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PDK-1 inhibitor

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Catalog No. A10681

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
OSU-03012 5mg A10681-5

Regular Price: $50.00

Special Price: $45.00

OSU-03012 25mg A10681-25

Regular Price: $160.00

Special Price: $144.00

OSU-03012 50mg A10681-50

Regular Price: $300.00

Special Price: $270.00

OSU-03012 100mg A10681-100

Regular Price: $470.00

Special Price: $423.00

OSU-03012 10mM * 1mL in DMSO A10681-10mM-D

Regular Price: $90.00

Special Price: $81.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.


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Chemical Information

Catalog Num A10681
Actions Inhibitor
M. Wt 460.2
Formula C26H19F3N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 742112-33-0
Synonyms N/AAR-12, OSU03012

Biological Activity

OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.
PDK-1 (Cell-free assay)
5 μM


Solubility (25°C) * In vitro DMSO 11 mg/mL (23.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.73 mL 108.65 mL 217.3mL
0.5 mM 4.35 mL 21.73 mL 43.46 mL
1 mM 2.17 mL 10.86 mL 21.73 mL
5 mM 0.43 mL 2.17 mL 4.35 mL

*The above data is based on the productmolecular weight 460.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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