Fig. 1 · Structure
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Droperidol
Dopamine Receptor Antagonist
Droperidol is a butyrophenone compound primarily acting as a dopamine receptor antagonist. It inhibits the activation of GABA(A) and neuronal nicotinic acetylcholine receptors (nAChR), demonstrating IC50 values of 12.6 nM and 5.8 μM, respectively. This compound exhibits notable anesthetic and sedative properties, making it useful in research related to neuropharmacology and anesthesiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 548-73-2 |
| Applications | Dopamine Receptor Antagonist |
| Formula | C22H22FN3O2 |
| Molecular Weight | 379.43 |
| Synonyms | Dehydrobenzperidol |
| SMILES | O=C1NC2=CC=CC=C2N1C3=CCN(CCCC(C4=CC=C(F)C=C4)=O)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.