2'-O-Propargyluridine

Catalog No.: A56519
Nucleoside Analog
2'-O-Propargyluridine is a nucleoside analog specifically designed for the synthesis of nucleic acids. Exhibiting properties that facilitate the formation of modified oligonucleotides, it serves as a versatile building block in research applications focusing on gene expression and RNA interference. Its unique structure provides potential advantages in enhancing the stability and binding affinity of nucleic acid strands.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2'-O-Propargyluridine is a nucleoside analog specifically designed for the synthesis of nucleic acids. Exhibiting properties that facilitate the formation of modified oligonucleotides, it serves as a versatile building block in research applications focusing on gene expression and RNA interference. Its unique structure provides potential advantages in enhancing the stability and binding affinity of nucleic acid strands.
Product Information
Catalog NumA56519
FormulaC12H14N2O6
Molecular Weight282.25
CAS Number129778-58-1
SMILESO[C@H]1[C@@H](OCC#C)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO
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