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PDK1 inhibitor

PDK1 inhibitor

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Catalog No. A16185

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PDK1 inhibitor 2610 5mg A16185-5
$80.00
PDK1 inhibitor 2610 10mg A16185-10
$140.00
PDK1 inhibitor 2610 50mg A16185-50
$550.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PDK1 inhibitor, potent, ATP-competitive and selective dual PI3K and PDPK1 inhibitor (IC50 values 34 nM and 94 nM for PDK1 and p-T308-PKB inhibition, respectively.

PDK1 inhibitor

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Chemical Information

Catalog Num A16185
Actions Inhibitor
M. Wt 421.88
Formula C25H15N5.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 853909-77-0
Synonyms N/A
SMILES C1=CC(=CN=C1)C#CC2=CC3=C4C(=CN=C3C=C2)N=CN4C5=CC=C(C=C5)CC#N.Cl

Biological Activity

Description
PDK1 inhibitor, potent, ATP-competitive and selective dual PI3K and PDPK1 inhibitor (IC50 values 34 nM and 94 nM for PDK1 and p-T308-PKB inhibition, respectively.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.7 mL 118.52 mL 237.03mL
0.5 mM 4.74 mL 23.7 mL 47.41 mL
1 mM 2.37 mL 11.85 mL 23.7 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 421.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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