Fig. 1 · Structure

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5-Phenyluracil

Thymidine Phosphorylase Inhibitor

5-Phenyluracil is a potent inhibitor of thymidine phosphorylase, an enzyme involved in nucleoside metabolism. This compound exhibits significant anti-tumor activity by disrupting the salvage pathway of nucleotides, making it relevant for cancer research. Its selective inhibition of thymidine phosphorylase highlights its potential utility in exploring cancer therapeutics and related biological pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 15761-83-8
Applications Thymidine Phosphorylase Inhibitor
Formula C10H8N2O2
Molecular Weight 188.18
SMILES
O=C1NC=C(C=2C=CC=CC2)C(=O)N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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