Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
tert-Butyl N-[2-(aminooxy)ethyl]carbamate is utilized as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This reagent enhances the design of bifunctional molecules that can selectively degrade specific proteins within cellular pathways. Its versatility in linking ligands and E3 ubiquitin ligases makes it valuable in various research applications, including targeted protein degradation studies and drug discovery efforts. -
PROTAC Linker
tert-Butyl N-methyl-N-(piperidin-4-ylmethyl)carbamate serves as a versatile PROTAC linker for the development of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by connecting an E3 ligase recruiter with a target protein binder. It is instrumental in research focused on targeted protein degradation, enabling the exploration of novel therapeutic strategies in various disease contexts. -
PROTAC Linker
6-Bromohexan-1-amine hydrobromide is a synthetic linker specifically designed for use in PROTAC (Proteolysis Targeting Chimera) technology. This compound facilitates the creation of bifunctional molecules that induce targeted protein degradation, allowing for the selective modulation of protein levels in cell signaling pathways. Its applications extend to cancer research, drug discovery, and the development of novel therapeutic strategies by enabling precise control over protein interactions and degradation. -
PROTAC Linker
1-(2-Aminoethyl)piperidin-4-ol is a versatile PROTAC linker that facilitates the development of targeted protein degradation strategies. It enhances the stability and efficacy of PROTACs by connecting target proteins to E3 ligases, thereby promoting ubiquitination and subsequent degradation. This reagent is essential for researchers exploring protein regulation and therapeutic applications in cancer and other diseases. -
PROTAC Linker
Tert-Butyl 6-amino-2-azaspiro[3.4]octane-2-carboxylate serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation strategies. This compound enhances the synthesis of PROTACs by providing a stable connection between target proteins and E3 ligases. Its structural features support the efficient formation of bifunctional molecules, making it an essential tool for researchers investigating targeted degradation pathways in cellular processes and disease models. -
PROTAC Linker
CbzNH-PEG3-OH is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the stability and solubility of PROTACs, promoting effective protein degradation in various cellular contexts. It is utilized in research applications focused on targeted protein degradation, providing a valuable tool for studying protein function and developing therapeutic strategies. -
PROTAC Linker
Benzyl 3-(hydroxymethyl)azetidine-1-carboxylate functions as a versatile PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimera (PROTAC) molecules. Its structural attributes enhance the efficiency of targeted protein degradation, making it a valuable tool in drug discovery and development. This compound is particularly useful in research focused on targeted therapies and mechanistic studies involving protein regulation. -
PROTAC Linker
4-(tert-Butyldimethylsilyloxy)-1-butyne serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins by linking E3 ligases and protein targets. Its applications are significant in the fields of drug discovery and molecular biology, particularly for studies focused on targeted protein degradation and therapeutic intervention. -
PROTAC Linker
tert-Butyl (4-hydroxycyclohexyl)carbamate functions as a PROTAC linker, facilitating the design and synthesis of targeted protein degradation agents. This compound is essential for creating bifunctional molecules that recruit specific E3 ligases to target proteins for degradation. Its use is pivotal in research applications focused on studying protein function and developing therapeutic strategies for diseases involving dysregulated protein levels. -
PROTAC Linker
TBS-PEG2-OH is a polymeric linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of the target protein and an E3 ligase through a polyethylene glycol (PEG) backbone, enhancing the stability and solubility of the PROTAC. It is valuable in drug development research focused on targeted protein degradation and novel therapeutic strategies. -
PROTAC Linker
3-(4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)phenyl)propanoic acid serves as a PROTAC linker, facilitating the creation of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by promoting the recruitment of E3 ligases. Its application is pivotal in the development of novel therapeutics aimed at addressing various diseases by modulating protein levels within biological systems. -
PROTAC Linkers
Fmoc-NH-PEG4-alcohol is a polyethylene glycol (PEG) based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound serves as a versatile scaffold, facilitating the construction of bifunctional molecules that can selectively induce the degradation of target proteins. Its unique chemical properties support various research applications in targeted protein degradation and therapeutic development. -
PROTAC Linkers
m-PEG10-CH2COOH is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimera) molecules. This compound facilitates the conjugation of ligands to target proteins, enhancing the efficiency of protein degradation pathways. Its application in PROTAC development supports research in targeted protein modulation and therapeutic intervention in various diseases. -
PROTAC Linker
{3-[(tert-Butyldimethylsilyl)oxy]cyclobutyl}methanol serves as a PROTAC linker, designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This molecule facilitates the recruitment of E3 ubiquitin ligases, thereby enabling targeted protein degradation. Its unique structure enhances solubility and stability, making it a valuable tool in chemical biology and therapeutic development research. -
PROTAC Linker
Cbz-NH-PEG12-C2-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It facilitates the formation of targeted protein degraders by linking an E3 ligase ligand to a protein target, thus enabling selective degradation of specific intracellular proteins. This reagent is essential for researchers investigating targeted protein degradation mechanisms and developing novel therapeutic strategies in the fields of cancer and other diseases. -
PROTAC Linker
4-Bromophenylacetonitrile is a PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation, enabling researchers to manipulate cellular protein levels and investigate biological pathways. Its application is pivotal in drug discovery and development, particularly for therapeutic interventions aimed at degrading specific proteins within various cellular environments. -
PROTAC Linker
2-{2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.3]heptan-6-yl}acetic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the targeted degradation of specific proteins by linking E3 ligases with the desired substrates, thereby enabling the modulation of cellular processes. Its application in research provides valuable insights into protein function and regulation, making it a vital tool for drug discovery and development. -
PROTAC Linker
tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate functions as a PROTAC linker, playing a critical role in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, thereby aiding in investigations of protein function and biological pathways. Its use in PROTAC synthesis enables researchers to explore targeted therapeutics for various diseases, including cancer and neurodegenerative disorders. -
PROTAC Linker
3-((tert-Butoxycarbonyl)amino)propyl 4-methylbenzenesulfonate is a versatile PROTAC linker designed for the synthesis of PROTAC molecules. Its structure facilitates the recruitment of E3 ligases, enhancing protein degradation through the ubiquitin-proteasome pathway. This reagent is essential for researchers focused on targeted protein degradation and therapeutic development in cancer and other diseases. -
PROTAC Linker
18-((2,5-Dioxopyrrolidin-1-yl)oxy)-18-oxooctadecanoic acid is a specialized linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the effective conjugation of target proteins to E3 ligases, promoting selective degradation pathways. Its application extends to chemical biology research, particularly in the development of targeted protein degradation strategies. -
PROTAC Linker
Heptadecanedioic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, providing researchers with a powerful tool for studying protein function and regulation. Its unique structure enhances the efficiency of PROTAC development in various cellular contexts, making it valuable for drug discovery and therapeutic applications. -
PROTAC Linker
Cyclohexane-1,4-diyldimethanamine functions as a PROTAC linker, facilitating the synthesis of bifunctional small molecules that induce targeted protein degradation. Its structural attributes enhance the stability and efficacy of PROTAC compounds, making it valuable in drug discovery and development. This linker is essential for studies aimed at elucidating protein function and therapeutic intervention strategies in various diseases. -
PROTAC Linker
6-Bromohex-1-yne is a versatile PROTAC linker designed for the synthesis of targeted protein degraders. Its unique structure facilitates the formation of linkages between E3 ligase recruiters and target proteins, enabling effective modulation of protein levels within cells. This compound is essential for researchers aiming to explore targeted protein degradation mechanisms in various biological pathways. -
PROTAC Linker
3-Boc-3,9-Diazaspiro[5.5]undecane hydrochloride serves as an innovative PROTAC linker, facilitating the formation of proteolysis-targeting chimeras (PROTACs). This compound is crucial for advancing research in targeted protein degradation by providing a robust connecting moiety in PROTAC synthesis. Its unique structural properties enhance the efficacy of bifunctional molecules, making it valuable for studying protein interactions and degradation pathways in various biological contexts. -
PROTAC Linker
2-(3-Chloropropyl)-1,3-dioxolane serves as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound is crucial for the development of targeted protein degradation strategies, allowing researchers to create bifunctional molecules that recruit E3 ligases to specific target proteins. Its application enhances the study of protein regulation and modulation in various biological contexts. -
PROTAC Linker
3,3'-Oxybis(propan-1-ol) is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enabling targeted degradation pathways in cellular models. Its application is critical in the development of advanced therapeutic strategies for various diseases, particularly in the realm of cancer research. -
PROTAC Linker
tert-Butyl 3-(methylamino)propanoate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound enables the effective conjugation of target proteins with E3 ligases, enhancing the specificity and efficacy of PROTACs in biochemical research. Its application is crucial in investigations focused on protein modulation and therapeutic development within the context of cancer and other diseases. -
PROTAC Linker
(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in connecting E3 ligase recruitment and target proteins, enabling targeted protein degradation. Its application is pivotal in chemical biology studies focusing on protein regulation and therapeutic intervention. -
PROTAC Linker
10-Bromodecanoic acid serves as a versatile linker in the synthesis of PROTACs, particularly in the development of targeted protein degraders. This reagent facilitates the construction of PROTAC molecules, such as the PROTAC KDM4 degrader-1, enabling specific degradation of target proteins through the ubiquitin-proteasome pathway. Its unique structure allows for enhanced stability and solubility, making it suitable for various biochemical applications in drug discovery and development. -
PROTAC Linker
1-Cbz-Azetidine-3-CH2NH2 is a versatile PROTAC linker that facilitates the construction of proteolysis-targeting chimeras (PROTACs). Its unique structural features allow for effective engagement of target proteins for ubiquitination and subsequent degradation. This compound is ideal for research applications involving targeted protein degradation and molecular biology studies focused on modulating protein levels within cellular systems. -
PROTAC Linker
tert-Butyl 3-cyanoazetidine-1-carboxylate is a PROTAC linker designed for the creation of proteolysis-targeting chimeras (PROTACs). Its unique structure facilitates the recruitment of E3 ligases, enhancing targeted protein degradation. This compound is essential in the development of novel therapeutic modalities aimed at selectively modulating protein levels within cells, making it valuable in both academic and pharmaceutical research settings. -
PROTAC Linker
cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the selectivity and efficacy of targeted protein degradation by linking E3 ligases with specific target proteins. It is suitable for research applications focused on targeted protein modulation and therapeutic development in cancer and other diseases. -
PROTAC Linker
tert-Butyl 4-(4-bromophenyl)piperidine-1-carboxylate acts as a PROTAC linker essential for the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of targeted protein degraders, enhancing the specificity and efficacy of therapeutic interventions in various biological contexts. Its structural properties make it an invaluable tool in drug discovery and development aimed at modulating protein function. -
PROTAC Linker
4-((tert-Butoxycarbonyl)amino)cyclohexanecarboxylic acid serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enables controlled degradation of target proteins, thereby aiding research into therapeutic interventions and cellular regulation mechanisms. Its application is vital in drug discovery and development strategies aimed at tackling diseases through targeted protein modulation. -
PROTAC Linker
1,4-Cyclohexanedimethanol serves as an essential PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). Its structural attributes allow for effective conjugation of target proteins to E3 ligases, enhancing the development of novel therapeutic strategies for targeted protein degradation. This compound is suitable for various applications in chemical biology and drug discovery research. -
PROTAC Linker
tert-Butyl 17-bromoheptadecanoate is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies, enhancing the specificity and efficacy of therapeutic interventions. Its unique structure allows for the effective conjugation of target proteins and ligands, making it a valuable reagent in chemical biology and drug discovery research. -
PROTAC Linker
tert-Butyl N-[(4-fluoropiperidin-4-yl)methyl]carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound enhances the selective degradation of specific proteins by linking an E3 ligase ligand to a protein of interest. It plays a critical role in chemical biology and therapeutic research, enabling novel approaches in drug discovery and development. -
PROTAC Linker
5-Bromopentan-1-amine hydrobromide is a versatile PROTAC linker designed for the synthesis of targeted protein degradation agents. Its structure facilitates the conjugation of target proteins and E3 ligase components, enabling the development of bifunctional molecules that promote selective ubiquitination and degradation. This reagent is essential for researchers investigating targeted therapy and novel drug discovery approaches in the fields of oncology and cell biology. -
PROTAC Linker
Decanedioic acid disodium acts as a PROTAC linker facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is critical in promoting targeted protein degradation through its ability to connect an E3 ligase and a protein of interest. Its application in drug development and research enhances studies focused on protein regulation and degradation pathways. -
PROTAC Linker
tert-Butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate is a specialized PROTAC linker designed to facilitate the development of targeted protein degradation applications. This compound enables the effective synthesis of PROTACs by serving as a versatile building block, promoting selective degradation of proteins within cellular contexts. Its unique structure supports research in protein homeostasis and therapeutic strategies targeting aberrant proteins in various diseases. -
PROTAC Linker
Methyl 4-piperazin-1-ylbenzoate serves as a versatile PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). This compound plays a critical role in connecting target proteins to E3 ligase, enabling targeted degradation of specific proteins within cells. It is essential for researchers focused on protein modulation, targeted therapy, and the advancement of novel drug delivery systems in chemical biology. -
PROTAC Linker
2-(Prop-2-yn-1-yloxy)acetic acid functions as a PROTAC linker, facilitating the design and assembly of PROTAC molecules. This compound plays a crucial role in the development of targeted protein degradation strategies, allowing for the selective modulation of protein activity in cellular systems. Its utility in chemical biology makes it a valuable tool for researchers exploring novel therapeutic interventions. -
PROTAC Linker
3-Benzyl-3,9-diazaspiro[5.5]undecane serves as a linker for PROTAC (Proteolysis Targeting Chimera) technology. This compound facilitates the design and synthesis of PROTACs, which are innovative molecules utilized for targeted protein degradation in cellular systems. Its unique structural features contribute to the effective engagement of E3 ubiquitin ligases, enabling researchers to explore novel therapeutic pathways in drug development and basic biological research. -
PROTAC Linker
tert-Butyl (4-hydroxybutyl)carbamate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation by connecting E3 ligases to specific protein targets, enhancing the efficacy of therapeutic interventions. Its structural properties support the development of novel research tools in drug discovery and cellular regulation studies. -
PROTAC Linker
1,4-Bis(aminomethyl)benzene serves as a versatile PROTAC linker, integral to the design and synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the targeted degradation of specific proteins by linking an E3 ligase ligand to a protein of interest. Its application is essential in studies focused on protein homeostasis, cellular signaling, and therapeutic intervention in various diseases. -
PROTAC Linker
2-(4-Ethynylphenyl)acetonitrile acts as a versatile PROTAC linker, facilitating the development of PROTAC (PROteolysis TArgeting Chimeras) molecules. Its structural properties enhance the selective degradation of target proteins by the ubiquitin-proteasome system. This compound is valuable for research in targeted protein degradation, enabling studies in cancer biology and therapeutic development. -
PROTAC Linker
1-Boc-4-(Aminomethyl)piperidine hydrochloride functions as a PROTAC linker, facilitating the design and synthesis of targeted protein degraders. This compound is essential for creating bifunctional molecules that engage ligands for protein of interest and E3 ligases, thereby enabling targeted degradation pathways. It is widely used in research applications aimed at elucidating protein functions and developing novel therapeutic strategies through targeted protein modulation. -
PROTAC Linker
3-(benzyloxy)propanoic acid serves as a PROTAC linker, facilitating the construction of bifunctional small molecules that can induce targeted protein degradation. This compound enhances the stability and efficiency of PROTACs, making it valuable for research in the field of targeted therapeutics. Its incorporation into PROTAC design supports investigations into cellular mechanisms and treatment strategies for various diseases, including cancer. -
PROTAC Linker
tert-Butyl 2-(4-aminophenyl)acetate serves as a key PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins via the ubiquitin-proteasome system. Its significant role in the synthesis of PROTACs makes it valuable for research applications in targeted protein degradation and therapeutic development. -
PROTAC Linker
NHBoc-PEG3-I is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimera) compounds. This linker facilitates the conjugation of targeting ligands to E3 ligase recruiters, enhancing the efficacy of PROTACs in targeted protein degradation. Its application is critical in research focused on developing novel therapeutic strategies for diseases driven by abnormal protein expression.
