Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by promoting the engagement of E3 ligases. It is essential for researchers aiming to design and synthesize innovative PROTACs for therapeutic applications. -
PROTAC Linker
2-(7-(Tert-butoxycarbonyl)-7-azaspiro[3.5]nonan-2-yl)acetic acid functions as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the design of bifunctional molecules that can modulate protein degradation pathways. Its structural features support efficient protein-protein interactions, making it suitable for targeted protein degradation studies and drug discovery applications. -
PROTAC Linker
Methyl 16-bromohexadecanoate serves as a PROTAC linker, facilitating the synthesis of bifunctional degraders. This compound is crucial for the development of targeted protein degradation strategies, enabling selective modulation of protein levels within cellular systems. Its application extends to various research areas, including drug discovery and the study of protein interactions. -
PROTAC Linker
16-Bromohexadecanoic acid is a PROTAC linker designed for the synthesis of proteolysis targeting chimeras (PROTACs). Its unique structure enhances the specificity and efficacy of these bifunctional molecules in targeted protein degradation. This compound is integral for research applications involving the modulation of protein levels and the investigation of cellular protein homeostasis. -
PROTAC Linker
Decane-1,10-diamine serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the stability and efficacy of PROTACs by providing a flexible and robust connection between the target protein ligand and an E3 ligase ligand. Its application is crucial in the development of targeted protein degradation strategies in chemical biology research. -
PROTAC Linker
Hex-5-yn-1-yl 4-methylbenzenesulfonate is a PROTAC linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation by bridging an E3 ligase with a protein of interest, enabling the selective modulation of protein levels within cells. Hex-5-yn-1-yl 4-methylbenzenesulfonate is essential for advancing research on targeted therapies and uncovering cellular mechanisms through the manipulation of protein homeostasis. -
PROTAC Linker
Benzyl (3-aminopropyl)carbamate functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting E3 ligases with target proteins, thereby enabling selective degradation of unwanted proteins within cells. It is an essential tool for researchers investigating targeted protein degradation and its therapeutic potential in various disease models. -
PROTAC Linker
Tert-butyl-dimethyl-pent-4-ynoxy-silane is a versatile PROTAC linker that facilitates the construction of proteolysis-targeting chimeras (PROTACs). This compound enables the effective conjugation of target proteins to E3 ligases, thereby promoting targeted protein degradation. It is utilized in chemical biology research to investigate protein function and develop novel therapeutic strategies. -
PROTAC Linker
tert-Butyl 3-(3-hydroxypropyl)azetidine-1-carboxylate serves as a PROTAC linker for the development of protein-targeting chimeras. Its structure facilitates the conjugation of ligands to targeted proteins, promoting their selective degradation via the ubiquitin-proteasome pathway. This compound has significant applications in exploring protein function and developing therapeutics through targeted protein modulation. -
PROTAC Linker
N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) is a PROTAC linker designed for the efficient synthesis of PROTACs. This compound facilitates the development of targeted protein degradation strategies by enabling the formation of bifunctional molecules that recruit E3 ubiquitin ligases to specific target proteins. Its application extends to various research areas, including drug discovery and therapeutic development in cancer and other diseases. -
PROTAC Linker
1,7-Heptanediol is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for conjugating target proteins to E3 ligases, thereby enhancing the targeted degradation of specific proteins in cellular contexts. Its application in drug discovery and molecular biology research supports studies focused on protein function modulation and therapeutic intervention strategies. -
PROTAC Linker
Methyl 12-bromododecanoate is a PROTAC linker characterized by its ability to facilitate the synthesis of protein-targeting chimeras. This compound enhances the engagement of E3 ligases in targeted protein degradation applications, making it a valuable tool in drug discovery and development efforts aimed at modulating protein levels within cells. Its distinct chemical properties support innovative research in targeted therapies and molecular biology studies. -
PROTAC Linker
tert-Butyl 3-(2-hydroxyethoxy)azetidine-1-carboxylate serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the development of targeted protein degradation strategies, enabling selective modulation of protein activity. Its effectiveness in creating bifunctional molecules makes it valuable for research in drug discovery and the study of protein homeostasis. -
PROTAC Linker
3,3'-(Propane-1,3-diylbis(oxy))bis(propan-1-ol) functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras. This compound plays a critical role in assembling a ligand that recruits E3 ligases for targeted protein degradation. Its application in the synthesis of PROTACs supports investigations into targeted therapies and the modulation of specific protein levels for research in cellular signaling pathways and disease mechanisms. -
PROTAC Linker
PEG2-MeN-Boc is a polyethylene glycol-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound enhances the solubility and stability of PROTACs, facilitating the targeted degradation of specific proteins. Its application is crucial in the development of novel therapeutic agents aimed at modulating protein levels for cancer and other diseases. -
PROTAC Linker
2-(4-(2-Methoxy-2-oxoethyl)phenyl)acetic acid is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting target proteins to E3 ligases, thus enhancing targeted protein degradation. It is valuable in research focused on protein modulation and therapeutic development through innovative drug design strategies. -
PROTAC Linker
(9H-Fluoren-9-yl)methyl tert-butyl ethane-1,2-diyldicarbamate functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in connecting proteins of interest to E3 ligases for targeted degradation, thereby enhancing the specificity and efficacy of therapeutic interventions in various diseases. Its application in the synthesis of PROTACs underscores its significance in chemical biology and drug discovery research. -
PROTAC Linker
Cbz-NH-PEG2-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimeras). This compound facilitates targeted protein degradation by linking a protein-targeting ligand with an E3 ligase ligand, enhancing the selective degradation of specific proteins. Its application in PROTAC development makes it a valuable tool for researchers investigating therapeutic strategies in various diseases, including cancer. -
PROTAC Linker
tert-Butyl (7-hydroxyheptyl)carbamate serves as a PROTAC linker, facilitating the connection between target proteins and ubiquitin ligases for targeted protein degradation. This compound is integral to the design and synthesis of PROTAC molecules, enabling researchers to manipulate protein levels with precision. Its unique structure enhances the efficiency and specificity of protein degradation in biological assays. -
PROTAC Linker
1-Bromo-5-chloropentane is a PROTAC linker utilized in the synthesis of proteolysis-targeting chimera (PROTAC) compounds. It facilitates the formation of covalent bonds between E3 ligases and target proteins, enabling targeted protein degradation. This reagent is essential for researchers developing novel therapeutic agents aimed at modulating protein levels in various cellular contexts. -
PROTAC Linker
Boc-PEG2-I is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It facilitates the conjugation of ligands to target proteins, enhancing the selective degradation of undesirable proteins via ubiquitin-proteasome pathways. Its versatile application in chemical biology research enables the development of novel therapeutics aimed at various disease targets. -
PROTAC Linker
tert-Butyl 4-(2-(methylamino)ethyl)piperazine-1-carboxylate serves as a versatile PROTAC linker facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the intracellular degradation of target proteins by leveraging the targeted protein degradation pathway. Its crucial role in developing innovative therapeutic strategies makes it valuable for advancing research in targeted protein modulation and cancer therapeutics. -
PROTAC Linker
Boc-PEG3-mesylate is a PROTAC linker that facilitates the construction of proteolysis-targeting chimeras (PROTACs). This compound serves as a valuable tool for connecting the ligand and E3 ligase components, enhancing targeted protein degradation. Its application in PROTAC development supports research in drug discovery and therapeutic interventions for various diseases by enabling selective modulation of protein levels in cells. -
PROTAC Linker
Sodium 2-(2-hydroxyethoxy)acetate is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound serves as a versatile building block in the synthesis of PROTACs, enabling targeted protein degradation for therapeutic applications. Its ability to link small molecules with E3 ligases is crucial for advancing research in drug discovery and development. -
PROTAC Linker
20-Methoxy-20-oxoicosanoic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This chemical compound plays a crucial role in linking target proteins to E3 ligases, promoting targeted protein degradation. Its applications are primarily found in biochemical research focused on studying protein turnover and validating protein function. -
PROTAC Linker
1-Boc-3-((Methylamino)methyl)azetidine serves as a PROTAC linker, facilitating the creation of Proteolysis Targeting Chimeras (PROTACs). This compound is integral in linking target proteins with E3 ubiquitin ligases, thereby promoting targeted degradation. Its application is crucial in drug discovery and development, particularly for generating novel therapeutics that modulate protein levels within cells. -
PROTAC Linker
Ethyl 6-aminohexanoate hydrochloride is a PROTAC linker that facilitates the development of PROTACs by providing a flexible molecular scaffold. This compound is essential for the targeted degradation of specific proteins via the ubiquitin-proteasome system, enabling innovative research in protein modulation and cellular pathways. It is particularly valuable in studies focused on therapeutics aimed at manipulating protein dynamics within various biological contexts. -
PROTAC Linker
Boc-C14-Br is a specialized PROTAC linker that facilitates the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the formation of PROTACs by providing a flexible and effective means of connecting ligands to E3 ubiquitin ligases. Its significant impact on protein degradation pathways makes it valuable for research in targeted protein modulation and therapeutic development. -
PROTAC Linker
2-(2-(1,3-Dioxolan-2-yl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a linker for PROTAC technology, facilitating targeted protein degradation. This compound is designed to enable the formation of heterobifunctional molecules, which promote selective binding to target proteins and E3 ligases. Its application in the synthesis of PROTACs makes it valuable for research in targeted therapies and drug development. -
PROTAC Linkers
m-PEG3-SH is a polyethylene glycol (PEG)-derived linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of target proteins to E3 ubiquitin ligases, promoting targeted protein degradation. Its application enhances the development of therapeutics for various diseases by enabling selective modulation of protein activity. -
PROTAC Linker
1,4-Diamino-2-butyne dihydrochloride is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is essential for connecting target proteins to E3 ligases, thereby promoting ubiquitin-mediated degradation of specific proteins in cellular studies. It plays a critical role in drug discovery and development, particularly in the characterization of targeted protein degradation mechanisms. -
PROTAC Linkers
Cbz-NH-PEG3-CH2COOH is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound facilitates the construction of bifunctional molecules that promote targeted protein degradation via the ubiquitin-proteasome pathway. Its unique structure allows for the efficient formation of PROTACs, significantly advancing drug discovery and development research focused on protein modulation. -
PROTAC Linker
4-Hydroxybutanal serves as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation by enabling the selective recruitment of E3 ligases. Its role in PROTAC development is critical for advancing research in cellular regulation and therapeutic strategies. -
PROTAC Linker
PEG2-NH-Cbz is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the conjugation of E3 ligases to target proteins, promoting ubiquitination and subsequent degradation. Its application is crucial in the field of targeted protein degradation, enabling innovative approaches in drug discovery and cellular biology research. -
PROTAC Linker
Tert-butyl methyl(3-(methylamino)propyl)carbamate is a specialized PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, crucial for studies focusing on targeted protein modulation and therapeutic intervention. Its application enhances the development of novel drug candidates in the realm of targeted therapy research. -
PROTAC Linker
3-(4-Bromophenyl)prop-2-yn-1-ol serves as a potent linker in the development of PROTACs (Proteolysis Targeting Chimeras). Its unique structure facilitates the effective attachment of ligand and E3 ligase components, enabling targeted protein degradation. This compound is crucial for researchers investigating protein regulation and therapeutic applications in drug discovery. -
PROTAC Linker
2-(2-Chloroethoxy)acetonitrile is a PROTAC linker designed for the efficient synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target ligands and E3 ligase recruiters, enabling targeted protein degradation. It is applicable in research aimed at elucidating cellular pathways and developing novel therapeutic strategies. -
PROTAC Linker
Methyl propionate-PEG12 is a PEG-based PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). Its chemical structure enhances solubility and stability, allowing for the effective recruitment of E3 ligases. This linker is essential for researchers developing targeted protein degradation strategies in various cellular pathways and therapeutic applications. -
PROTAC Linkers
Mal-PEG12-NH-Boc is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances solubility and improves the pharmacokinetic properties of PROTACs, facilitating targeted protein degradation. It is suitable for applications in drug development, particularly in the study of protein modulation and therapeutic innovations. -
PROTAC Linkers
NH2-PEG5-C1-Boc is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of targeting ligands to E3 ligases, enabling the selective degradation of target proteins through the ubiquitin-proteasome system. It is applicable in the development of innovative therapeutic strategies for various diseases by enhancing the efficacy and specificity of protein degradation. -
PROTAC Linkers
Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs, specifically targeting the engagement of E3 ligases for protein degradation. This compound features an azide group, facilitating click chemistry reactions, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it a versatile tool for chemical biology applications and the development of targeted protein degradation strategies. -
PROTAC Linker
Azido-PEG3-methyl ester is a PEG-based linker designed for PROTAC synthesis. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified targets. Its efficient reactivity makes it a valuable tool for developing targeted protein degradation strategies in chemical biology research. -
PROTAC Linker
7-(Piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonane functions as a PROTAC linker, crucial for targeted protein degradation applications. Its unique structural properties facilitate the effective coupling of E3 ligases and substrate proteins, enhancing the specificity and efficiency of PROTAC conjugates. This compound is instrumental in research focused on therapeutic strategies that leverage protein degradation for disease intervention. -
PROTAC Linkers Chemical
Bromo-C10-OBn is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a bromine moiety that facilitates ligand-target interactions, enabling selective degradation of proteins of interest. Bromo-C10-OBn is particularly useful for researchers studying targeted protein degradation mechanisms and developing novel therapeutic strategies in cancer and other diseases. Its unique structure supports the design of effective PROTACs for a range of biological applications. -
PROTAC Linker
Benzyloxy carbonyl-PEG3-C2-Boc is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the effective conjugation of protein ligands, enhancing their ability to target specific proteins for degradation within cellular systems. It is crucial for researchers exploring targeted protein degradation and its potential therapeutic applications in various diseases. -
PROTAC Linker
Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker designed for targeted protein degradation applications. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-bearing molecules or those incorporating DBCO or BCN groups, respectively. Its utility in the synthesis of novel PROTACs enhances research in targeted therapeutic strategies and programmable protein modulation. -
PROTAC Linkers
Benzyl-PEG24-alcohol is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the recruitment of E3 ligases, enabling targeted protein degradation. Its application is pivotal in developing novel therapeutic strategies for diseases associated with aberrant protein regulation. -
PROTAC Linkers
Boc-NH-PEG11-CH2CH2N3 is a PEG-based linker designed for use in the synthesis of PROTACs through targeted protein degradation. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. Its unique properties make it suitable for applications in chemical biology and drug discovery. -
PROTAC Linkers
Azido-PEG7-azide is a PEG-based linker designed for the synthesis of PROTACs, functioning through click chemistry. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. Its versatile reactivity makes it a valuable tool for researchers in chemical biology and drug development. -
PROTAC Linker
Methylamino-PEG4-Boc is a polyethylene glycol (PEG) based linker utilized in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins with E3 ligases, enabling targeted protein degradation. Methylamino-PEG4-Boc is instrumental in advancing research in the field of targeted therapeutics and cellular protein regulation.
