5-(3-Azidopropyl)uridine is a thymidine analog that displays insertional activity towards replicated DNA, making it valuable in studies of DNA synthesis and cellular labeling. This compound features an azide group, allowing it to function as a click chemistry reagent. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, facilitating diverse applications in chemical biology.
5-(3-Azidopropyl)uridine is a thymidine analog that displays insertional activity towards replicated DNA, making it valuable in studies of DNA synthesis and cellular labeling. This compound features an azide group, allowing it to function as a click chemistry reagent. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, facilitating diverse applications in chemical biology.
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