Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
1,1-Dimethylethyl 4-iodobutanoate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its unique chemical properties allow for the efficient conjugation of targeted proteins, enabling researchers to engage the ubiquitin-proteasome system for targeted degradation. This compound is valuable in studies focused on protein modulation and therapeutic applications in oncology and cellular regulation. -
PROTAC Linker
tert-Butyl (3-(piperidin-4-yl)propyl)carbamate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the dual-targeting capability of PROTACs, enabling the selective degradation of specific proteins within cells. Its application is essential in studies focused on targeted protein degradation and the development of novel therapeutic strategies in various disease models. -
PROTAC Linker
Methyl 10-bromodecanoate functions as a PROTAC linker, facilitating the development of targeted protein degrader molecules. Its unique structural properties enable efficient conjugation to E3 ligase and target proteins, thereby promoting protein degradation pathways. This compound is valuable in the field of chemical biology for the synthesis of novel PROTACs aimed at exploring protein function and therapeutic strategies. -
PROTAC Linker
Sebaconitrile is a key PROTAC linker utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). Its structure facilitates efficient binding and degradation of target proteins via the ubiquitin-proteasome pathway. This compound is essential for research applications focused on the modulation of protein levels and therapeutic targeting of specific proteins for cancer and other diseases. -
PROTAC Linker
tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate is a specialized PROTAC linker that facilitates the development of proteolysis-targeting chimera (PROTAC) molecules. This reagent plays a critical role in connecting target proteins with E3 ligases, enabling targeted protein degradation. Its unique structure enhances the efficiency and specificity of PROTAC synthesis, making it essential for research in therapeutic strategies aimed at selective protein modulation. -
PROTAC Linker
OH-PEG2-C3-NH2 is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). Its chemical structure enables efficient conjugation to target proteins, enhancing targeted degradation pathways. This linker is pivotal for studies focused on protein modulation and therapeutic development through targeted protein degradation strategies. -
PROTAC Linker
tert-Butyl (1-(2-aminoethyl)piperidin-4-yl)carbamate functions as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). This compound is integral for connecting target proteins to E3 ligases, enhancing specific ubiquitination and subsequent degradation of the target. Its application is crucial in the field of targeted protein degradation research, offering insights into protein regulation and therapeutic intervention. -
PROTAC Linker
Cbz-NH-PEG1-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, enhancing the degradation of unwanted proteins in cellular contexts. Its application is crucial for researchers focusing on targeted protein degradation and the development of novel therapeutic strategies. -
PROTAC Linker
tert-Butyl 5-hydroxypentanoate serves as a key PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. Its structural features enable effective conjugation with various protein-binding domains, enhancing the specificity and efficiency of PROTAC design. This compound is valuable in chemical biology research aimed at modulating protein levels within cells for therapeutic applications. -
PROTAC Linker
1,8-Octanedithiol is a versatile PROTAC linker that facilitates the assembly of proteolysis-targeting chimeras (PROTACs). Its unique structure allows for effective conjugation to target proteins and E3 ligases, enhancing the specificity and efficacy of targeted degradation strategies in research. This compound is essential for the development of novel therapeutic agents aimed at modulating protein levels in various biological pathways. -
PROTAC Linker
Dimethyl spiro[3.3]heptane-2,6-dicarboxylate functions as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the development of targeted protein degradation strategies, enhancing the efficacy and selectivity of therapeutic agents. Its structural properties make it suitable for various research applications involving the modulation of protein levels in cellular systems. -
PROTAC Linker
Br-PEG7-Br is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its structure facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. This compound is essential for researchers developing innovative therapeutic strategies in drug discovery and cellular biology studies. -
PROTAC Linker
(4-(((Tert-butoxycarbonyl)(methyl)amino)methyl)phenyl)boronic acid functions as a key PROTAC (Proteolysis Targeting Chimera) linker. This compound facilitates the assembly of PROTACs by connecting a target ligand to an E3 ligase ligand, thereby enabling the ubiquitin-proteasome system to selectively degrade the target protein. Its application is critical in studies aimed at exploring targeted protein degradation and drug discovery processes. -
PROTAC Linker
1,10-Dichlorodecane serves as a PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). Its unique chemical structure allows for effective conjugation of target proteins with E3 ligases, promoting targeted protein degradation. This compound is essential for studies focusing on targeted therapeutics and the modulation of protein levels in various biological systems. -
PROTAC Linker
6-Chlorohexanoic acid is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the development of targeted protein degradation technologies, making it a valuable reagent for drug discovery and biological research. Its structural properties enable efficient conjugation to various proteins, contributing to innovative therapeutic strategies. -
PROTAC Linker
tert-Butyl 4-(3-hydroxypropyl)piperazine-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation strategies by enabling selective binding to ubiquitin ligases. Its structural properties make it suitable for applications in drug discovery and the study of protein regulation mechanisms. -
PROTAC Linker
Methyl 3-(4-aminophenyl)propanoate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its unique structure enables effective conjugation to target proteins, thereby enhancing the potential for selective protein degradation. This compound is valuable in biochemical research focusing on targeted protein modulation and therapeutic applications in the study of various diseases. -
PROTAC Linker
6-((2,5-Dioxopyrrolidin-1-yl)oxy)-6-oxohexanoic acid is a bifunctional linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This reagent facilitates the selective degradation of target proteins by linking an E3 ligase to the protein of interest. Its unique structure offers versatility in tailoring PROTACs for specific biological applications, making it an essential tool for researchers exploring targeted protein degradation mechanisms. -
PROTAC Linker
tert-Butyl 16-bromohexadecanoate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins and E3 ligases, enhancing targeted degradation pathways. Its precise structure supports efficient development of novel therapeutic agents for various diseases, particularly in the field of targeted protein degradation research. -
PROTAC Linkers
HO-PEG10-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (PROteolysis TArgeting Chimeras). This compound facilitates the conjugation of target proteins with E3 ligases, enabling targeted protein degradation and modulation of cellular pathways. Its hydrophilic nature enhances solubility and biocompatibility, making it suitable for various research applications in drug discovery and targeted therapeutics. -
PROTAC Linker
3-Boc-aminomethylazetidine is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the targeting and degradation of specific proteins by linking E3 ligases to the desired protein targets, thus enabling selective modulation of protein levels. It is a valuable reagent for researchers studying targeted protein degradation and molecular interventions in various biological pathways. -
PROTAC Linker
((4-Bromobutoxy)methyl)benzene serves as a versatile PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation by linking a specific ligand to an E3 ligase, thereby enabling the selective removal of target proteins. It is valuable for researchers investigating targeted protein modulation and degradation pathways in various biological contexts. -
PROTAC Linker
Boc-C15-COOH is a linker designed for PROTAC (Proteolysis Targeting Chimeras) applications, facilitating the development of novel targeted protein degradation strategies. This compound enhances the specificity and efficacy of PROTACs by connecting target proteins to E3 ligases, leading to selective ubiquitination and subsequent proteasomal degradation. It is particularly useful in research focused on delineating protein function and developing therapeutic agents in cancer and other diseases through targeted protein modulation. -
PROTAC Linker
tert-Butyl 3-(piperidin-4-yloxy)azetidine-1-carboxylate hydrochloride is a versatile PROTAC linker designed for the development of functional proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins within cellular systems, enabling studies on protein function and regulation. It serves as a crucial component in the synthesis of PROTACs, aiding in the advancement of targeted protein degradation research. -
PROTAC Linker
tert-Butyl (8-iodooctyl)carbamate serves as a PROTAC linker, facilitating the assembly of bifunctional molecules designed to target specific proteins for degradation. Its structural properties enhance the bioactivity of PROTAC compounds by improving cellular uptake and target specificity. This reagent is essential for researchers aiming to develop innovative protein degradation strategies in therapeutic and biochemical studies. -
PROTAC Linker
tert-Butyl 3-(aminomethyl)azetidine-1-carboxylate hydrochloride serves as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). This compound is essential for creating bifunctional molecules that selectively degrade target proteins via the ubiquitin-proteasome system. Its efficacy in research applications includes enhancing targeted protein degradation for therapeutic purposes in cancer and other diseases. -
PROTAC Linker
1,6-Dichlorohexane is a PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). It plays a crucial role in enabling targeted protein degradation by linking E3 ligases to specific target proteins. This compound is essential for researchers investigating targeted therapeutics and the modulation of protein activity in cell biology studies. -
PROTAC Linker
(4-(3-Methoxy-3-oxopropyl)phenyl)boronic acid is a PROTAC (Proteolysis Targeting Chimera) linker that facilitates targeted protein degradation. This compound is crucial for the synthesis of PROTACs, enabling researchers to selectively remove unwanted proteins from cells. Its unique structure allows for effective engagement with E3 ubiquitin ligases and target proteins, making it a valuable tool in drug discovery, particularly in studies focused on therapeutic interventions for cancer and other diseases. -
PROTAC Linker
Methyl N-Boc-4-piperidinepropionate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound features a N-Boc protecting group and a piperidine moiety, enabling effective conjugation to E3 ligases and target proteins. Its utilization in PROTAC design supports studies in targeted protein degradation and offers potential applications in therapeutic development and chemical biology research. -
PROTAC Linker
2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure facilitates targeted protein degradation, making it valuable in the development of therapeutic compounds. This linker plays a crucial role in advancing research aimed at understanding protein dynamics and developing novel strategies for cancer treatment and other diseases. -
PROTAC Linker
Methyl 7-aminoheptanoate hydrochloride is a PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates targeted protein degradation, enabling specific modulation of protein levels within cellular systems. Its application in research contributes to advancements in drug discovery and therapeutic development by enabling the precise regulation of protein activity. -
PROTAC Linker
HOCH2-Cyclobutane-CH2COOMe is a versatile PROTAC linker that facilitates the creation of targeted protein degradation bioconjugates. This compound aids in the design of PROTACs (proteolysis-targeting chimeras) by connecting a target protein ligand to an E3 ligase recruitor, enhancing the efficiency of selective protein degradation. Its unique cyclobutane structure contributes to improved stability and cell permeability, making it suitable for various applications in chemical biology and drug discovery. -
PROTAC Linker
Methyl 2-cyanocyclopropanecarboxylate is a PROTAC linker that facilitates the design and synthesis of PROTAC molecules. Its unique structure allows for modular assembly, enabling targeted protein degradation via the ubiquitin-proteasome system. This compound is particularly useful in drug discovery and development for therapeutic applications that involve modulating protein levels in cellular systems. -
PROTAC Linker
tert-Butyl (2-(2-(methylamino)ethoxy)ethyl)carbamate is a PROTAC linker designed for the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of PROTACs, facilitating the targeted degradation of specific proteins within cells. Its effective incorporation enhances the design of molecular probes and therapeutic agents in drug discovery applications. -
PROTAC Linker
10-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)decanoic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances target protein degradation by connecting an E3 ligase ligand to a protein of interest, enabling the efficient ubiquitination and subsequent proteasomal degradation. Its utility in chemical biology aids in the study of protein dynamics and targeted protein degradation applications in drug discovery. -
PROTAC Linker
Ethyl but-3-ynoate is a versatile PROTAC linker employed in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates targeted protein degradation, thus providing a valuable tool in the study of protein function and therapeutic development. Its unique structure enhances the pharmacological properties of PROTACs, making it an essential building block in chemical biology research. -
PROTAC Linkers
m-PEG7-Br is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound enhances the solubility and stability of PROTACs, facilitating the development of biopharmaceuticals that regulate target protein degradation. Its application in research includes the optimization of PROTAC structures for improved efficacy in targeted protein modulation. -
PROTAC Linker
4-Boc-(trans)-Cyclohexanediamine-2-ethyl acetate serves as a PROTAC linker, facilitating the development of protein degradation agents. This compound enables the conjugation of target proteins to E3 ligases, promoting ubiquitination and subsequent proteasomal degradation. It is valuable in the synthesis of PROTACs for targeted protein modulation in various biological research applications. -
PROTAC Linker
Pent-4-yn-1-amine is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its alkyne functionality facilitates the formation of stable linkers essential for targeted protein degradation applications. This compound is instrumental in advancing research in targeted therapeutics and protein modulation studies. -
PROTAC Linker
tert-Butyl 4-(4-(hydroxymethyl)phenyl)piperazine-1-carboxylate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by promoting their ubiquitination and subsequent proteasomal degradation. Its application is essential in drug discovery and development for tackling previously undruggable targets in cancer and other diseases. -
PROTAC Linker
rel-(1S,2R)-2-(((tert-butoxycarbonyl)amino)methyl)cyclopropane-1-carboxylic acid serves as a PROTAC linker, facilitating the targeted degradation of proteins through the ubiquitin-proteasome pathway. This compound is essential for the construction of PROTACs, enabling researchers to modulate protein levels and examine cellular processes. Its structural attributes promote efficient and selective engagement with target proteins, making it a valuable tool in chemical biology and therapeutic development. -
PROTAC Linker
Benzyl (piperidin-4-ylmethyl)carbamate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ubiquitin ligases to target proteins, thereby promoting their selective degradation. It is essential for applications in targeted protein degradation research, advancing the development of novel therapeutics. -
PROTAC Linker
Methyl 4-(aminomethyl)bicyclo[2.2.2]octane-1-carboxylate is a PROTAC linker that facilitates targeted protein degradation through the construction of PROTAC molecules. This compound serves as a versatile building block for synthesizing heterobifunctional compounds, enabling the selective recruitment of E3 ligases to specific target proteins. It is essential for research applications focused on elucidating protein functions and developing therapeutics that harness the power of the ubiquitin-proteasome system. -
PROTAC Linker
p-Bromophenoxyaceticacid serves as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the selective degradation of target proteins, making it a valuable tool in drug discovery and development. Its application in PROTAC synthesis allows researchers to explore innovative therapeutic strategies for modulating protein levels in various biological contexts. -
PROTAC Linker
tert-Butyl (2-(2-iodoethoxy)ethyl)carbamate functions as a PROTAC linker, enabling the development of proteolysis-targeting chimera (PROTAC) molecules for targeted protein degradation. Its structure facilitates the conjugation of protein ligands to E3 ligases, promoting ubiquitination and subsequent proteasomal degradation of specific proteins. This compound is crucial for researchers focusing on protein regulation, therapeutic discovery, and drug development for various diseases. -
PROTAC Linker
4-((tert-Butoxycarbonyl)(methyl)amino)butanoic acid serves as a versatile PROTAC linker, critical for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enabling the selective degradation of proteins within cellular pathways. It is valuable in research applications focused on protein modulation and therapeutic development in cancer and neurodegenerative diseases. -
PROTAC Linker
tert-Butyl 3-(prop-2-yn-1-yloxy)azetidine-1-carboxylate serves as a PROTAC linker, facilitating targeted protein degradation through the formation of PROTACs. This compound allows for the selective modulation of protein levels in cellular systems, making it a valuable tool in drug discovery and research applications aimed at studying protein function and therapeutic intervention. Its unique structure enables efficient conjugation to ligands and E3 ligases, thereby enhancing the potency of PROTAC molecules. -
PROTAC Linker
1,15-Pentadecanediol is a versatile PROTAC linker designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound exhibits favorable solubility and stability characteristics, enhancing the efficiency of targeted protein degradation studies. Its application in research enables the development of novel therapeutic strategies by allowing precise modulation of protein levels within cellular systems. -
PROTAC Linkers
Biotin-C5-amino-C5-amino is a versatile PROTAC linker featuring an alkyl chain structure designed for efficient PROTAC synthesis. This compound facilitates the targeted degradation of proteins by linking E3 ligases to the target protein, enhancing the specificity and efficacy of the degradation process. It is essential for researchers developing novel protein degradation strategies in drug discovery and therapeutic applications. -
PROTAC Linker
Tert-butyl (4-(hydroxymethyl)benzyl)(methyl)carbamate serves as a valuable PROTAC linker, facilitating the design and synthesis of PROTAC molecules. Its structural attributes enhance the efficiency of target protein degradation through the ubiquitin-proteasome pathway. This compound is essential for researchers exploring targeted protein degradation mechanisms and the development of innovative therapeutic strategies.
