Fig. 1 · Structure
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Thioridazine
Dopamine Receptor Antagonist
Thioridazine is a dopamine receptor D2 antagonist known for its potent antipsychotic and anxiolytic properties. In addition to its neuropharmacological effects, Thioridazine significantly inhibits the PI3K-Akt-mTOR signaling pathway, exhibiting anti-angiogenic activity. It has demonstrated antiproliferative effects and the ability to induce apoptosis in various cancer cell types, with a particular efficacy in targeting cancer stem cells (CSCs). These characteristics make Thioridazine a valuable compound for research in neurobiology and cancer therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 50-52-2 |
| Applications | Dopamine Receptor Antagonist |
| Formula | C21H26N2S2 |
| Molecular Weight | 370.57 |
| SMILES | CSC(C=C1N2CCC3N(C)CCCC3)=CC=C1SC4=C2C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.