Fig. 1 · Structure
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3-Benzyl-3,9-diazaspiro5.5undecane
PROTAC Linker
3-Benzyl-3,9-diazaspiro[5.5]undecane serves as a linker for PROTAC (Proteolysis Targeting Chimera) technology. This compound facilitates the design and synthesis of PROTACs, which are innovative molecules utilized for targeted protein degradation in cellular systems. Its unique structural features contribute to the effective engagement of E3 ubiquitin ligases, enabling researchers to explore novel therapeutic pathways in drug development and basic biological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 189333-49-1 |
| Applications | PROTAC Linker |
| Formula | C16H24N2 |
| Molecular Weight | 244.38 |
| SMILES | C=1C=CC(=CC1)CN2CCC3(CCNCC3)CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.