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3'-O-TBDMS-2'-F-dA(Bz)

Nucleoside Analog

3'-O-TBDMS-2'-F-dA(Bz) is a nucleoside analog with a primary mechanism of incorporation into nucleic acid sequences. This compound serves as a crucial building block for the synthesis of modified nucleotides, enabling researchers to investigate nucleic acid function and stability. Its fluorinated structure enhances the stability and binding affinity of nucleic acid constructs, making it useful in various applications, including antisense oligonucleotide design and gene expression studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1244763-25-4
Applications	Nucleoside Analog
Formula	C₂₃H₃₀FN₅O₄Si
Molecular Weight	487.60
SMILES	O=C(C1=CC=CC=C1)NC2=C(N=CN3[C@@H]4O[C@H](CO)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]4F)C3=NC=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.