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PDK1

PDK1

Catalog No.	Product Name	Application	Product Information
A12881	BX-517	PDK1 inhibitor	BX-517 is a potent and selective inhibitor of PDK1 that binds to the ATP binding pocket of the protein (IC50 = 6 nM).
A11148	BX-795	PDK-1 inhibitor	BX-795 is a potent PDK1 inhibitor that blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induced apoptosis.
A11149	BX-912	PDK1 inhibitor	BX-912 is an inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1).
A12767	GSK 2334470	PDK1 Inhibitor	GSK 2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM). PDK-1
A11511	NVP-BAG956	PI3K/PDK-1 Inhibitor	NVP-BAG956 acts as a potent, reversible, and ATP-competitive PI 3-K/PDK1 dual kinase inhibitor, displaying much reduced potency against VEGFR1 (IC50 = 2.56 uM) and little or no activity toward a panel of 15 other kinases (IC50 >10 uM).
A10681	OSU-03012	PDK-1 inhibitor	OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types. PDK-1
A16185	PDK1 inhibitor	PDK1 inhibitor	PDK1 inhibitor, potent, ATP-competitive and selective dual PI3K and PDPK1 inhibitor (IC50 values 34 nM and 94 nM for PDK1 and p-T308-PKB inhibition, respectively.
A11528	PDK1 inhibitor	PDK1 inhibitor	PDK1 inhibitor is a potent and selective inhibitor of PDK1 with potential as anticancer agent.
A13484	PS 48	PDK1 inhibitor	PS 48 is an allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM).