MBP (83-99)

Catalog No.: A64864
Peptide
MBP (83-99) is a peptide that targets the immunodominant epitope of myelin basic protein (MBP). This peptide is essential for the study of T cell responses, particularly in the context of multiple sclerosis research, as it stimulates the proliferation of T cells and the secretion of interferon-gamma (IFN-γ). It serves as a valuable tool for investigating autoimmune mechanisms and T cell immunology.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMBP (83-99) is a peptide that targets the immunodominant epitope of myelin basic protein (MBP). This peptide is essential for the study of T cell responses, particularly in the context of multiple sclerosis research, as it stimulates the proliferation of T cells and the secretion of interferon-gamma (IFN-γ). It serves as a valuable tool for investigating autoimmune mechanisms and T cell immunology.
Product Information
Catalog NumA64864
FormulaC93H143N25O24
Molecular Weight1995.28
CAS Number178823-45-5
Sequence shorteningENPVVHFFKNIVTPRTP
SMILESC([C@@H](NC([C@H](CCC(O)=O)N)=O)CC(N)=O)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(O)=O)CCC5)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC4)[C@@H](C)O)=O)[C@H](C)C)=O)[C@H](CC)C)=O)CC(N)=O)=O)CCCCN)=O)=O)CC6=CC=CC=C6)=O)=O)[C@@H](C)C)=O)C(C)C)=O)CCC1
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