Fig. 1 · Structure
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1,4-Bis(aminomethyl)benzene
PROTAC Linker
1,4-Bis(aminomethyl)benzene serves as a versatile PROTAC linker, integral to the design and synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the targeted degradation of specific proteins by linking an E3 ligase ligand to a protein of interest. Its application is essential in studies focused on protein homeostasis, cellular signaling, and therapeutic intervention in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 539-48-0 |
| Applications | PROTAC Linker |
| Formula | C8H12N2 |
| Molecular Weight | 136.20 |
| SMILES | NCC1=CC=C(C=C1)CN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.