Fig. 1 · Structure
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Fluphenazine
Dopamine Receptor Antagonist
Fluphenazine is a potent dopamine receptor antagonist primarily targeting postsynaptic dopamine D2 receptors in the mesolimbic, nigrostriatal, and tuberoinfundibular pathways. This phenothiazine derivative exhibits substantial biological activity by inhibiting dopamine signaling, making it useful for studying psychosis and diabetic peripheral neuropathy. Additionally, Fluphenazine has shown potential in inhibiting SARS-CoV-2, contributing to its relevance in current research focused on neuropharmacology and viral pathogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 69-23-8 |
| Applications | Dopamine Receptor Antagonist |
| Formula | C22H26F3N3OS |
| Molecular Weight | 437.52 |
| SMILES | OCCN1CCN(CC1)CCCN2C3=C(SC4=C2C=C(C=C4)C(F)(F)F)C=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.