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KRAS G12C Peptide

Catalog No.: A64868
KRAS G12C Peptide
KRAS G12C Peptide specifically targets the KRAS G12C oncogenic mutation, derived from the Kirsten rat sarcoma virus (KRAS) gene. This peptide elicits immune responses, including the secretion of IFN-γ and enhanced cytotoxicity, making it a valuable tool for investigating the immune dynamics against KRAS G12C-mutant tumors. It is particularly applicable in cancer research focused on developing immunotherapies and understanding tumor-immune interactions.
KRAS G12C Peptide 1932689-40-1 KRAS G12C Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS G12C Peptide specifically targets the KRAS G12C oncogenic mutation, derived from the Kirsten rat sarcoma virus (KRAS) gene. This peptide elicits immune responses, including the secretion of IFN-γ and enhanced cytotoxicity, making it a valuable tool for investigating the immune dynamics against KRAS G12C-mutant tumors. It is particularly applicable in cancer research focused on developing immunotherapies and understanding tumor-immune interactions.
Product Information
Catalog NumA64868
FormulaC38H69N11O11S
Molecular Weight888.09
CAS Number1932689-40-1
SequenceVal-Val-Val-Gly-Ala-Cys-Gly-Val-Gly-Lys
Sequence shorteningVVVGACGVGK
SMILESO=C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(N[C@@H](C)C(N[C@@H](CS)C(NCC(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
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