Thioridazine is a dopamine receptor D2 antagonist known for its potent antipsychotic and anxiolytic properties. In addition to its neuropharmacological effects, Thioridazine significantly inhibits the PI3K-Akt-mTOR signaling pathway, exhibiting anti-angiogenic activity. It has demonstrated antiproliferative effects and the ability to induce apoptosis in various cancer cell types, with a particular efficacy in targeting cancer stem cells (CSCs). These characteristics make Thioridazine a valuable compound for research in neurobiology and cancer therapeutics.
Thioridazine is a dopamine receptor D2 antagonist known for its potent antipsychotic and anxiolytic properties. In addition to its neuropharmacological effects, Thioridazine significantly inhibits the PI3K-Akt-mTOR signaling pathway, exhibiting anti-angiogenic activity. It has demonstrated antiproliferative effects and the ability to induce apoptosis in various cancer cell types, with a particular efficacy in targeting cancer stem cells (CSCs). These characteristics make Thioridazine a valuable compound for research in neurobiology and cancer therapeutics.
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