Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
3'-Deoxy-3'-fluoro-6-azauridine is a purine nucleoside analogue that selectively inhibits DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting cellular apoptosis and disrupting nucleotide metabolism. It is a valuable tool for research applications focused on cancer biology and therapeutic investigations targeting nucleoside metabolism. -
Hypoxanthine Analog
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog that selectively targets key metabolic pathways involving purine metabolism. This compound exhibits notable anti-inflammatory properties and serves as a potential endogenous inhibitor of poly(ADP-ribose) polymerase (PARP). Its cytoprotective effects are attributed to the inhibition of PARP activity, which prevents peroxynitrite-induced mitochondrial depolarization and subsequent oxidative stress. Additionally, hypoxanthine analogs have applications in research related to cellular responses to hypoxia. -
Purine Nucleoside Analog
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog that exhibits significant antitumor activity. This compound targets indolent lymphoid malignancies through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. It is a valuable reagent for cancer research, enabling the investigation of nucleotide-related pathways and therapeutic approaches in oncology. -
Purine Nucleoside Analog
5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development strategies. -
Uridine Analog
1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione is a uridine analog that targets nucleoside pathways. This compound exhibits potential antiepileptic properties and is suitable for investigating anticonvulsant and anxiolytic activities. Additionally, it holds promise for the development of novel agents aimed at managing hypertension. -
Adenosine Analog
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine is an adenosine analog that primarily acts as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for cancer research. It serves as a useful tool in studies focused on adenosine receptor modulation and vascular biology. -
Nucleoside Metabolite
1,2-Dihydroxy-5-(methylthio)-1-penten-3-one is a nucleoside metabolite known for its role in various biochemical pathways. This compound exhibits significant biological activity, contributing to studies focused on nucleotide metabolism and cellular signaling. It serves as a valuable tool in research applications aimed at understanding nucleoside dynamics and their implications in cellular processes. -
Purine Nucleoside Analog
N6-Furfuryl-2’-C-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research and therapeutic development. This compound is utilized in studies focused on nucleoside analogs and their potential applications in oncology. -
Nucleoside Metabolite
L-Dopachrome is a nucleoside metabolite that plays a critical role in the biosynthesis and metabolism of melanin. It serves as an intermediate in the enzymatic conversion of L-DOPA to eumelanin and has been studied for its effects on pigmentation processes and potential implications in neurological health. This compound is valuable for research applications related to melanin synthesis, skin biology, and neurodegenerative conditions. -
Antitumor Agent
Flurocitabine hydrochloride is an antitumor agent that exerts its effects by undergoing hydrolysis in vivo to yield two active metabolites: arabinosyl-fluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU). These metabolites are involved in disrupting nucleic acid synthesis, making Flurocitabine hydrochloride a valuable tool in cancer research. Its ability to target tumor growth positions it as a significant compound for studies focused on chemotherapy and the development of novel anticancer therapies. -
Purine Nucleoside Analog
5-Bromo-3’-deoxy-3’-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is essential for studying the effects of nucleoside analogs in oncological applications. -
Purine Nucleoside Analog
2'-C-Ethynyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis. Additionally, 2'-C-Ethynyluridine serves as a click chemistry reagent due to its alkyne group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This dual functionality makes it a valuable tool in chemical biology and therapeutic research. -
Adenosine Analog
3’-O-Propargyladenosine is an adenosine analog that primarily targets adenosine receptors, acting as a vasodilator and exhibiting potential anti-cancer properties. It serves as a valuable tool in research applications involving click chemistry, due to its alkyne functional group, which facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This compound is instrumental in the study of biochemical pathways and therapeutic interventions related to adenosine signaling and vascular biology. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-beta-L-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in treating indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound acts as a versatile click chemistry reagent, featuring an azide group capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne, DBCO, or BCN-containing molecules, making it useful for various biochemical applications. -
Nucleoside Metabolite
(2-Amino-1-hydroxyethyl)phosphonate, also known as 1-Hydroxy-2-aminoethylphosphonic acid, functions as a nucleoside metabolite. This compound plays a significant role in biochemical pathways associated with nucleotide metabolism and cell signaling. Its research applications include studies on metabolic processes, neuropharmacology, and the investigation of phosphonate derivatives in various biological systems. -
Purine Nucleoside Analog
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine functions as a purine nucleoside analog. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through its ability to inhibit DNA synthesis and promote apoptosis. It is a valuable tool for research in cancer biology, particularly in studies focused on therapeutic strategies targeting nucleoside metabolism and cell proliferation. -
Thymidine Analog
2',3',5'-Tri-O-acetyl-5-cyanouridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound can serve as a valuable tool for labeling cells and monitoring DNA synthesis in various biological systems. Its utility in research makes it ideal for studies involving DNA replication and cell proliferation. -
Purine Nucleoside Analog
N6-iso-Propyl-2’-O-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic studies. This compound is instrumental for researchers investigating novel treatments for hematologic cancers and exploring the molecular pathways associated with nucleoside analogs. -
Purine Nucleoside Analog
3'-O-DMTr-thymidine 5'-CE phosphoramidite is a purine nucleoside analog designed for nucleic acid synthesis and incorporation into oligonucleotides. It exhibits significant biological activity by inhibiting DNA synthesis and facilitating apoptosis, making it valuable in research focused on antitumor therapies. This compound is particularly relevant for exploring novel treatments for indolent lymphoid malignancies. -
Purine Nucleoside Analog
3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog that demonstrates potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valued in oncological research for its potential to elucidate mechanisms of tumorigenesis and therapeutics. -
Purine Nucleoside Analog
Alpha-5-Methyluridine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to cell cycle disruption and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Adenosine Analog
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog that primarily targets adenosine receptors. It exhibits biological activities such as smooth muscle relaxation and has demonstrated potential in inhibiting cancer progression. This compound is useful in various research applications, particularly in the development of nucleic acid-based therapeutics and the study of adenosine receptor signaling pathways. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’-O-(2-methoxyethyl)uridine is a purine nucleoside analog known for its anticancer properties. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for exploring cancer biology and test therapeutic approaches in research applications. -
Purine Nucleoside Analog
3’-Deoxy-N6-methyladenosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its molecular mechanism primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research focused on cancer biology and therapeutic approaches targeting nucleoside metabolism. -
Purine Nucleoside Analog
3'-Deoxy-3'-fluoro-beta-D-xylo-inosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptotic pathways in cancer cells. This compound is valuable for research into cancer therapeutics and mechanisms of purine metabolism. -
Sulfur-containing Metabolite
S-(Indolylmethylthiohydroximoyl)-L-cysteine is a secondary sulfur-containing metabolite associated with glucosinolates. It exhibits significant biological activity relevant to plant defense mechanisms and may play a role in the modulation of enzymatic processes. This compound is valuable for research applications related to metabolomics, phytochemistry, and the study of sulfur metabolism in various biological systems. -
Purine Nucleoside Analog
3’-Azido-N6-benzoyl-3’-deoxyadenosine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is also a versatile click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring alkyne, DBCO, or BCN groups. Its unique properties make it valuable for various biochemical and molecular biology applications. -
Purine Nucleoside Analog
3’-Deoxy-3-deazauridine is a purine nucleoside analogue that effectively targets indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound shows promise in various anticancer research applications, particularly in studying treatments for hematological malignancies. -
Uridine Analog
2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite is a uridine analog that targets nucleotide synthesis pathways. This compound exhibits potential antiepileptic properties, making it a useful tool for investigating anticonvulsant and anxiolytic activities. Additionally, it may contribute to the development of novel antihypertensive agents in chemical research applications. -
Purine Nucleoside Analog
N6-Benzoyl-7’-OH-N-trityl morpholino adenine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized to study the therapeutic potential and cellular pathways associated with purine metabolism and tumorigenesis. -
Purine Nucleoside Analog
5-Carboxymethyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is primarily utilized in cancer research and therapeutic studies focused on lymphoid malignancies. -
Thymidine Analog
3’-beta-C-Methyl-5-methyluridine is a thymidine analogue that acts as a nucleotide substrate. This compound exhibits insertional activity towards replicated DNA, making it useful for labeling cells and investigating DNA synthesis dynamics. It has potential applications in molecular biology and cancer research, facilitating studies on nucleic acid behavior and cellular proliferation. -
Nucleoside Metabolite
Docosanoyl-CoA is a nucleoside metabolite involved in lipid metabolism. This compound plays a crucial role in the biosynthesis of fatty acids and serves as an acyl donor in various metabolic reactions. It is useful for research applications focused on fatty acid synthesis and metabolic pathways in cellular biology. -
Purine Nucleoside Analog
Uridine 5-oxyacetic acid methyl ester is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studies exploring novel therapeutic strategies and understanding the pathways involved in tumor cell proliferation and survival. -
Purine Nucleoside Analog
3',5'-Di-O-acetyl-2'-O-methyl-6-chloro-2-aminopurine riboside is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis, contributing to its efficacy in cancer research. Its utilization in studies targeting cancer cell proliferation makes it a valuable tool for investigating therapeutic strategies in oncology. -
Nucleoside Metabolite
N2-Succinyl-L-ornithine is a nucleoside metabolite that serves as an intermediate in the urea cycle and plays a role in nitrogen metabolism. This compound is significant for studying metabolic pathways and can be utilized in research related to amino acid metabolism and enzyme regulation. Its biochemical properties make it valuable for investigations into cellular metabolism and potential therapeutic applications in metabolic disorders. -
Purine Nucleoside Analog
N3-Ethyl pseudouridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research into cancer therapies targeting nucleoside metabolism and cellular proliferation. -
Purine Nucleoside Analog
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis, contributing to its effectiveness in cancer research. It serves as a valuable tool for studying the mechanisms of cancer biology and evaluating potential therapeutic strategies in oncology. -
Nucleoside Metabolite
L-Selenocystathionine is a seleno amino acid metabolite that participates in the synthesis and regulation of various biological molecules. Its primary mechanism involves the involvement in sulfur metabolism, acting as a precursor in the generation of selenium-containing compounds. This compound is of interest in research applications related to oxidative stress and sulfur metabolism in cells. -
Purine Nucleoside Analog
N6-(3-Trifluoromethylbenzyl)-3’-deoxyadenosine is a purine nucleoside analog known for its significant antitumor activity. This compound targets indolent lymphoid malignancies, employing mechanisms such as inhibition of DNA synthesis and induction of apoptosis. Its efficacy makes it a valuable tool for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-5-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, providing insights into therapeutic strategies targeting nucleoside metabolism and cancer cell proliferation. -
Purine Nucleoside Analog
2′,5′-Dideoxy-5′-iodouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is suitable for research applications focused on cancer treatment development and the exploration of nucleoside analogs in therapeutic strategies. -
Nucleoside Metabolite
N-Methylethanolamine phosphate is a nucleoside metabolite that plays a crucial role in cellular signaling and metabolism. It is involved in various biochemical pathways, including those related to phospholipid synthesis and membrane dynamics. This compound can be utilized in research focused on metabolic studies, cell signaling, and the elucidation of nucleoside functions in physiological processes. -
Thymidine Analog
5-Hydroxymethyl xylouridine is a thymidine analog that exhibits insertional activity towards replicated DNA. As a biolabeling agent, it enables the tracking of DNA synthesis in both cellular and molecular research applications. This compound is particularly useful for studies involving nucleic acid metabolism and cellular proliferation. -
Purine Nucleoside Analog
3’-dC(Bz)-2’-phosphor amidite is a purine nucleoside analog that exhibits significant biological activity in anticancer research. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool for targeting indolent lymphoid malignancies. Its role in cancer therapeutics underscores its potential for advancing research in oncology and related fields. -
Purine Nucleoside Analog
3',5'-Di-O-benzoyl thymidine is a purine nucleoside analog that exerts its biological activity through the inhibition of DNA synthesis and the induction of apoptosis. This compound demonstrates broad anticancer potential, particularly in the treatment of indolent lymphoid malignancies. Its applications in chemical research make it a valuable tool for studying mechanisms of cancer cell proliferation and therapeutic resistance. -
Histidine Precursor
Imidazole-4-pyruvic acid is a biologically relevant precursor of histidine, generated through the action of histidine transaminase. This compound serves as a valuable reagent for selective histidine labeling in proteins overexpressed in E. coli, facilitating the study of protein structure and function. Its application in research enables precise manipulation of proteins for various biochemical and biophysical analyses. -
Nucleoside Metabolite
Haemulcholic acid is a nucleoside metabolite that plays an essential role in nucleotide metabolism. It has demonstrated potential biological activity in regulating cellular energy homeostasis and influencing metabolic pathways. This compound is useful in research applications focused on cellular metabolism, signaling pathways, and the pharmacological effects of nucleosides. -
Purine Nucleoside Analog
3’-Deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is valuable for research aimed at understanding the molecular mechanisms of cancer and developing novel therapeutic strategies. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is a purine nucleoside analog that exerts significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound facilitates investigations into nucleoside metabolism and the efficacy of chemotherapeutic strategies.
