Fig. 1 · Structure
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Aripiprazole Lauroxil
LAI Antipsychotic
Aripiprazole Lauroxil is a long-acting injectable antipsychotic targeting dopamine receptors D2 and D4. It is an N-acyloxymethyl proagent of Aripiprazole, which undergoes enzymatic cleavage by esterases in the body to yield N-hydroxymethyl aripiprazole and lauric acid, further converting to aripiprazole and formaldehyde. This compound exhibits therapeutic activity in the management of schizophrenia and is utilized in research related to psychotropic medications and long-term treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1259305-29-7 |
| Applications | LAI Antipsychotic |
| Formula | C36H51Cl2N3O4 |
| Molecular Weight | 660.71 |
| SMILES | CCCCCCCCCCCC(OCN1C(CCC2=C1C=C(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)C=C2)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.