Catalog No.
Product Name
Application
Product Information
Citations
-
Phenethylamine
α-Ethyl 2C-D hydrochloride is a phenethylamine derivative that acts primarily on serotonin and dopamine receptors. This compound exhibits significant psychoactive properties and has been utilized in research to explore the effects of amphetamines and their analogs. It serves as a reference standard in drug discrimination studies, particularly for understanding the pharmacological profiles of MDMA. -
Antianxiety Compound
Fluprazine is an anxiolytic compound that primarily targets neurotransmitter systems to alleviate anxiety symptoms. This compound exhibits key biological activity in modulating serotonin and dopamine receptors, making it relevant in the study of various psychiatric disorders. Researchers utilize Fluprazine for investigating therapeutic approaches in anxiety and related mood disorders. -
Neuroleptic Agent
Fenaperone hydrochloride is a neuroleptic agent that primarily targets dopamine receptors in the central nervous system. It exhibits antipsychotic properties, making it relevant for research in neurological disorders and psychiatric conditions. Its mechanism includes modulation of neurotransmitter activity, contributing to its potential therapeutic effects in various mental health applications. -
Drug Impurity
Pramipexole impurity 1 (2-N-Propyl pramipexole) is a chemical impurity associated with the drug Pramipexole, which targets dopamine receptors. This impurity is essential for quality control and validation studies in pharmaceutical research, ensuring the purity and safety of drug formulations. It serves as a reference compound in analytical chemistry and can facilitate the investigation of drug metabolism and pharmacokinetics. -
Drug Impurity
Ropinirole impurity 2 is a chemical impurity associated with the synthesis of Ropinirole, a dopamine receptor agonist. This compound can be utilized for analytical purposes in the assessment of drug purity and quality control in pharmaceutical research. Its presence is significant for the evaluation of Ropinirole formulations and may impact the overall efficacy and safety profile of the drug. -
Drug Impurity
Ropinirole impurity 5 is a chemical impurity associated with Ropinirole, a dopamine agonist primarily targeting the D2 and D3 dopamine receptors. This impurity is important for analytical and quality control purposes in pharmaceutical research and development. Its identification and quantification are crucial for ensuring the purity and safety of Ropinirole formulations. -
Drug Impurity
Ropinirole impurity 1 is a structural impurity derived from Ropinirole, a selective dopamine agonist primarily targeting D2 dopamine receptors. This reagent is crucial for analytical and quality control applications, serving as a reference standard for assessing the purity and quality of Ropinirole formulations. Its characterization aids in the understanding of processing variability and ensures compliance with regulatory standards in pharmaceutical development. -
Intermediate
2-Benzylaniline is an intermediate compound that serves as a precursor in the synthesis of Compound 15. This derivative exhibits affinity for the D3 dopamine receptor, with a Ki value of 4654 nM. 2-Benzylaniline is valuable in research related to mental disorders, enabling the exploration of therapeutic targets within neuropharmacology. -
Drug Impurity
Brexpiprazole impurity 1 is a chemical impurity related to the atypical antipsychotic Brexpiprazole, which primarily targets serotonin and dopamine receptors. This impurity can be utilized in the assessment of drug quality and to investigate the stability and degradation pathways of Brexpiprazole. Its presence may influence the pharmacological profile and safety evaluations in related research applications. -
Drug Impurity
Paliperidone impurity 3 is a known impurity of the antipsychotic agent Paliperidone, which primarily targets dopamine receptors. This compound is utilized in pharmaceutical research for quality control and to assess the purity of Paliperidone formulations. It serves as a crucial reference standard in the development and validation of analytical methods, ensuring compliance with regulatory standards in drug production. -
Piperazine
1-Benzyl-3-methylpiperazine is a piperazine derivative that primarily functions as a monoamine receptor ligand. It exhibits significant activity at various serotonin and dopamine receptors, making it a valuable compound for research in neuropharmacology. This reagent is often utilized in studies exploring the effects of psychoactive substances and the mechanisms underlying mood regulation. -
Piperazine
MDBP hydrochloride is a piperazine derivative that acts as a central nervous system modulator. It demonstrates significant biological activity by influencing serotonin and dopamine receptors, making it a valuable tool for neuroscience research. This compound is useful for investigating psychiatric disorders and exploring the pharmacological effects of piperazine analogs. -
Amisulpride Photodegradation Product
Amisulpride N-oxide is a photodegradation product of Amisulpride, which acts as a dopamine D2/D3 receptor antagonist. This compound may be relevant for studies investigating the stability and degradation pathways of Amisulpride under light exposure. Its characterization can aid researchers in understanding the pharmacokinetics and metabolic processes associated with dopamine receptor modulation. -
Piperazine
2-BZP is a piperazine compound that functions as a central nervous system stimulant by targeting serotonin and dopamine receptors. Its primary biological activity includes modulation of neurotransmitter release, making it useful in research related to neuropharmacology and behavioral studies. 2-BZP serves as a valuable tool for elucidating the mechanisms of psychostimulant effects and exploring potential therapeutic applications. -
Piperazine
1-(3-Chloro-4-fluorophenyl)piperazine hydrochloride is a piperazine derivative that acts as a potent and selective modulator of various neurotransmitter systems. This compound is primarily utilized in neuroscience research to investigate its effects on serotonin and dopamine receptors, contributing to the understanding of mood disorders and psychotropic drug action. Its unique chemical structure makes it valuable for studies related to pharmacology and medicinal chemistry. -
Drug Derivative
SKF 83692 is a potent derivative that primarily targets dopamine receptors, specifically D1-like receptors. This compound exhibits notable biological activity in modulating dopaminergic signaling, making it valuable for research in neuropharmacology and the study of dopamine-related disorders. SKF 83692 serves as an important tool for investigating receptor pharmacology and the potential therapeutic effects of dopamine modulation in various neurological conditions. -
Benzofuran
5-EAPB hydrochloride is a benzofuran derivative that acts primarily as a serotonin and dopamine receptor modulator. This compound is known for its psychoactive properties and has been used in neurological research to explore the mechanisms of mood regulation and cognitive function. Its ability to enhance serotonergic transmission makes it a valuable tool for studying various neuropharmacological applications. -
Drug Derivative
N-Acetyl-3,4-MDMC is a drug derivative structurally related to 3,4-methylenedioxymethcathinone. This compound has been investigated for its psychoactive properties and potential interactions with monoamine transporters, particularly serotonin and dopamine receptors. Research applications include studies on its effects on neural activity and behavioral responses in various models of neurotransmission. -
Drug Derivative
Methiomeprazine is a drug derivative primarily targeting the dopaminergic system. It exhibits significant antipsychotic and sedative properties, making it valuable in the treatment of various psychiatric disorders. Methiomeprazine is commonly used in research related to neuropharmacology and the exploration of dopamine receptor interactions. Its efficacy in managing behavioral symptoms also positions it as a candidate for studies on mental health therapies. -
Biochemical Assay Reagent
Duoperone is a neuroleptic agent that acts primarily by antagonizing dopamine receptors. This compound exhibits significant antiemetic properties in various animal models, making it valuable for studies related to nausea and psychotic disorders. Its applications extend to biochemical assays that investigate neurotransmitter dynamics and the pharmacological evaluation of antipsychotic drugs. -
Stable Isotope
Apomorphine hydrochloride-d4 is a deuterium-labeled derivative of Apomorphine hydrochloride, designed as a stable isotope for metabolic studies. This compound serves as a valuable tool in pharmacokinetic and drug metabolism research, enabling precise tracking of Apomorphine in biological systems. Its application extends to studies on dopamine receptor modulation and related neurological pathways, facilitating a deeper understanding of dopaminergic signaling and its implications in various disorders. -
Stable Isotope
trans-Dihydro Tetrabenazine-d7 is a deuterium-labeled stable isotope of (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol. It serves as a valuable tool for isotopic labeling in biochemical research. Its distinct mass characteristics facilitate studies on pharmacokinetics, metabolism, and drug interactions, particularly in the context of neuropharmacology and the investigation of dopamine receptors. -
Stable Isotope
rac-Rotigotine-d3 methyl ether is a deuterium-labeled analogue of the dopamine agonist rotigotine, targeting dopamine D2 and D3 receptors. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research, enabling precise tracking of rotigotine's distribution and metabolism in biological systems. Its application enhances the understanding of dopamine receptor activity and drug interactions. -
Stable Isotope
7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine-d8 is a deuterium-labeled derivative of Quetiapine, a psychopharmacological agent primarily targeting serotonin and dopamine receptors. This stable isotope is utilized in pharmacokinetic studies to accurately track drug metabolism and bioavailability. It serves as a valuable tool for researchers investigating the pharmacodynamics and pharmacogenomics of antipsychotic therapies. -
Stable Isotope
Chlorproethazine-d10 hydrochloride is a deuterium-labeled derivative of Chlorproethazine hydrochloride, functioning as a stable isotope. This compound is primarily utilized in pharmacokinetic studies and drug metabolism research, allowing for enhanced tracking and quantification in biological systems. Its incorporation of deuterium facilitates improved analytical precision in investigations involving the pharmacodynamics of antagonists at dopamine receptors. -
Drug Impurity
Ropinirole impurity 3 is a characterized impurity associated with the dopamine receptor agonist Ropinirole. This compound is crucial for assessing the purity and quality of Ropinirole in pharmaceutical formulations. It aids in the development and validation of analytical methods required for regulatory compliance in drug manufacturing. -
Drug Impurity
Fluphenazine decanoate impurity 8 is a known impurity associated with Fluphenazine decanoate, an antipsychotic medication primarily targeting dopamine receptors. This compound can be utilized in analytical research to evaluate the purity of pharmaceutical formulations and support drug development processes. Its presence may affect pharmacokinetics and pharmacodynamics, making it essential for quality control and safety assessments in therapeutic applications. -
Racemate
(±)-Levomepromazine is a racemic mixture primarily targeting dopamine receptors. It exhibits notable antipsychotic activity, making it relevant for research in psychiatry and neuropharmacology. Its effects on neurotransmitter pathways are valuable for studying various psychiatric disorders and the mechanisms of psychotropic agents. -
Dopamine Receptor Antagonist
Droperidol is a butyrophenone compound primarily acting as a dopamine receptor antagonist. It inhibits the activation of GABA(A) and neuronal nicotinic acetylcholine receptors (nAChR), demonstrating IC50 values of 12.6 nM and 5.8 μM, respectively. This compound exhibits notable anesthetic and sedative properties, making it useful in research related to neuropharmacology and anesthesiology. -
Dopamine Receptor Inhibitor
Fluphenazine dihydrochloride is a potent dopamine receptor antagonist primarily targeting dopamine D2 receptors in the mesolimbic, nigrostriatal, and tuberoinfundibular pathways. This phenothiazine derivative also exhibits the ability to inhibit neuronal voltage-gated sodium channels. Its key biological activities include the suppression of Methylphenidate-induced stereotyped behaviors and climbing in murine models. Fluphenazine dihydrochloride is widely utilized in research related to psychosis, diabetic peripheral neuropathy, and may also have implications for the inhibition of SARS-CoV-2. -
D2/D3 Dopamine Receptor Antagonist
Tiapride hydrochloride is a selective antagonist of the D2 and D3 dopamine receptors, exhibiting IC50 values of 110-320 nM and 180 nM, respectively. This compound is recognized for its anti-dyskinetic and anxiolytic activities, making it valuable in neurological research. Tiapride hydrochloride is utilized as a neuroleptic agent, contributing to studies on movement disorders and anxiety-related conditions. -
Dopamine Receptor Antagonist
Clebopride malate is an orally active antagonist of dopamine D2 receptors, exhibiting significant antiemetic and prokinetic properties. This compound is useful in research focused on functional gastrointestinal disorders, providing valuable insights into dopaminergic modulation in gastrointestinal motility and emesis. Clebopride malate may serve as an important tool for understanding the underlying mechanisms of these conditions. -
Antipsychotic Agent
Dixyrazine is a phenothiazine derivative that functions as an antipsychotic agent through its antagonism of dopamine receptors. It has demonstrated efficacy in preventing brain edema induced by intracarotid injection of protamine sulfate. This compound is relevant for research applications in neuropharmacology and the investigation of psychotropic mechanisms. -
Catecholamine Neurotransmitter
Dopamine is a catecholamine neurotransmitter primarily produced in the substantia nigra, ventral tegmental area, and hypothalamus. It is essential for various neural processes and physiological functions. Dopamine exerts its biological effects predominantly through D2 dopamine receptors, leading to endocytosis of VEGFR2, which is vital for angiogenesis. This compound is widely utilized in research focusing on neurological disorders, cardiovascular functions, and cellular signaling pathways. -
Dopamine Receptor Antagonist
Fluphenazine is a potent dopamine receptor antagonist primarily targeting postsynaptic dopamine D2 receptors in the mesolimbic, nigrostriatal, and tuberoinfundibular pathways. This phenothiazine derivative exhibits substantial biological activity by inhibiting dopamine signaling, making it useful for studying psychosis and diabetic peripheral neuropathy. Additionally, Fluphenazine has shown potential in inhibiting SARS-CoV-2, contributing to its relevance in current research focused on neuropharmacology and viral pathogenesis. -
Dopamine Receptor D2 Antagonist
Promazine is a dopamine receptor D2 antagonist that primarily functions by inhibiting dopaminergic neurotransmission. This compound is utilized in research related to psychotic disorders and provides insights into dopamine-mediated pathways. Its application extends to studying the neuropharmacology of antipsychotic treatments and understanding the mechanisms underlying various psychiatric conditions. -
Dopamine Receptor Antagonist
Thioridazine is a dopamine receptor D2 antagonist known for its potent antipsychotic and anxiolytic properties. In addition to its neuropharmacological effects, Thioridazine significantly inhibits the PI3K-Akt-mTOR signaling pathway, exhibiting anti-angiogenic activity. It has demonstrated antiproliferative effects and the ability to induce apoptosis in various cancer cell types, with a particular efficacy in targeting cancer stem cells (CSCs). These characteristics make Thioridazine a valuable compound for research in neurobiology and cancer therapeutics. -
Dopamine Receptor Antagonist
N-(p-Aminophenethyl)spiperone is a selective antagonist of D2-like dopamine receptors. This compound binds specifically to the ligand recognition sites of functional D2 and D3 receptors, making it a valuable tool for researchers studying dopamine signaling pathways. N-(p-Aminophenethyl)spiperone is primarily used for labeling, localizing, and identifying D2 and D3 dopamine receptors in various biological systems. -
Antipsychotic Agent
Clopipazan is a potent antipsychotic agent that primarily targets dopamine receptors in the brain. Its primary mechanism of action involves modulating dopaminergic activity, which contributes to its therapeutic effects in the treatment of various psychiatric disorders, including schizophrenia. Clopipazan is utilized in research to explore neural pathways and potential therapeutic interventions for mental health conditions. -
Antipsychotic Agent
Clomacran is a potent antipsychotic agent that primarily targets dopamine receptors in the brain, particularly the D2 receptor. It exhibits significant efficacy in alleviating symptoms associated with various psychotic disorders. This compound is widely utilized in preclinical research to investigate its neuropharmacological effects and potential therapeutic applications in the treatment of schizophrenia and other related conditions. -
Active Compound
Fluphenazine enanthate is a long-acting injectable antipsychotic compound that primarily targets dopamine receptors. It is utilized in the treatment of schizophrenia, providing sustained therapeutic effects that assist in managing acute and chronic symptoms of the disorder. Researchers can explore its pharmacological properties and effects on neurotransmitter dynamics in various experimental models related to psychosis and mental health disorders. -
Anti-Schizophrenia Agent
Zuclopenthixol decanoate is an antipsychotic compound that primarily targets dopamine receptors in the central nervous system. This long-acting formulation is utilized in research focused on schizophrenia and other serious mental health disorders, offering insights into therapeutic interventions and treatment protocols. Its sustained release properties allow for improved management of symptoms, making it valuable in preclinical and clinical studies. -
LAI Antipsychotic
Aripiprazole Lauroxil is a long-acting injectable antipsychotic targeting dopamine receptors D2 and D4. It is an N-acyloxymethyl proagent of Aripiprazole, which undergoes enzymatic cleavage by esterases in the body to yield N-hydroxymethyl aripiprazole and lauric acid, further converting to aripiprazole and formaldehyde. This compound exhibits therapeutic activity in the management of schizophrenia and is utilized in research related to psychotropic medications and long-term treatment strategies. -
Antipsychotic Agent
Carphenazine is a phenothiazine antipsychotic agent that primarily targets dopamine receptors in the central nervous system. It exhibits significant antipsychotic activity, making it useful for studying the mechanisms underlying chronic schizophrenic psychoses. This compound is employed in research to better understand therapeutic interventions for various psychotic disorders.
