. -
Muramil-dipeptide Analogue
Glucosaminylmuramyl dipeptide (GMDP) is a synthetic analogue of muramil-dipeptide, functioning primarily as an inhibitor of 5'-nucleotidase activity. This compound exhibits significant antitumor effects and is valuable in the study of sepsis. Researchers can utilize GMDP to investigate immune responses and therapeutic interventions in oncological and inflammatory contexts. -
Pentapeptide
Angiotensin I/II (4-8) is a pentapeptide that corresponds to the C-terminal sequence of Angiotensin II. This compound has significant implications in cardiovascular research, specifically in studies involving blood pressure regulation and the renin-angiotensin system. Its biological activity includes the modulation of vasoconstriction and electrolyte balance, making it a valuable reagent for investigating related physiological and pathological processes. -
Immunomodulatory Octapeptide
Thymoctonan is an immunomodulatory octapeptide, also known as thymic humoral factor γ2. It plays a crucial role in modulating immune responses and has applications in research related to immunotherapy and autoimmune disorders. Thymoctonan exhibits a short half-life of less than 6 minutes at 37 °C in human, rat, and mouse blood, which should be considered when designing experiments. -
pGC-B Activator
C-Type Natriuretic Peptide (1-53), derived from porcine, rat, and mouse sources, acts as a specific activator of particulate guanylate cyclase B (pGC-B), a receptor prevalent in endothelial cells, kidneys, and cardiac tissues. This peptide is known to induce significant anti-fibrotic responses in human cardiac and renal fibroblasts by promoting the synthesis of the secondary messenger cGMP. It is valuable for research focusing on cardiovascular and renal pathophysiology, offering insights into therapeutic strategies for fibrotic diseases.
