Catalog No.
Product Name
Application
Product Information
Citations
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GPC3 Targeting Peptide
GPC3 Targeting Peptide 1 is a synthetic peptide that selectively binds to glypican-3 (GPC3) with a dissociation constant (Kd) of 0.23 nM. This high-affinity interaction makes it a valuable tool for GPC3-related research, including studies on cancer biology, particularly in liver cancer, and potential therapeutic applications targeting GPC3-expressing tumors. The peptide's specificity for GPC3 facilitates the exploration of mechanisms underlying tumorigenesis and enables the development of targeted drug delivery systems. -
Bioactive Peptide
IGRP(206-214) is a bioactive peptide derived from the residues 206-214 of the murine islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP). This peptide specifically targets T cells associated with proinsulin and IGRP, playing a pivotal role in the induction of diabetes in non-obese diabetic (NOD) mice models. IGRP(206-214) is valuable for research applications focused on autoimmune diabetes and T cell-mediated responses. -
KRAS G12V Peptide
KRAS G12V Peptide is a synthetic peptide derived from the Kirsten rat sarcoma virus (KRAS) gene featuring the oncogenic G12V mutation. This peptide is known to stimulate immune responses, including the secretion of IFN-γ and enhanced cytotoxic activity. KRAS G12V Peptide serves as a valuable tool for investigating immune responses to KRAS G12V-mutant tumors, facilitating research in cancer immunotherapy and tumor biology. -
Peptide Segment
MSP-1 (20-39) is a peptide segment that stimulates the production of interferon-gamma (IFN-γ). This functionality positions MSP-1 (20-39) as a potential candidate for malaria vaccine development. It serves as a valuable tool for research in malaria and immunology, enabling studies into immune responses and disease mitigation strategies. -
IFNAR
IFN-α Receptor Recognition Peptide 1 specifically targets the IFN-α receptor (IFNAR), facilitating the interaction between interferon and its receptor. This peptide plays a crucial role in modulating immune responses, making it valuable for research in immunology and virology. It can be utilized to study signaling pathways associated with interferon signaling, as well as in the development of therapeutic strategies against viral infections and autoimmune diseases. -
Peptide
MBP (83-99) is a peptide that targets the immunodominant epitope of myelin basic protein (MBP). This peptide is essential for the study of T cell responses, particularly in the context of multiple sclerosis research, as it stimulates the proliferation of T cells and the secretion of interferon-gamma (IFN-γ). It serves as a valuable tool for investigating autoimmune mechanisms and T cell immunology. -
KRAS G12C Peptide
KRAS G12C Peptide specifically targets the KRAS G12C oncogenic mutation, derived from the Kirsten rat sarcoma virus (KRAS) gene. This peptide elicits immune responses, including the secretion of IFN-γ and enhanced cytotoxicity, making it a valuable tool for investigating the immune dynamics against KRAS G12C-mutant tumors. It is particularly applicable in cancer research focused on developing immunotherapies and understanding tumor-immune interactions. -
Bioactive Peptide
IRAK-4 Peptide substrate (IRAK-1 residues 360-380) is a bioactive peptide specifically designed to serve as a substrate for Interleukin-1 Receptor-Associated Kinase 4 (IRAK-4). This peptide facilitates the study of IRAK-4's role in signal transduction pathways associated with inflammatory responses. It is suitable for applications in cellular signaling research, particularly in the context of immune system studies and cytokine signaling. -
Peptide Substrate
Cbz-Lys-Arg-pNA is a peptide substrate designed for enzyme assays, featuring p-nitroaniline (pNA) as a chromogenic reporter group. This compound is extensively utilized in the characterization of serine proteases such as thrombin, plasmin, factor Xa, and kallikrein. Its ability to generate a measurable color change upon enzymatic cleavage makes it a valuable tool in biochemical research and diagnostic applications. -
Bioactive Peptide
OVA-T4 Peptide (SIITFEKL) is a bioactive peptide variant of the ovalbumin epitope (OVA (257-264)), known for its binding to H-2Kb MHC class I molecules. This peptide exhibits comparable binding strength to H-2Kb but demonstrates significantly reduced affinity for the OT-I TCR. OVA-T4 Peptide is useful in research focused on T cell responses and MHC-TCR interactions, making it valuable for the study of immunological mechanisms and peptide-MHC complex dynamics. -
Peptide
OVA peptide is a class I (Kb)-restricted peptide epitope derived from ovalbumin, associated with the major histocompatibility complex (MHC) molecule H-2Kb in mice. This peptide plays a crucial role in immune response studies, particularly in allergy research, where it serves as a model antigen. Its ability to elicit specific T cell responses makes OVA peptide a valuable tool for understanding immune mechanisms and developing therapeutic strategies in allergy and immunology. -
Polypeptide
Gp100 (25-33), human is a polypeptide fragment comprising amino acids 25-33 of the human melanoma antigen. This 9-amino acid epitope is restricted by MHC class I H-2Db and elicits a specific T cell response due to its immunogenic properties. Gp100 (25-33), human is valuable for cancer research, particularly in studies focused on melanoma and T cell-mediated immune responses. -
Ras Inhibitor
Ras Inhibitory Peptide (VPPPVPPRRR) is a specific inhibitor of Ras proteins, known for its antitumor activity. This peptide disrupts Ras signaling pathways, which are critical for cell growth and proliferation, making it a valuable tool in cancer research. Its ability to modulate Ras activity allows for the investigation of therapeutic strategies targeting oncogenic Ras mutations. -
Peptide
Rac1 Inhibitor W56 is a peptide that targets Rac1 by mimicking residues 45-60 of the protein. This inhibitor effectively disrupts the interaction between Rac1 and guanine nucleotide exchange factors such as TrioN, GEF-H1, and Tiam. Rac1 Inhibitor W56 is valuable for research applications focused on studying the role of Rac1 in cellular processes, including migration, invasion, and cytoskeletal dynamics. -
Immune Potentiator
KRAS G13D peptide, 25 mer, is an immune potentiator derived from a KRAS oncogene mutation. This peptide plays a crucial role in stimulating immune responses and can be utilized in the development of KRAS-targeted vaccines. Its application in cancer immunotherapy research makes it a valuable tool for studying the interactions between mutated KRAS and immune system activation. -
Tool Peptide
Myr-Arf1(2–17) is a sarcosinated peptide designed to mimic the localization and functionality of Arf1 protein at the cell membrane. This tool peptide serves as an important research reagent for investigating the desensitization mechanisms of the luteinizing hormone/chorionic gonadotropin receptor (LH/CGR). Its utility in studying cellular signaling pathways provides valuable insights into receptor dynamics and function. -
Relaxin Peptide
Relaxin H3 (human) is a relaxin peptide that primarily targets the RXFP1 receptor. It exhibits potent antifibrotic properties, making it valuable for research focused on fibrosis and tissue remodeling. This compound is useful in studying the pathways involved in extracellular matrix regulation and may have implications for therapeutic strategies in fibrotic diseases. -
Neuropeptide
Cortistatin 14 is a neuropeptide that primarily targets somatostatin receptors (SSTRs) and the ghrelin receptor. This compound exhibits neuronal depressant and sleep-modulating properties, making it vital for studies related to sleep physiology and neural signaling. Additionally, its presence alongside GABA in the cortex and hippocampus highlights its role in modulating neurotransmission and potential applications in researching sleep disorders and neurodegenerative conditions. -
Somatostatin Neuropeptide
Cortistatin-17 (human) is a somatostatin neuropeptide that modulates neuroendocrine signaling through its interaction with somatostatin receptors. Its biological activities include the regulation of endocrine and exocrine functions, as well as potential anti-inflammatory effects. This peptide is valuable for research applications related to cancer, inflammation, autoimmunity, fibrosis, and pain. -
Somatostatin Neuropeptide
Cortistatin-29 (human) is a somatostatin neuropeptide that modulates a variety of biological functions by interacting with somatostatin receptors. This compound exhibits key biological activities, including anti-inflammatory effects and regulation of pain pathways, making it relevant for research applications in cancer, inflammation, autoimmunity, fibrosis, and pain management. Its unique biological profile allows for exploration of potential therapeutic strategies targeting these conditions. -
Neuroavtive Peptide
[Tyr11]-Somatostatin is a neuroactive peptide that modulates various physiological processes by targeting somatostatin receptors. This compound is essential for studying the role of neuroactive substances in retinal physiology and their implications in various neurobiological research applications. Its use in proteomics research contributes to a deeper understanding of neuronal signaling pathways and potential therapeutic targets. -
Neuropeptide
Cortistatin-29 is a rat neuropeptide that targets somatostatin receptors (SSTRs) with high affinity, exhibiting IC50 values of 2.8 nM for SSTR1, 7.1 nM for SSTR2, 0.2 nM for SSTR3, 3.0 nM for SSTR4, and 13.7 nM for SSTR5. This compound is known to alleviate neuropathic pain and demonstrates anti-fibrotic properties. Its diverse biological activities make it a valuable tool for research in neurobiology and fibrosis-related studies. -
Tetradecapeptide
[D-Trp8] Somatostatin-14 is a tetradecapeptide analog of somatostatin that exhibits enhanced potency compared to its native counterpart. This compound primarily targets somatostatin receptors, influencing various physiological processes including hormonal secretion and cell proliferation. It is utilized in research applications focusing on neuroendocrine regulation and the therapeutic potential of somatostatin analogs in treating conditions such as acromegaly and neuroendocrine tumors. -
Urotensin II Anague
Urotensin II-related peptide is an analog of human urotensin II, exhibiting high affinity for the urotensin II receptor (UT). This peptide plays a significant role in cardiovascular regulation and may influence vascular smooth muscle contraction. It is commonly utilized in research focused on cardiovascular diseases, neurobiology, and the study of peptide receptor interactions. -
urotensin-II Receptor Antagonist Peptide
Urantide is a selective and competitive antagonist of the urotensin-II (UT) receptor, exhibiting a pKB of 8.3. This peptide effectively inhibits human urotensin-II (hU-II)-induced contractions in rat thoracic aorta ex vivo. Urantide is valuable for investigating the (patho)physiological roles of hU-II in the mammalian cardiovascular system, making it an important tool for related research applications. -
Cyclic Peptide
Urotensin II, teleost fish, is a cyclic peptide that plays a significant role in regulating cardiovascular and endocrine functions in teleost species. This peptide is involved in vasoconstriction and modulation of blood pressure, making it a valuable tool for research into fish physiology and neuroendocrine signaling. Its unique biological activities provide insights into the evolutionary adaptations of stress responses in aquatic environments. -
Antidiuretic Peptide
F992 is an analogue of vasopressin, also known as antidiuretic hormone, targeting the antidiuretic peptide pathways. This compound exhibits significant activity in modulating water reabsorption in the kidneys and has applications in research focused on fluid balance, blood pressure regulation, and related endocrine functions. F992 serves as a valuable tool for investigating the physiological and pathological roles of antidiuretic peptides in various biological systems. -
HLA-A1-restricted T-cell Epitope
AIM2-derived decapeptide is an HLA-A1-restricted T-cell epitope that targets the AIM2 pathway. This peptide plays a significant role in immune response modulation and has potential applications in the study of melanoma. Researchers can utilize this decapeptide to investigate T-cell responses and the mechanisms underlying tumor immunity. -
BCL6 Inhibitor
SMRT peptide is a BCL6 inhibitor that functions by binding to the BTB domain of BCL6, thereby enhancing its transcriptional repression activity. This compound serves as a valuable tool for studying protein-protein interactions related to BCL6 function in various biological processes. Research applications include investigations into the role of BCL6 in cancer and other diseases where transcriptional regulation is critical. -
Bioactive Peptide
CFP10 (71–85) is a bioactive peptide that stimulates the production of interferon-gamma (IFN-γ) and enhances cytotoxic T lymphocyte (CTL) activity in both CD4+ and CD8+ T cells. It is particularly effective in individuals expressing various MHC class II and class I molecules. This peptide is valuable for research applications focused on immune response modulation and T cell activation. -
CD47/SIRPα blocking peptide
Pep-20 is a CD47/SIRPα blocking peptide that inhibits the interaction between CD47 and SIRPα, demonstrating KD values of 2.91 μM for human CD47 and 3.63 μM for mouse CD47. With IC50 values of 24.56 μM and 12.03 μM, respectively, for blocking these interactions, Pep-20 exhibits significant anti-tumor activity. This peptide is useful in research applications focused on immune evasion in cancer therapies and interactions within the tumor microenvironment. -
Thrombospondin-1-Derived Peptide
Thrombospondin-1 (1016-1021) is a peptide derived from Thrombospondin-1 that lacks CD47-binding activity. This truncated peptide is useful for studying the regulatory roles of Thrombospondin-1 in cellular processes such as angiogenesis and cell adhesion. Its applications in research include investigations into the modulation of immune responses and the exploration of potential therapeutic targets in various diseases. -
Muramil-dipeptide Analogue
Glucosaminylmuramyl dipeptide (GMDP) is a synthetic analogue of muramil-dipeptide, functioning primarily as an inhibitor of 5'-nucleotidase activity. This compound exhibits significant antitumor effects and is valuable in the study of sepsis. Researchers can utilize GMDP to investigate immune responses and therapeutic interventions in oncological and inflammatory contexts. -
Prebiotic Peptide
H-D-Trp-OH, the D-isomer of tryptophan, serves as a prebiotic peptide that enhances intestinal microbial diversity. This compound has demonstrated the ability to mitigate the adverse effects of allergic airway inflammation on gut microbial populations. Its unique properties make it a valuable tool for researching intestinal health and microbiome interactions. -
Tetradecapeptide
Mastoparan is a tetradecapeptide derived from wasp venom that primarily targets and stimulates the release of prolactin from cultured rat anterior pituitary cells. This compound is widely used in research to investigate endocrine signaling pathways and the physiological roles of prolactin. Additionally, Mastoparan may serve as a valuable tool for studying neuroendocrine processes and the regulation of hormone secretion. -
Bacterial Peptide Lipid Substance
D-Allothreonine is the D stereoisomer of allothreonine, targeting bacterial peptide lipid substances. This compound can be specifically oxidized by D-amino acid oxidase, illustrating its unique reactivity compared to its L counterpart. D-Allothreonine plays a crucial role as a component of bacterial polysaccharides, making it valuable for studies on bacterial pathogenicity, antigenic variation, and mechanisms of drug resistance. Its specific biochemical interactions and applications in microbiological research highlight its significance in advancing understanding of bacterial behavior and treatment strategies. -
Polypeptide
Systemin is an 18-amino acid polypeptide that functions as a significant inducer of defensive gene expression in plants. Isolated from tomato leaves, Systemin activates the expression of more than 15 genes involved in plant defense mechanisms. This compound is valuable for research applications focused on plant stress responses, signaling pathways, and the study of plant-pathogen interactions. -
dipeptide
Lysylglutamic acid is a dipeptide comprising the amino acids lysine and glutamic acid. It interacts with the membrane transporter PEPT1, exhibiting a Ki value of 1.3 mM. This compound is utilized in research focused on peptide transport and metabolism, providing insights into cellular uptake mechanisms of dipeptides. Its biochemical properties make it valuable for studies in nutrition, pharmacology, and drug delivery systems. -
Bombesin-Like Peptide
Alytesin, a bombesin-like peptide derived from the skin of Alytes obstetricans, primarily targets neurokinin receptors. It is known to reduce gastric acid secretion and induce hypertension. Additionally, Alytesin demonstrates short-term anorexigenic effects in neonatal chicks, making it a valuable tool for research in gastrointestinal physiology and neuroendocrine regulation. -
Polypeptide
Glutathionylspermidine is a polypeptide that functions as a metabolite in Escherichia coli. This compound has been implicated in cellular stress response mechanisms, showcasing antioxidant properties that protect against oxidative damage. Its role in bacterial physiology makes it a valuable tool for studying bacterial metabolism and stress adaptation in various research applications. -
Neuropeptide
Allatotropin is a 13-amino acid neuropeptide that primarily activates the inositol 1,4,5-trisphosphate (IP3) signaling pathway. It plays a crucial role in the biosynthesis of juvenile hormone (JH) in the insect Manduca sexta, making it valuable for studies in insect physiology and hormonal regulation. This compound is suitable for research applications exploring neuropeptide signaling and developmental processes in arthropods. -
Antihypertensive Peptide
Salusin-β is an endogenous bioactive peptide that primarily functions as an antihypertensive agent. It exhibits significant hemodynamic and mitogenic activities, stimulating the proliferation of vascular smooth muscle cells and fibroblasts, which contributes to notable decreases in blood pressure and heart rate. Additionally, Salusin-β promotes the release of arginine vasopressin from the pituitary gland in animal models, highlighting its potential applications in cardiovascular disease research and the study of vascular dynamics. -
Thymosin β4-like Peptide
Thymosin β10Arg is a thymosin β4-like peptide modified by the addition of arginine after lysine-38. This structural modification enhances its biological activity, influencing cytoskeletal dynamics and cellular behavior. Thymosin β10Arg is applicable in research involving cell migration, wound healing, and tissue regeneration studies. -
Glycopeptide
7,8,7’,8’-Tetradehydroastaxanthin is a glycopeptide derived from the carotenoid protein of the red sea star (Asterias rubens). This compound exhibits antioxidant properties and plays a significant role in photoprotection. Its unique chemical structure and biological activity make it a valuable tool in studies related to marine biology and nutritional science. -
Peptide
Cyclic somatostatin acetate is a neuropeptide that primarily targets growth hormone release inhibition. It plays a critical role in cardiovascular research by modulating the contractile response of ventricular cardiomyocytes, with an IC50 value of 13 nM against isoprenaline. This reagent is utilized in studies investigating severe acute hemorrhages associated with gastroduodenal ulcers and provides insights into the mechanisms underlying cardiovascular diseases. -
Osteogenic Growth Peptide
Osteogenic Growth Peptide (OGP) is a naturally occurring 14-amino acid peptide that promotes osteogenesis primarily through its interaction with the receptor for advanced glycation end-products (RAGE). OGP plays a crucial role in stimulating bone formation and enhancing osteoblast activity. Research applications include studies on bone regeneration, osteoporosis, and potential therapeutic interventions for skeletal disorders. -
Dipeptide
H-Val-Ala-OH, also known as Valyl-alanine, is a dipeptide consisting of L-Valine and L-Alanine residues. It functions as a metabolite and may exhibit a bitter taste profile. This compound is utilized in biochemical research to study peptide interactions and metabolic pathways. -
Dipeptide
H-Hyp-Gly-OH is a dipeptide consisting of hydroxyproline and glycine. This compound enhances the proliferation of mouse primary fibroblasts cultured on collagen gel, suggesting its utility in skin regeneration studies. H-Hyp-Gly-OH may also contribute to metabolic research and has potential applications in improving skin health through hydrolyzed collagen supplementation. -
Dipeptide
H-Phe-Arg-OH is a dipeptide comprised of phenylalanine and arginine that serves as an important substrate in biochemical studies. This compound can be utilized to investigate the enzymatic activity of Angiotensin-converting enzyme (ACE). H-Phe-Arg-OH is valuable in metabolic research applications, particularly in understanding peptide processing and regulatory mechanisms within the renin-angiotensin system. -
Trastuzumab Signature Peptide
FTISADTSK is an endogenous stable signature peptide associated with Trastuzumab, serving as a valuable biomarker for monitoring therapeutic response. This peptide can be utilized in selected reaction monitoring (SRM) assays, facilitating quantitative analysis in oncology research. Its application extends to studies focused on trastuzumab treatment efficacy and patient stratification in breast cancer therapies.
